CODIAVELANE™ BG PF

A velvety touch
The promise of a water-soaked caress
#1 - 8882 GB 01 January 2019
CODIAVELANE™ BG PF
Characteristics

INCI name:
CODIAVELANE™ BG PF CODIAVELANE™
Butylene Glycol - Aqua/Water Propylene Glycol - Aqua/Water
Codium Tomentosum Extract Codium Tomentosum Extract

Use level: 2%

Solubility: Water soluble

Form: Limpid to slightly opalescent liquid

Preservatives: None

Claims: Immediate, short & long term hydration -

Deep moisturization - Strengthening the
skin barrier

Formulation easy to use into any type of formulation,

advices: even when cold. Does not impact the final
color or smell.

Approval:

China Compliant: all INCI names are listed on the IECIC list of December 2015 - COSMOS Approved:
raw material approved by ECOCERT GREENLIFE, in conformity with Cosmos standard

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CODIAVELANE™ BG PF
A Velvety Touch
The source of its benefits:
Codium tomentosum
CODIAVELANE™ BG PF
The source of its benefits: Codium tomentosum

SOURCE OF A VELVETY TOUCH...SENSORY PROPERTIES

Codium tomentosum:
seaweed famous for its soft velvety coat

Green velvet color:

Chlorophyll-pigmented seaweed

Velvety touch:
Soft fuzz of tiny hairs
Tomentosum =
Latin: “cushion stuffing, such as wool or feathers"
Botany: "cottony fuzz composed of fine hairs
that conveys an impression of plushness"

"Caress" effect:
A cushion of water held by micro hairs
Spongy bounce:
seaweed composed of 85% water
and jellifying substances

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CODIAVELANE™ BG PF
The source of its benefits: Codium tomentosum

… AND A WATER-SOAKED CARESS

MOISTURIZING POWER
Codium tomentosum: ability to adapt to particularly drying conditions

HIGH TIDE LOW TIDE

6 hr UV
Maintenance of an 85%
hydration rate in the rockpools*
of the Emerald Sea**; cavities
[30]g salt/L with extreme variations in
[45]g salt/L salinity and temperature
MAINTENANCE
85% OF HYDRATION RATE 85% *Small rocky bowls that keep water in this hole at low tide
IN THE SEAWEED
**Exceptional color of the sea bordering northern Brittany

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CODIAVELANE™ BG PF
The source of its benefits: Codium tomentosum

SCARCITY HIGH-QUALITY HARVEST

OF THE In winter only
Presence of an epiphyte that cannot be separated
RESOURCE from the seaweed during sunny periods
Extreme tidal ranges
Seaweed located in the lower foreshore
at a depth of 15 meters; this area is exposed
only during exceptional tides
Dependent on the weather
Regular storms in Brittany d/yr
By hand, with the greatest
RESPECT FOR THE ENVIRONMENT
AND THE RESOURCE

OVER CODIAVELANE™ BG PF: extracted

20 YEARS OF from FRESH SEAWEED
KNOW-HOW Yann QUERREC
CAREFULLY SELECTED
from among 800 seaweeds Production
found in Brittany Deputy Manager

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CODIAVELANE™ BG PF
The Marine Moisturizing Factor (MMF)

> Tested in laboratories, WATER

Codium tomentosum Weight X3
recovers its initial form in 6 min
on contact with water

Our laboratory has identified the molecules responsible for

the moisturizing power of CODIAVELANE™ BG PF

• Sulfated polysaccharides
Intense hygroscopic power
Biomimetic of the GAGs in skin

Codium tomentosum • Glucuronic acid

is rich in: Intense hygroscopic power
Moisturizes in depth
Reinforces the cutaneous barrier
• Minerals
Ensure an osmotic gradient

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CODIAVELANE™ BG PF
A seaweed with multiple properties

> Eaten in certain Asian countries: South Korea, Japan and Indonesia

> Source of energy for a marine animal:

Name: Elysia viridis
Favorite food: Codium
Noted for: kleptoplasty (“stealing” of chloroplasts)
Elysia viridis feeds on Codium’s chloroplasts,

Photos : doris.ffessm © Bruno Glenard

which, by continuing to work, provide energy
for the animal. They also give the slug
its green color, whence its name "viridis" (Latin)

> Ability to heal in just a few seconds:

Codium tomentosum is a so-called "siphoned" seaweed
(made of several cells merged into a single cell).
If it is cut, the plant's survival depends on its ability
to heal rapidly using a polysaccharide gel
that avoids a loss in cytoplasm.

> Antioxidant properties

Identified as a potential source for combating Parkinson's disease
Protective effect of Codium tomentosum alga on SH-SY5Y model of neurotoxicity induced by 6-hydroxydopamine,
Silva J, Alves C and Pedrosa R (2014).
Available on: http://www.frontiersin.org/10.3389/conf.FMARS.2014.02.00071/event_abstract

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CODIAVELANE™ BG PF
The promise
of a water-soaked caress
Proven in vivo
CODIAVELANE™ BG PF
Mechanisms of action

Immediate, Short-term & Long term moisturization

Deep moisturization
MACROSCOPIC
ACTIONS &
86%: more softness A velvety touch
70%: more comfort that can be felt

What happens inside

skin

NMF Glucuronic Acid

Retain water in the skin: Boosts lipid neosynthesis:
MICROSCOPIC ↗ hygroscopy
ACTIONS ↗ ceramides
& ↗ cerebrosides
Capture the surrounding water
into the skin:
↗ hydrophilicity

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CODIAVELANE™ BG PF
Macroscopic actions

SHORT-TERM MOISTURIZATION

Formula tested in vivo

containing CODIAVELANE™ 2%

MONTANOV™ L 3.00%
Caprylic/Capric Triglycerides 10.00%
Propyl Paraben 0.15%
SEPINOV™ EMT 10 1.00%
Aqua/Water Up to 100%
Methyl Paraben 0.20%
Sorbic Acid 0.10%
CODIAVELANE™ 2.00%
Parfum 0.20%
NaOH Up to

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 CODIAVELANE™ BG PF
Macroscopic actions

Non treated zone

SHORT-TERM MOISTURIZATION 1% CODIAVELANETM
2% CODIAVELANETM
IN VIVO test protocol 15 15

Hydration level: % evolution vs. T0

Corneometry 14 14
• 15 volunteers with dry skin (IH<45)
• 2 applications per day on forearm (1% &
2%CODIAVELANETM)
10
8
Autoevaluation 7
• 20 volunteers with dry skin (IH<45)
• 28 days of treatment
• 2 applications per day on forearm of a cream
with 2% CODIAVELANE™
0
After 8H After 24H

CODIAVELANE™ (1% & 2%) helpsfor quick moisturizing action after 8 & 24 hours
CODIAVELANE™ (2%) apporte un effet durable pendant 24H

& 86%: more softness 70%: more comfort

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CODIAVELANE™ BG PF
Macroscopic actions

DEEP, IMMEDIATE & LONG-TERM HYDRATION

Cream formula
with 5% CODIAVELANE™
IN VIVO test protocol
CODIAVELANE™ 5.00%
Glycerin 2.00%
Measurement of the
Sodium Citrate 0.10%
Transient Thermic Transfer
Methyl Paraben 0.20%
• Quantification of the moisturizing effect at different depths
of epidermis Sorbic Acid 0.05%
• Placebo vs. Formula containing 5% CODIAVELANE™ Polyglycerylmetacrylate 5.00%
• 12 volunteers women, 21-46 years old Polyacrylamide Polymer 0.50%
Glycerol Stearate 2.00%
Shea Butter 1.50%
Cetearyloctanoate 1.00%
Cetyl Alcohol 0.50%
Stearyl Alcohol 0.50%
Dimethicone 1.00%
Stearylheptanoate 1.00%
Propyl Paraben 0.15%
Demineralized Water Up to 100%

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CODIAVELANE™ BG PF
Macroscopic actions

DEEP, IMMEDIATE & LONG-TERM HYDRATION

Difference of hydration rate between Formula

IN VIVO test 10 with 5% CODIAVELANETM vs. Placebo
9

Measurement of the 8

Transient Thermic Transfer 7

6

% variation
> Before product application (reference)
> Day 0 - 1h: 1 hour after one application 5

> Day 0 - 3h: 3 hours after the 1st application 4

> Day 8 - t0: 12 hours after a 7 days treatment 3

Superficial layers of the epidermis
(application twice a day) 2
Middle layers of the epidermis
> Day 8 - 1h: 1 hour after another single 1
application, after the Day 8 - t0 measurement
0
Day 0-1h Day 0-3h Day 8-t0 Day 8-1h

CODIAVELANE™ 5% acts in-depth & immediate hydration

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CODIAVELANE™ BG PF
Mechanisms of action

Immediate, Short-term & Long term moisturization

Deep moisturization
MACROSCOPIC
ACTIONS &
86%: more softness A velvety touch
70%: more comfort that can be felt

What happens inside

skin

NMF Glucuronic Acid

Retain water in the skin: Boosts lipid neosynthesis:
MICROSCOPIC ↗ hygroscopy
ACTIONS ↗ ceramides
& ↗ cerebrosides
Capture the surrounding water
into the skin:
↗ hydrophilicity

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CODIAVELANE™ BG PF
Microscopic actions

CODIAVELANE™ BG PF, THE MARINE MOISTURIZING FACTOR...

…THE PROMISE OF DEEP & IMMEDIATE HYDRATION

IN VIVO test

Measurement
of Hygroscopy On D28 (vs. D0):
(Corneometry)
• 40 volunteers with dry skin (IH<45) CODIAVELANE™
• 28 days of treatment Placebo 2%
• 2% CODIAVELANE™
• 2 applications per day on forearm
• Test of sorption-desorption

*p<0.05 (D28 vs. D0)

↗ HYGROSCOPY
CODIAVELANE™ BG PF increases water-fixation potential in the stratum corneum

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CODIAVELANE™ BG PF
Microscopic actions

CODIAVELANE™ BG PF, THE MARINE MOISTURIZING FACTOR...

…THE PROMISE OF DEEP & IMMEDIATE HYDRATION

IN VIVO test
NMF -- NMF ++
Measurement Placebo CODIAVELANE™
of Hydrophilicity D28 2%
(2D imaging) D28
• 40 volunteers with dry skin (IH<45)
• 28 days of treatment
• 2% CODIAVELANE™
• 2 applications per day on forearm CODIAVELANE™ BG PF enhances the spreading
• Test of sorption-desorption
• *p<0.05 (D28 vs. D0)
and the infiltration of surrounding water (daily care, air)

Dry sponge Wet sponge

= Skin NMF -- = Skin NMF ++
VISUALIZATION: Low hydrophilicity High hydrophilicity
↘ spreading ↗ spreading
↘ infiltration ↗ infiltration

#17 - 8882 GB 01 January 2019

CODIAVELANE™ BG PF
Mechanisms of action

Immediate, Short-term & Long term moisturization

Deep moisturization
MACROSCOPIC
ACTIONS &
86%: more softness A velvety touch
70%: more comfort that can be felt

What happens inside

skin

NMF Glucuronic Acid

Retain water in the skin: Boosts lipid neosynthesis:
MICROSCOPIC ↗ hygroscopy
ACTIONS ↗ ceramides
& ↗ cerebrosides
Capture the surrounding water
into the skin:
↗ hydrophilicity

#18 - 8882 GB 01 January 2019

CODIAVELANE™ BG PF
Microscopic actions

CODIAVELANE™ BG PF, THE MARINE MOISTURIZING FACTOR...

…THE PROMISE OF DEEP & IMMEDIATE HYDRATION

IN VITRO test

Epidermal lipids: Histochemical

coloration (Nile Red, microscope 40x)
+
Quantitative measurement
(** liquid scintillation after marking with 14C)

• Treated explants (72H):

• Placebo vs. Formula containing
CODIAVELANE™ BG PF 2%
SC is delipidated, SC is relipidated
lacks coherency and coherent

From 72 hours, CODIAVELANE™ BG PF reinforces the cohesion of the stratum corneum

by boosting the natural synthesis of the lipidic cement.

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CODIAVELANE™ BG PF
Formula
 SKIN CARE
EU07249A
T-Zone Matifier Moisturizer
A Aqua / Water Up to 100%
SEPICONTROL™ A5 4.00%
SEPIMAT™ H10 FW 10.00%
Phenoxyethanol and Ethylhexylglycerin 1.00%
A cream CODIAVELANE™ BG/PF 2.00%
with a powder touch. B SEPINOV™ EMT 10 3.00%
Texture is transformed with Isohexadecane 3.00%
Cyclopentasiloxane and Cyclohexasiloxane 5.00%
SEPIMAT ™ H10 FW! Parfum / Fragrance 0.30%
.
Appearance Off-white & shiny compact cream
pH 5.0
Viscosity 1M at RT 75000 cps Brookfield S4S6
SEPICONTROL™ A5, Viscosity 1M at 45°C 79000 cps Brookfield S4S6
a biomimetic active Viscosity recovery at RT 87000 cps Brookfiels S4S6
enriched with an extract (after 1M at 45°C)

of cinnamon, purifies and Stability* 1M at RT, in cycles -4/+40°C

clears the T-zone..

CODIAVELANE™ BG/PF,
rich-in-sugar marine active, SEPINOV™ EMT 10
gives the fundamental brings a satin-smooth
hydration needed aspect to this cream gel
all along the day. that is perfect for oily and
acne prone skin.
SEPIMAT™ H10 FW
guarantees a real
matifying effect thanks
to its excellent oil
absorption capacity.

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 Thank you
for your attention

wesourcebeauty.com
 Contacts

Nota
The analytical specifications warranted are only those mentioned on the certificate of analysis supplied with each delivery of the product.
Except as set forth above, SEPPIC* makes no warranties, whether express, implied or statutory, as to the product which is the subject of this document. Without limiting the generality of the foregoing,
SEPPIC* makes no warranty of merchantability of the product or of the fitness of the product for any particular purpose. Buyer assumes all risk and liability resulting from the use or sale of the product,
whether singly or in combination with other goods. The information set forth herein is furnished free of charge and is based on technical data that SEPPIC* believes to be reliable. It is intended for use by
persons having technical skill and at their own discretion and risk. Since conditions of use are outside SEPPIC*'s control, SEPPIC* makes no warranties, express or implied, and assumes no liability in
connection with any use of this information. Nothing herein is to be taken as a license to operate under or a recommendation to infringe any patents.

* SEPPIC being:

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