1.

Mean corpuscular hemoglobin (MCH)

● It is the average hemoglobin content of a single red cell
● MCH = _Hb in g/dl
RBCs count 1 gram = 103 milligram
1 milli = 103 micro
Example 1 micro = 103 nano
If Hb concentration = 15 g/dl 1 nano = 103 picogram
RBCs count = 5 million/mm3 1 pico = 103 femto
Find out the MCH 1 gram = 1012 Pico

1 ml = 1000 mm3

MCH = 15 g/100ml = 15 X 1012 Pico /100ml (15x1012)

5X106 /mm3 (5X106) X (103) X (102)/100ml = (5x1011)

MCH = 15 x 10 = 30 Picogram.
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● Normal range of MCH: 27 – 31 Picograms

● Abnormal high result (Hyperchromic anemia)

- Folate deficiency and pernicious anemia

● Abnormal low result (Hypochromic anemia)

- Iron deficiency anemia and Thalassemia
 Examples of different forms of anemia
 Iron deficiency anemia is described as microcytic and hypochromic
 Vitamin B12 deficiency is macrocytic and normochromic