Can Diseases Be Prevented ??

- Devam , Dhyan
Pathogenic Microorganisms
These organisms
cause harm to
humans in one or
the other way.
Monkeypox
● It is a virus similar to smallpox but comparatively less deadly.
● It is not yet known how was this virus originated, but scientists suspect African
rodents and monkeys might have transmitted the disease to humans.
● Symptoms of Monkeypox: headache and body aches, rashes, fatigue and
swollen lymph nodes.
● How does it spread?
● Human to Human transition:
● Occurs through direct contact with body fluids, indirect contact with
contaminated clothing or bedding.
● Animal to Human transition: A bite or scratch
● Is there any cure?
● Currently there isn’t any vaccine or cure for the Monkeypox, but antiviral
medications used for smallpox may help in reducing the infection.
Monkeypox
 ● Monkeypox was first identified
in a 9-year-old boy in
Democratic Republic of Congo.
● A monkeypox outbreak could
Fun Facts be expected as cases of
Monkeypox have raised in
Africa and European and UAE
travellers are suspected to have
it. In Kerala and Himachal
Pradesh UAE travellers had
symptoms of Monkeypox
STAT3 Dominant Negative Virus
● STAT3DN also know as hyper-IgE syndrome ( AD-HIES ) or Job’s Syndrome
● Symptoms :
○ High levels of immunoglobulin E ( IgE )
○ Recurrent skin and lung infections
○ Recurrent bone fractures
○ Unusually flexible joints
○ Inflamed skin
● STAT3DN occurs from mutations in the gene that encodes a signaling protein called
STAT3
● Effective treatments for this are continuous antibiotics, antifungals as needed and
carefully monitoring for infection which can be severe even when symptoms don’t
appear
● Antibody replacement therapy also works and antiseptics are applied to improve
eczema and skin infections
STAT3 Dominant Negative Virus
Thanks
Be alert I am everywhere

— Mr. Pathogen