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lesions like folliculitis to deep-seated abscess and various pyogenic infections like endocarditis,

osteomyelitis, etc. According to Ikegbunam et al. (2013), Staphylococcus aureus is an

opportunistic pathogen affecting both immunocompetent and immunocompromised individuals

frequently resulting in high morbidity and complications which constitutes problems to health.

Chaudhari(2016) stated that medicated soap has germicidal substances in addition to ordinary

soap base in order to increase their antibacterial activity. It therefore, becomes necessary to

investigate the antibacterial activity of some selected medicated soaps (Sanitol Soap, Tetmosol

Soap, Dettol Soap, Tura soap and Safeguard soap) on Staphylococcus aureus isolated from

wound infection.

1.2 Statement of the Problem

The antibacterial soaps can remove 65 to 85% bacteria from human skin (Osborne and Grube,

2012). Although fats and oils are general ingredients of soaps but some detergent additives

enhance the antibacterial activities of soaps (Friedman and Wolf, 2016). Transient bacteria are

deposited on the skin surface from environmental sources and cause skin infections. Examples of

such bacteria are Pseudomonas aeruginosa (Fluit et al., 2011) and Staphylococcus aureus (Higaki

et al., 2010). The importance of hand washing is very crucial when it is associated to health care

workers because of possible cross contaminating of bacteria that may be pathogenic or

opportunistic (Richards et al, 2019). Hand hygiene and prevention of infection

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Poole, K (2012). Mechanisms of bacterial bioade and antibiotic resistance. Journal of Applied

Microbiology. 92: 555-564.

Reference

Richards, M.J, Edwards,J.E., Culver, D.H and Gaynes, R.P (2019) Nosocomial infections in

medical intensive care units in the United States. National Nosocomial infections surveillance

system. Critical Care Medicine journal 27. 887-892.Schommer NN, Gallo RL. Structure and

function of the human skin microbiome. Trends Microbiol. 2013;21(12):660-668. Sfriso R, Egert

M, Gempeler M, Vogeli R, Campiche R. Revealing the secret life of skin with the microbiome

you never walk alone. Int J Cosmet Sci. 2019;n/a. https://doi.org/10.1111/ics. 12594. doi:

10.1111/ics. 12594. Simonne, A., Hand hygiene and hand sanitizers, in Department of Family,

Youth and Community Sciences, Institute of Food and Agricultural Sciences (IFAS).2016,

University of Florida. Staphylococcus aureus from clinical samples. Journal of Biological

Science. 2(7). Tambekar D, et al. Prevention of transmission of infectious disease: studies on

hand hygiene in health-care among students. Cont J Biomed Sci. 2007;1: 6-10. Tambekar DH,

Shirsat SD. Hand washing: a cornerstone to prevent the transmission of Diarrhoeal infection.

Asian J Med Sci. 2019;1(3): 100-3. Tong, S.Y., Davis, J.S., Eichenberger, E., Holland, T.L.,

Fowler, V.G. (2015).

Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and

management. Clinical Microbiology Reviews. 28 (3): 603-661.White, D.G and McDermolt, P.F

((2021). Biocides, drug resistance and microbialevolution; Current Opinion in Microbiology; 4:

313-317.Wolf R, et.al, Soaps, shampoos, and detergents. Clin Dermatol. 2021.

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