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Original Article

MAGPI technique for distal penile hypospadias;


modifications to improve outcome at a
single center
Arvind K. Shukla, Aditya P. Singh, Pramila Sharma, Jyotsna Shukla1
Departments of Pediatric Surgery and 1Physiology, SMS Medical College, Jaipur, Rajasthan, India

ABSTRACT
Background: Hypospadias is the most common congenital anomaly of urogenital organs in boys. We reviewed our experience with
modification in the meatal advancement and glanuloplasty incorporated (MAGPI) technique of hypospadias repair. We point out some
modifications and outcomes of this technique in this study.
Patients and Methods: We identified all patients who underwent modified MAGPI repair of the distal hypospadias by a single
surgeon over a 10‑year period. We performed a retrospective chart review by outdoor assessment postoperatively. We assessed
parents’ satisfaction with functional and cosmetic outcomes. Decision to undergo this type of repair was intraoperative, depending
on position and mobility of the meatus, and the quality of periurethral tissue. We made some modifications in the original technique
of the MAGPI including no trimming of the edge of the glans in granuloplasty, incorporation of the collar in the granuloplasty; leading
to glans augmentation and taking stay suture over the ventral wall of the urethra with some perimeatal tissue.
Results: Our study was a retrospective analysis. We collected data retrospectively and outcomes were assessed by the outpatient
department visits in follow‑up. We identified 150 patients, with a median age of 6 years (3–8 years). Position of meatus was glanular
90 (60%) or coronal 60 (40%). Chordee was minimal in our study and was corrected by only penile degloving. Urethral stenting was
required in all patients for 3–4 days. There was no case of fistula, meatal regression, stenosis, mucosal prolapse, or second procedure.
Cosmetic outcome was deemed satisfactory in 98% (147/150).
Conclusion: In selected cases, our modifications in the MAGPI hypospadias repair provide excellent functional and cosmetic outcomes
with minimal complications.

Key words: Distal hypospadias, hypospadias repair, meatal advancement and glanuloplasty incorporated

Introduction anomaly of urogenital organs in boys, with an incidence


of approximately 1 in 250 newborns.[1] Recently, case
Hypospadias is a condition in which the location of selection has been advised to avoid possible complications
the urethral meatus is on the ventral aspect of the and limitations. While the meatal advancement and
penis. Hypospadias is the most common congenital glanuloplasty incorporated (MAGPI) repair continues to give
satisfactory outcomes, its critics have noted its association
Address for correspondence: Dr. Aditya P. Singh, with meatal regression and meatal stenosis. Our aim was
Department of Pediatric Surgery, SMS Medical College, Jaipur,
to review our experience with some modifications in the
Rajasthan, India.
E‑mail: dr.adisms@gmail.com
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DOI: How to cite this article: Shukla AK, Singh AP, Sharma P, Shukla J.
10.4103/ais.ais_37_16 MAGPI technique for distal penile hypospadias; modifications to improve
outcome at a single center. Arch Int Surg 2016;6:201-5.

© 2017 Archives of International Surgery | Published by Wolters Kluwer - Medknow 201


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Shukla, et al.: Modified MAGPI technique to improve outcome

original MAGPI repair to reduce complications and improve The outdoor assessment consisted of assessing parental
outcome. satisfaction and complications. Outdoor assessment was
done by cosmetic appearance (conical shape glans, meatus,
Patients and Methods scarring) and parent satisfaction.

We retrospectively reviewed all patients who underwent Surgical technique


MAGPI hypospadias repair in our department from 2005 Surgery was performed under general anesthesia and
to 2015 by one surgeon. This was followed by assessment caudal block with infiltration with 1:100000 xylocaine and
in the follow‑up clinic during interview with the parents or adrenalin solution. Circumferential subcoronal incision was
patients. The decision to undertake this type of repair was made [Figure 2]. Degloving of the penis was done up to the
intraoperative, depending on the position and mobility of mid penile region leaving behind a 2 mm size “Firlit collars.”
the meatus as well as the quality of periurethral tissue and A longitudinal incision was made in the stenotic meatus
quality of the urethra pxoximal to the meatus. We performed 2 mm proximally and calibrated with 10 Fr size silastic
MAGPI in the glanular, coronal (exclude subcoronal), NG tube. The meatal advancement was accomplished by a
stenotic meatus, excluding cases with deep glanular groove, Heineke–Mikulicz vertical incision and horizontal closure
wide urethral plate, and proximal urethra adherence to using 6‑0 vicryl of the transverses septum just distal to the
the skin. To test its mobility, the meatus should be pulled meatus. Then, the stay suture was placed over the ventral
distally using a Micro‑Adson forceps. Surgical technique wall of the urethra with some perimeatal tissue and pulling
was in accordance with the original MAGPI technique with it forward. Glanduloplasty was done without dissection and
some modifications [Figure 1], including no trimming of the trimming of the glans. Vertical mattress sutures PGA 6‑0
edge of the glans in granduloplasty and incorporation of the were taken incorporating the collar. Dorsal prepuce was cut
collar in the granduloplasty, leading to glans augmentation in the midline to cover the penile shaft. Size 6‑Fr NG tube
and taking stay suture over the ventral wall of the urethra was passed and left in situ. Simple penile dressing was
with some perimeatal tissue. The mean outpatient follow‑up
done. Catheter was removed after 3–4 days.
period was 1 year. All patients were reviewed 5 times. We
analyzed adverse outcomes such as meatal stenosis,
meatal regression, fistula, persistent chordee, mucosal Results
prolapse, poor cosmesis, and the need for reoperation.
The total number of patients who underwent this type
of repair during the study period was 150. The patients’
age at surgery ranged from 3 to 8 years, with a mean
age of 6 years. Ninety patients were aged 5–6 years. The
characteristics of the patients are shown in Table 1. Overall
outcome was deemed satisfactory in 98% (147/150) of the
cases. There were no urinary complaints in our study.
a b

c d
a b

c d
Figure 2: Preoperative (a), Intraoperative (b and c) and postoperative
e f view of our modified MAGPI technique (d) postoperative view of our
Figure 1: (a-f) Pictorial diagram of the steps of surgical technique modified MAGPI technique

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Shukla, et al.: Modified MAGPI technique to improve outcome

There was no persistent chordee and did not require any method in glandular type, whereas the tubularized incised
dorsal plication to correct chordee in our study. There plate (TIP) repair is preferred for other cases of distal
was no case of urethral mucosal prolapse. There was hypospadias.[3] The MAGPI procedure allows the surgeon to
no case of fistula, meatal regression, or meatal stenosis. avoid an urethroplasty, and provides a reliable, reproducible
None of the patients had a second procedure for a procedure for reconfiguring the glans and meatus without
complication [Table 2]. Good urinary stream and follow‑up the use of catheters and with a very low morbidity rate. The
images are shown in Figure 3. MAGPI technique was devised by Duckett in 1981.[4]

Distal hypospadias is the most common variety accounting


Discussion for 70% of all cases.[4,5] Though the MAGPI technique offered
More than 300 surgical techniques for hypospadias repair improved cosmetic and functional results without the need
have been described.[2] The MAGPI repair is the preferred for formal urethroplasty, complications and limitations of
the procedure have been reported. The reported incidence
of complications following MAGPI repair, which required
Table 1: Characteristics of 150 patients with hypospadias
reoperation, ranges from 1.2 to 10%.[6,7] There was no
Variable Value reoperation in the present study. Meatal regression
Total number 150
and stenosis remain commonly cited problems. Meatal
Age range 3‑8 years (6 years)
regression occurs when the glanduloplasty does not hold.
Operative findings
Glanular 90 Proponents of the procedure have attributed high rates of
Coronal 60 meatal regression and stenosis to poor patient selection
Chordee Minimal chordee with those selected having a meatus located too far
Chordee require correction Nil proximal and those with severe chordee.[6] We included only
Stenting All
glandular and coronal hypospadias with minimal chordee
and excluded more proximal hypospadias in our study.
Table 2: Outcome of treatment in patients that had modified MAGPI Chordee was corrected by degloving only up to the mid
surgery shaft. It did not require any dorsal plication in our study.
Variable Value
We had no complication in our study because we followed
Total number 150 case selection criteria to repair hypospadias. Modifications
Overall satisfied 98% (147/150) to the initial description have been described to reduce
Dissatisfied 2% (3/150) the incidence of meatal regression by bringing glandular
Complications tissue together in a more solid ventral closure.[6] We had
Mucosal prolapse Nil
a modification in our study. We incorporated the collar in
Persistent chordee Nil
Fistula Nil
the glanduloplasty, which helped us in augmentation of the
Meatal regression Nil glans. An additional layer approximating deep glans tissue
Meatal stenosis Nil was added that replaced the vertical mattress stitches in
Second procedure Nil the initial description. Epithelial layer closure superficially
was also incorporated to secure closure. We repaired glans
with the collar in simple or vertical mattress sutures in
our study. Meatal stenosis occurs when the meatus is too
narrow; therefore, using the Heineke–Mikulicz procedure
of cutting vertically to open the dorsal aspect of the meatus
and suturing transversely can minimize this complication.[7]
There was no meatal stenosis in our study. We performed
a b adequate ventral meatotomy and calibration with a 10‑Fr
NG tube. Considering the complications or limitations of
the procedure, many alternative techniques are available.
The majority are based on neourethra formation, which is
usually associated with higher morbidity rate and perhaps
less satisfactory cosmetic results.[8,9]

c d In our study, we performed modified MAGPI up to the


Figure 3: (a) Good urinary stream and (b-d) follow-up images age of 8 years because later in age the glandular tissue

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Shukla, et al.: Modified MAGPI technique to improve outcome

does not remain supple and causes complication related and the quality of the urethra pxoximal to the meatus.
to repair. Distal hypospadias has no functional problems We performed MAGPI in the glandular, coronal (exclude
and is rarely associated with fibrous chordee. There subcoronal), and stenotic meatus, excluding cases with
was minimal chordee in our study because we included deep glandular groove, wide urethral plate, and proximal
only glandular and coronal hypospadias. Patients’ main urethra adherent to the skin. In our study, there was no
concern is the deviation and splaying of urinary stream mucosal prolapse. Some authors recommended mucosal
in addition to unacceptable cosmetic appearance. Our prolapse as a complication but in our study we did not find
experience as well as that of other surgeons showed that, any such problem and with no urinary complaints. There
though most of the cases achieved good cosmetic results, was skin tag after glanduloplasty in our study, however,
the technique cannot be applied universally to all types it was not so problematic, and in follow‑up, it looks like a
of distal hypospadias.[10] Most authors reported excellent frenulum after remodeling.
results with glandular hypospadias, however, in cases
of coronal and subcoronal hypospadias, complications It is important not to stretch indications for MAGPI repair
were constantly reported.[11] We only included coronal such as selecting patients with a proximal meatus. Issa
hypospadias with shallow glandular groove and mobile and Gearhart reported 8 cases of meatal regression; 5
urethra in our study. had meatal regression which was attributed to a technical
failure, and 3 had severe regression suggesting poor patient
Variations of MAGPI procedure have been reported to selection.[11] On the other hand, Gibbons has suggested that
make this procedure amenable to borderline cases such cases with subcoronal meatus or possible chordee are
as coronal hypospadias, megameatus, and cases with suitable for MAGPI with some modification to the technique.
chordee. Somoza et al. described removing a triangular He described a creation of a vascularized meatal‑based
segment of glandular tissue distal to the meatus, and flap, which provides excellent flexibility.[14] One of the few
dissection of the dorsal and lateral urethral sides, disadvantages of the MAGPI repair is the unsatisfactory
accomplishing the urethral advancement without any look of the meatus, and some surgeons would argue that
tension. Strips of glandular epithelium are excised on a nice slit‑like meatus could hardly be fashioned by a
each side, and glans tissue is sutured above the ventral nonmodified MAGPI repair. In our experience, this has not
urethral wall.[12] Another modification was not to dissect been a commonly encountered issue. The key of success
and trim the glans for glanduloplasty with incorporation in our study is proper intraoperative selection criteria for
of the collar leading to tensionless repair, so we did not MAGPI.
have any fistula, meatal regression, and meatal stenosis
in our study. While Duckett et al.[6] reported complication This careful selection resulted in excellent outcomes
rate as fistula (0.45%), meatal regression (0.6%), no meatal from the modified MAGPI procedure with no meatal
stenosis, second surgery (1.2%), and residual chordee in stenosis or meatal regression. On the other hand, we
0.09%. Our results are more favorable than the original could be criticized for choosing a case of megameatus
MAGPI repair. The presences of distal chordee, glandular for MAGPI repair, as it was advised that this type of
tilt, fibrotic urethral meatus, or thin paraurethral skin hypospadias would best be repaired using the pyramid
are important limiting factors for MAGPI. Case selection or Mathieu procedure.[6] Nevertheless, other reports have
has been advised to avoid the possible complications of suggested that megameatus intact prepuce (MIP) variant
the meatal regression and stenosis.[13] We followed case of hypospadias is not an absolute contraindication for this
selection strictly in our study, and hence, we did not have type of repair, with published satisfactory success rates.[15]
any complication with better functional and cosmetic Corpus spongiosum advancement is a new technique
outcome in our study. The hypospadiac penis that is ideal for distal hypospadias repair. This procedure has
amenable to the MAGPI is characterized by a dorsal web several advantages over many other procedures currently
of tissue within the glans that deflects the urine from either employed for repair of distal hypospadias.[16]
a glandular or a slightly subcoronal meatus. The urethra
itself must have a normal ventral wall, without any thin or Conclusions
atretic urethral spongiosum, and it must be mobile such
that it can be advanced into the glans. Excellent surgical results are determined by meticulous
surgical technique and careful case selection. Our aim of
The decision to undertake this type of repair was study is to show the importance of the case selection and
intraoperative, depending on the position and mobility some modifications in the original MAGPI technique to
of the meatus and the quality of periurethral tissue, improve the results in term of complications, functionality,

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Shukla, et al.: Modified MAGPI technique to improve outcome

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be decided after case selection intraoperatively. 1111 patients. Ann Surg 1991;213:620‑5.
7. Ghali AM, el‑Malik EM, al‑Malki T, Ibrahim AH. One‑stage
hypospadias repair. Experience with 544 cases. Eur Urol
Financial support and sponsorship 1999;36:436‑42.
Nil. 8. Devine CJ Jr, Horton CE. Hypospadias repair. J Urol
1977;118:188.
Conflicts of interest 9. King LR. Cutaneous chordee and its implication in
hypospadias repair. Urol Clin North Am 1981;8:397.
There are no conflicts of interest. 10. Ozen HA, Whitaker RH. Scope and limitations of the MAGPI
hypospadias repair. Br J Urol 1987;59:81.
References 11. Issa MM, Gearhart JP. The failed MAGPI: Management and
prevention. Br J Urol 1989;64:169‑71.
1. Baskin LS, Himes K, Colborn T. Hypospadias and endocrine 12. Somoza I, Liras J, Abuin AS, Mendez R, Tellado MG, Rios J,
disruption: Is there a connection? Environ Health Perspect et al. New Modern Magpi. Cir Pediatr 2004;17:76‑9.
2001;109:1175‑83. 13. Duckett JW, Snyder HM. Meatal advancement and
2. Germiyanoglu C, Nuhoglu B, Ayyildiz A, Akgul KT. glanuloplasty hypospadias repair after 1000 cases:
Investigation of factors affecting result of distal hypospadias Avoidance of meatal stenosis and regression. J Urol
repair: Comparison of two techniques. Urology 2006;68:182‑5. 1992;147:665.
3. Springer A, Krois W, Horcher E. Trends in hypospadias surgery: 14. Gibbons MD. Nuances of distal hypospadias. Urol Clin North
Results of a worldwide survey. Eur Urol 2011;60:1184‑9. Am 1985;12:169‑74.
4. Duckett JW. MAGPI (meatoplasty and glanuloplasty): 15. Bar‑Yosef Y, Binyamini J, Mullerad M, Matzkin H,
A procedure for subcoronal hypospadias. Urol Clin North Ben‑Chaim J. Megameatus intact prepuce hypospadias
Am 1981;8:513‑9. variant: Application of tubularized incised plate
5. Sweet RA, Schrott HG, Kurland R, Culp OS. Study of the urethroplasty. Urology 2005;66:861‑4.
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