Table of Contents

May 2011 ● Volume 12, Number 3

Illustration by Erin Moore

Reviews
143 Clinical Trials of Vascular Disrupting Agents in Advanced Non–Small-Cell Lung Cancer
Mark J. McKeage

148 Scar Carcinoma of the Lung: A Historical Perspective

Ravi K. Bobba, Jason Scott Holly, Tim Loy, Michael C. Perry

Original Studies
155 Docetaxel Vs. Vinorelbine in Elderly Patients With Advanced Non–Small-Cell Lung Cancer: A Hellenic
Oncology Research Group Randomized Phase III Study
Athanasios Karampeazis, Lambros Vamvakas, Athina Agelidou, Nikolaos Kentepozidis, Kyriakos Chainis,
Vassilis Chandrinos, Nikolaos Vardakis, Athanasios G. Pallis, Charalambos Christophyllakis,
Vassilis Georgoulias

161 A Phase II Study of Carboplatin and Irinotecan in Extensive Stage Small-Cell Lung Cancer
Leora Horn, Zhiguo Zhao, Alan Sandler, David Johnson, Yu Shyr, Steven Wolff, Russell F. DeVore,
Janessa Laskin

166 The Role of NF-E2-Related Factor 2 in Predicting Chemoresistance and Prognosis in Advanced
Non–Small-Cell Lung Cancer
Haihong Yang, Wei Wang, Yalei Zhang, Jin Zhao, Enyun Lin, Jing Gao, Jianxing He

172 Serum Tumor Markers CEA, CYFRA21-1, and CA-125 Are Associated With Worse Prognosis In
Advanced Non–Small-Cell Lung Cancer (NSCLC)
Susana Cedrés, Isaac Nuñez, Marina Longo, Pablo Martinez, Eva Checa, Davis Torrejón, Enriqueta Felip
180 Frameless Image-Guided Stereotactic Body Radiation Therapy for Lung Tumors with 4-Dimensional
Computed Tomography or 4-Dimensional Positron Emission Tomography/Computed Tomography
Sameer K. Nath, Ajay P. Sandhu, Lindsay Jensen, Daniel Kim, Anjali Bharne, Polly D. Nobiensky,
Joshua D. Lawson, Mark M. Fuster, Lyudmilla Bazhenova, William Y. Song, Arno J. Mundt

187 A Phase II Study of Higher Dose Weekly Topotecan in Relapsed Small-Cell Lung Cancer
David R. Spigel, F. Anthony Greco, Howard A. Burris III, Dianna L. Shipley, Bobby L. Clark,
Robert C. Whorf, Edward R. Arrowsmith, John D. Hainsworth

192 Clinical Value of Assaying Tumor Supplied Group of Factor/Tumor Specific Growth Factor in Patients
With Solitary Pulmonary Nodule
Bo Deng, Qun-You Tan, Xiao-Qing Fan, Yao-Guang Jiang, Yun-Ping Zhao, Jing-Hai Zhou, Yong-Gang Liang,
Ru-Wen Wang

197 Prognostic Implications of Parathyroid Hormone-Related Protein in Males and Females With
Non–Small-Cell Lung Cancer
Philippe R. Montgrain, Leonard J. Deftos, Douglas Arenberg, Ann Tipps, Rick Quintana, Shannon Carskadon,
Randolph H. Hastings