PHARMACEUTICAL ENGINEERING

(Unit-wise Important question)

UNIT-I

5 Mark
1. Venturimeter.
2. Principle and working of sieve shaker.
3. Fluid energy mill.
4. Derive Bernoulli's theorem.
5. Factors affecting side reduction
6. Ball mill
10 Mark
1. Explain the mechanism of size reduction. Add a note on its pharmaceutical
application.
2. Explain the principle, construction, working, advantages and disadvantages of ball
mill.
3. Explain the Reynolds experiment and Bernoulli’s theorem of fluid flow.

UNIT-II

5 Mark
1. Application of distillation.
2. Forced circulation evaporator.
3. Heat interchangers.
4. Explain Fourier's law of heat transfer by conduction.
5. Fourier's law of heat conduction through a metal wall
6. Principle and methodology of flash distillation.
7. Mechanism of conduction
8. Various methods of heat transfer. Discuss convective heat transfer and tubular
heat exchanger.

10 Mark
1. Describe in detail about flash distillation with neat diagram.
2. Explain the factors affecting evaporation. Write about multiple effect
evaporators.
3. Describe the construction, working, principle, efficiency, merits and demerits
of fractional distillation.
 UNIT-III
5 Mark
1. Double cone blender.
2. Principle, construction and working of a freeze dryer.
3. Solid mixing.
4. Mechanism of liquid mixing.
5. Mechanism of solid mixing.
6. Sigma blade mixer
7. Spray dryer

10 Mark
1. Discuss in detail with a neat sketch construction, working and applications of freeze
dryer.
2. Explain the principle, construction and working of planetary mixer with merits and
demerits.
3. Give Theory of drying and explain in detail Spray dryer

UNIT-IV

5 Mark
1. Perforated basket centrifuge.
2. Mechanism of filtration.
3. Theories of centrifugation.
4. Explain the theories of filtration.
5. Principle and applications of centrifugation.
6. Filter leaf

10 Mark
1. Describe in detail about the principle, assembly and working of plate and frame filter
press with advantages and disadvantages
2. Define filtration. Write in detail about Plate and Frame filter press.

UNIT-V

5 Mark
1.Properties of glass.
2. Stainless steel as a material of pharmaceutical plant construction
3. Any three methods for prevention of corrosion.
4. Describe various types of iron as material of construction.

10 Mark
1.Describe various types of corrosion and suggest the possible methods to overcome.
 2 Marks

1. Define the term communication.

2. List out the specifications and standard for sieves.
3. Differentiate between mixing and agitation.
4. Define the term molecular distillation.
5. Mention few applications of evaporation in pharmacy.
6. Distinguish between critical moisture content and equilibrium moisture content.
7. Write the various factors affecting drying.
8. Write the significance of Reynold's number.
9. Sate Fourier's law of heat transfer.
10. Define the term filter aids and give examples.
11. Define & Types of corrosion.
12. Types of conveyors
13. Define conduction, convection and radiation
14. Applications of drying
15. Dalton's law
16. Applications of evaporation
17. Objective of centrifugation
18. Differentiate between Orifice meter and Venturi meter.
19. What are heat exchangers?
20. Stefan Boltzmann' s law.
21. Define EMC.
22. Advantages of bag filters.
23. Classify evaporators.
24. Laws governing size reduction.
25. Define conduction convection and radiation.
26. Draw rate of drying curve.
27. Centrifugation
28. Heat interchangers
29. Propellers
30. Define Elutriation
31. Application of distillation