Uji Normalitas

Notes

Output Created 08-SEP-2023 10:51:20

Comments
C:\Users\CATURWARGA
COMPUTER\OneDrive\
Data
Documents\analisis dara dr
nabila res THT.sav
Active Dataset DataSet1
Input
Filter <none>
Weight <none>
Split File <none>
N of Rows in Working Data
40
File
User-defined missing values
Definition of Missing for dependent variables are
treated as missing.
Missing Value Handling Statistics are based on cases
with no missing values for
Cases Used
any dependent variable or
factor used.
EXAMINE VARIABLES=y3
y4 y5 y6
/PLOT BOXPLOT
STEMLEAF NPPLOT
/COMPARE GROUPS
Syntax
/STATISTICS
DESCRIPTIVES
/CINTERVAL 95
/MISSING LISTWISE
/NOTOTAL.
Processor Time 00:00:00,66
Resources
Elapsed Time 00:00:01,29
 Case Processing Summary

Cases

Valid Missing Total

N Percent N Percent N Percent

IL-8 pre
20 50.0% 20 50.0% 40 100.0%
NAC+antibiotik topikal
IL-8 post
20 50.0% 20 50.0% 40 100.0%
NAC+antibiotik topikal
IL-8 pre antibiotik
20 50.0% 20 50.0% 40 100.0%
topikal
IL-8 post antibiotik
20 50.0% 20 50.0% 40 100.0%
topikal

Descriptives

Statistic Std. Error

Mean 155.3625 13.20982

95% Confidence Interval for Lower Bound 127.7140

Mean Upper Bound 183.0110

5% Trimmed Mean 153.8900

Median 126.1950

Variance 3489.984
IL-8 pre
Std. Deviation 59.07609
NAC+antibiotik topikal
Minimum 87.67

Maximum 249.56

Range 161.89

Interquartile Range 116.34

Skewness .614 .512

Kurtosis -1.307 .992

IL-8 post Mean 76.0275 7.93716
NAC+antibiotik topikal 95% Confidence Interval for Lower Bound 59.4148
Mean Upper Bound 92.6402
5% Trimmed Mean 74.8167
Median 67.4650
Variance 1259.970
Std. Deviation 35.49605
Minimum 27.21
 Maximum 146.64
Range 119.43
Interquartile Range 48.16
Skewness .887 .512
Kurtosis -.149 .992
Mean 137.5745 14.90327
95% Confidence Interval for Lower Bound 106.3816
Mean Upper Bound 168.7674
IL-8 pre antibiotik
5% Trimmed Mean 129.6483
topikal
Median 120.0350
Variance 4442.147
Std. Deviation 66.64944

Descriptives

Statistic Std. Error

IL-8 pre antibiotik Minimum 75.32

topikal Maximum 342.50

Range 267.18

Interquartile Range 68.02

Skewness 1.853 .512

Kurtosis 3.817 .992

Mean 131.0510 16.31069
95% Confidence Interval for Lower Bound 96.9123
Mean Upper Bound 165.1897
5% Trimmed Mean 121.4278
Median 101.5500
Variance 5320.774
IL-8 post antibiotik
Std. Deviation 72.94363
topikal
Minimum 65.20
Maximum 370.12
Range 304.92
Interquartile Range 60.57
Skewness 2.256 .512
Kurtosis 5.635 .992

Tests of Normality
 Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

IL-8 pre
.225 20 .009 .845 20 .004
NAC+antibiotik topikal
IL-8 post
.240 20 .004 .888 20 .025
NAC+antibiotik topikal
IL-8 pre antibiotik
.175 20 .109 .806 20 .001
topikal
IL-8 post antibiotik
.236 20 .005 .742 20 .000
topikal

a. Lilliefors Significance Correction

IL-8 pre NAC+antibiotik topikal

IL-8 pre NAC+antibiotik topikal Stem-and-Leaf Plot

Frequency Stem & Leaf

3,00 0 . 899
9,00 1 . 001122223
3,00 1 . 689
5,00 2 . 33444

Stem width: 100,00

Each leaf: 1 case(s)
IL-8 post NAC+antibiotik topikal

IL-8 post NAC+antibiotik topikal Stem-and-Leaf Plot

Frequency Stem & Leaf

1,00 2 . 7
1,00 3 . 2
2,00 4 . 45
3,00 5 . 255
4,00 6 . 2577
4,00 7 . 0229
,00 8 .
,00 9 .
 1,00 10 . 8
1,00 11 . 7
,00 12 .
1,00 13 . 2
2,00 14 . 56

Stem width: 10,00

Each leaf: 1 case(s)
IL-8 pre antibiotik topikal

IL-8 pre antibiotik topikal Stem-and-Leaf Plot

Frequency Stem & Leaf

8,00 0 . 77888999
6,00 1 . 012244
3,00 1 . 558
1,00 2 . 0
1,00 2 . 5
1,00 Extremes (>=343)

Stem width: 100,00

Each leaf: 1 case(s)
IL-8 post antibiotik topikal

IL-8 post antibiotik topikal Stem-and-Leaf Plot

Frequency Stem & Leaf

3,00 0 . 677
6,00 0 . 889999
4,00 1 . 0011
1,00 1 . 3
2,00 1 . 45
1,00 1 . 6
1,00 1 . 9
2,00 Extremes (>=257)
Stem width: 100,00
Each leaf: 1 case(s)
NPAR TESTS
/M-W= y1 y2 BY x(0 1)
/MISSING ANALYSIS.

Uji Mann-Whitney Kelompok NAC+antibiotik topikal dan Kelompok

antibiotik topikal

NPar Tests

Notes

Output Created 08-SEP-2023 10:57:00

Comments
C:\Users\CATURWARGA
COMPUTER\OneDrive\
Data
Documents\analisis dara dr
nabila res THT.sav
Active Dataset DataSet1
Input
Filter <none>
Weight <none>
Split File <none>
N of Rows in Working Data
40
File
User-defined missing values
Definition of Missing
are treated as missing.
Statistics for each test are
Missing Value Handling
based on all cases with valid
Cases Used
data for the variable(s) used
in that test.
NPAR TESTS
Syntax /M-W= y1 y2 BY x(0 1)
/MISSING ANALYSIS.
Processor Time 00:00:00,00

Resources Elapsed Time 00:00:00,00

Number of Cases Allowed a

98304

a. Based on availability of workspace memory.

[DataSet1] C:\Users\CATURWARGA COMPUTER\OneDrive\Documents\analisis dara dr

nabila res THT.sav

Mann-Whitney Test

Ranks

Kelompok N Mean Rank Sum of Ranks

 NAC+antibi
20 22.73 454.50
otik topikal

IL-8 pre Antibiotik

20 18.28 365.50
topikal

Total 40
NAC+antibi
20 14.15 283.00
otik topikal

IL-8 post Antibiotik

20 26.85 537.00
topikal

Total 40

Test Statisticsa

IL-8 pre IL-8 post

Mann-Whitney U 155.500 73.000

Wilcoxon W 365.500 283.000
Z -1.204 -3.436
Asymp. Sig. (2-tailed) .229 .001
Exact Sig. [2*(1-tailed Sig.)] .231b
.000b

a. Grouping Variable: Kelompok

b. Not corrected for ties.

NPAR TESTS
/WILCOXON=y3 WITH y4 (PAIRED)
/MISSING ANALYSIS.

Uji Wilcoxon Kelompok NAC+antibiotik topikal dan kelompok antibiotik

topikal

NPar Tests

Notes

Output Created 08-SEP-2023 10:59:10

Comments
 C:\Users\CATURWARGA
COMPUTER\OneDrive\
Data
Documents\analisis dara dr
nabila res THT.sav
Active Dataset DataSet1
Input
Filter <none>
Weight <none>
Split File <none>
N of Rows in Working Data
40
File
User-defined missing values
Definition of Missing
are treated as missing.
Statistics for each test are
Missing Value Handling
based on all cases with valid
Cases Used
data for the variable(s) used
in that test.
NPAR TESTS
/WILCOXON=y3 WITH y4
Syntax
(PAIRED)
/MISSING ANALYSIS.
Processor Time 00:00:00,00

Resources Elapsed Time 00:00:00,00

Number of Cases Allowed a

112347

a. Based on availability of workspace memory.

[DataSet1] C:\Users\CATURWARGA COMPUTER\OneDrive\Documents\analisis dara dr

nabila res THT.sav

Wilcoxon Signed Ranks Test

Ranks

N Mean Rank Sum of Ranks

IL-8 post NAC+antibiotik Negative Ranks 20a 10.50 210.00

 Positive Ranks 0b .00 .00
topikal - IL-8 pre
Ties 0c

NAC+antibiotik topikal
Total 20

a. IL-8 post NAC+antibiotik topikal < IL-8 pre NAC+antibiotik topikal

b. IL-8 post NAC+antibiotik topikal > IL-8 pre NAC+antibiotik topikal
c. IL-8 post NAC+antibiotik topikal = IL-8 pre NAC+antibiotik topikal

Test Statisticsa

IL-8 post
NAC+antibiotik
topikal - IL-8 pre
NAC+antibiotik
topikal

Z -3.920b
Asymp. Sig. (2-tailed) .000

a. Wilcoxon Signed Ranks Test

b. Based on positive ranks.

NPAR TESTS
/WILCOXON=y5 WITH y6 (PAIRED)
/MISSING ANALYSIS.

NPar Tests

Notes

Output Created 08-SEP-2023 10:59:37

Comments
Input Data C:\Users\CATURWARGA
COMPUTER\OneDrive\
Documents\analisis dara dr
nabila res THT.sav
 Active Dataset DataSet1
Filter <none>
Weight <none>
Split File <none>
N of Rows in Working Data
40
File
User-defined missing values
Definition of Missing
are treated as missing.
Statistics for each test are
Missing Value Handling
based on all cases with valid
Cases Used
data for the variable(s) used
in that test.
NPAR TESTS
/WILCOXON=y5 WITH y6
Syntax
(PAIRED)
/MISSING ANALYSIS.
Processor Time 00:00:00,00

Resources Elapsed Time 00:00:00,00

Number of Cases Allowed a

112347

a. Based on availability of workspace memory.

[DataSet1] C:\Users\CATURWARGA COMPUTER\OneDrive\Documents\analisis dara dr

nabila res THT.sav

Wilcoxon Signed Ranks Test

Ranks

N Mean Rank Sum of Ranks

Negative Ranks 16a 9.81 157.00

IL-8 post antibiotik topikal - Positive Ranks 4b

13.25 53.00
IL-8 pre antibiotik topikal Ties 0c

Total 20
a. IL-8 post antibiotik topikal < IL-8 pre antibiotik topikal
b. IL-8 post antibiotik topikal > IL-8 pre antibiotik topikal
c. IL-8 post antibiotik topikal = IL-8 pre antibiotik topikal

Test Statisticsa

IL-8 post
antibiotik topikal
- IL-8 pre
antibiotik topikal

Z -1.941b
Asymp. Sig. (2-tailed) .052

a. Wilcoxon Signed Ranks Test

b. Based on positive ranks.

NPAR TESTS
/M-W= y7 y8 BY x(0 1)
/MISSING ANALYSIS.

Notes

Output Created 08-SEP-2023 11:00:16

Comments
C:\Users\CATURWARGA
COMPUTER\OneDrive\
Data
Documents\analisis dara dr
nabila res THT.sav
Active Dataset DataSet1
Input
Filter <none>
Weight <none>
Split File <none>
N of Rows in Working Data
40
File
Missing Value Handling Definition of Missing User-defined missing values
are treated as missing.
 Statistics for each test are
based on all cases with valid
Cases Used
data for the variable(s) used
in that test.
NPAR TESTS
Syntax /M-W= y7 y8 BY x(0 1)
/MISSING ANALYSIS.
Processor Time 00:00:00,00

Resources Elapsed Time 00:00:00,01

Number of Cases Allowed a

98304

a. Based on availability of workspace memory.

NPAR TESTS
/M-W= z BY x(0 1)
/MISSING ANALYSIS.

Uji Mann-Whitney selisih IL-8 kelompok NAC+antibiotik topikal dan

kelompok antibiotik topikal

NPar Tests
Notes

Output Created 08-SEP-2023 11:01:18

Comments
C:\Users\CATURWARGA
COMPUTER\OneDrive\
Data
Documents\analisis dara dr
nabila res THT.sav
Active Dataset DataSet1
Input
Filter <none>
Weight <none>
Split File <none>
N of Rows in Working Data
40
File
Missing Value Handling Definition of Missing User-defined missing values
are treated as missing.
 Statistics for each test are
based on all cases with valid
Cases Used
data for the variable(s) used
in that test.
NPAR TESTS
Syntax /M-W= z BY x(0 1)
/MISSING ANALYSIS.
Processor Time 00:00:00,00

Resources Elapsed Time 00:00:00,00

Number of Cases Allowed a

112347

a. Based on availability of workspace memory.

[DataSet1] C:\Users\CATURWARGA COMPUTER\OneDrive\Documents\analisis dara dr

nabila res THT.sav

Mann-Whitney Test

Ranks

Kelompok N Mean Rank Sum of Ranks

NAC+antibi
20 30.40 608.00
otik topikal

z Antibiotik
20 10.60 212.00
topikal

Total 40

Test Statisticsa

Mann-Whitney U 2.000
Wilcoxon W 212.000
Z -5.356
Asymp. Sig. (2-tailed) .000
Exact Sig. [2*(1-tailed Sig.)] .000b

a. Grouping Variable: Kelompok

b. Not corrected for ties.
 Effect Size
Parameter Effect Size 95% CI
Cohen's D Lower Upper
IL-8 -1,36 -2,00 -0.72

Hubungan Usia dan IMT dengan IL-8

Correlations

IL-8 pre Usia IMT

Pearson Correlation 1 -.033 -.136

IL-8 pre Sig. (2-tailed) .841 .404

N 40 40 40
Pearson Correlation -.033 1 .093
Usia Sig. (2-tailed) .841 .570
N 40 40 40
Pearson Correlation -.136 .093 1

IMT Sig. (2-tailed) .404 .570

N 40 40 40

Hubungan jenis kelamin, riwayat merokok, lokasi lesi, dan derajat gangguan pendengaran
dengan IL-8

Jenis Kelamin
Group Statistics

Jenis Kelamin N Mean Std. Deviation Std. Error Mean

Pria 15 143.4420 48.01265 12.39681

IL-8 pre
Wanita 25 148.2844 71.11663 14.22333

Independent Samples Test

Levene's Test for t-test for Equality of Means

Equality of
Variances

F Sig. t df Sig. (2- Mean Std. Error 95% Confidence

tailed) Difference Difference Interval of the
Difference

Lower Upper
 Equal
variances 3.444 .071 -.233 38 .817 -4.84240 20.76805 -46.88511 37.20031
IL-8 assumed
pre Equal
-
variances not -.257 37.357 .799 -4.84240 18.86754 33.37453
43.05933
assumed

Riwayat Merokok

Group Statistics

Riwayat Merokok N Mean Std. Deviation Std. Error Mean

Tidak 27 134.2200 55.64432 10.70876

IL-8 pre
Ya 13 171.9077 71.24336 19.75935

Independent Samples Test

Levene's Test for t-test for Equality of Means

Equality of
Variances

F Sig. t df Sig. (2- Mean Std. Error 95% Confidence

tailed) Difference Difference Interval of the
Difference

Lower Upper

Equal
-
variances .760 .389 38 .075 -37.68769 20.59331 -79.37667 4.00129
1.830
IL-8 assumed
pre Equal
-
variances not 19.315 .110 -37.68769 22.47464 -84.67572 9.30033
1.677
assumed

Lokasi Lesi

Group Statistics

Lokasi Lesi N Mean Std. Deviation Std. Error Mean

IL-8 pre Unilateral 24 126.0283 40.14163 8.19388

 Bilateral 16 177.1288 78.20722 19.55181

Independent Samples Test

Levene's Test for t-test for Equality of Means

Equality of
Variances

F Sig. t df Sig. (2- Mean Std. Error 95% Confidence

tailed) Difference Difference Interval of the
Difference

Lower Upper

Equal
-
variances 14.331 .001 -2.719 38 .010 -51.10042 18.79064 -13.06075
89.14009
IL-8 assumed
pre Equal
-
variances not -2.410 20.323 .026 -51.10042 21.19936 -6.92432
95.27651
assumed

Derajat Gangguan Pendengaran

Group Statistics

Derajat Gangguan N Mean Std. Deviation Std. Error Mean

Pendengaran

Ringan 25 138.1892 52.02044 10.40409

IL-8 pre
Sedang 15 160.2673 77.62447 20.04255

Independent Samples Test

Levene's Test for t-test for Equality of Means

Equality of
Variances

F Sig. t df Sig. (2- Mean Std. Error 95% Confidence

tailed) Difference Difference Interval of the
Difference

Lower Upper
 Equal
-
variances 3.520 .068 -1.078 38 .288 -22.07813 20.47196 19.36519
63.52146
IL-8 assumed
pre Equal
-
variances not -.978 21.645 .339 -22.07813 22.58205 24.79877
68.95504
assumed