TAREA 1b

Nombre del alumno(a): Eric Eduardo Torres

Hernández

Profesor: Dr. José Miguel Velázquez López

Optimización y procesos de síntesis II

OSETALMIVIR
Satoh, N., Akiba, T., Yokoshima, S., & Fukuyama, T. (2007). A Practical Synthesis of (−)-Oseltamivir.
Angewandte Chemie International Edition, 46(30), 5734–5736. doi:10.1002/anie.200701754
Brinchi, L., Chiavini, L., Goracci, L., Di Profio, P., & Germani, R. (2009). Efficient Hydrolysis of Nitriles
to Amides with Hydroperoxide Anion in Aqueous Surfactant Solutions as Reaction Medium. Letters in
Organic Chemistry, 6(2), 175–179.http://dx.doi.org/10.2174/157017809787582708
 Reactivos Masa E.Q. Moles % Masa Densidad Volumen
Molecular masa requerida Requerido
(g/mol) (Coeficientes Pureza (g) (g/mL) (mL)
Estequimetricos)

A 150.20 1.20 0.0133 100 2.00 --- ---

B 169.61 1 0.0111 100 1.8826 --- ---
C 40 1.40 0.0155 98 0.6213 2.13 0.3

Xiaohe, Z., Yu, Q., Hong, Y., Xiuqing, S., & Rugang, Z. (2010). Research Article: Synthesis, Biological
Evaluation and Molecular Modeling Studies of N-aryl-2-arylthioacetamides as Non-nucleoside HIV-1
Reverse Transcriptase Inhibitors. Chemical Biology & Drug Design, 76(4), 330–339.
https://doi.org/10.1111/j.1747-0285.2010.01017.x
Reactivos Masa Molecular E.Q. Moles % masa Masa Densidad Volumen
(g/mol) Pureza requerida Requerido
(Coeficientes (g) (g/mL) (mL)
Estequimetricos)

ArNO2 123.11 1.00 0.01 98 1.2244 1.2 1 mL

Sn
118.71 3.1250 0.0312 98 0.0318 7.30 0.004
HCl
36.45 15.10 0.151 37 0.4081 1.19 0.34
Synthesis and coordinating properties of ligands designed for modeling of the active site
zinc of liver alcohol dehydrogenase Bernard Kaptein, G. Barf, Richard M. Kellogg, and F.
Van Bolhuis https://doi.org/10.1021/jo00293a039
Novel bis-piperidinium and bis-pyrrolidinium compounds as versatile phase-transfer
catalysts (10-5511HP) Muhammad Jawwad Saif, Jamil Anwar, Munawar Ali Munawar,
Muhammad Kashif and Muhammad Imran Asghar
DOI: https://doi.org/10.3998/ark.5550190.0011.b12