TAKORADI TECHNICAL UNIVERSITY * FACULTY OF APPLIED SCIENCES INDUSTRIAL & HEALTH SCIENCES DEPARTMENT. MID SEMESTER I EXAMINATION, 2021/2022. ie BIOCHEMISTRY I ReTC0,/ MEG, orcas LABTECH: LEVEL 100) Course Code: MLS 103 Time Allowed: 1 HOUR SECTION A [Answer ALL Questions) 1, Simplest aldehyde and ketone contain, respectively, how many carbon atoms? Aland! (B) Land3 Ce.Qand2.D, 2and3 2.The TUPAC name for the formula CHC H,CHOHCH=CHy is ‘ AS “S-hexene-3-0l.: © Jehexene-3-ol 3s The Teagent Which would if. Ag(NHs)"" B, KMn0," ©. Br inCCl hen a solid organic compound is recrystallized, the cold filtrate from 'the cooled mixture is (A) . saturated with the compound. «.. B. an.unsaturated solution of the compound. entirely free of the compound, D. pure solvent, 5. Which of the amines listed below. would have the lowest boiling point? ‘A. | CHsCH;CH2NFR - |B, CHsCH:NHCHS": €) (CH;)sN (CH) CNEL 6. What are the repeating Tunits of nucleic acids? A, phosphate molecules ® nucleotides C. bases Dy nan molecules 7, Chromosomes. moaarureanas are generally taken during. A. Interphase B: Prophase ‘C.Anaphase (DB Non-of these 8, The most comtion form of severely affected people who are having more than 1000 repeats of the CTE triplet ae ealled eas ue F ‘ : @ Myotoni dysuophy’ B:FraglleXyndomeC. Retinoblastoma. D. Anaphase9. Proteins are made of amino acids linked together by specific bonds called A)Peptide bonds B. Nitrogen bonds C. Hydrogen bonds D, Hydrogen & Nitrogen bon 10, Cancer cells are ....s.ssssseeseeee A. Unlimited number of cell divisions B. Growth without external signals C. Avoidance of cell death @ Allof the above 11. The enzyme which builds a mRNA strand complimentary oe transcription unit is A.DNA polymerase (B)RNA polymerase C.Helicase ‘DD. DNA ligase 12. A gene is a section of DNA that codes for a protein, this unique sequence of bases will codt for the production of a unique protein is: @ Exon B. Intron C, Regulatory sequence D. Non-of these _13. Changes in the nucleotide sequence of DNA. .which-aren’t passed-to offspring occurim ~~ ~ A. Eggs & sperm cells Non-sexual cells C. Diploid and haploid cells D. All of the abox 14. Those mutations that occur by environmental damage or mistakes during DNA replications are @ Acquired mutations B, Inherited mutations C.AandB D. Non-of them 15, Proto-oncogene in normal cells .. (Code for proteins involved in the stimulus of cell division B., Suppresses progression through the cell cycle in response to DNA damage C. Initiates apoptosis D, Non-of the above 16. During cell division there are three types of check points one of them (M checkpoint) to ensure ® ; {A) Chromosomes are attached to the spindle B, Complete DNA replicationC, DNA not damage or ‘broken D. All of the above 17, Those cancers that derived from ectoderm or endoderm of epithelial cell are called @ Carcinoma B, Sarcoma C, Leukaemia D, Myeloid E. Non-of these 18, ____ js a genetic changes that occurin more than 1 pereent of the population @ Polymorphisms: B. Monotheism C. Frameshift mutation. D, Ditheism 19, A heritable feature is a and may have two or more variants called, A. trait/characteristics ® character/traits’ .-C. charactor/factors: D. trait/factors 20, Histone four (Hy) consists of 102 amino acids and it has A. Negative charge Positive charge ©. Neutral D. Non-of these 2. Ae _ made inside the mucleus ofa cell, associates with ‘proteins to form! ribosomes. Ajm@RNA — (B)rRNA tRNA D. All ofthe above. 22, Proteins that assist the binding of RNA eal ere the promoter region on DNA iri ¥ are called sirens @ Transcription factor. B, SSB Protein: ne Sigma factor D. All of the above: 23. The bie ray ditaton studies conducted bye! were key to the discovery of the structure of DNA A. MeClintok @ Franklin ©" Meselséin and Stahl D. Chargaff, 24. Which ofthe following is not needed for DNA transcription? ; @Ribosomes —_" B, Nucleotides CDNA D. Engymes 25. All of the cells selthin an individual are genetically identical, A. True @ Fatse 26. The triplet code of CAT in DNA. ke Tepresented ds in mRNA and in tRNA. @ aaa, cat _B.CAT, cat ¢. GUA, CAU D. ork :27. Which of the following may contribute to causing cancer? ‘A. a mutation in a gene that slows the cell cycle B. faulty DNA repair C. loss of control over telomere length (Dall of the above 28. If you performed a laboratory analysis of DNA, you would find that the amount of adenine is the amount of thymine, : Acmuch greater than B, much less than (C)about the same as Di shows no relationship to ... : 29, Those mutations that arise ir. the absence of known mutagen are known A. Induced mutations B, Fused mutations (C) Spontaneous mutations D. None of the above 30-In addition of histone protein chromatin contains an‘approximately equal mass of a wide