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Disease Process:
Pathophysiology (Definition/etiology chronicity & progress)
Preeclampsia – is a common disorder that particularly affects first pregnancies. A type of hypertensive disorder that occurs
during pregnancy (after 20 weeks of gestation) it is also important to note that this condition can present during postpartum
period. Severe preeclampsia can cause seizures which can lead to death and when that happens, it is called “eclampsia”
which means “a convulsive state.” It’s poorly developed uterine placental spiral arterioles (which decrease uteroplacental
blood flow during late pregnancy), a genetic abnormality on chromosome 13, immunologic abnormalities, and placental
ischemia or infarction. The clinical presentation is highly variable but hypertension and proteinuria are usually seen.
Preeclampsia is primarily a disease of the placenta as it may be encountered in molar pregnancies. One of the most accepted
theories in preeclampsia revolves around abnormal placentation.