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CLINICAL

The injection resin technique: a novel concept


for developing esthetic restorations

Douglas A. Terry,1 John M. Powers2 and Markus B. Blatz3

The concept of using an injectable molding technique to manufacture various parts has
been around for over a century.1,2 The first injection-molding machine was developed
and patented by John and Isaiah Hyatt in 1872 for producing celluloid plastic parts.1,3
The next half-century saw the adoption of this process for the manufacture of items such
1
Douglas A. Terry, DDS
Private Practice, Houston, Texas; as collar stays, buttons, and hair combs.3 Over the course of its development, injection
Adjunct Professor, Department of molding has been used by designers and engineers for myriad applications with a host
Restorative Sciences, University of materials, including glass, metals, confections, elastomers, and thermoplastic and
of Alabama at Birmingham,
Birmingham, Alabama, USA. thermosetting polymers, to fabricate a variety of complex shapes with high dimensional
precision. It has been used in a variety of manufacturing industries, including aerospace,
2
John M. Powers, PhD automotive, jewelry, avionics, biomedical, orthodontics, pharmaceutical, scientific,
Clinical Professor of Oral
electronic, and computer technology. In dentistry, this technique has been used in the
Biomaterials, Department
of Restorative Dentistry and laboratory fabrication of prosthetic appliances such as complete dentures, partial
Prosthodontics, University of Texas dentures, laboratory-processed acrylic and composite provisional restorations, and
Health Science Center at Houston, ceramic restorations. 1,2
School of Dentistry, Houston, Texas,
USA. Continued developments in adhesive technologies, the design of resin composite
formulations, and innovative application techniques have revolutionized the delivery
3
Markus B. Blatz, DMD, PhD of minimally invasive direct resin composite restorations while improving the practice
Professor and Chair, Department of
Preventive and Restorative Sciences, of dentistry. In some cases, complicated layering techniques are required that are
University of Pennsylvania School dependent on the clinician’s skill and artistic ability. The injectable resin composite
of Dental Medicine, Philadelphia, technique provides a simplified, precise, and predictable method for developing natural
Pennsylvania, USA.
esthetic composite restorations while reducing chair time. Although not a panacea to all
Correspondence: restorative challenges, this technique provides the patient and clinician with an alternative
Dr Douglas A. Terry, approach to various clinical situations. This technique is a unique and novel indirect/
Institute of Esthetic & Restorative direct process of predictably translating a diagnostic wax-up or the anatomical form of
Dentistry, 12050 Beamer Road,
Houston, TX 77089. the natural dentition of a preexisting diagnostic model into composite restorations. There
Email: dterry@dentalinstitute.com are myriad applications for this technique using a highly filled flowable (injectable) resin

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CLINICAL

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Figure 1: Preoperative facial view of the maxillary anterior Figure 2: Development of a diagnostic wax-up that established
segment of a 63-year-old who presented with incisal wear and new parameters (ie, esthetic, functional) for the final restorations.
fracture on the maxillary anterior teeth. The patient requested a
conservative esthetic enhancement without orthodontic treatment.
Clinical evaluation revealed multiple diastemas and cervical
corrosion on the central incisors from lemon sucking.

disocclusion) prior to definitive restoration.1-3 Furthermore,


this noninvasive technique is an integral tool for enhancing
communication between the patient and the restorative team
during treatment planning.1,2,4
Developing transitional resin composite restorations using
the injectable technique is an excellent method for increasing
the patient’s understanding of the planned clinical procedure
and anticipated final result.7 Transitional composite
prototypes establish parameters for occlusal function,8 tooth
position and alignment,9 restoration shape and physiologic
3 contour,10 restorative material color and texture, lip profile,
phonetics, incisal edge position, and gingival orientation.
Figure 3: A clear polyvinyl siloxane matrix was fabricated to This process also eliminates confusion and misunderstanding
replicate the diagnostic wax-up. between the patient and the restorative team during the
treatment-planning stage.7 It can reduce the potential for
patient dissatisfaction and litigation because the process
composite, including emergency repair of fractured teeth is reversible, can be performed without preparation, and
and restorations; modification and repair of prototypes and allows the patient to accept the visual and functional result
provisional restorations, composite restorations (Class III,IV, before the definitive restorations are fabricated. In addition,
and V; veneers), and pediatric composite crowns; resurfacing this simple procedure helps to regulate the dimensions of
of occlusal wear on posterior composite restorations; the preparation design, ensures uniform spatial parameters
establishment of incisal edge length prior to esthetic crown for the restorative material, and increases the potential for
lengthening; orthodontic space management; development a more conservative preparation design.4 This injectable
of composite prototypes for copy milling; fabrication of an technique can also be used in the development and
implant-supported composite provisional restoration; and management of soft tissue profiles and in the design of the
repair of fractured or missing denture teeth.1,4-6 In addition, this definitive restoration.11-14 The clinician and technician can use
technique can be used to establish vertical dimension and this technique as a guide for developing a preapproved
to alter occlusal schemes (anterior guidance and posterior functional and esthetic definitive restoration.15 In some cases,

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4 5

Figure 4: Upon completion of the adhesive protocol, the clear silicone matrix was placed over the arch and an opacious shade A2
flowable resin composite (G-aenial Universal Flo, GC America) was initially injected through a small opening above each tooth,
followed by mixing with a shade B1 flowable resin composite (inverse injection layering technique). The resin composite was cured
through the clear resin matrix for 40 seconds.

Figure 5: Completed composite veneer restorations with optimal anatomical form. The inverse injection layering technique allowed the
establishment of harmonious proportions of the transitional restorations and the surrounding biologic framework.

these transitional restorations can be worn for months or mechanical and physical properties. Earlier studies by Gallo
even years during long-term interdisciplinary rehabilitation.2,4 et al. 24 on specific flowable resin composites suggested that
However, this material technique should not be utilized as a these materials should be limited to small-and moderate-
final material for full-mouth rehabilitation. sized restorations having isthmus widths of one-quarter or
In certain clinical situations, this technique can be less of the intercuspal distance.31 However, Torres et al. 38
performed intraorally without anesthesia. A clear polyvinyl reported that, after 2 years of clinical service, no significant
siloxane (PVS) impression material is used to replicate the differences were found between Class II restorations restored
diagnostic wax-up or the anatomical form of the natural with GrandioSO (VOCO) conventional nanocomposites
dentition of a preexisting diagnostic model. The clear matrix and those restored with GrandioSO Heavy Flow (VOCO)
can be placed intraorally over the prepared or unprepared flowable hybrid nanocomposites. A study by Karaman et
teeth and used as a transfer vehicle for the flowable resin al. 34 showed similar clinical performance over 24 months
composite to be injected and cured.1,2 (Figs 1 to 5) in restorations of noncarious cervical lesions restored with
the conventional nanocomposites (Grandio, VOCO) and
Empirical Data those restored with the flowable material (Grandio Flow,
Flowable composite materials have been evaluated VOCO). A more recent study by Sumino et al. 37 indicated
in numerous studies16-40 since their inception. Although that the flowable (injectable) materials G-aenial Universal
early flowable formulations demonstrated poor clinical Flo (GC America), G-aenial Flo (GC America) and
performance,1,16 some of the more recent studies34,37,38 Clearfil Majesty Flo (Kuraray Noritake) had significantly
indicate that the clinical performance of specifically tested greater flexural strength and a higher elastic modulus than
next-generation flowable (injectable) resin composites the corresponding conventional nanocomposite materials,
have similar or improved performance to specifically tested Kalore (GC America) and Clearfil Majesty Esthetic (Kuraray
universal resin composites. Attar and others 23 showed that Noritake). The wear and mechanical properties of these
different flowable composites possessed a wide range of specific universal injectable resin composites suggested an

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improved clinical performance compared with that of the tissues improve. With improved mechanical properties
universal composites. Several in vitro studies conducted reported,37 these highly filled formulations are indicated
at GC Research and Development comparing specific for use in anterior and posterior restorative applications.5
flowable material properties of several conventional The clinical applications of these specific next-generation
composites found results similar to those of Sumino et al. universal injectable composites include sealants and
Of the next- generation flowable systems studied, G-aenial preventative resin restorations; emergency repair of
Universal Flo (GC America) and Clearfil Majesty ES Flo fractured teeth and restorations; fabrication, modification
(Kuraray Noritake) showed superior gloss retention and and repair of composite prototypes and provisional
similar wear resistance to the conventional nanocomposites restorations4; anterior and posterior composite restorations;
tested, which included Filtek Supreme Ultra (3M ESPE), composite tooth splinting;51 and intraoral repair of fractured
Herculite Ultra (Kerr), Clearfil Majesty ES-2 (Kuraray ceramic and composite restorations.51 In addition, these
Noritake) and G-aenial Sculpt (GC America). composites can be used to repair denture teeth,51 establish
According to these studies, these recently developed vertical dimension, alter occlusal schemes before definitive
specific nanohybrid flowable resin (or universal injectable) restoration,5 manage spatial parameters during orthodontic
composite systems (ie, Clearfil Majesty ES Flow and treatment, eliminate cervical sensitivity,51 resurface occlusal
G-aenial Universal Flo) may possess properties that meet the wear on posterior composite restorations,51 establish incisal
aforementioned mechanical, physical, and optical requisites. edge length before esthetic crown lengthening,51 develop
These properties and the clinical behavior of the biomaterial composite prototypes for copy milling,5 and place pediatric
formulations are contingent upon their structure. New resin composite crowns.6
filler technology allows higher filler loading because of Since the past provides information to improve the future,
the surface treatment of the particles and increase in the the lack of evidence-based research and clinical trial data
distribution of particle sizes. The unique resin filler matrix on flowable biomaterials requires clinicians to evaluate
allows the particles to be situated very closely to each other, the individual mechanical properties of these materials to
and this reduced interparticle spacing and homogeneous determine whether their properties are equal or superior to
dispersion of the particles in the resin matrix increases the those of existing materials. As the clinical performance of
reinforcement and protects the matrix.41-43 In addition, the these next-generation flowable materials has improved over
proprietary chemical treatment of the filler particles allows time, the research data have concurred. Although no direct
proper wettability of the filler surface by the monomer and correlation has been found between a material’s mechanical
thus an improved dispersion and a stable and stronger bond and physical properties and its clinical performance,
between the filler and resin. 8 such a correlation might 9 suggest the potential success of
Studies43-47 clearly indicate the importance that filler a restorative biomaterial for a specific clinical situation.16
content and coupling agents represent in determining However, clinical longevity for restorations developed with
characteristics such as strength and wear resistance. these biomaterials remains to be determined through clinical
Recent studies19,31,48 report that specific flowable (universal studies for each specific clinical application.
injectable) composites have comparable shrinkage stress to Future clinical applications of this novel technique with
conventional composites. According to the manufacturers, these next-generation flowable materials may provide
these next-generation flowable (universal injectable) clinicians and technicians with alternative approaches to
composite formulations are purported to offer mechanical, various clinical situations while allowing them to deliver
physical and esthetic properties similar to or better than improved and predictable dental treatment to their patients.
those of many universal composites.49 The clinical attributes Although the long-term benefits of this novel injectable
of universal flowable composites include easier insertion composite technique remain to be determined, the clinical
and manipulation, improved adaptation to the internal results achieved by the first author in the last 14 years and
cavity wall 50, increased wear resistance, greater elasticity, the aforementioned supporting empirical data for these
color stability, enhanced polishability and retention of next-generation nanocomposite flowables are extremely
polish, and radiopacity similar to enamel. Furthermore, promising. Cases 1 to 5 illustrate some of the many clinical
the clinical indications for these next-generation flowable applications of the injectable resin composite technique
resin composites are increasing as the properties of the using various highly filled formulations of flowable composite
materials and the bond strength of adhesives to dental materials (Figs 6-49).

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Case 1 - Developing the Functional Composite Prototype (Figures 06-14)

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6 7

Figure 6: Preoperative facial view of the maxillary anterior Figure 7: Development of a diagnostic wax-up that establishes
segment of a patient who presented with incisal wear and new parameters (ie, esthetic, functional) for the final restorations.
fracture on the maxillary anterior teeth.

Figure 8: Clear PVS matrix


(Memosil 2, Heraeus Kulzer)
was fabricated to replicate the
diagnostic wax-up.

Figure 9: Flowable composite


resin material (Filtek Supreme
Ultra, 3M ESPE) was injected
through a portal in the matrix,
allowing the material to
completely cover the conditioned
8 9 unprepared enamel surface.

10 11 12

Figures 10, 11, 12: Functional resin composite prototype was completed and inspected in centric relation and protrusive and lateral excursions.

13 14

Figure 13: Functional resin composite prototype established the Figure 14: Facial view at 6-year follow-up.
optimal esthetic parameters for a natural smile.

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Case 2 - Orthodontic Space Management (Figures 15 - 22)

15 16

Figure 15, 16: Preoperative facial view prior to interdisciplinary orthodontic treatment of 11-years-old, who presented with a tooth size
discrepancy on the maxillary anterior segment and caries present on the proximal surfaces of the maxillary lateral incisors. During
orthodontic and restorative evaluation, the patient and parent were explained the significance of achieving specific space requirements
so the orthodontist could position the teeth in the most optimal restorative position that will require a minimal preparation design. It is
important that the appropriate and anticipated result be decided prior to the placement of the orthodontic appliances.

Figure 17: After review with the


patient, parent, and orthodontist, a
diagnostic wax-up was designed
to modify the size and shape of the
maxillary lateral incisors. This wax-
up allowed the restorative team to
evaluate form and function.

17

Figure 19: After the adhesive


protocol is completed, the clear
silicone matrix was placed over the
arch and shade A-1 flowable resin
composite (G-aenial Universal Flo,
GC America) was injected through
a small opening above each tooth.
The resin composite was cured
through the clear resin matrix on the
incisal, facial and lingual aspect for
40 seconds.

18 19

Figure 18: A clear PVS matrix was fabricated to replicate the


diagnostic wax-up. A small opening was made above each
tooth that was to be restored using a needled-shaped finishing
bur (ET Series bur, Brasseler USA).

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Case 2 - Orthodontic Space Management (Figures 15 - 22) contd.

20 21

Figure 20, 21: Completed resin composite restorations with optimal anatomical form for the 11-year-old patient. The composite
injection technique allowed the establishment of harmonious proportions of the transitional restorations and the surrounding biologic
framework. Use of the technique for tooth size discrepancies in the preorthodontic treatment-planning stages simplifies technique the
understanding and management of this restorative dilemma for the patient and the interdisciplinary team.

22

Figure 22: Seven-year follow-up of composite transitional restorations after orthodontic treatment.
Note the minimal wear.

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Case 3 - Restoring Posterior Primary Tooth with an Injectable Composite Crown (Figures 23-30)

23 24

Figure 23, 24: Preoperative occlusal view and radiograph of the primary mandibular second molar of 78-year-old patient with an
existing Class II composite restoration and caries on the distoproximal surface of the tooth. Upon initial consultation with periodontist, the
recommended treatment included an implant and bone graft, and the patient needed to temporarily discontinue his warfarin regimen.
After subsequent medical history and radiographic review and discussion with the patient and periodontist, it was decided that the
injectable resin technique would be a viable alternative treatment for this clinical situation, and the patient agreed.

Figure 26: Adhesive preparation


design included removal of
preexisting defective composite
restoration and carious dentin
and enamel; occlusal reduction
of 1.5 to 2 mm; a circumferential
chamfer 0.3 mm in depth; vertical
proximal, buccal and lingual walls
with slight convergence toward the
occlusal; all internal and external
line angles rounded and cavity
walls smoothed; and unsupported
enamel walls removed to improve
25 26 the path of material flow.

Figure 25: A clear PVS (ExaClear, GC America) matrix was


fabricated to replicate the preoperative diagnostic model, and
an opening was made above the primary mandibular second
molar with a tapered diamond bur (6847, Brasseler USA).

Figure 27: After the injection process was completed,


the matrix was removed and the excess polymerized
resin composite was scoured on the facial, lingual and
interproximal regions with a scalpel blade (#12 BD Bard-
Parker, BD Medical) and removed with a scaler. The occlusal
composite sprue was removed using an 8-fluted pyramidal-
shaped finishing bur (H274, Brasseler USA). 27

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Case 3 - Restoring Posterior Primary Tooth with an Injectable Composite Crown (Figures 23-30) contd.

28 29

Figure 28, 29: Completed primary composite crown. The radiograph reveals ideal proximal contours and contacts with an optimal
marginal integrity at the restorative interface.

30

Figure 30: Clinical follow-up at 18 months. The patient was pleased with the results achieved using this
minimally invasive injection technique.

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Case 4 - The Single Anterior Implant- Immediate Placement Technique (Figures 31-36)

31 32
Figure 31: Facial view of the maxillary anterior segment and Figure 32: Diagnostic wax-up was used for presurgical planning
surrounding tissue of a 28-year-old patient. of the interrelationship between the definitive restoration and the
oral structures and to fabricate the provisional restoration.

33 34

Figure 33: Prefabricated zirconia abutment was placed and Figure 34: A clear silicone matrix was placed over the anterior
secured in position, and the access opening was sealed. Sterilized segment of the maxillary arch, and an opacious shade A3 flowable
Teflon tape was applied on the adjacent teeth to separate the resin composite (G-aenial Universal Flo, GC America) was injected
abutment, and glycerin was applied to the entire surface of the through the small opening above the abutment, followed by a
abutment. translucent A3 flowable resin composite. The resin composite mix
was cured through the clear matrix on the occlusal, buccal, and
lingual aspects for 40 seconds each using an LED curing light.

35 36

Figure 35: Biointegration of the provisional composite crown with Figure 36: Final results after placement of the implant-supported
the peri-implant architecture after 3 months. restoration, revealing optimal hard and soft tissue integration.

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Case 5 - Restoring Anatomical Form and Color (Figures 37-49)

37 38 39

Figure 37: Preoperative facial view of the maxillary anterior segment of a 47-year-old patient who presented with cosmetic concerns
regarding his smile. The patient requested a conservative esthetic enhancement without orthodontic treatment.
Figure 38: A clear polyvinyl siloxane matrix was fabricated to replicate the diagnostic wax-up using a non-perforated tray. A small
opening was made above the lateral incisor that was to be restored using a tapered diamond bur (6847, Brasseler USA). It is important
to clean the internal surfaces with a microbrush to prevent silicone debris incorporating into the flowable material.
Figure 39: After intraenamel preparation and adhesive protocol, the clear silicone matrix was placed over the maxillary arch and an
opacious shade A1 flowable resin composite (G-aenial Universal Flo, GC America) was initially injected through a small opening above
the preparation, followed by mixing with a shade B1 flowable resin composite (injection layering technique). The resin composite was
cured through the clear resin matrix on the incisal, facial, and lingual aspects for 40 seconds, respectively.

40 41 42

Figure 40: The completed resin composite veneer with optimal anatomical form.
Figure 41: At the following appointment, the final restoration was completed by using a composite cutback technique. The artificial
enamel layer of the composite veneer was removed and a corrugated chamfer 0.3 mm in depth was placed around the entire margin
with a long, tapered diamond.
Figure 42: The entire composite surface was etched with 37.5% phosphoric acid (Gel Etchant) for 15 seconds and rinsed for 5 seconds.
Etching of the existing composite cleans the surface.

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43 44

Figure 43: Silane was applied to the composite surface and lightly air dried. An adhesive was
applied to the composite surface and allowed to dwell for 10 seconds, air dried for 5 seconds,
and light cured for 10 seconds using an LED curing light.

45 46

Figure 44-46: Internal characterization was performed according to the appearance of the contralateral tooth and a shade-
mapping diagram. A diluted gray tint (Renamel Creative Color, Cosmedent) was placed along the incisal edge and proximal
regions with a size 08 endodontic file and light cured for 40 seconds. A diluted white tint (Renamel Creative Color, Cosmedent)
was placed along the incisal edge, proximal regions, and in the body with a size 08 endodontic file, and light cured for 40
seconds to stabilize the color and prevent mixing of the tints. A diluted yellow tint (Renamel Creative Color, Cosmedent) was
placed at the cervical and in the incisal third with a size 08 endodontic file, and light cured for 40 seconds. It is the color
variation from these modifiers and tints that creates the three-dimensional effect and the nuances within the incisal edge.

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47 48

Figure 47, 48: A new clear silicone matrix fabricated after the connective tissue surgical procedure was placed over the anterior segment
of the maxillary arch and a clear translucent flowable resin composite (Amaris Flow HT, VOCO) was injected through a small opening
over the artificial dentin layer. The resin composite was cured through the clear resin matrix on the facial and incisal aspect for 40 seconds
each.

49

Figure 49: Three-year follow-up of the composite resin veneer with an ideal
anatomical form and color. Note the nuances in the incisal edge created by using the
composite cutback technique.

Conclusion achieved from this early concept of anatomic stratification


In the past, with the use of conventional resin composites and with successive layers of different restorative composites
the direct bonding technique, the clinician had to combine of varying refractive indexes, shades and opacities. 52-57
the hybrid and the microfill because of the inequities of This development of the polychromatic restoration from the
the materials of the time. However, polychromatism was inequities of the different composite resin systems (hybrid

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and microfill) stimulated scientists, researchers, clinicians and and Restorative Dentistry: Material Selection and Technique. Houston:
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Reprinted with permission by QDT, Quintessence Publishing:


Terry DA, Powers JM, Blatz MB. The Injection Resin Technique:
A Novel Concept for Developing Esthetic Restorations. QDT
2020:3-17

15 INTERNATIONAL DENTISTRY – AFRICAN EDITION VOL.12, NO.2 APRIL/MAY 2022

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