Lary Spray FAQs

Indications:

Throat Congestion:
A build-up of mucus in an airway or cavity of the body causes Throat Congestion.

Throat Irritation:
Is pain, scratchiness or irritation of the throat that often worsens when you swallow. The most
common cause of a sore throat (pharyngitis) is a viral infection, such as a cold or the flu.

Pharyngitis:
Is the inflammation of the mucous membranes of the oropharynx. In most cases, it is caused by
an infection, either bacterial or viral.

Tonsillitis:
Is inflammation of the tonsils, two oval-shaped pads of tissue at the back of the throat — one
tonsil on each side. Signs and symptoms of tonsillitis include swollen tonsils, sore throat, difficulty
swallowing and tender lymph nodes on the sides of the neck.

Post-Operative Sore Throat:

Sore throat is a common postoperative complaint, occurring most often following tracheal
intubation. Factors such as tracheal-tube size and cuff design have been shown to be important causative
factors.

Mouth Ulcer:
Mouth ulcers are painful sores that appear in the mouth. Although they're uncomfortable, they're
usually harmless and most clear up by themselves within a week or two.

Periodontitis:
Periodontitis is a disease of the tissue surrounding the tooth structure. The disease is affected by
both local as well as systemic etiological factors. Periodontitis is one of the most common diseases
associated with the oral cavity.
Inflammation of the tissue around the teeth, often causing shrinkage of the gums and loosening of the
teeth.

Gingivitis:
Gingivitis is a common and mild form of gum disease (periodontal disease) that causes irritation,
redness and swelling (inflammation) of your gingiva, the part of your gum around the base of your teeth.
It's important to take gingivitis seriously and treat it promptly. Gingivitis can lead to much more serious
gum disease called periodontitis and tooth loss.

Mucositis:
Mucositis is when your mouth or gut is sore and inflamed. It's a common side effect of
chemotherapy and radiotherapy for cancer. Although mucositis is usually painful, it can be treated.

Denture Stomatitis:
Denture stomatitis pertains to a number of pathological symptoms in the oral cavity caused by
wearing acrylic dentures. Etiological factors include: mucosal trauma, fungal infection and accumulation
of denture plaque.
 Lary Spray FAQs
Post Oral Surgery:
You may have some pain, bleeding, or swelling afterward, depending on the procedure. You may
get medicine for pain. The pain should improve steadily after the surgery. Dental surgery includes
procedures such as tooth extractions, root canals, gum surgery, and dental implants.

What are antiseptics?

 Antiseptics are antimicrobial substances that are applied to living tissue/skin to reduce the
possibility of infection.
 Antiseptics kill or inhibit the growth of microorganisms on the external surfaces or mucous
membranes of the body.

What is Local Anaesthetic?

Anaesthetic:
 Loss of sensation
 Local anaesthetic causes a reversible and complete loss of pain sensation (nociception) to a
specific area of your body without loss of consciousness
 These drugs works by blocking the nerves from the affected part of the body so that signals can't
reach to the brain
Lidocaine
 Lidocaine, a local anesthetic, is used to treat the pain of a sore or irritated mouth and throat
 Lidocaine is used topically to relieve pain from inflammations of mucous membranes such as
throat.

Chlorhexidine
 Antiseptic with antibacterial, antifungal and some antiviral activity.
 Chlorhexidine is a chemical antiseptic which kills (bactericidal) both gram-positive and gram-
negative microbes.
 It is also bacteriostatic.
 Chlorhexidine is active against Gram-positive and Gram-negative organisms, facultative
anaerobes, aerobes, and yeasts.
 Lary Spray FAQs
Q. Is Chlorhexidine is more effective than Povidone Iodine ?

Ans:
As per published evidence in J Indian Soc Pedod Prev Dent. 2008 Jan; 26 Suppl 1:S14-8
Chlorhexidine proved to be more effective than Povidone Iodine in reducing salivary bacterial counts.

If you require more update will provide you study folder.

Study Article:

The effect of chlorhexidine mouthwash on bacterial microcolonies in recurrent tonsillitis

(James Johnston1, Kristi Biswas1, Sharon Waldvogel-Thurlow1, Fiona J. Radcliff2, Murali Mahadevan1, Richard
G. Douglas1)

Results:
There were significantly fewer bacterial microcolonies observed in the tonsils that were exposed to chlorhexidine
mouthwash when compared to the 0.9% sodium chloride group (P<0.05). There were also fewer bacterial
microcolonies present in tonsils exposed to chlorhexidine mouthwash when compared to unexposed tonsils
(P<0.05). There was no difference in the number of microcolonies in the unexposed tonsils from participants in the
chlorhexidine group when compared with the saline group (P=0.68).

Conclusions:
Chlorhexidine mouthwash appears to be effective in significantly reducing the number of bacterial microcolonies
that exist in the crypts of these participants with RT.

Q. Can Chlorhexidine gluconate reduce the risk of LRTI?

Ans:
As per published evidence in J Hosp Infect. 2007 Jul;66(3):207-16 A meta-analysis of seven randomized
controlled trial, reported reduction in relative risk of LRTI in Chlorohexidine (CHX) group

Conclusion:

Oral Chlorhexidine gluconate may reduce the risk of LRTI; therefore, can be preferred as preventive agent
for any future development of LRTI.
 Lary Spray FAQs

Q. Role of chlorhexidine in cancer mucositis in children ?

Ans:
As per published evidence in J Pediatr Oncol Nurs. 2011 Sep-Oct;28(5):295-9

 Oral mucositis, also referred to as stomatitis, is defined as an injury of the oral mucosa found most
commonly in cancer patients and can be the result of either irradiation or chemotherapy.

 A statistically significant reduction was seen in ulcerative lesions and severity of mucositis in children on
the chlorhexidine.

 100% compliance in children receiving prophylactic 0.2% chlorhexidine rinses 4 times a day have been
reported in clinical studies.

 Various studies in children concludes that “Chlorhexidine may play a part in reducing oral mucosal
damage during chemotherapy for children receiving chemotherapy, possibly due to a reduction in oral
microflora and plaque.

Lidocaine in sore throat:

As per published evidence in Cochrane Database Syst Rev. 2015 Jul 14;2015(7):CD004081.

Aim:

To evaluate the efficacy and any harm caused by topical and systemic lidocaine used prophylactically to prevent
postoperative sore throat in adults.

Studies included: 19 studies involving 1940 participants

Result:

 Topical and systemic lidocaine therapy appeared to reduce the risk of postoperative sore throat
 The severity of sore throat as measured on a visual-analogue scale (VAS) was reduced by lidocaine therapy
 The adverse effects of lidocaine were not reported in these studies, though toxicity is generally rare.
 Lary Spray FAQs

Q. Pain reduction with lidocaine in sore throat:

Ans:
As per published evidence in Arzneimittelforschung.2007;57(11):689-97. doi: 10.1055/s-0031-1296669.

A clinical study in 240 patients with acute pharyngitis reported that lidocaine 8 mg sore throat lozenges to be a
favorable option in the treatment of pain symptoms of an acute sore throat.

Result:

The results of the trial emphasize lidocaine 8 mg sore throat lozenges to be a favorable option in the treatment of
pain symptoms of an acute sore throat.

Q. Does Laryspray cure cough & cold?

Yes, Laryspray is beneficial in cough and cold. Lidocaine has been evaluated in various trials as a spray to suppress
cough. It has also been used to reduce the incidence of postoperative sore throat, cough, and hoarseness of voice. It
produces rapid cough suppression via bronchial anesthesia. Dry cough is commonly seen in patients with running
nose due to post-nasal drip. Lidocaine by its anaesthetic action, suppresses the irritation and cough.

Q. Can Laryspray be used by persons who are also suffering from other ailments such as Diabetics, Heart
problems, Cancer etc?

Yes, Laryspray can be used by diabetic patients since it is sugar-free.It can also be used by cancer patients & those
with heart problems but it is advisable for the heart patients to consult your physician before the use of any kind of
OTC medication including Laryspray.
 Lary Spray FAQs

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