Dr. B.

Lal Institute of Biotechnology

Pre-University Examination 2020
B.Sc. Biotechnology Part - III
Subject- Medical Biotechnology (Paper Code- BT-801)

Time – 3 hrs. Maximum Marks – 50

Attempt five questions in all, including Question No. 1 which is compulsory

Q.1. Compulsory question 10

i. What are chromosomal abberations?

ii. Define herd immunity.
iii. Differentiate between prevalence & incidence of an infectious disease.
iv. List 2 virulence factors of Clostridium tetani.
v. What feature of Mycobacterium makes it acid fast?
vi. Define chickenpox. Name the causative agent of chickenpox.
vii. What does fungal dimorphism mean? Name any 2 dimorphic fungi.
viii. Explain superficial mycosis. Name any 2 examples and the disease that they cause.
ix. Explain bcr/abl.
x. What are CD4 lymphocytes? What is the relation between these cells and HIV?

Section A
Q.2. Explain in detail the antimicrobial compounds and their modes of action. 10
OR
Write short notes on any two:- 5+5= 10
i. Chromosomal aberrations
ii. Gene therapy
iii. Modes of transmission of pathogens

Section B
Q. 3. Give an account on pathogenicity, diagnosis, treatment and prevention of typhoid. 10
OR
Write short notes on:- 5+5= 10
i. Whooping Cough
ii. Diphtheria

Section C
Q. 4. Give a general account of fungal diseases. 10
OR
Write short notes on any two:- 5+5= 10
i. AIDS
ii. Leishmania
iii. Chickenpox

Section D
Q. 5. Write short notes on:- 5+5= 10
i. Immunotoxins
ii. Genomic & cDNA Microarrays
OR
Explain in detail the stem cell based drug discovery and its therapeutic applications 10