Analysis Type: PANTHER Overrepresentation Test (Released 20221013)

Annotation Version and Release Date: GO Ontology database DOI:

10.5281/zenodo.7942786 Released 2023-05-10
Analyzed List: upload_1 (Homo sapiens)
Reference List: Homo sapiens (all genes in database)
Test Type: FISHER
Correction: FDR
GO molecular function complete Homo sapiens - REFLIST (20589) upload_1
(32) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment)
upload_1 (raw P-value) upload_1 (FDR)
ubiquitin ligase complex scaffold activity (GO:0160072) 2 2 .00 +
> 100 1.40E-05 7.85E-03
Wnt receptor activity (GO:0042813) 16 3 .02 + > 100 3.23E-06
4.09E-03
Notch binding (GO:0005112) 26 4 .04 + 98.99 1.27E-07 6.43E-04
frizzled binding (GO:0005109) 40 4 .06 + 64.34 6.21E-07 1.05E-03
Wnt-protein binding (GO:0017147) 32 3 .05 + 60.32 2.15E-05 9.88E-
03
transcription coactivator activity (GO:0003713) 288 5 .45 + 11.17 8.23E-
05 2.97E-02
RNA polymerase II-specific DNA-binding transcription factor binding (GO:0061629)
353 6 .55 + 10.94 1.65E-05 8.35E-03
G protein-coupled receptor binding (GO:0001664) 298 5 .46 + 10.80 9.64E-
05 3.25E-02
ubiquitin protein ligase binding (GO:0031625) 307 5 .48 + 10.48 1.11E-
04 3.29E-02
ubiquitin-like protein ligase binding (GO:0044389) 326 5 .51 + 9.87
1.46E-04 4.10E-02
DNA-binding transcription factor binding (GO:0140297) 487 7 .76 + 9.25
8.69E-06 7.32E-03
transcription coregulator activity (GO:0003712) 512 7 .80 + 8.80 1.20E-
05 7.57E-03
protein domain specific binding (GO:0019904) 668 8 1.04 + 7.71 6.70E-
06 6.78E-03
transcription factor binding (GO:0008134) 610 7 .95 + 7.38 3.64E-05
1.53E-02
molecular function activator activity (GO:0140677) 1215 10 1.89 + 5.30
1.02E-05 7.38E-03
enzyme binding (GO:0019899) 2114 15 3.29 + 4.57 1.57E-07 3.98E-04
signaling receptor binding (GO:0005102) 1518 10 2.36 + 4.24 6.89E-05
2.68E-02
transcription regulator activity (GO:0140110) 1932 11 3.00 + 3.66 1.00E-
04 3.17E-02