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WHAT IS PARASITIC
HELMINTHS?
WHAT IS HELMINTHS?
Helminths are worm-like parasites
that survive by feeding on a living
host to gain nourishment and
protection, sometimes resulting in
illness of the host. There are a
variety of different helminths from
the very large to the microscopic.
Structure:
• Gram-positive
nonmotile, club-
shaped bacillus.
DIPHTHEROIDS
• commonly found on the skin and mucous
membranes of humans and animals. They
are also found in soil, water, and some
food products.
• often found in the healthy mouth and
pharynx. They also occur frequently on
the skin and can be isolated from the
nose and urogenital tract.
DIPHTHEROIDS
• They are important in preventing
overgrowth of harmful bacteria and in
stimulating the immune system.
• Some diphtheroids have been found to
produce substances with antimicrobial
properties, which may help to protect
against infection.
TYPES OF DIPHTHEROIDS
Cutaneous Diphtheroids
• group of bacteria that are commonly found on the
skin and mucous membranes of healthy individuals.
• found in areas such as the armpits, groin, and nose.
Lipophilic diphtheroids
• are those that have an affinity for lipids or fats.
• found in oily areas of the skin, such as the scalp and
face
Non Lipophilic diphtheroids
• are commonly found in the upper respiratory tract.
• found in areas such as the mouth, throat, and
gastrointestinal tract.
TYPES OF DIPHTHEROIDS
Anaerobic diphtheroids
• can grow in the absence of oxygen, making them
anaerobic.
• found in a variety of locations in the human body,
including the mouth, throat, and gastrointestinal
tract.
Diphtheroids producing porphyrins
• Porphyrins are molecules involved in many biological
processes, including the synthesis of heme
• Found in the human oral cavity and the
gastrointestinal tract.
STREPTOCOCCI
STREPTOCOCCI
• A Gram-positive, nonmotile, non
sporeforming, catalase-negative cocci
that occur in pairs or chains. Older
cultures may lose their Gram-positive
character. Most streptococci are
facultative anaerobes, and some are
obligate (strict) anaerobes. Most require
enriched media (blood agar)
GROUPS OF STREPTOCOCCI
• Group A beta-hemolytic streptococci
(GAS) are known for causing pharyngitis
and its sequelae, including acute
rheumatic fever and post streptococcal
glomerulonephritis. They also cause skin
infections and invasive disease. Of all the
streptococci, GAS are the most
pathogenic for humans. (beta hemolytic
streptococci)
GROUPS OF STREPTOCOCCI
• Group A hemolytic streptococcus is also
known as a causative bacterium of
streptococcal toxic shock syndrome,
which causes tissue necrosis (death of
tissue) and shock. *1Impetigo: a general
term for skin diseases whose predominant
symptoms are pustules (pus-filled blisters
on the skin) and scabs. (alpha hemolytic
streptococci)
INFECTIONS CAUSED BY
STREPTOCOCCI
• Strep throat is caused by infection with a
bacterium known as Streptococcus
pyogenes, also called group A
streptococcus. Streptococcal bacteria are
contagious. They can spread through
droplets when someone with the infection
coughs or sneezes, or through shared food
or drinks.
INFECTIONS CAUSED BY
STREPTOCOCCI
• Can cause STSS when
they spread into deep
tissues and the
bloodstream. The
bacteria can also get
into the body through
mucus membranes,
like the skin inside
the nose and throat.
INFECTIONS CAUSED BY
STREPTOCOCCI
• Rheumatic fever is a
condition that can inflame
or make the heart, joints,
brain, and skin swell.
Rheumatic fever may
develop if strep throat or
scarlet fever infections are
not treated properly or
after strep skin infections
(impetigo).
GRAM-NEGATIVE BACILLI
GRAM-NEGATIVE BACILLI
• Gram-negative bacteria (GNB)
are among the world's most
significant public health
problems due to their high
resistance to antibiotics. These
microorganisms have significant
clinical importance in hospitals
because they often require
patients to be in the intensive
care unit (ICU), and patients are
at high risk of morbidity and
mortality.
GRAM-NEGATIVE BACILLI
GRAM-NEGATIVE BACILLI
Skin flora
GENITAL ORGANS:
· Male & Female Genitals: are sterile except Vagina.
CANDIDA
ALBICANS
INFECTIONS
IN FEMALE
VAGINA YEAST INFECTION
SYMPTOMS
1. Vaginal itch
2. Vaginal soreness
3. Thick vaginal discharge, similar in consistency to
cottage cheese
4. Burning sensation around the vaginal opening,
irritated by urine
5. Redness in or around the vagina
6. Pain or discomfort during sexual contact
7. Symptoms that tend to worsen the longer you have a
yeast infection
PREVENT VAGINAL YEAST
INFECTIONS
1. Keep skin clean and dry
2. Wear loose-fitting clothing that breathes and wicks
away moisture
3. Manage blood sugar levels,avoiding spikes in glucose
levels
4. Change sanitary pads and tampons frequently during
menses
5. Don't douche!
6. Wipe rom front to back after a bowel movement
NORMAL FLORA OF THE
VAGINA
• The vagina is located close to the anus and can be
colonized by members of the fecal flora.
• Women who are prone to recurrent urinary tract
infections harbor organisms such as E coli and
Enterobacter.
• About 15-20% of women of childbearing age carry
group B streptococci in the vagina.
• B streptococci is an important causes of sepsis and
meningitis in the newborn and is acquired during
passage through the birth canal
CONJUNCTIVAL FLORA
CONJUNCTIVAL FLORA
The conjunctiva is a transparent mucous membrane
lining the internal surfaces of the eyelids and the
orbital globe. The surface is covered with stratified,
non-keratinized epithelial cells and functions as a
barrier against infection. The conjunctival flora is found
on the ocular surface of healthy individuals and under
normal conditions comprises noninfectious
microorganisms. These microorganisms have an
important role in the maintenance of normal
conjunctival functions and the prevention of ocular
infections
CONJUNCTIVAL FLORA
Staphylococcus Aureus Corynebacterium
CONJUNCTIVAL FLORA
Neisseria Gonorrhea Moraexelle keratitis
CONJUNCTIVAL FLORA
Streptococci mitis
CONJUNCTIVAL FLORA
Symptoms
• Red eye: Either unilateral, bilateral, or sequentially
bilateral.
• Discharge: Classically purulent, but may be thin or
thick muco-purulent or watery.
• Irritation, burning, stinging, discomfort.
• Tearing.
• Light sensitivity.
• Intolerance to contact lens.
• Fluctuating or decreased vision.
CONJUNCTIVAL FLORA
Prevention of Positive Conjunctival Flora
• Wash your hands often with soap and water, and help young
children do the same. Wash hands especially well after touching
someone with positive conjunctival flora or their personal items.
• Avoid touching or rubbing your eyes. This can worsen the
condition or spread it to your other eye.
• Avoid sharing personal items, such as makeup, eye drops, towels,
bedding, contact lenses and containers, and eyeglasses.
• Do not use the same eye products for your infected and non-
infected eyes.
• Stop wearing contact lenses until your eye doctor says it’s okay.
• Clean, store, and replace your contact lenses as instructed by
your eye doctor.
HOST INFECTION BY
ELEMENTS OF THE
NORMAL FLORA
HOST INFECTION BY ELEMENTS
OF THE NORMAL FLORA
• Caries, periodontal disease, abscesses,
foul-smelling discharges, and
endocarditis are hallmarks of infections
with members of the normal human flora
Endocarditis
• inflammation of the inside
lining of the heart
chambers and heart valves
(endocardium).
COMMON HELMINTHS
PARASITES
COMMON HELMINTHS
PARASITES
Helminth is a general term meaning worm. The
helminths are invertebrates characterized by
elongated, flat or round bodies. In medically
oriented schemes the flatworms or
platyhelminths (platy from the Greek root
meaning “flat”) include flukes and tapeworms.
Roundworms are nematodes (nemato from the
Greek root meaning “thread”). These groups are
subdivided for convenience according to the host
organ in which they reside, e.g., lung flukes,
extraintestinal tapeworms, and intestinal
roundworms. This chapter deals with the
structure and development of the three major
groups of helminths.
TREMATODES (FLUKES)
TREMATODES (FLUKES)
Flukes are from the class
Platyhelminthes which are flatworms,
they are parasitic worms that can infect
humans when ingested. They are flat,
oval or elongated worms with a leaf like
body, 7-8cm in size. Adult trematode has
an oral sucker on its anterior and a
ventral sucker on its posterior which
are used for attachment. The muscular
pharynx is the mouth of the flukes
which are used for sucking food from
the host. The outer layer of the fluke is
called the tegument which protects
worm and contains microvilli for
nutrient absorption
TREMATODES (FLUKES)
Flukes have both male and
females reproductive organs in
one body, the male organs
contains two (2) testes with
accessory glands and ducts
leading to a cirrus,
or penis equivalent, that extends
into the common genital atrium.
The female gonad consists of a
single(1) ovary with a seminal
receptacle and vitellaria, or yolk
glands, that connect with the
oviduct as it expands into an
ootype.
TYPES TREMATODES
(FLUKES)
Blood flukes (Schistosoma)
• can be transmitted through penetration of the skin
free swimming cercariae of schistosoma eggs,
normally found in freshwater sources with feces or
urine containing parasite eggs.
• It is flat, bilaterally
symmetrical bodies,
and segmented.
CHARACTERISTICS OF
TAPEWORMS (CESTODES)
Hermaphrodite
• Both male and female
reproductive organs in the
same organism.
Nervous System
• Pair of lateral longitudinal
nerves
• No digestive tract
• No circulatory system
CHARACTERISTICS OF
TAPEWORMS (CESTODES)
Habitat of Adult Worm
• Intestine of the definitive host
Intermediate host
• Larval stage encysted in the
tissue
ANATOMY OF TAPEWORMS
(CESTODES)
1. Head or Scolex
• Anterior Structure
• Main organ of attachment of the
worm
Rostellum
• Retractable, muscular, protruding
part used for attachment
• Armed with hook
• No rostellum, no hooks > Unarmed
• Suckers
• Used for attachment
ANATOMY OF TAPEWORMS
(CESTODES)
2. Neck
• Region of growth and actively
dividing
• Segmentation or strobilization
originates from the neck
3. Strobila
• Long, segmented body composed of
proglottids
ANATOMY OF TAPEWORMS
(CESTODES)
3 types of Proglottids
Immature Proglottid
• Male and female reproductive organs are not yet
differentiated
Mature Proglottid
• Testes and ovaries are differentiated and prominent
Gravid Proglottid
• Uterus with lateral branches is filled with eggs
ANATOMY OF TAPEWORMS
(CESTODES)
3 types of Proglottids
SPECIES OF TAPEWORMS
(CESTODES)
Taenia
solium
SPECIES OF TAPEWORMS
(CESTODES)
Taenia
saginata
SPECIES OF TAPEWORMS
(CESTODES)
Diphyllobothrium
latum
SPECIES OF TAPEWORMS
(CESTODES)
Hymenolepis
nana
SPECIES OF TAPEWORMS
(CESTODES)
Dipylidium
caninum
NEMATODES
(ROUNDWORMS)
NEMATODES (ROUNDWORMS)
Nematodes are cylindrical rather than flattened;
hence the common name roundworm. The body
wall is composed of an outer cuticle that has a
noncellular, chemically complex structure, a thin
hypodermis, and musculature. The cuticle in
some species has longitudinal ridges called alae.
The bursa, a flaplike extension of the cuticle on
the posterior end of some species of male
nematodes, is used to grasp the female during
copulation.
NEMATODES (ROUNDWORMS)
Nematodes are usually bisexual. Males are
usually smaller than females, have a curved
posterior end, and possess (in some species)
copulatory structures, such as spicules (usually
two), a bursa, or both. The males have one or (in
a few cases) two testes, which lie at the free
end of a convoluted or recurved tube leading into
a seminal vesicle and eventually into the cloaca.
NEMATODES (ROUNDWORMS)
The developmental process in nematodes
involves egg, larval, and adult stages. Each of
four larval stages is followed by a molt in which
the cuticle is shed. The larvae are called second-
stage larvae after the first molt, and so on. The
nematode formed at the fifth stage is the adult.
NEMATODES (ROUNDWORMS)
QUIZinification