Status of Research

Status of Research
The Cri du Chat Research Foundation was
established in 2014 to promote and support
research on Cri Du Chat Syndrome or 5p
Minus Syndrome, an uncommon condition.

Source:https://images.app.goo.gl/BNZB6Y5Uw3h1kiKBA

Early 1980s studies showed that people with

Source: https://images.app.goo.gl/g86mtqFnLd6NBemN7
Cri-du-Chat Syndrome who were reared in
family environments and benefited from
References early intervention programs made

Cri du Chat
http://www.criduchatresearch.org/about-cri-du-chat-5p-minus
tremendous development, far beyond the
predictions of medical professionals.
http://www.criduchatresearch.org/about-us

https://www.genome.gov/Genetic-Disorders/Cri-du-
Chat#:~:text=The%20clinical%20symptoms%20of%20cri,tone
%20(hypotonia)%20in%20infancy.
Cri-du-Chat Syndrome affects language
development, with some learning to speak in Syndrome
short sentences and others using sign
https://www.mountsinai.org/health-library/diseases-conditions/
cri-du-chat-syndrome#:~:text=Cri%20du%20chat%20syndrome language.
%20is%20rare.,the%20chromosome%20to%20their%20child

https://rarediseases.org/rare-diseases/cri-du-chat-syndrome/

Prepared by:
GLADY MAE T. TRASONA
Grade 9-Dalton
 Descriptive and Nature of Cri du Possible causes of Cri du Chat
Chat Syndrome Syndrome

Cri du chat syndrome (CdCS) is a rare

Cri du chat syndrome is rare. It is caused
genetic disorder in which a variable portion
by a missing piece of chromosome 5.
of the short arm of chromosome 5 is missing
or deleted. Common symptoms include a Most cases are believed to occur during the
distinctive cry, characteristic facial features, development of the egg or sperm. A small
slow growth, and microcephaly. Affected number of cases occur when a parent
children also exhibit delays in the acquisition passes a different, rearranged form of the
of skills requiring the coordination of chromosome to their child.
muscular and mental activities, and moderate
to severe intellectual disability. Most cases
are thought to arise from spontaneous
genetic errors early in embryonic
development.

Symptoms and Physical Features

Manifested
The clinical symptoms of cri du chat
syndrome usually include a high-pitched
cat-like cry, mental disablity, delayed
development, distinctive facial features,
small head size (microcephaly), widely
spaced eyes (hypertelorism), low birth
weight and weak muscle tone (hypotonia)
in infancy.
Source: https://images.app.goo.gl/B5YKfkPHBfPMEi7o9

Source: https://images.app.goo.gl/m9dCmnHT8w6qgEAA9