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  • Mean Corpuscular Volume (MCV)

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    amir elhadi
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    1. Mean corpuscular volume (MCV) is the average volume of a single red blood cell, calculated by dividing the packed cell volume by the red blood cell count. 2. The normal range for MCV is 80-100 femtoliters. 3. Abnormally high MCV, or macrocytic anemia, can indicate folate deficiency, pernicious anemia, or vitamin B12 deficiency due to lack of intrinsic factor. Abnormally low MCV, or microcytic anemia, can be caused by iron deficiency anemia or thalassemia.

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    Mean corpuscular volume (MCV)

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    1. Mean corpuscular volume (MCV) is the average volume of a single red blood cell, calculated by dividing the packed cell volume by the red blood cell count. 2. The normal range for MCV is 80-100 femtoliters. 3. Abnormally high MCV, or macrocytic anemia, can indicate folate deficiency, pernicious anemia, or vitamin B12 deficiency due to lack of intrinsic factor. Abnormally low MCV, or microcytic anemia, can be caused by iron deficiency anemia or thalassemia.

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    17 views1 page

    Mean Corpuscular Volume (MCV)

    Uploaded by

    amir elhadi
    1. Mean corpuscular volume (MCV) is the average volume of a single red blood cell, calculated by dividing the packed cell volume by the red blood cell count. 2. The normal range for MCV is 80-100 femtoliters. 3. Abnormally high MCV, or macrocytic anemia, can indicate folate deficiency, pernicious anemia, or vitamin B12 deficiency due to lack of intrinsic factor. Abnormally low MCV, or microcytic anemia, can be caused by iron deficiency anemia or thalassemia.

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    1.

    Mean corpuscular volume (MCV)

    ● It is the average or the mean volume of a single red cell


    1 milli = 103 micro
    ● MCV = _ PCV_ __
    RBCs count 1 micro = 103 nano
    1 nano = 103 pico
    Example 1 pico = 103 femtolitre
    If PCV = 45 % = (45ml / 100 ml)
    1 milli = 1012 femto
    RBCs count = 5 million/mm3 Find out the MCV:
    1 ml = 1000 mm3
    MCV = 45 ml/100ml = 45 X 1012 (Femto /100ml) (45x1012)
    5X106 /mm3 (5X106) X (103) X (102)/100ml = (5X1011)

    MCV = 45 x 10 = 90 femtolitre .
    5
    ● Normal range of MCV: 80 – 100 Femtolitres

    ● Abnormal high result ( Macrocytic anemia )


    - Folate deficiency and pernicious anemia
    (Pernicious anemia is one of megaloblastic anemias caused by impaired absorption
    of vitamin B12 because of a lack of intrinsic factor (IF) in gastric secretions)

    ● Abnormal low result ( Microcytic anemia )


    - Iron deficiency anemia and Thalassemia
    ( Thalassemia is an inherited blood disorder characterized by less hemoglobin and
    fewer red blood cells )

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