MATERIAL SAFETY DATA SHEET

OF
CELECOXIB AARTI DRUGS LTD

SECTION 1. -------------------------------- CHEMICAL IDENTIFICATION -----------------------------

NAME: CELECOXIB

SECTION 2. ---------------- COMPOSITION / INFORMATION ON INGREDIENTS --------------

2.1 CAS NO: 169590 – 42 – 5

2.2 M.F.: C17 H14F3N3SO2
2.3 PRODUCT GROUP Anti-inflammatory

SECTION 3. ------------------------------ HAZARDS IDENTIFICATION ---------------------------------

3.1 HAZARDOUS POLYMERISATION: Will not occur

3.2 EXPLOSIVE MATERIAL : -NA-
3.3 PYROPHORIC MATERIAL: Nil
3.4 OXIDISER : Nil
3.5 ORGANIC PEROXIDE: -NA-
3.6 CORROSIVE MATERIAL: -NA-
In case of accident or if you feel unwell, seek medical advice immediately.

SECTION 4. -------------------------------FIRST AID MEASURES ------------------------------------------

4.1 EXPOSURE
FIRST AID MEASURES
INHALATION: Move the victim to fresh air, rest allow to cool
down and transport to hospital.
4.2 SKIN CONTACT: Remove contaminated clothes, wash
skin with water and soap and send to
a doctor.

4.3 EYE CONTACT: First rinse with plenty of water, then

Transport to hospital, if necessary.
4.4 INGESTION: Rinse mouth, give plenty of water to
drink, induce vomiting, and transport to
hospital immediately.
4.5 ANTIDOTES / DOSAGES: None known. Treat symptomaticaly.
SECTION 5. --------------------------------FIRE FIGHTING MEASURES---------------------------------

Extinguishing Media:Carbon dioxide, chemical powder or appropriate foam. Water spray

.Unusual fire and explosion hazards:
Emits toxic fumes under fire conditions
Special fire fighting procedures:
Wear self-contained breathing apparatus and
protective clothing to prevent contact with the
skin and eyes

SECTION 6. ----------------------- ACCIDENTAL RELEASE MEASURES -----------------------------

Ensuring personal safety, mark out contaminated area with signs and prevent unauthorised access.
Turn leaking containers up to prevent further Evaculate area. Wear self-contained breathing apparatus,
rubber boots & heavy rubber gloves. Sweep-up/absorb in suitable material, place in a container and
hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pick-up complete

SECTION 7. ----------------------- HANDLING AND STORAGE ------------------------------------------

7.1 HANDLING AND STORAGE Preserve in well-closed containers and Store at

PRECAUTIONS: Room Temperature. No open flame and no
smoking in the storage area. Prevent dispersion of
dust. Provide
local exhaust or breathing protection, where dust
concentration is high. Do not eat, drink of smoke
during work.
Avoid direct contact with the substance.

SECTION 8. ---------------- EXPOSURE CONTROLS/ PERSONAL PROTECTION ---------------

8.1 REFER TO SECTION 7.

8.2 PERSONAL PROTECTIVE EQUIPMENT: Wear respirator, hand gloves, side covered safety
goggles provide eyewash fountains and
emergency shower near work area.
SECTION 9. --------------------- PHYSICAL AND CHEMICAL PROPERTIES -----------------------

9.1 MELTING POINT: 159 - 1620C

9.2 BOILING POINT: -NA-
9.3 SPECIFIC GRAVITY (WATER = 1) 250 / 250 : 0.4 gm/cc To 0.7 gm/cc
9.4 VAPOUR PRESSURE (MM Hg): -NA-
9.5 VAPOUR DENSITY (AIR = 1): -NA-
9.6 EVAPORATION RATE : Nil
9.7 SOLUBILITY IN WATER: Insoluble
9.8 APPEARANCE & ODOUR: Almost white powder. Almost odourless.
PHYSICAL STATE: Solid

SECTION 10. ------------------------- STABILITY AND REACTIVITY ----------------------------------

10.1 CHEMICAL STABILITY: Stable

10.2 CONDITION TO AVOID: Expose to heat
10.3 HAZARDOUS DECOMPOSITION -NA-
PRODUCTIONS:
10.4 MATERIAL TO AVOID: Oxidies
10.5 INCOMPABILITY: Oxidies
10.6 REACTIVITY: Oxidies
10.7 HAZARDOUS REACTION PRODUCTS: -NA-
SECTION 11. -----------------------------TOXICOLOGICAL INFORMATION -------------------------

11.1 May be harmful if inhaled.

11.2 May be harmful if swallowed.
11.3 To the best of our knowledge, the chemical, physical and toxicological properties have not been
thoroughly investigated.
11.4 Only selected registry of toxic effects of chemical substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
RTECS No: DB2944937
Acute toxicity: oral toxicity (LD50): 2000 mg/kg (rat)
Primary irritant effect:
On the skin: not known; may be an irritant
On the eye: not known; may be an irritant
Ingestion: may have harmful gastrointestinal effects; individuals with known hypersensitivity or
allergic reaction to other NSAID family members or sulfonamides should avoid exposure

SECTION 12. ------------------------- ECOLOGICAL INFORMATION ----------------------------------

Do not allow product to enter drinking water supplies, waste water or soil.

SECTION 13. -------------------------- DISPOSAL CONSIDERATIONS ----------------------------------

Dissolve or mix material with a suitable combustible solvent and incinerate in a chemical incinerator
equipped with an afterburner and scrubber.
Material should be disposed of in keeping with all local and national legislation. Packaging should be
disposed of in keeping with all local and national legislation. Handle contaminated containers as
product.

SECTION 14. --------------------------- TRANSPORT INFORMATION ----------------------------------

UN/Id No: Not regulated

DOT:
Proper shipping name: Not Regulated
SECTION 15. -------------------------- REGULATORY INFORMATION --------------------------------
15.1 NAME OF FIRM: M/s AARTI DRUGS LTD.
15.2 MAILING ADDRESS: W-61, MIDC, Tarapur, Thane
Maharashtra -401 506, INDIA.
15.3 TELEPHONE & FAX: (02525) 72826 & Fax- (02525) 72826
15.4 LOCAL BODIES INVOLVED: Collector of Thane.

SECTION 16. -------------------------- OTHER INFORMATION -------------------------------------------

The information contained in this material data sheet is believed to be reliable but no representation,
guarantee or Warranties, of any kind are made as to its accuracy, suitability for a particular application
or results to be obtained from them. It is whoever ensure that the information contained in the
material safety data sheet is revalent to the product manufactured / handled or sold as the case may be
by us.
M/s AARTI DRUGS LTD. makes no warranties expressed or implied in respect of the adequacy of
this document for any particular purpose.

NA - Not Available; ND - No Data; NL - Not Listed; NP – Not Pertinent; x - applicable.