ruler established Lu 1

Inheritance

3.4 alleles are separated so that

Gratia

inheritance each gamete carrier 1 allele per gene

Mendel s Law principles of 2 Law of independent Assortment allele segregation for

crossed breaded
types of pear grew a gere ocurre independently to any other gene except linked

them to determine its characteristics gener

Ex height color 3 principle of Dominance dominant alleles mark receive one

crossed many offspring with each other come genes are co dominant or incomplete dominan a

to have the pure of each characteristics

Mary crosses establish reliability

Experiment results

when crossed 2 dif pear together no blend

Ex tall t Short tall

Self fertilised offspring traits 2 diff traits

expressed in 3 1 ratio

ex tall t tall 3 tall 1 short

conclusion of experiments

1 organismo have discrete factors gero that Types of zygoyity V 4

determine its features

2 Organism possess 2 version allele from
G a meter haploide a allele per gene
Feiffer
Mom Dad

each factor Possible allele combination in

any gene

3 Each gamete contains 1 version of each FEMALE offspring

guauen eye color gene

factor

4 Parents contribute equally in inheritance A dominant

of offspring pent egg a recessive

5 Each factor hora dominant version

over another and will be

expressed

Aa
Aa


Modes of Inheritance 0.5 Inheritance of ABO blood groups A 1

Genotype gere composition for specific trait ABO blood groups are controlled by gene with many alfiler

heterozygous or
homozygous

Phenotype observable characteristics of A and B co dominant

specific trait

O recessive

Traits follow dominant recessive

pattern one allele is expressed Dunnett Grid 5 1

over
the other monohybrid cross determiner

allele combination of

Offspring for 1 gere

Dominant is expressed over reavive monohybrid correr Dunne

grid

are
only probabilities

co dominance allele pairs are both when comparing predicted data

equally expressed in phenotype of outcome larger datasets more

heterozygous individual likely to have positive correlation like Mendel

Alleles have a
joint effect

6 136 136
L 100
4
a
Chance of black rat

B 6
ti chance of black rat Irv of
Y

Y f n brown rat n


Genetic Disearer autosomal direarer v 6

caved when a mutation of a s normal

gere

cell function diseased phenotype

carriers heterozygous individuals with 1 faulty allele

A 3

1 Recessive Cystic Fibrosis

Mutation of CFTR gere chromosome 7

Produce mucho that clogs airways and

digestive system respiratory and pancreatic failure

Heterozygous carriers No symptoms

2Dominant Huntington's Direare

Mutation in Huntington gene HIT chromosome 4

Nucleotide sequence AG repeats 40 timer

hunting tin protein mis folds neurodegeneration

symptoms dementia uncontrolled movements

appear age 40 Genetic Disease generalities v a

No carriers dominant allele Diseased recessive alleles are more Common

there con be hidden by dominant allele

3 Co dominant Di reared dominant condition tend to appear late

Sickle cell anemia Mhealthy
mutation in red blood cell hemoglobin k faulty in life

faulty carrier might already heredited

RBC symptoms faulty allele to offspring

susceptible to malaria not anemic

16 16 o

HEHE malaria resistance mild anemia

Hb Hb

suceptible tu malaria severe anemia E

Sex linked Inheritance IV 7

X chromosome is larger than Y chromosome

most sex linked conditions are from X mostly

females XX

V 8

females XX Carriers only female

Homozygous men have one X

Heterozygous Maler ALWAYS inherit X

from mom Y from dad

Mater XY Female CANNOT inherit

Hemizygow recerrive condition from

dad only DOMINANT allele from

dad

Ex Rat eye color XI red XI white

a
I X XY 6 1 X XY

red mom white dad Whiteman red dad

red eyes soi

red
Xr Ifk dominant white
WAI

X
X y
xk
Y

100
M
EEEEE

redeyer SOY red

sr white


Ex Albinism A a

I A AA Aa

a Aa aa

I a lo vi albino

no Pedigree has 44 albino

conclusions Therefore pedigree ave

Albino is not y linked more accurate for limited

parents are heterozygous
Aa
carrierrdat

Punnetts for direarer

CYSTIC FIBROSIS HUNTINGTON

Pedigree Charts

Genetic family history over several generations

male rey
affected

female ay

RED GREEN COLOR BLIND

Hemophilia y

sickle cell anemia

Slide 53

slide 71

Bioknowledgy 3.4

child