Professional Documents
Culture Documents
Maternal Notes
Maternal Notes
I. HUMAN SEXUALITY
A. Concepts
1. A person‘s sexuality encompasses the complex behaviors, attitudes emotions & preferences that are related
to sexual self & eroticism.
2. Sex – basic & dynamic aspect of life
3. During reproductive years, the nurse performs as resource person on human sexuality.
*Gender Identity -sense of femininity or masculinity *Gender Identity : 3 y/o or 2-4 y/o
Stage 4 – occurs between ages 13 & 14, hair assumes the normal appearance of an adult but is
not so thick & does no appear to the inner aspect of the upper thigh.
Stage 5- Sexual maturity- normal adult- appears to the inner aspect of upper thigh .
b. Labia Majora – ―large lips‖- longitudinal fold , extends symphysis pubis to perineum
c. Labia Minora or ― Nymphae‖—soft & thin longitudinal fold located bet labia majora
2 Sensitive Structures
1. Clitoris- ―Pea-shaped‖- Anterior portion. Erectile tissue w/ lots sensitive nerve endings.
Sight of sexual arousal (Greek-key)
1
4. Vaginal Orifice – external opening of vagina
5. Bartholene‘s Glands- Paravaginal gland or vulvo gland -2 small mucus secreting substance
– secrets alkaline subs. *Neutralizes the vagina
*Alkaline – neutralizes acidity of vagina
*Ph of vagina - acidic
*Doderleins Bacillus – responsible for the acidity of vagina
*Carumculae Mystiformes- healing of torn hymen
2. Internal
b. Uterus- organ of menstruation--a hollow, thick walled muscular organ. It varies in size,
weight & shape
Size - 1 x 2 x 3 meters
Shape: Non-pregnant ―Pear shaped‖
Pregnant – ―Ovoid‖
Muscular Compositions: 3 main muscle layers which make expansion possible in every direction.
1. Endometrium- inside uterus, lines the nonpregnant uterus. *Muscle layer for menstruation.
Sloughs during menstruation.
*Decidua- thick layer w/c lines the pregnant uterus.
Endometriosis-abnormal growth of endometrial lining outside uterus―Ectopic endometrium‖
Common site: Ovary.
S/sx: Dysmennorhea & low back pain.
Dx: Biopsy & Laparoscopy
Meds: 1. Danazol (Danocrene)---action: stop menstruation & inhibits ovulation
2. Luprolide (Lupron) –action: inhibit FSH/LH production
2. Myometrium – largest part of the uterus, muscle layer for delivery process
Its smooth muscles are considered to be the living ligature of the body.
Power of labor, responsible for contraction of the uterus
3. Perimetrium – Protects entire uterus
4 Significant Segments
1. External
Penis – the male organ of copulation & urination. It contains of a body of a shaft
consisting of 3 cylindrical layers and erectile tissues. At its tip is the
most sensitive area comparable to clitoris in the female – glands penis.
3 Cylindrical Layers
*2 Corpora Cavernosa
*1 Corpus Spongiosum
Scrotum – a pouch hanging below the pendulous penis, with a medial septum
dividing into two sacs, each of which contains a testes.
- cooling mechanism of testes
- < 2 degrees C than body temp.
- Leydig cell – release testosterone
Testes---- for continuous spermatogenesis
2. Internal
The Process of Spermatogenesis – maturation of sperm
Urethra
*Androphous-------male menopause
Male Female
Sperm Ovum
GnRH Penile Glans Clitoral Glans
Penile shaft Clitorial shaft
Anterior Pituitary Gland Testes Ovaries
Prostate Skene‘s Glands
Cowper‘s Glands Bartholene‘s Glands
Scrotum Labia Majora
FSH LH
3
Secondary Sex Characteristics
Female Male
1. in height in weight
2. in pelvis diameter Growth of testes
3. Breast enlargement Growth of face, axillary & pubic hair
4. Pubic hair growth Voice changes
5. Onset of menstruation Penile growth
6. Growth of axillary hair in height
7. Vaginal secretions Spermatogenesis
8. Menstruation:
Menstrual Cycle------------------- beginning of menstruation to beginning of next menstruation
Average Menstrual Cycle –------ 28 days
Average Menstrual Period-------- 3 – 5 days
Normal Blood loss---------------- 50 cc or ¼ cup, accompanied by ―Fibrinolysin‖—prevents clot formation
Related Terminologies:
Menarche--------– 1st mens
Dysmenorrhea – painful menstruation -----give Mefenamic: act as anti-prostaglandin
Metrorrhagia-----bleeding between menstruation
Menorhagia ------excessive during menstruation
Amenorrhea-------absence of menstruation
Menopause --------cessation of mens. *Average menopausal age : 51 years old
-dependent on the # of kids you have
Needs of Menopausal Women: Menopause
Estrogen
Constipation
I. On the initial 3rd phase of menstruation , the estrogen level is ,this level stimulates the hypothalamus to
release GnRH or FSHRF
Functions of FSH:
III. 13th day of menstruation, estrogen level is peak while the progesterone level is , these stimulates the
hypothalamus to release GnRF / LHRF
S & Sx:
Mittelschsmerz – the slight abdominal pain on L or RQ of abdomen, marks ovulation day.
Change in BBT, mood swing
5
Functions of LH:
IX. 24th day if no fertilization, corpus luteum degenerate becoming whitish---------Corpus Albicans
X. 28th day – if no sperm in ovum – endometrium begins to slough off to begin the next menstruation
Physiology: Hypothalamus
FSH LH
1. Excitement Phase – erotic stimuli cause increase sexual tension, lasts minutes to hours.
Sx: for both---- moderate increase in HR, RR,BP, sex flush, nipple erection, increase muscle tension
2. Plateau Phase – increasing & sustained tension nearing orgasm. Lasts 30 seconds – 3 minutes.
Sx: for both--- increase voluntary & involuntary muscle, accelerated V/S
3. Orgasm – immeasurable peak of sexual experience & involuntary spasm throughout body. Involuntary release of sexual
tension with physiologic or psychologic release. May last 2 – 10 sec- most affected are is pelvic area.
Sx: involuntary spasm throughout body, peak v/s
Male: 2-3 contraction
Female: 5-12 contraction
*Refractory Period – the only period present in males, w/n he cannot be restimulated for about 10-15 minutes
A. Fertilization
*Pre-embryonic Stage
a. Zygote ------fertilization up to 14th day.
------Lifespan of zygote – from fertilization to 2 months
b. Morula ----- mulberry-like ball with 16 – 50 cells/ 4 days free floating & multiplication
c. Blastocyst – enlarging cells that forms a cavity & later becomes the embryo.
*Trophoblast ---- covering of blastocys that later becomes placenta & trophoblast
*Cornix- where sperm is deposited after entering the vagina
*Sperm- small head, long tail, pearly white
*Phonones-vibration of head of sperm to determine location of ovum
6
*Sperm should penetrate corona radiata and zona pellocida.
*Corona Radiata – outer layer of ovum
*Zona Pellucida – inner layer of ovum
*Capacitation- ability of sperm to release proteolytic enzyme to penetrate corona radiata & zona pellocida.
d. Implantation/ Nidation - occurs after fertilization 7 – 10 days.
3 processes of Implantation
1. Apposition
2. Adhesion
3. Invasion
*If with fertilization – corpus luteum continues to function & become source of estrogen & progesterone
while placenta is not developed.
Blastocysts
*Embroyonic Stage
* Basalis: (base) part of endometrium located under fetus where placenta is developed,
this is located where implantation occurs
* Capsularies – encapsulate the fetus/ located on the backside
* Vera – remaining portion of endometrium.
f. Chorionic Villi- finger life projections that develops 10 – 11th day of pregnancy
*Chorionic Villi Sampling (CVS) ----- removal of tissue sample from the fetal portion of the developing placenta for
genetic screening.
>Done early in pregnancy around 9-12 wks.
>Common complications: Fetal limb defect. Ex. missing digits/toes.
g. Cytotrophoblast –outer layer or ―Langhans layer‖ – protects fetus against syphilis up to 24 wks/6 months
then degenerates at 16 wks.
7
b. Amniotic Fluid – or ―Bag of Water‖
a. Amniocentesis
N.I : Empty bladder before performing the procedure.
Purpose : Obtain a sample of amniotic fluid by inserting a needle through the abdomen
into the amniotic sac; fluid is tested for:
c. Fern Test- determine if bag of water has ruptured or not. Done for laboring mother
8
Functions of Placenta:
1. Respiratory System- exchange of O2 & CO2 via simple diffusion
-use it as the breathing system not the lungs
- beginning of lung function after 1st cry of baby.
2. GIT –as a transport center like glucose transport thru facilitated diffusion (rapid)
If mom hypoglycemic then fetus hypoglycemic too
3. Excretory System- waste products carried by arteries. Liver of mom detoxifies waste.
*Entire pregnancy days : 266 – 280 days or 37 – 42 weeks *280/28 days = 10 lunar months
*280/30 days = 9.7 calendar month
First trimester: Period of Organogenesis/ Development of Organs
*Most Critical Period
* Ectoderm -Brain, CNS, skin, 5 senses, mucus membrane of hair, nails, anus & mouth
9
Second Trimester: Period of Continuous Growth & Development
*Focus ----length of fetus
4th Month :
Lanugo begins to appear
FHT audible by fetoscope (18 – 20 wks.)
Buds of permanent teeth appear
Meconium is present
5th Month :
Quickening : 1st fetal movement used for EDC (Primi: 18- 20 wks.) (Multi: 16- 18 wks)
Lanugo covers body
Actively swallows amniotic fluid
FHT audible by stet w/ or w/o instrument
19-25 cm fetus
Actively swallow amniotic fluid
6th Month :
Eyelids open
Skin red & wrinkled
Vernix caseosa covers the skin
Exhibits startle reflex
Sucking
7th Month:
Development of surfactant – lecithin
Male : testes begin to descend into scrotal sac
Female : clitoris is prominent & labia majora are small & do not cover labia minora
8th Month:
Lanugo begin to disappear
Sub Q fats deposits, steady weight gain occurs
Nails extend to fingers
Active Moro reflex is present
Nails longer to fingers
9th Month:
Lanugo & vernix caseosa begins to thin
Amniotic fluid decreases
Birth position is assumed
Sole of foot has few creases
10th Month:
Bone ossification of fetal skull
Vernix caseosa is evident in body folds
TO CONSIDER:
Terratogens- any drug, virus or irradiation, the exposure to such may cause damage to the fetus
A. Drugs:
Streptomycin – anti TB & or Quinine (anti malaria) – damage to 8th cranial nerve : Ototoxicity & deafness
Tetracycline – staining of tooth enamel, inhibits growth of long bone
Vitamin K – Hemolysis, hyperbilirubenimia or jaundice
Iodides – enlargement of thyroid or goiter
Thalidomides – Amelia (absence of extremities) or pocomelia (Absence of distal parts of extremeties)
Steroids – cleft lip or palate or abortion
Lithium – anti-manic may cause congenital malformation
B. Alcohol – LBW (vasoconstriction –monther/ FAS or fetal alcohol syndrome ---characterized by microcephaly
C. Smoking – LBW
10
D. Caffeine – LBW
E. Cocaine – LBW w/c causes vasoconstriction leads to abruptio placenta
CHARACTERISTICS: group of infections caused by organisms that can cross the placenta or ascend through birth
canal and adversely affect fetal growth and development. These infections are often characterized by vague,
influenza like findings, rashes and lesions, enlarged lymph nodes, and jaundice (hepatic involvement). In some
chases the infection may go unnoticed in the pregnant woman yet have devastating effects on the fetus.
1. Systemic Changes
A. Cardiovascular System
Normal increase blood volume of mother----- 1,500 cc (+500 for multiple pregnancy)
Plasma volume increase only
Increase cardio workload-------easy fatigability
Slight hypertrophy of ventricles
Epistaxis d/t hyperemia of nasal membrane
Palpitation d/t stimulation of CNS
Normal Values
Hct 32 – 42%
Hgb 10.5 – 14g/dL
Criteria
1st and 3rd trimester : HCT >33% & Hgb >11g/dL
Pathologic anemia if lower
2nd trimester – Hct >32% & Hgb >10.5 g/dl
Pathologic anemia if lower
3. Pathogenic Anemia
-Iron deficiency anemia is the most common hematological disorder.
It affects 20% of pregnant women.
Assessment reveals:
Pallor, constipation
Slowed capillary refill * Normal Capillary Refill: 2-3 seconds)
Concave fingernails (late sign of progressive anemia) d/t chronic physio hypoxia
Nursing Care:
Nutritional instruction
Sources of Iron: kangkong---most common source
Liver ---richest source d/t ferridin content
Green leafy vegetable-alugbati,saluyot, malunggay, horseradish, ampalaya
Parenteral Iron ( Imferon) – for severe anemia
give IM---Z tract- if improperly administered------Hematoma
Oral Iron supplements (ferrous sulfate 0.3 g. 3 times a day)
-Anti-sebum: best given before meals or 2 hrs after, black stool, constipation
Monitor for hemorrhage
Alert:
Iron from red meats is better absorbed iron from other sources.
Iron is better absorbed taken w/ Vit. C such as orange juice
Higher iron intake is recommended since circulating blood volume is increased & heme is required
from production of RBCs
11
4. Edema – lower extremities in pregnant women normal--- d/t venous return---constricted d/t large belly
N.I. -----Elevate legs above hip level
*Responsible for venous return----muscle contraction
B. Respiratory System
C. Gastrointestinal
4. Heartburn or Pyrosis
-Reflux of stomach content to esophagus
N.I.----- small frequent feeding, avoid 3 full meals
Diet: avoid fatty & spicy food, sips of milk
Proper body mechanics----avoid downward positioning
*Ptyalism-- --increase salivation---– mgt mouthwash
12
5. Hemorrhoids
-Cause by pressure of gravid uterus
N.I.----Hot sitz bath for comfort, avoid hot & spicy foods
C. Urinary System
-Frequency of urination: 1st & 3rd trimester only
-Lateral expansion of lungs or side lying pos – mgt for nocturia
D. Musculoskeletal
2. Waddling Gait – awkward walking dt relaxin – causes softening of joints & bones
N.I.----Prone to accidental falls – wear low heeled shoes
3. Leg Cramps
-Causes: prolonged standing, over fatigue,chills, oversex
- #1 cause during pregnancy: Ca & phosphorous imbalance
- During labor: Compression of lumbo sacral nerve plexus by the gravid uterus
-Immediate relief---dorsiflexed feet
Mgt: Increase Ca & Inc phosphorus)----milk ---1pint/day or 3-4 servings/day.
Cheese, yogurt, head of fish, Dilis, sardines with bones, brocolli,
seafood-tahong (mussels), lobster, crab.
Vit D for increased Ca absorption
2. Local Changes
A. Vagina:
U – Hegar's Sign -------- -change in consistency of isthmus (lower uterine segment)
C – Goodel's Sign -------change in consistency of cervix
V – Chadwick‘s Sign ---bluish violet discoloration of vagina &cervix
a. Vaginitis
-CA: Trichomonas vaginalis---a Flagellated protozoan – likes alkaline env‘t.
-D/t alkaline environment of vagina of pregnant mom
-Pregnant: acidic to alkaline change to protect bacterial growth (vaginitis)
S & Sx:
-Greenish, cream-colored frothy discharge
-Irritatingly itchy with foul smelling odor with vaginal edema
Mgt:
1. Anti-protozoan ----FLAGYL (Metronidazole).
-Teratogenic drug especially at 1st trimester (do not give too early)
-Treat also the partner to prevent reinfection
-No alcohol-----antaabuse effect
2. VAGINAL DOUCHE – I quart H2O : 1 tbsp white vinegar
b. Moniliasis or Candidiasis
-CA: Candida Albecans ( a fungal infection)
S & Sx:
-White cheese-like patches that adheres walls of vagina.
- Baby with oral thrust if vaginal delivery
Mgt:
1. Antifungal------Nystatin, Mycostatin, Gentian violet, Cotrimaxole
13
c. Gonorrhea
-Thick purulent discharge
d. Vaginal Warts
- Condylomata Acuminata
-CA: Papilloma virus
Mgt: Cauterization
B. Abdominal Changes
C. Skin Changes
A. Presumptive: S/S felt & observed by the mother but does not confirm (+) dx of pregnancy------ Subjective
B. Probable : Signs observed by the members of health team------Objective
C. Positive Signs: Undeniable signs confirmed by the use of instrument.
*Ballotment - bouncing of fetus when lower uterine is tapped sharply (also present in uterine myoma)
*Braxton Hicks– painless irregular contractions
14
VI. Psychological Adaptation to Pregnancy
1st Trimester:
No tanginal S & Sx
Feeling of Surprise, Ambivalence & Denial – sign of maladaptation to pregnancy
Developmental Task: Accept the biological facts of pregnancy
HT Focus: Bodily changes of pregnancy & nutrition
2nd Trimester:
Tangible S&Sx
Mother identifies fetus as a separate entity d/t presence of quickening
Fantasy
Developmental Task: Accept growing fetus as baby to be nurtured
HT: Growth & Development of fetus.
3rd Trimester:
Mother has personal identification w/ the appearance of the baby
Development Task: Prepare for birth & Parenting of child
HT: Responsible parenthood ---best time to prepare ‗baby‘s Layette‖ ,Lamaze class, shopping.
Allay fear of mother-----let mom listen to FHT
VII. Pre-Natal Visit:
Basic Considerations:
3. Diagnosis of Pregnancy
1.) Urine Exam---to test for HCG –present on 40 – 100th day of pregnancy
*Peak of HCG : 60th – 70th day
*Do Urine test: 6 weeks after LMP- best to get urine exam.
2.) Elisa Test – test for early pregnancy to detect beta subunit of HCG as early as 7 – 10days
4. Baseline Data:
a. Focus: V/S especially BP
b. Roll-Over Test – to determine pre-eclampsia
-Side-lying position 10-15 minutes then supine & get BP, if >30/15mmHg (+)
c. Monitor patterns of weight gain (Increase wt – 1st sign preeclampsia)
Weight Monitoring
1st Trimester: Normal Weight Gain 1.5 – 3 lbs (.5 – 1lb/month)
2nd Trimester: Normal Weight Gain 10 – 12 lbs (4 lbs/month) or (1 lb/wk)
3rd Trimester: Normal Weight Gain 10 – 12 lbs (same w/ 2nd)
*Minimum Wt Gain: 20 – 25 lbs
*Optimal Wt Gain: 25 – 35 lbs
15
5. Obstetrical Data:
a. Nullipara – no pregnancy
b. Gravida - # of pregnancy
c. Para - # of viable pregnancy
*Viability – the ability of the fetus to live outside the uterus at the earliest possible gestational age,
still counted if the stillbirth is more than 20 wks old.
*Age of Viability: 20 weeks
*Abortion : <20 weeks
*Term : 37 – 42 wks.
*Preterm : >20 & <37 wks
*GTPAL: 5 digits----Gravida, Para, Term, Abortion, Living
Sample Cases:
1 – abortion GTPAL *Twins: considered as 1 pregnancy
1 – 2nd mo 2 0 01 0
G–2
P–0
1 – 40th AOG GT P A L
1 – 36th AOG 612 2 4
2 – miscarriage
1 – twins 35 AOG
1 – 4th month G6 P3
Important Estimates:
Formula:
If LMP: January-March + 9 months April – December: - 3 months
+ 7 days + 7 days
+ 1 year
Ex. LMP Jan 25, 04 then +9 +7 = 10 / 32 / 04 = - 1, add 1 month to month = 11/31/04 EDD
2. McDonald’s Rule : Use to determine age of gestation IN WEEKS, if LMP not available
16
6. Tetanus Immunizations
- Best way to prevent tetanus neonatum
- Given 5 times
- Mother w/ complete 3 doses DPT in childhood considered as TT1 & 2. Begin TT3
7. Physical Examination:
Result:
Class I - Normal
Class IIA – Acytology but no evidence of malignancy
B – Suggestive of inflammation
Class III – Cytology suggestive of malignancy
Class IV – Cytology strongly suggestive of malignancy
Class V – Cytology conclusive of malignancy
2. Leopold’s Maneuver
Purpose: Done to determine the attitude, fetal presentation, lie, presenting part,
degree of descent, an estimate of the size & # of fetuses, position,
fetal back( best site for FHT) & FHT
N.I.
- Use palm! Warm palm by rubbing briskly w/ each other
- Empty bladder
- Position mother: Dorsal Recumbent : supine w/ knee flex to
17
relax abdominal muscles)
Procedure:
1st maneuver: Place patient in supine position with knees slightly flexed; put towel under
head & right hip; w/ both hands palpate upper abdomen & fundus.
Assess size, shape, movement & firmness of the part
to determine presentation:
2nd Maneuver: W/ both hands moving down, identify the back of the fetus (to hear FHT)
where the ball of the stethoscope is placed to determine FHT.
*Take Pulse before 2nd maneuver to differentiate between
Fundic soufflé (FHR) & Uterine soufflé (MHR)
3rd Maneuver: Using the right hand, grasp the symphis pubis part using thumb & fingers.
To determine degree of engagement.
4th Maneuver: Examiner changes the position by facing the patient‘s feet. With 2 hands,
assess the descent of the presenting part by locating the cephalic
prominence or brow.
To determine attitude – relationship of fetus to 1 another.
When the brow is on the same side as the back, the head is extended.
When the brow is on same side as the small parts, head will be
flexed & vertex presenting.
A. Ultrasound
b. Nonstress Test: To determine the response of the fetal heart rate to activity
Indication – pregnancies at risk for placental insufficiency
Position: Semi-fowler‘s
a.) PIH, DM
b.) Warning signs noted during DFMC
c.) Maternal history of smoking, inadequate nutrition
d.) Postmaturity
18
Procedure:
Done w/n 30 minutes wherein the mother is in semi-fowler‘s position (w/ fetal
monitor); external monitor is applied to document fetal activity; mother activates the
―mark button‖ on the electronic monitor when she feels fetal movement.
Interpretation of Results
1. Reactive Result
a. Baseline FHR between 120 & 160 beats per minute
b. At least two accelerations of the FHR of at least 15 beats per minute, lasting at least
15 seconds in a 10 to 20 minute period as a result of FM
c. Good variability – normal irregularity of cardiac rhythm representing a balanced
interaction between the parasympathetic (decreases FHR) & sympathetic (increase
FHR) nervous system; noted as an uneven line on the rhythm strip.
d. Result indicates a healthy fetus with an intact nervous system
2. NonReactive Result
a. Stated criteria for a reactive result are not met
b. Could be indicative of a compromised fetus.
Requires further evaluation with another NST, biophysical profile, (BPP)
or contraction stress test (CST)
9. Health Teachings
19
Recommended Nutrient Requirement That Increases During Pregnancy
20
- Formation of RBC & more then 2 times the daily prepregnant veal
prevention of anemia requirement. 300mcg/day supplement for - dark green leafy
- DNA synthesis & cell women with low folate levels or dietary vegetables, broccoli,
formation; may play a role in deficiency legumes.
the prevention of neutral tube *4 servings of grains/day - Whole grains, peanuts
defects (spina bifida), abortion,
abruption placenta
Additional Requirements Increased requirements of
Minerals pregnancy can easily be met with
- Iodine 175 mcg/day a balanced diet that meets the
- Magnesium 320 mg/day requirement for calories &
- Selenium 65 mcg/day includes food sources high in the
other nutrients needed during
pregnancy.
Vitamins Vit. stored in body
E 10 mg/day -Fat soluble Vits.---ADEK
Thiamine 1.5 mg/day -Not taken daily, can lead to
Riborlavin 1.6 mg/day toxicity. Hard to excrete.
Pyridoxine ( B6) 2.2 mg/day
B12 2.2 mg day
Niacin 17 mg/day
Principles Of Exercise
1. Done in moderation
2. Must be individualized
c. Tailor Sitting –same with squatting--- 1 leg in front of other leg ( Indian seat)
f. Pelvic rocking/pelvic tilt- exercise – relieves low back pain & maintain good posture
* Arch back – standing or kneeling. Four extremities on floor
g. Abdominal Exercise – strengthens muscles of abdomen– done as if blowing candle
c. Childbirth Preparation:
Overall goal: To prepare parents physically & psychologically while promoting wellness
behavior that can be used by parents & family thus, helping them achieved a satisfying &
enjoying childbirth experience.
21
1. Bradley Method : By Dr. Robert Bradley
-Advocated active participation of husband as a coach at delivery process.
Based on imitation of nature.
Features:
1.) Darkened room
2.) Quiet environment
3.) Relaxation technique
4.) Closed eye & appearance of sleep
b. Psychosexual
a. Uterine Stretch Theory: Any hallow organ stretched, will always contract & expel its content)- contraction action
22
2. The 4 P’s of labor
1. Passenger (baby)
2. AnteroPosterior Diameter
Suboccipitobregmatic: 9.5 cm (complete flexion, smallest AP)
Occipitofrontal: 12 cm partial flexion
Occipitomental: 13.5 cm hyper extension
Submentobragmatic: Face presentation
Moldings: Overlapping of the sutures of the skull to permit passage of the head to
the pelvis
Problems in Passageway :
1. Mother < 4‘9‖ tall
2. < 18 years old
3. Underwent pelvic dislocation, or accident (cephalopelvic disproportion)
a. Pelvis
4 Main Pelvic Types
1. Gynecoid: Round, wide, deeper most suitable for pregnancy (Normal female pelvis)
2. Android: Heart shape ―male pelvis‖- anterior part pointed, posterior part shallow
3. Anthropoid: Oval, ape like pelvis, oval shape, AP diameter wider, transverse narrow
supine A
Transverse
P
*Gynecoid & Anthropoid- can deliver vaginally
23
3 Parts of 2 Innominate Bones
1. Diagonal Conjugate – measure between sacral promontory & inferior margin of the
symphysis pubis.
Measurement: 11.5 cm - 12.5 cm
Basis in getting true conjugate.
(Formula : DC - 11.5 cm = True conjugate)
2. True Conjugate/Conjugate Vera – measure between the anterior surface of the sacral
promontory & superior margin of the symphysis pubis.
Measurement: 11.0 cm
3. Obstetrical Conjugate: smallest AP diameter of pelvis at 10 cm or more. Where the head will pass
3. Power – the forces acting to expel the fetus & placenta *Myometrium – powers of labor
a. Involuntary Contractions
b. Voluntary bearing down efforts
c. Characteristics: wave like
d. Timing: frequency, duration, intensity
4. Psyche/Person – psychological stress when the mother is fighting the labor experience
a. Cultural Interpretation
b. Preparation
c. Past Experience
d. Support System
3. Pre-Eminent Signs of Labor
S&Sx:
- Shooting pain radiating to the legs
- Urinary frequency
1. Lightening: Settling of presenting part into pelvic brim. (Primi: 2 weeks prior to EDD)
(Multi- hours before labor)
* Engagement- setting of presenting part into pelvic inlet
Nursing Care;
Administer Analgesics (Morphine)
Attempt manual rotation for ROP or LOP – most common malposition
Bear down with contractions
Adequate hydration – prepare for CS
Sedation as ordered
Cesarean delivery may be required, especially if fetal distress is noted
Cord Prolapse – a complication when the umbilical cord falls/ is washed thru the cervix into the vagina.
*Cord Compression---if 5 minutes leads to irreversible brain damage---cerebral palsy
*An emergency-----position to a knee-chest or trendelenberg position
Danger Sx:
PROM
Presenting part has not yet engaged
Fetal distress----count pulsations of cord
Protruding cord from vagina
Nursing Care:
1. Cover cord with sterile gauze with saline to prevent drying of cord so cord will remain
slippery & prevent cord compression
2. Slip cord away from presenting part
3. Count pulsation of cord for FHT
4. Prep mom for CS
5. Emotional support
4. Duration of Labor
Primipara : 14 hrs & not more than 20 hrs
Multipara : 8 hrs & not > 14 hrs
* Entocia -----normal labor
*Dystocia-----difficult labor
A. First Stage: Onset of true contractions to full dilation & effacement of cervix.
Latent Phase:
Assessment: Dilations: 0 – 3 cm
Frequency: every 5 – 10 min
Mother: Excited, apprehensive, can communicate
Intensity: Mild
Nursing Care:
a. Encourage walking - shorten 1st stage of labor
b. Encourage to void q 2 – 3 hrs : Full bladder inhibit contractions
c. Breathing : Chest breathing
Active Phase:
Assessment: Dilations: 4 -8 cm
Frequency q 3-5 min lasting for 30 – 60 seconds
25
Intensity: Moderate
Mother: Fears losing control of self
Nursing Care:
M – edications – have meds ready
A – ssessment include: V/S, cervical dilation & effacement, fetal monitor, etc.
D – dry lips – oral care (ointment)
dry linens
B – abdominal breathing
Transitional Phase:
Assessment: Dilations: 8 – 10 cm
Frequency q 2-3 min contractions
Durations 45 – 90 seconds
Intensity: Strong
Mother: Mood suddenly changes accompanied by hyperesthesia
*Hyperesthesia – increase sensitivity to touch, pain all over
Health Teaching :
Teach: Let father do Sacral pressure on lower back to inhibit transmission
of pain to the brain (gate theory)
Keep informed of progress
Controlled chest breathing
Nursing Care:
T – ires
I – nform of progress
R – estless support her breathing technique
E – ncourage & praise
D – iscomfort
B. Pelvic Exams
Effacement – softening & thinning of cervix. Use % in unit of measurement
Dilation – widening of cervix. Unit used is cm
*Both accomplished by uterine contractions
a. Station – relationship of the presenting unit to the ischial spine. Landmark used: Ischial Spine
-3 Station: Needs Therapeutic rest
- 2 Station: Presenting part 2 cm above ischial spine if (-) floating
- 1 station : Presenting part 1cm above ischial spine if (-) floating
0 Station: At level at ischial spine : Engagement
+ 1 station : Below 1 cm ischial spine
+3 to +5 : Crowning occurs at 2nd stage of labor
b. Presentation/lie – the relationship of the long axis (spine) of the fetus to the long axis of the mother
-spine of mom and spine of fetus
Two Types:
26
c. Position – relationship of the fetal presenting part to specific quadrant of the mother‘s pelvis.
Variety:
Occipito:LOA left occipito ant (most common & favorable position)– side of maternal pelvis
LOP – left occipito posterior
LOP – most common malposition, most painful
ROP – squatting position for mother
ROT, ROA
Shoulder/Acromniodorso
LADA, LADT, LADP, RADA
Chin / Mento
LMA, LMT, LMP, RMP, RMA, RMT, RMP
Parts of Contractions:
Increment or Crescendo – beginning of contractions until it increases
Acme or Apex – height of contraction
Decrement or Decrescendo – from height of contractions until it decreases
Duration – beginning of 1 contraction to end of same contraction
Interval – end of 1 contraction to beginning of next contraction
Frequency – beginning of 1 contraction to beginning of next contraction
Intensity - strength of contraction
*Best time to get BP & FHT -----just after a contraction or midway of contractions
Health Teachings:
1.) Ok to shower: bath as necessary
2.) Mom has headache – check BP, if same BP, let mom rest. If BP increase , notify MD -preeclampsia
3.) NPO – GIT stops function during labor if with food---vomiting & aspiration---chemical neumonitis
4.)Enema administer during labor
a.)To cleanse bowel
b.)Prevent infection
c.) Sims position/side lying, 12 – 18 inch – height ofenema tubing
5.) Check FHT after administration of enema *Normal FHT: 120-160 bpm
6.) Encourage to void
7.) Perineal prep-----7 method, S position
8.) Left side-lying position to prevent supine hypotension-----Supine Vena Caval Syndrome
9.) Give analgesic ( Demerol) , Meperidine HCl---narcotic, anti-spasmodic
Given in active phase, not latent phase
No barbiturates----no antidote
S/E: Respiratory Depression
Antidote: Narcan-Naloxone---to baby only
Signs of Fetal Distress:
1.) <120 & >160
2.) Mecomium stain amnion fluid
3.) Fetal Thrushing: hyperactive fetus due to lack O2
27
B. Second Stage: Complete dilation & effacement to birth.
“Fetal Stage”
Mechanisms of labor
1. Engagement
2. Descent
3. Flexion
4. Internal Rotation
5. Extension
6. External rotation
7. Expulsion
Nursing Care:
- If 7 to 8 cm , multipara – bring to delivery room
- If 10 cm primipara – bring to delivery room
- Lithotomy position – put legs same time up
- A Bulging of perineum – sure sign that the baby is about to be delivered
- Teach Breathing: Pant & blow breathing, push w/ open glottis
EPISIOTOMY:
-Assist in doing episiotomy- to prevent laceration, widen vaginal canal, shorten 2nd stage of labor.
-Use local anesthesia or natural anesthesia or pudendal
- Ironing the perineum – to prevent laceration
2 Types:
Median Mediolateral
-Less Bleeding -More Bleeding
- Less Pain - More pain
- Easy Repair - Hard to repair
- Fast Healing - Slow to heal
- May lead to urethrouanal fistula - No major disadvantage
3 Parts Of Pelvis:
*Linea Terminales : Diagonal imaginary line from the sacrum to the symphysis pubis that
divides the false & true pelvis.
28
Nursing Care:
To prevent puerperal sepsis - < 48 hours only – vaginal pack
Bolus of Ptocin can lead to hypotension.
1. Shultz: ―Shiny‖ – begins to separate from center to edges presenting the fetal side.
2. Dunkan : ―Dirty‖ – separate from edges to center presenting maternal side – beefy red or dirty
29
Complications of Labor:
Types:
a. Hypertonic or Primary Uterine Inertia
- Intense excessive contractions resulting to ineffective pushing
- MD administer sedative ( Valium, diazepam – muscle relaxant)
b. Hypotonic or Secondary Uterine Inertia
- Slow irregular contraction resulting to ineffective pushing
- Give oxytocin
2. Prolonged Labor : labor of more than 20 hrs. for primi, >14 hrs. for multipara d/t ineffective pushing
Causes:
1.) Previous Classical CS----once classical, always classical
2.) Large baby
3.) Improper use of oxytocin (IV drip)
S/Sx:
1. Sudden pain
2. Profuse bleeding
3. Hypovolemic shock -----prepare for TAHBSO
* Physiologic Retraction Ring - Boundary between upper & lower uterine segment
* BANDL‘S Pathologic Ring - suprapubic depression, a sign of impending uterine rupture
S/Sx:
1. Dyspnea
2. Chest pain
3. Frothy sputum
Prepare: Suctioning
30
End Stage: DIC (Disseminated Intravascular Coagopathy)
- bleeding to all portions of the body – eyes, nose, etc.
7. Trial Labor
- Measurement of head & pelvis falls on borderline. Mom given 6 hrs of labor
- Multipara: 8 – 14 hrs. & Primipara 14 – 20 hrs.
8. Preterm Labor
- Labor after 20 & before 37 wks.)
Triad S/Sx:
1. Premature contractions q 10 minutes
2. Effacement of 60 – 80%
3. Dilatation of 2-3 cm
Home Mgt:
1. CBR
2. Avoid sex
3. Empty bladder
4. Drink 3-4 glasses of water – full bladder inhibits contractions
5. Consult MD if symptoms persist
Hospital Mgt:
1. If cervix is closed 2 – 3 cm, dilation saved by administer
Tocolytic agents- halts preterm contractions.
Ex. YUTOPAR- ( Ritodrine Hcl)
S/E: Sustained tachycardia---antidote---Propanolol (Magnesium Sulfate)
Monitor: FHT > 180 bpm
Maternal BP - <90/60
Crackles – notify MD – pulmonary edema
– administer oral yutopar 30 minutes before d/c IV
a. Physiologic Changes
1. Systemic Changes
Cardiovascular System
- the first few minutes after delivery is the most critical period in mothers because the increased in
plasma volume return to its normal state & thus adding to the workload of the heart. This is critical
especially to gravidocardiac mothers.
- After 24 hrs.-----Normal increase WBC up to 30,000 cumm (Normal WBC: 10,000- 15,000 mm)
Monitor:
1. Increase plasma volume to 1,500 cc
2. Sudden decrease in BP
3. Elevated WBC up to 30,000 um
31
4. Increase temperature w/n the 1st 24 hr. post-partum is normal
After 24 hrs.----a sign of infection
5. Foul-smelling lochia ----a sign of infection
6. V/S every 15 minutes, every 30 minutes 2 hrs. after
7. Hyperfibrinogenia
8. Orthostatic hypotension
Genital Tract
a. Cervix - Check cervical opening
b. Vaginal & Pelvic Floor
c. Uterus
- Return to normal 6 – 8 wks.
-Fundus goes down 1 finger breath/day until 10th day – no longer palpable already
behind symphisis pubis
d. Lochia
Components of WBC: blood, WBC, deciduas, bacteria, microorganism.
Both NSD & CS with lochia.
Urinary Tract:
Bladder : Frequency in urination after delivery d/t urinary retention with overflow
Dysuria Post-Partum---cause by damage to the trigone of the bladder
Mgt:
1. Urine collection
2. Alternate warm & cold compress
3. Stimulate bladder
Colon:
Constipation d/t NPO, fear of bearing down of tearing laceration
Perineal Area:
Lateral Sims position for painful perineum
For episiotomy site: Cold compress if (+) pain post-delivery followed by warm compress
After 24 hrs. recommend hot sitz bath, not compress
Sex- when perineum has healed
1. Psychological Responses:
32
b. Taking Hold Phase:
― Dependent to Independent Phase‖
- 4 to 7 days
- Mother: Active, can make decisions
- Focus HT: Care of newborn & Family Planning Method
c. Letting Go Phase:
- ―Interdependent Phase‖
- 7 days & above
- Mother redefines new roles as parents may extend until child grows.
1. Uterine Atony
S/Sx:
- Baggy or relaxed uterus
- Profuse bleeding
Complications: Hypovolemic shock
Mgt:
1.) Massage uterus only if w/ uterine atony until contracted
2.) Cold compress
3.) Modified trendelenberg
4.) IV fast drip/ oxytocin IV drip
5.)Breastfeeding for sucking--- PPG will release oxytocin so uterus will contract.
2. Lacerations
S/Sx:
- Well-contracted uterus
- Profuse bleeding
- Assess perineum for laceration
- Degree of laceration
- Mgt: Episiorapy
Types: 1st degree laceration – affects vaginal skin & mucus membrane.
2nd degree – 1st degree + muscles of vagina
3rd degree – 2nd degree + external sphincter of rectum
4th degree – 3rd degree + mucus membrane of rectum
33
4. Hematoma
- Bluish or purple discoloration of SQ tissue of vagina or perineum.
- Candidate if there is too much manipulation
- Delivery of very large baby
- Pudendal anesthesia
Mgt:
- Cold compress q 10-20 minutes with rest period of 30 minutes for 24 hrs
- Shave
- Incision on site, scraping & suturing
Mgt:
- D&C or manual extraction of fragments & massaging of uterus.
- D&C except in 3 cases:
2. Infection
Sources of infection:
a. Endogenous – from within body
b. Exogenous – from outside
Causes:
a. Anaerobic streptococci – most common - from members HT
b. Unhealthy sexual practices
General Mgt:
a. Supportive care: CBR, hydration, TSB, cold compress, analgesic, Vit. C
b. Culture & sensitivity – for antibiotic—shld be taken on time
prolonged use of antibiotic lead to superinfection Ex. fungal infection
Types of Infection:
a. Perineal Infection
-general signs + 2-3 stitches of dislodge w/ purulent discharcge
Mgt:
Removal of sutures & drainage, saline
b. Endometriosis/endomitritis
- general signs + Inflammation of endometrial lining + addominal tenderness
Mgt:
Fowler‘s Position to facilitate drainage & localize infection
Oxytocin & antibiotic
c. Thrombophelibitis
34
IV. Motivate The Use Of Family Planning
Principles:
1.) Determine one‘s own beliefs 1st
2.) Never advice a permanent method of planning
3.) Method of choice is an individual choice.
4.) Informed Consent
d. Symptothermal
- Combination of BBT & cervical.
- Most effective natural method
2. Social Method
3. Physiologic Method:
a. Pills – combined oral contraceptives prevent ovulation by inhibiting the anterior pituitary gland
production of FSH & LH w/c are essential for the maturation & rupture of a follicle.
- 99.9% effective.
- Waiting time to become pregnant- 3 months.
- Consult OB-6mos.
Contraindications:
-Chain Smoking
- HPN
- DM
- Heart Disease
- Extreme obesity
- Thrombophlebitis
- Problems in clotting factors
35
Alerts on Oral Contraceptive:
- In case a mother who is taking an oral contraceptive for a long time plans to have a baby, she would
wait for at least 3 months before attempting to conceive to provide time for the estrogen &
progesterone levels to return to normal.
- If a new oral contraceptive is prescribed the mother should continue taking the previously prescribed
contraceptive & begin taking the new one on the first day of the next menses.
A – abdominal pain
C – chest pain
H - headache
E – eye problems
S – severe leg cramps
*If mother taking pills & there‘s increase in BP ----stop pills STAT!
- If forgotten for one day, immediately take the forgotten tablet plus the tablet scheduled that day. If
forgotten for two consecutive days, or more days, use another method for the rest of the cycle and the
start again.
b. DMPA :
- Depomedroxy Progesterone Acetate (Depo-proveda)
- Inhibits ovulation: has progesterone inhibits LH
- IM q 3 months
- Never massage injected site, may lessen the duration of effectivity
c. Norplant
- Composed of 6 match sticks – like capsules implanted subdermally containing progesterone.
- Good for 5 yrs – disadvantage if keloid skin
- As soon as removed – can become pregnant
Alerts:
-Right time to insert is after delivery or during menstruation
- Primary indication for use of IUD : Parity or # of children, if 1 kid only don‘t use IUD
-Most common complication: Excessive Menstrual Flow & Expulsion of the device
- 99.7% effective.
- Does not give protection against Syphilis
Others:
P-eriod late (pregnancy suspected)
Abnormal spotting or bleeding
A -bdominal pain or pain with intercourse
I - nfection (abnormal vaginal discharge)
N -ot feeling well, fever, chills
S - trings lost, shorter or longer
b. Condom :
- Made of Latex inserted to erected penis or lubricated vagina
- Prevents the sperm to enter the uterus
Alerts:
Disadvantage:
It lessen sexual satisfaction
It gives higher protection in the prevention of STDs
Highest protection against STDs----Female condom
c. Diaphragm
- Rubberized dome-shaped material inserted to cervix preventing sperm to get to the uterus.
Alerts:
-Reusable
- Keep in place 6-8 hrs. after intercourse
- Contraindication: UTI
HT:
1.) Proper hygiene
2.) Check for holes before use
3.) Must stay in place 6 – 8 hrs after sex
4.) Must be refitted especially if w/ weight change of 15 lbs
d. Cervical Cap
-More durable than diaphragm
- No need to reapply spermicide
- Could stay for more than 24 hrs.
C/I: Abnormal Pap Smear
5. Surgical Method
b. Vasectomy
- Cut at the vas deferense.
- >30 ejaculations before safe sex
- O – zero sperm count for at least 2 (-) results
1. Hemorrhagic Disorders
General Management:
1.) CBR
2.) Avoid sex
3.) Assess for bleeding (per pad 30 – 40cc) (wt – 1gm =1cc)
4.) Prepare mother for ultrasound to determine integrity of sac
5.) Signs of Hypovolemic shock
6.) Assess for bleeding: approximation
7.) Save discharges for histopathology : To determine if product of conception has been expelled
or not
37
A. First Trimester Bleeding:
b. Induced Abortion
Therapeutic abortion to save life of mother.
Double effect choose between lesser evil.
2. Ectopic Pregnancy
- Occurs when gestation is located outside the uterine cavity.
- Common site: Tubal or Ampular
- Dangerous site - interstitial
Unruptured Tubal rupture
1. Missed period 1. Sudden , sharp, severe pain. Unilateral radiating to shoulder.
2. Abdominal pain w/n 3 -5 wks of missed period 2. Shoulder pain (indicative of intraperitoneal bleeding that
(maybe generalized or one sided) extends to diaphragm & phrenic nerve)
3. Scant, dark brown, vaginal bleeding Pain occurs at site of ectopic preg.
4. Vague discomfort 3. (+) Cullen‘s Sign : bluish tinged umbilicus
Nursing Care: – signifies intra peritoneal bleeding
-V/S 4. Syncope (fainting)
- Administer IV fluids, Montir I & O Mgt: Surgery depending on site
- Monitor for vaginal bleeding Ovary: oophrectomy
- Prepare for culdocentesis: To determine Uterus : hysterectomy
hemoperitoneum
- Nonsurgical: Methotraxate
38
B. 2nd Trimester Bleeding
Assessment:
Health Teachings:
a. Return for pelvic exams as scheduled for one year to monitor HCG &
assess for enlarged uterus & rising titer indicative of choriocarcinoma
b. Avoid pregnancy for at least one year
2. Incompetent Cervix
- premature/early dilatation of cervix (18 wks.)
Factors:
a. Hormonal Imbalance
b. Abnormal Cervix
1. Placenta Previa – it occurs when the placenta is improperly implanted in the lower uterine segment,
sometimes covering the cervical os.
Abnormal lower implantation of placenta.
- Candidate for CS
3 Types:
a. Marginal
b. Partial
c. Complete
Assessment:
- Frank , bright red, painless bleeding ------Most Outstanding Sign
- Engagement (usually has not occurred)
- Fetal distress
- Presentation ( usually abnormal)
Dx:
- Diagnosed by ultrasound
39
Nursing Care:
- Bedrest-------initiate NPO-----candidate for CS
- Prepare to induce if cervix is ripe
- Administer IV
- Avoid IE, sex or enema – may lead to sudden fetal blood loss
- Double set up------informed consent---surgeon responsible & explain
------delivery room may be converted to OR
Surgeon – in charge of sign consent, RN as witness
MD explain to patient
2. Abruptio Placenta
Outstanding Sx: Dark red, painful vaginal bleeding, board like or rigid uterus.
Assessment:
Concealed bleeding (retroplacental)---inside—palpate a board-like abdomen
Couvelaire uterus (caused by bleeding into the myometrium)
(-) contraction of uterus d/t hemorrhage (uterine apoplexy)
Severe abdominal pain
Dropping coagulation factor (a potential for DIC)
Complications:
Sudden fetal blood loss
Placenta Previa & Vasa previa
Nursing Care:
Infuse IV, prepare to administer blood
Type & crossmatch
Monitor FHR
Insert Foley
Measure blood loss; count pads
Report S/S of DIC
Monitor v/s for shock
Strict I&O
*Dangerous Sign-------DIC----prepare for hysterectomy
3. Placenta Succenturiata: 1 or 2 more lobes connected to the placenta by a blood vessel may lead
to retained placental fragments if vessel is cut.
5. Placenta Marginata : Fold side of chorion reaches just to the edge of placenta
8. Vilamentous Insertion of cord : Cord divides into small vessels before it enters the placenta
9. Vasa Previa : Velamentous insertion of cord has implanted in cervical OS
D. Hypertensive Disorders
40
2. Transitional Hypertension
HPN between 20 – 24 wks & after that no more
Causes:
a. Idiopathic (unknown but multi-factorial)
b. Common in primis d/t 1st exposure to chorionic villi
c. Common in multiple pregnancy d/t increase exposure to chorionic villi
d. Mother w/ low socio-economic status d/t low intake of CHON
e. Teenager moms d/t/ low compliance
3 Types Of Pre-Eclampsia:
a. BP 160/110
b. Protenuria +3 to +4
Signs Present:
3.) Eclampsia
- With seizure!
- Increase BUN d/t glomerular damage & decrease CO2 combining power
- Provide safety.
Nursing Care:
a.BP decrease
b. Urine output decrease (<30 cc/hr)
c. Respiration < 12
d. Patella reflex absent – 1st sign Mg SO4 toxicity.
Antidote – Ca gluconate
41
PATHOPHYSIOLGY OF HYPERTENSION
O2 supply --------HPN
O2 O2 O2 O2
leads to
o
Pulmonary Edema f
Leads to
More CHF I
m
Cerebral Edema p
e
n
Cerebral Compression d
i
n
Cerebral Irritability g
Convulsion
CONVULSION
42
E. Diabetes Mellitus
- Absence or lack of insufficient insulin (Insulin produced in the Islet of Langerhans of pancreas)
Function of insulin : Facilitates transport of glucose to cell
Newborn Effect : DM
1.) Hyperinsulinism (1st)
2.) Hypoglycemia (<40mg/dl)
Sx of Hpoglycemia:
High pitch shrill cry
Tremors
Jitteriness
Sx:
Calcemia tetany
Trousseau Sign
Tx: Give calcium gluconate if decrease calcium
43
F. Heart Disease
Classifications:
*Mother with RHD at childhood
Recommendation:
1.) Early hospitalization by 7-8 months
1. Cesarean Delivery
Indications:
a. Multiple gestation
b. Diabetes
c. Active herpes II
d. Severe toxemia
e. Placenta previa
f. Abruptio placenta
g. Prolapse of the cord
h. CPD -------------------Primary indication for CS
i. Breech presentation
j. Transverse lie
2. INFERTILITY
- Inability to achieve pregnancy within a year of attempt
- Manageable
a. Sterility : Irreversible
b. Impotency: Inability to have an erection
2 Types Of Infertility
1.) Primary – no pregnancy at all
2.) Secondary – not able to become pregnant following 1st pregnancy
Infertility Test:
1.) Anovulation :
- No ovulation
- Most common problem d/t increase prolactin – hyperprolactinemia
45
STD leading to PID
Dx:
Hysterosalphingography:
-Used to determine tubal patency with use of radiopaque material
46
BASIC GENETICS & OBSTETRICS
I. PRINCIPLES
1. Alleles
- Refers to the different variations of a trait. Ex. Different eye color or hair color
b. Recessive gene for a trait is only expressed if the other gene in the pair is the same-recessive
3. GENOTYPE
- Refers to an individual‘s entire genetic make-up created when an ovum & sperm unite at fertilization
4. PHENOTYPE
- Refers to an individuals physical appearance that results from the manner in w/c his genotype is expressed
5. KARYOTYPE
- Photograph of an individual‘s chromosome used to diagnosed chromosomal aberrations
Criteria:
If 1 parent is affected & the other is normal = 50% chance in each pregnancy that baby is affected
= 50% chance in each pregnancy that baby is normal
MENDELIAN LAW
Ex.
Father Huntington’s Chorea
Retinoblastoma
Mother 25 25 Polydactyly
Achondroplasia (dwarfism)
25 25
Normal Gene: N (capital letter)
Defected Gene: d (small letter)
Criteria:
If 2nd gene is normal, abnormality is not expressed but the person is a carrier of the defected gene
w/ can be transmitted to offspring.
2 carriers of the recessive genes must each contribute for the abnormality to be expressed in the
baby.
Ex.
For each pregnancy: Cyctic Fibrosis
Sickle Cell Anemia
= 25 % chance that the baby is affected Galactosemia
= 25 % chance the baby is not affected Celiac Disease
= 50 % baby is a carrier Phenylketonuria (PKU)
Tay-sachs Disease
47
c. X – LINKED RECESSIVE INHERITANCE
Daughter
Son
Males severely affected when they receive the recessive gene from their mother since there is no
corresponding gene on their Y chromosome. Can only transmit to their female offspring
Females only express the disorder if they receive a recessive gene from mother & affected father
- Problems R/T absence or defect in enzyme responsible for metabolism of protein, fat or carbohydrate
leading to an accumulation of harmful substance (phenylalanine) or absence of a substance (thyroxine).
Criteria:
Follows an autosomal recessive pattern of inheritance
Physical & mental development severely affected as child grows older
Multifactorial inheritance:
Ex.
Cleft lip palate
Neural tube defects
Pyloric Stenosis
Congenital Heart Defects
- Defected gene carried on the X chromosome but is dominant & expressed in both male & female
offspring who inherit the defected gene
Criteria:
Males severely affected Ex.
Ricketts
48