‫‪May 2021‬‬

‫مالحظه‬
‫*** يعني مو متاكده من االجابه‬
‫اسئلة ملف ‪ prometric‬مهمه تتكرر بالنص ارجعوا للملف‬
‫رسمة القلب مهمه كل اختبار تجي ‪ +‬رسمة االسهم ‪+‬رسمة المالريا‬

‫‪1‬‬

‫‪ 1‬اللهم انفعنا بعلمنا و زدنا علما ‪ ،‬دعواتكم‪.‬‬

 ‫ و‬reluctant inj and tab ‫ وكاتب انه‬erectile dysfunction ‫ فيه سؤال عن واحد صحته كويسه بس حصله‬-1
reluctant ‫المريض رافض‬
A)erectile vacuum(‫)ضعف االنتصاب‬

B) sildenafile(‫)سيلدينافيل‬
، ‫االنتصاب‬ ‫ويستخدم في عالج المشاكل الجنسية الوظيفية مثل الضعف الجنسي وضعف‬

drug a
Miosis +relieve pain
Drug b
Mydriasis + withdrawal symptoms
Drug c

morphine>naloxone>methadone

-Drug A
Pinpoint pupil + dizziness
Drug B
Mydriasis +withdrawal symptoms
Drug C
Withdrawal symptoms

-Morphine / naloxone / pentazocine

Morphine / naltrexone/codeine
morphine/naloxone/ caffeine

3-case pt with pneumonia and take antibiotic in 3day symptome remove , what the medical
intervention :
-stope all drug
-give oral ceftriaxone and oral azithromycin
-give oral ceftriaxone in 3 day and stop azithromycin

4- case pediatric patient 3 years with otitis media ? (‫ سنوات مع التهاب األذن الوسطى؟‬3 ‫حالة مريض األطفال‬
treat(high amoxicillin dose , azithromycin)
(Duration of treatment)
Mild to moderate: 5-7 days
Severe: 10 days
1
5- neonate 39 day has otitis media best ttt ?
Azithromycin
‫‏‬High amoxicillin dose

6- chlorothiazide (mechanism of action) ?(‫)الية عمل الكلورثيازيد‬

inhibiting reabsorption of sodium (Na+) and chloride (Cl−) ions from the distal convoluted
tubules(‫( تثبيط إعادة امتصاص أيونات الصوديوم‬Na +) ‫( وكلوريد‬Cl−) (‫من األنابيب الملتفة البعيدة‬

7-Pt have renal failure and dr. write sodium polystyrene sulfonate.pt asked about the
drug ?
.)‫ مع أيونات البوتاسيوم في األمعاء (خاصة األمعاء الغليظة‬،‫ عن طريق تبادل أيونات الصوديوم‬،‫دواء يقوم بالتخلص من البوتاسيوم‬
to increase serm conc of ca
to decrease serum conc of ca-‫‏‬
to to increase serum k-‫‏‬
to decrease serum k-‫‏‬

8-Pt women have osteoporosis and she take ca / vit D ,she want to treat osteoporosis what the
next teat (step) you give pt?
alendrant
.‫ هو دواء بيسفوسفونات يستخدم لهشاشة العظام وأمراض عظام أخرى‬.‫صوديوم األلندرونيت يباع على شكل دواء (فوساماكس) من شركة ميرك‬
‫د‬+‫ وحدة) ليصبح باسم (فوساماكس‬5600 ‫ وحدة أو‬2800( ‫)يباع الدواء وحده أو يضاف عليه فيتامين د‬.alendrinate

9-prophylaxis for breast cancer ? (‫)الوقاية من سرطان الثدي‬

‫‏‬-vit d
‫‏‬-vit A
‫‏‬Vit d and vit A
Prophylaxis of breast cancer: Raloxifene‫ ال سيم‍‍ا اللواتي‬،‫ لدى النساء بعد انقطاع الطمث‬،‫الوقاية من اإلصابة بسرطان الثدي‬
‫ي‍‍عانين من هشاشة العظام أو أكثر عرضة لإلصابة بسرطان الثدي‬.
Supplement decrease the risk of breast cancer: Vit D

2
10- affinity curve ?

Pt girl has diabetic disease she takes medication and one time she misses to take , what do
you do for her?
‫جايب كيس لبنت عندها سكر وبتاخد جرعه وتفوت جرعه‬ .
advice her take his medication as prescribed
engage her with a plan and schedule her medication-‫‏‬

12.patient has liver cirrhosis and complaint from epigastric pain was taking erythromycin
and propranolol, The dr prescribe him omeprazole for the epigastric pain ‫‏‬What is the best
describes the stability of drugs
-propranol will escape from first pass effect
‫‏‬-erthromycin will undergo acid hydrolysis

13.‫‏‬-patient has arthritis, take paracetamol and ibuprofen and his stool was black
Why :
3
drug drug interaction
‫‏‬-due to paracetamol
‫‏‬-due to gastric bleeding caused by ibuprofen *
‫‏‬-due to gastric bleed by paracetamol

14. Woman was taking a drug for migraine,she complained that her lactation was not
sufficient .
What is medication she is taken for migraine
-propranol ‫الصداع النصفي لدى األطفال‬
‫‏‬-ergotamin ‫ الباراسيتامول‬:‫( ويُستعمل فقط في حال أن األدوية المخففة لأللم مثل‬Paracetamol) ‫لم تُخفف األلم بصورة كافية‬.
‫‏‬-asprin
-Acetaminophen (can be use in lactation)‫بهدف التخفيف من األلم الذي يتراوح بين المعتدل إلى الشديد‬،

15.Patient with history of asthma nees ttt of open angle glaucoma

pilocarpine
‫‏‬-timolol
‫‏‬-lanatoprost ‫ التانوبروست يباع تحت المسمى التجاري " زاالتان‬Xalatan " ‫ كالزرق المفتوح الزاوية و ارتفاع‬،‫والذي يستخدم لعالج زيادة ضغط العين‬
‫الضغط البصري‬،

16. ‫ انزيم‬HMGCOA REDUCTASE ‫مسؤول عن خروج ماده ايه‬

(Mevalonate )

Pt have hypertension and she take regular treatment of drug but she observe orthrostatic
hypotension which drug make advers effect?

isosorbid mononitrate

4
propranolol-
hydralazine-

18. renal faliure and low alb and was prescribed phenytoin 300 mg
What is the important monitoring in this case :
-level of free phenytoin
‫‏‬-serum level of phenytoin
‫‏‬-trough level of phenytoin

19. Stewardship antimicrobial program is concerned with

antimicrobial resistance *

20. target of Hb in patient has renal failure

-111 g/L*
- 117 g/L
- 120 g/L
The target Hb we should achieve is >10 g/dl in dialysis patients

Pt ask about antibiotic used topical ointment in MARSA infection

vancomycin oint-
mupirocin oint-

22. Rare exposure :

cohort

23. Rare outcomes :

case control study

‫ مخصص النهي نوع من االدويه (او اي نوع من الكيمو ثيرابي لو‬vertical laminar flow ‫كان بيسأل عن ال‬ .24
)‫جالك‬

5
25. Adverse effect of doxurobicin is what :
-bone marrow SUPPRESSION
-cardiac toxicity

common = bone marrow suppression

most dangerous= Cardio toxicity

26. diabetic patient with hypertension and dislipidemia was ordered to take asprine 81 and
bisoprolol 5 mg and lisinopril 20 and atrovastatine 40 and metformine 1 gm , what is the
medication error the doctor made?
-two drugs are with wrong dose
-one drug is prescribed with wrong dose
‫توفر خيار المنجمنت غير صحيح فبيكون هو الجواب الصح ولم يتوفر بيكون باللون االحمر الخيار الصح‬
Pt 76 male new diagnosed with AF he discharge on aspirin 81 .bisoprolol 5, atorvastatin 40
,metformin 1000 bid ,lisno 20mg , dr dascis before pt discharge
-all treatment good
-rong management (‫)توفر الخيار بيكون هو صح وما كان متوفر بيكون صح باللون االحمر‬
Rong dose and rong drug
Rong two dose and rong two drug

Pt history of harte flower and gout . pt takes colchicine medicine when he takes the drug and
feels acute flaring with severe pain .what you give for pt to replace a drug:?
ibuprofen-
indomethacin-

28. Volatile liquid alkaloid

Nicotine
Theophylline

intrathecal ‫ مش‬iv ‫ علشان هو بيتاخد‬mini bags ‫ بيتاخد في‬vincristine ‫السؤال بتاع ال‬ .29
dispense drug in piggyback
Vincristine on auxliliry lable
Only iv push
Fetal if intrathecal , only iv push
Drug treatment in solid tumors?
Paclitaxel vincristin
6
 mcv ‫جالي نوع االنيميا ايه علي حسب نسبة الهيموجلوبين و ال‬ .30

31. Making powder into homogenous particles with adding water during process
A. Trituration***
B. Milling
C. Levigation
D ‫مش فاكرها‬

: ‫ رسمة القلب‬.32

7
 t1/2 ‫ والمطلوب اي دواء اعلي‬curve time against plasma conc. 33

‫ ماهي الزمرة المسؤله عن فعالية الدواء‬Ziduvodin - 34

OH

if take aspirin and ibuprofen ,what is the effect

Bleeding

sensitive ‫ اكتر وحده‬media‫ رسمة ال‬-36

37- Vitamin b12 name?

Cobalamin

38- Antidote digoxine?

Digifab

8
39- Herbs mimic domperdione?
ginger

40-B3 block which one?

Adrenergic antagonist

41- Patient take doxorubicin ?

MUST DO ECG

42- function of Isomer?

Same molecular formula but different functional group

43- Calculate absolute bioavailability?

44- Calculation phenytoin correction?

45- Patient take fingolimod ? ECG

46- Vaccine for Haj?

Meningococcal +Influenza

9
47-Picture malaria?

48- Calculation total body clearness?

‫ للزباين بتوع الصيدليه فيما يخص‬survey ‫ مشرف صيدلية كان عايز يقيم الصيادله اللي شغالين من خالل أنه يعمل‬-49
survey ‫ السؤال كان ايه انهي حاجه المشرف يركز عليها ف ال‬... OTC ‫موضوع صرف األدوية ال‬
-The pharmacist supervisor evaluates the working in pharmacy survey and makes a question
for the customer in otc .. which question is needed in sarvy??
-medical knowledge of pharmacist about OTC medication
-pharmacist responsiveness to their questions *
- the personal appearance of pharmacist
-the tone of his voice

50- Which alkaloid is used in rheumatoid arthritis pain ?

A. Hyoscine
B. Ricin
C. Capsaicine*
D. ‫مش فاكره‬

... ‫ بتاع االدويه المره‬taste ‫ (معرفش ده ايه) يستخدم في انه بيغطي علي ال‬balibalon ‫ كيس تانيه برضو بتقول‬-51
balibalon‫فايه هو ال‬
Cas about balibalone use to cover bitter taste drug , what is the balibine ??
-resin *
-resin alcohol

10
-‫مش فاكر باقي االختيارات‬

51- Case summary someone with hypertension need to adjust diet :

A. Decrease diet with cl
B. Increase diet with cl
C. Decrease diet with k
D. Increase diet with k*

52- Case summary someone taking warfarin what will the pharmacist counsel him :
A avoid leafy green food *
B increase leafy green food
C. Decrease leafy green food*
D. It doesn't affect warfarin at all

53- Medications need renal dose adjustment :

A. Tazocin and lincomycin
B. Lincomycin and vancomycin
C. Vancomycin and linzolid
D. Vancomycin and tazocin

54- ‫جالي كيس فيها شخص عنده حساسيه من البنسلين وبيسأل من مين االستركتشرات دي ال يستخدم معاه‬
‫ فطبعا بتدور علي اي حاجه فيها‬beta lactam ring

55- Fat acid ‫? وين بتصنع‬

Liver*
Pancreas.....etc

11
‫‪ -56‬خدت دواء من الكاونترال ‪nurse‬انتبهت الممرضه انو الدواء الفي العلبه ما لي للمريض لشخص آخر يعني اتصرف‬
‫غلط الممرضه خبرت كبيرة الممرضات انو الدواء غلط شو نوع‪error‬‬
‫)‪Unauthorized drug error (NOT SURE‬‬

‫?‪56- Beta 3 agonist‬‬

‫* ‪Merabigan‬‬

‫‪ -57‬ممرضه كانت جايبه من الصيدليه ادويه تقريبا كان ‪( ganisetron and methotrexate‬مش فاكر اوي) و حطاهم‬
‫في شنطه واحده و لما راحت للطبيب اكتشف ان ال ‪ label‬اللي علي الدوايين ‪ colorless‬فنبهت الطبيب ان المفروض‬
‫الميثوتريكسيت يكون ال ‪ label‬بتاعه اصفر ‪ ...‬ايه اللي المفروض يتعمل‬
‫‪separate methotrexate in another bag -‬‬
‫‪the labels must be differentiated-‬‬
‫‪-‬فيما معناه يعاقبوا الصيدلي ع الغلطه‬
‫ومش فاكر اخر اختيار‬

‫?‪58- Calculate Hepatic clearance‬‬

‫?‪59-Calculate Half life‬‬

‫?‪60-Calculate crcl‬‬

‫‪12‬‬
Child drank a full bottle of irone and showed psychological symptome:
-deferoxamine
-defroxamen + nasostagmane
Methotrexate antidote
lecoveran(fenolic acid)
Which drug can not give to neonates and infants?
Tetracycline
When will I stop mycophenolate if she wants to get pregnant?
Before 6 week
Pt did surgery and he wanted to lift the hospital ,which discharge vaccine should he give?
-mengintits
-influenza
-pneumococcal
Child has been having different appearing tics such as prolonged contracting muscles.which
being examined by experience type of extrapyramidal spasm ,which be beneficial in reducing
symptoms?
-benztropine(but if not in option put haloperidol)

Child 4 years suffer from diarrhea since two drug he diagnosed rotavirus ,what is
management?
-cyclover
-iv hydration
Ig in asthma pt and allergic reaction?
-IGE
Pt did dialysis and he took polystyrene ,why he took?
-decrease k
-decrease ca
-increase k
-increase ca
Which is the low molecular weight of heparin?
exnoprain

13
What will happen if you have an allergic reaction?
Secretion of histamine
What will induce secretion of the body?
-acetylcholine
HMG-COA potent enzyme inducer?
Rifampicin
Pt suffer from UTI and allergy of penicillin?
Ciprofloxacin or cephlexin
HIV treatment in general?

Nitrites side effect?

Nephrotoxicity
Aplastic anemia
Pt take abacavir then did HLAB 5701 and it was positive he suffers now abacavir side effect ,
what should be do to avoided?
-make HLA B 5701 before take drug
How can take vaccine?
-pt finished his treatment course
-neonatal
-pt with immunoglobuline*

14
15
27(doxorubicin)

61- Which of the following increases the warfarin effect

-zinc
-ginseng
-folic acid
-chromium

62-Dr ordered TPN for patients with severe hypo nutrition who didn't eat for long time.
This patient hasn't eaten for how long!?

- more than 7 days ***

-10 days
- 3 days

63- Which of the following can decrease the duration of a cold ? Vitamin c

64-ondansetron like?
16
a-ginger

65-woman take thyroxin for hypothyroidism became pregnant what to do take double dose
alendronate counselling?

a-take with a full cup of water 30 mins before breakfast and then sit for 30 mins

66- Cold products shouldn’t be given to children below ? 2 years

67-drug used in case of heparin induced thrombocytopenia ? -argatroban

68-rifampin side effect ? – change urine color to red (and other body fluids like tears)

69-ecg .. 2 questions about it .. that’s what you should know to answer them:

Qrs ..ventricular depolarization

T wave ..ventricular repolarization
P wave ... atrial depolarization
Qt .. ventricular action potential
Pr .. av conduction
St .. interval between ventricular depolarization and repolarization

17
70-
This Drawing was in the test and I was asked about drug which drug is C

71-Picture of antibiotic sensitivity? Largest circle

72-medical rep offers a sample ? Keep outside formulator

73- Woman with DVT, what is the most contraindicated contraceptive method?
Dermal patch (Because it contains Estrogen)

74-structure of how to convert this product to a selective norepinephrine reuptake

inhibitor ? – hydrolysis of N group

75-case about one using two drugs of cancer .. one with less side effect to choose ..what is
cost ? – cost effectiveness

76-vaccination case .. he came for you to take mmr vaccine ..history of taking
immunoglobulin for hep a last month what to do ? (Give after 6 months) (Vaccine ok to
give together but IG interferes with vaccine)

77-antidote of dabigatran? Idarucizumab

78-corrected phenytoin

18
79-what cause agranulocytosis? – clazoapine (imp) Anti thyroid ‫كمان تسويها‬

80-case about a girl has no dm but his sister has diabete type 1 .. what is the risk that can she develop d.m ? –

family risk(hostiore)

81-Pseudomonas aeruginosa is a? gram-negative bacilli

82-graph with toxic dose and effective dose ..calculate therapeutic index

83- Neuropathy and DM? Pregabalin

84- Clearance = Vd x ke , Vd= dose/conc.

85- Patient taking Warfarin but drinking herbal tea that is decreasing effect, what is the tea? Green Tea

86- Patients want to take non-Sedating antihistamine?

19
Second generation of antihistamines (Fexofenadine, Loratadine, Cetirizine etc)

87- Patient ate nuts, type of sensitivity? Immediate sensitivity type 1 by

88- case deep wound + unknown history? Tetanus vaccine+Tetanus Immunoglobulin.

89- case NOT deep wound + unknown history? Tetanus vaccine only

90- Gives lab results with a positive Dangroff’s test, what does it contain? Alkaloids.

91- Iron Antidote? Deferoxamine

92- Pt with DM and dyslipidemia? STATIN

93- Old woman has difficulty in voiding, what to give? Oxybutynin

94- Immediate antidote for Cholinergic toxicity? (like Tear gas) Atropine

20
95-Contraindicated in ejection fraction HF? Pioglitazone (most glucose transporter inhibitors)

100- Increase mypathy whenever used with statin? Gemfibrozil

101- Clopidogrel Cytochrome for activation? 2C19 which is inhibited by Omeprazole

102- Sildenafil counseling? Talk with him in a private area.

103- Give the wrong drug to the patient who to contact when you find out first?The Patient.

104- Inducers and inhibitors of Warfarin effect.

21
105- Methotrexate Antidote? Folic acid (or Folinic acid or Leucovorin)

106- Usp 795? Non sterile

107- Usp 797? Sterile

108- Patients don’t want to take Diabetes medication because they are scared of being Fat?

Make him understand the importance of medication.

109- Antiplatelet Contraindicated in patients with transient ischemic attack? Prasugrel.

110- Doctor calls pharmacist for trails about AF which site ? up to date

111- Calcium salt for injection? Calcium Gluconate

112- w/w elimination rate?

113- Structure of CCB which one is dihydropyridine?

22
114- Acute gout attack? Colchicine

115- TB Drugs with Eye vision side effects? Ethambutol

116- Herbal for physical endurance? Ginseng

117- Drug Undergoes extensive first pass metabolism? Propranolol

118- High risk? PRN

119- Are (X and Y structures) Enantiomers, Diastereoisomers, Epimers or Dimers.

23
24
120- Take 1 tab BID? 1 tablet twice daily.

121-HCG+ ( Means a pregnant woman) what drug is safe to use? Levothyroxine

122- BMI Calculation

123- Tmax Calculation

25
124- Clearance calculations

125- Multiple Creatinine clearance calculations with a lot of different units of measurement

126- Which lymphocytes are responsible for cell mediated immunity?

T lymphocytes

127- Norepinephrine is? Neurotransmitter and hormone

128- Phospholipid composed of : Phospholipids are amphiphilic

129- molecules composed of a glycerol backbone carrying a

hydrophilic polar head group and two hydrophobic fatty acyl tails

130-best choice of constipation drug for chronic constipation? Psyllium (bulk laxative)

131- Red book> for narcotics

26
Meyler’s > side effects

132- There were some lab results with a question about whether they were because of:

A- Kidney failure B- something called “Refeeding Syndrome”

133-Question about angry patient: Listen to him calmly and then answer quietly

134- Question about old man abusing his wife’s meds and what is the mistake pharmacist did:

A- Self Diagnose him as an alprazolam abuser

B- Breaching patient confidentiality

C- Typing in his notes that he abuses Alprazolam (I choose A)

135- Who is responsible for Drug shortage or approving drugs? SFDA

136- Lice treatment? Permethrin

137- Question about treating Menstural pain with structures? I choose Diclofenac structure but not sure

(There was no Ibuprofen)

27
138-Pharmacophore definition?

a part of a molecular structure that is responsible for a particular biological or pharmacological action.

139- Bioequivalence Calculation

140- 1gtt uo BID? One drop in both eyes twice daily

141- Diabetic pt has has stabbing pain and burning •Gabpentin (Diabetic neuropathy)

142-Someone who is planning to be an owner of a pharmacy in Saudi Arabia. Which of the following laws

and regulations should be applied, If he can’t get enough Saudi pharmacists can he open a pharmacy?

-owner must be saudi certificate pharmacist

-owner must be non-saudi but must assign asaudi pharmacist as executive pharmacy manager.

-owner should be saudi and can hire non saudi.

-under some rules

28
143- has (sugar part ) and (non-sugar part)? Glycoside

144- Enzyme hydrolyze triglycerides (fats) into their component fatty acid and glycerol molecules?

Pancreatic Lipase

145- Photo of reaction and resulting in + 58 Kjol? Endorgenic.

Exergonic: An exergonic reaction is a chemical reaction the free energy is negative. Endergonic reaction nonspontaneous

reaction or an unfavorable reaction) is a chemical reaction free energy is positive. Exothermic reactions are reactions or

processes that release energy, usually in the form of heat or light

146-Two different configurations of a molecule and asking why is this good? Flexibility

147-Bentonite (Veegum)? suspending agent

148- which of the following drugs at high dose can induce hepatotoxicity by producing a
phase I cytotoxic metabolite?
A.Meloxicam
B.Galantamine
C.Paracetamol
D.Desipramine **

149- Which one of the following reflects nutritional status over the previous week and so
it helps predict the response to parenteral nutrition?
A.Albumin
B.Pre-albumin
C.Transferrin
D.Retinol

150- USP 797 was developed to

(A) decrease microbial contamination of
compounded sterile preparations.
(B) ensure the proper use of aseptic technique during
the manufacturing of sterile preparations.
29
(C) prevent harm to patients, including death.
(D) decrease unintended physical and chemical
contaminates found in compounded sterile preparations.
A or B
A

151- Smoker patient (consuming 3 packets a day) with a history of schizophrenia was on
haloperidol, then the patient developed extrapyramidal side effects (EPS) and the

✅
physician wants to change his medication, which one is safest?
A.Aripiprazole
B.Clozapine
C.Olanzapine
D.Ziprasidone

152- MN a 49 -year-old woman with a history of ischemic heart disease presents with
severe pain in small joints because of rheumatoid arthritis. She also has a history of
epigastric burning in the past, relieved by OTC PPI. Her medications include bisoprolol
5mg mg once daily, aspirin 81 mg/day, and rosuvastatin 5 mg/day. Her joint pain is not
relieved by paracetamol 500 mg 4 times a day. Her physician wants to initiate
nonsteroidal anti-inflammatory drug (NSAID) for her; however, the primary care provider
is worried about potential gastrointestinal (GI) toxicity. Which regimen is best for treating
this patient's pain while minimizing the risk of Gl toxicity?

✅
A.Celecoxib 400 mg with omeprazole 20 mg twice daily.
B.Naproxen 500 mg twice daily plus omeprazole 20 mg/day.
C.Paracetamol 1 gram 4 times a day
D.Piroxicam 20 mg/day plus antacid suspension three times daily

153-A 26-year-old female is taking interferon-beta la 30-mcg intramuscular once weekly

to treat relapsing-remitting multiple sclerosis (RRMS). She has not had a clinical relapse
in 12 months. This is her first experience with immunomodulatory therapy. She recently
received a diagnosis of mild depression and was started on paroxetine 20 mg once daily.
Which one of the following is best to recommend for this patient's DMT?

A.Remain on current therapy ✅

B.Change to glatiramer acetate 20 mg subcutaneous once daily
C.Increase paroxetine to 40 mg orally once daily
D.Change to dimethyl fumarate 240 mg orally twice daily
30
154-A patient (weight 65 kg) is receiving PN after abdominal surgery. The PN contains
about 1600 kcal, including 100 g of protein, 500 kcal as lipid, and 200 g of dextrose. The
following additives are also included in a 24-hour infusion of PN: sodium chloride 50
mEq, sodium acetate 100 mEg, potassium acetate 60 mEg, sodium phosphate 30 mmol,
magnesium sulfate 12 mEq, calcium gluconate 10 mEg/day, multivitamins 10 mL, and
several trace elements 3 mL. After 48 hours of PN, the patient has developed metabolic
alkalosis and laboratory values as follow:
Na+ 140 mEq/L (Normal).
K+ 3.8 mEq/L(Normal).
Cl- 92mEq/L(Low),
serum bicarbonate 35 mEq/L(High),
pH 7.6(High).
PCO2 47 mm Hg(High), and bicarbonate 36 mEg/L(High). Which adjustment to the PN
formula is best at this time?
A.Increase lipids to provide 750 kcal and reduce dextrose to 130 g.
B.Increase sodium acetate to 150 mEg/day and discontinue sodium chloride.
C.Increase sodium chloride to 150 mEq/day and discontinue sodium acetate.
D.Add sodium bicarbonate 50 mEq to PN.

155-Large volume of distribution (Vd) indicates extensive tissue binding of the drug and
less free drug in the plasma to be dialyzed. Which one of the following drugs is expected
to have a high Vd and not to be highly dialyzed, ie., not removed from the body by
dialysis?
A.Aspirin
B.Digoxin
C.Gentamicin
D.Lithium

156-MA 67-year-old man with COPD has been using inhaled salbuterol 2 puffs four
times per day as needed. His symptoms have worsened during the past year, and now he
has persistent symptoms and shortness of breath, even while walking around his one-story
house. His mMRC dyspnoea score is 2 and CAT score is 10. His spirometry shows a
FEV1 of 70% of predicted and FEVV FVC ratio of 60% of predicted. He has had no
previous COPD exacerbations. Which medication is best to initiate for MA in?
A.Inhaled fluticasone.
B.Inhaled fluticasone/salmeterol.
C.Inhaled tiotropium
31
D.Oral roflumilast

157-patient with deep vein thrombosis (DVT) was treated with 5 mg/day of warfarin. She
was compliant and had no other medications, denied the use of vitamins and herbal
supplements, and the amount of vitaminK in her diet was stable. Which one of the
following pharmacogenetic testing would best explain the patient's response to warfarin
therapy?
A.CYP2C9 genotype is *3/*3
B.CYP2C19 genotype is *2/*3
C.VKORC1 genotype is AA
D.VKORC1 genotype is BC

158-In the management of multiple sclerosis (MS), which of the following is considered a
highly active disease modifying agent?
A.Interferon Beta-1a
B.Glatiramer acetate
C.Interferon Beta-1b
D.Ocrelizumab

159-A patient who was admitted for liver transplant. Before transplant, she was found to
be infected with HCV genotype 1b. What is the target genotype will be helpful in
treatment of this patient?
A.L28B
B.INFL2
C.IL17A
D.IL36RN

Antidepressant help to stop smoking

‫فين‬
Bupropion

Pt have a gout and take colchicine he feels adverse symptoms and feels an acute flaring
gout with severe pain ,he asks if have another treatment to replace it?

Ibuprofen-
Indomethacin

162- Breastfeeding is contradicted with ?

32
Aspirin , ibuprofen

163- contraindication in (pregnancy or lactation can’t remember)

A. Acyclovir
B. piroxicam
C. Meloxicam
Doxycycline ***

164-Patient needs anticoagulant for dvt after surgery?

6 month , 12month , 9 month. , 3 month

165- Dr
prescribed anti-seizure for patient for child 3000 mg iv and had
dehydration, dizziness and asked for what type of error ?
Commission error,
omission error
, administration error
, whole medication process error
Monitor vancomycin by ?
Trough level,
peak level
, standing test

166- In maternal multivitamin which is main focus?

Vitamin b12, pyroxidine b6 , folic acid ***

167- Planning for mid to long term ?

Operational statement,
mission statement
, vision statement,***

168- Patient with gp6 deficiency and has uti ?

Nitrofurantoin ,
cephalosporins
ciprofloxacin,
tmx-sulf

169- Which required medium risk for preparation?

33
Iv fluid, omeprazole suspension, eye drops***

170- How to decrease confounding ?

Double blinding
, increase sample size

171 To interpret thyroid function by?

T4
tsh
growth hormone

172- part of immunoglobulin attached to B-cell?

light chain,
heavy chain,
immunoglobulin fold (fc)

173-Pharmacist communicate with other pharmacists through email?

Fine as long between healthcare workers,
Remove patient's name and only inr,
should noy be discussed by email,
include patient with conversations

174- new drug that has excellent effects in decreasing death rate associated with highly
fatal disease , how will that drug affect the disease rate ?
1. Prevalence will be increased
2. Prevalence Will Be Decreased
3. Incidence will be decreased
4. Incidence will be increase

175-Complications of parenteral nutrition and lab results showed high liver enzymes ?
1.Liver cirrhosis
2.Liver cholestasis
3.Pancreatitis
4.Cholestasis

34
 : ‫ ستركشرات‬-176
‫ وتكرر السؤال باكثر من طريقة غير‬second generation ‫ ويسال اي واحد فيهم راح يكون و‬antihistamine‫‏‬
‫االستركشر‬
‫البينزودايزيبام حدد اي واحد منهم يكون من العايلة ذي‬

177-Hypertension with dm best choice ? ACE

178-Hypertension with black patient? CCB

179-Antidotes
For warfarin Phytonadione (Vitamin K1)
For heparin Protamine sulfate
For iron Deferoxamine mesylate
For paracetamol Acetylcysteine
Rivaroxaban Andexanet alfa

180- Equivalent dose methylprednisolone equivalent to prednisone

‫ سؤال لمين ترجع اذا شفت احد يعلن معلومات غلط عن ادوية تبلغ اي جهة بالضبط خيارات منها وزارة‬-181
***SFDA ‫االعالم او وزارة الصحة او الهيئة او ترجع تتواصل مع الشخص ذا وتعلمه‬
pharmacokinetics ‫ مو‬clinical pharmacokinetic ‫تعريف‬

35
182- Toxicokinetics
refers to the study of absorption, distribution, metabolism/biotransformation,
and excretion (ADME) of toxicants/xenobiotics in relation to time.

183- What’s the best preventive measure for COVID-19?

- wear a surgical mask
- wear n95 mask
- wear gloves
- wash hands

The Doctor asked the pharmacist about a drug of diuretic with HF diseases ,he asked
where they find new study information about it?
Uptodate
Pubmed

Dr wirt for baby cortisone ointment and want mitigation ?

‫ ويطلب منك كصيدلي انو تسويله تخفيف مع‬%1 ‫الدكتور كتب لطفل اظن مرهم كورتيزون‬
‫ اعتقد‬soft paraffin

combination ‫ اتوقع ايش تبدا معاه‬meningitis ‫ كمان سألني واحد عنده‬-186

187- dose of ca
Man 1000
women1200

188- duration of treatment for osteomyelitis

The duration of therapy for acute osteomyelitis is 4-8 weeks.
but treatment is usually administered for a minimum of 6 weeks
36
189- three Q long case with lab result and cardic enzyme result and ask about diagnosis
(angina ، StEMi or NSTMi)
note: UA = unstable angina

190- five Q about vaccine

Pregnant take (Dtap, or HPV)
McV4 in child (1'3'6'9 month)
Vaccine prevent cervic cancer
Man want to travel which vaccine take Hep A

191- What is normal QT interval time?

- 0.4
- 0.04
-4
- 44 seconds

192- S1's2 sounds in heart Indicate what?

S1 is normally a single sound because mitral and tricuspid valve closure occurs almost
simultaneously. Clinically S1 corresponds to the pulse. The second heart sound (S2)
represents closure of the semilunar (aortic and pulmonary) valves (point d).

37
193- Lub .dub
The "lub" sound is produced by the closure of the AV (mitral
and tricuspid) valves. When the ventricles relax, the BP
frops below that in the artery, and semilunar valves (aortic
and pulmonary) close, producing the "dub" sound.
‫الصوت ده بنسمعه واحنا حاطين السماعه علي القلب‬
Indicate what ??
‫االختيارت مش فاكرها‬
‫بس كلها اشياء عاديه زي ده صوت مثال نقل الدم‬
‫ماعدا خيار واحد‬
‫ انها توحي بوجود‬disease

194- Irreversible s.e of aminoglycoside

Nephrotoxic
Ototoxic

195- Contraindication Of fibrinolytics

‫من ضمن االختيارات‬
Pregnancy
Stroke
Ischemia 2 month ago
Cardiovascular risk
Need ti be asses before using statin
‫كان كلها حاجات قلب‬
‫ماعدا خيار واحد‬
Diabetes

196- Used on ttt of fistula crohn's disease

‫ممكن انا كاتبه غلط‬
‫بس نوع زي ده يعني‬
Infliximab
Sulfasalazine
‫مش فاكر باقي االختيارات‬

t1/2‫ عشان يزودا ال‬polyethylene glycol ‫ ااه مركب ضافو ليه‬-197

peg‫ايه فايده ال‬
‫من ضمن االختيارات‬
38
 ‫انه بيزود حجم المركب‬
‫مش فاكر باقي االختيارات‬
‫واالختيارات مش فيها انه يزود ال‪t1/2‬‬
‫‪Increase duration‬‬

‫‪-‬اي الدوا اللي من اثاره الجانبيه‪198‬‬

‫‪Progressive multifocal‬‬
‫‪Natalizumab‬‬

‫‪39‬‬
199- cromlyn is
Mast cell stabilizer***
Vasodilator
leukotriene receptor antagonists
‫وخيار ناسيه‬

40
200- What dosage form should be refrigerated regardless of its content? Suppositories
(my ans) , Eye Drops, Oral Solutions

201- Effect of phenobarbital on TCA? Decrease con by increasing metabolism

202- Role of grape seeds ? antioxidant

Ondadnserton=ginger
Cyclophosphamide toxicity = hemorrhagic cystitis
HMG-CoA reductase= at the night(statain)
Valin deficiency cause =Valinemia is a very rare metabolic disorder. It is
characterized by elevated levels of the amino acid valine in the blood and urine
caused by a deficiency of the enzyme valine transaminase. This enzyme is
needed in the breakdown (metabolism) of valine.

Furosemide : Spironolactone (40 : 100)

Use of cranberry juice: UTI

Dry cough: Thyme

Natural products for hyperlipidemia:

Garlic , red yeast rice , Fish oil

Neonate with ductus arteries: Indomethacin

Q- In cough what is the enzyme ? Bradykinin

One came to you in the pharmacy and told you she opened the eye drop 45 days ago what
should she do?
Discard the medication ( expiry date 28 days after open)

Q- Most sensitive and specific test for myocardial damage? Troponin

Pre diabetes: modify life style

Amiodarone and warfarin: avoid green...

41
‫‏‬Sickle cell pain crises ? Morphine

‫‏‬Which of the following is physical examination? Percussion

‫‏‬Diphtheria caused by ? Corynebacterium

‫‏‬Enzyme breaks starch? Amylase

‫‏‬thyroid monitoring ? 4-6 weeks

‫ ‏‬acilitated Diffusion Definition ?

F
‫‏‬Facilitated diffusion is a form of facilitated transport involving the passive movement
of molecules along their concentration gradient, guided by the presence of another
molecule – usually an integral membrane protein forming a pore or channel

First line malaria

Antifungal need renal adjustment? Fluconazole

Wich drug are natural drug ?Digoxin
-‫‏‬- child 5 years old present to take dtap & MMR
‫‏‬But he is now on prednisone and antibiotic for 5 days

-‫ ‏‬antiepileptic medication for. Pregnant women?

- ‫كان في سؤال اي من االدويه التالية يسبب للطفل نعاس وخمول بسبب ان االم كانت تاخذه بالترايمستر الثالث؟‬
‫‏‬- which of the following used in preparing TPN

‫‏‬Emulsion, suspension.. ‫تعريفهم والخصائص‬

‫‏‬- what to monitor in Atorvastatin? Liver function

42
‫ *‏‬what in Baseline and thereafter

43
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45
-‫ ‏‬what is the function of mitochondria?
‫‏‬- function of Golgi apparatus?
‫‏‬- you found the bacteria shape is long rods, what is the type? Bacillus
- ‫ كيسز مع الالب ريزلت لها ويقول وش نوع االنيميا؟‬٣ ‫جاب‬
‫‏‬- which of the following medications is contraindicated in G6PD deficiency?
‫‏‬- what to monitor prior starting digoxin
‫‏‬Emulsion, suspension.. ‫تعريفهم والخصائص‬
‫‏‬Obese: Bupropion
Lithium Toxicity: decreasing Na+ like (ACE-I, Diuretic)
Antiepileptic for pregnancy : Levetiracetam, lamotrigine
# Carbamazepine, Oxecarbamazapin, Phenytoin, Fosphenytoine: HLA-B 1502
Eclampsia: Mg sulfate
Start before pregnancy:
1 month: Folic acid (Vit B9): # To decrease risk of neural tube defect
Mycophenolate (immunosuppressant)
6 weeks in female , 12 weeks in male
Medication and prolactin level:
Glomerulus filter:
• Substate wt. < 40,000 can pass the filter # Mwt > 500 will excreted in biliary
‫‏‬Direct thrombin inhibitors: - Oral: dabigatran
Vit b12 Absorbed by intrinsic factor
Pulmonary Embolism (PE):
- LMWH (Enoxaparin, Daltaparin)
- UFH (Fondapanux)
Drug increase INR
46
Antidote
Apixaban, Rivaroxaban, edoxaban: Andexanet alfa (a)
> 60: pneumococcal disease vaccine
Deep wound + Unknown Vaccination history = Td + TIG
P wave: Atrium depolarization
QRS complex: Ventricular depolarization T wave: Ventricular Repolarization
Digoxin toxicity will be increased by: decrease K+, decrease Mg+, Renal failure
Acute Ischemia: Alteplase
Sun protective factor (SPF):
Simply:
Minutes after SPF (with sunscreen) SPF = ------------------------------------------------------ Minutes before SPF
(without sunscreen)

Plant origin (epipodophyllotoxin): Etoposide

Statin cause myopathy

After med. metabolism become: Polar

Cross the placenta %:

• Mwt < 500
• Lipophilic
• Non-ionized

Brown urine : nitrofurantoin

Dark feces : iron
Ethambutol treat TB and effect the vision

Prodrome: the signs and symptoms of toxicity syndrome

BPH treatment

Mesalazine treat and maintenance of: Ulcerative colitis Fistulas ulcerative colitis: infliximab

Acute migraine attack treatment

Cyproheptadine have a antihistaminic activity and 5- hydroxy-tryptamine (5-HT) antagonist “Serotonin

antagonist”

Furosemide : Spironolactone (40 : 100)

Use of cranberry juice: UTI

Dry cough: Thyme

Natural products for hyperlipidemia:

47
Garlic , red yeast rice , Fish oil

48
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Purine bases= Adennine....Guanine
Pyrimidine=Thymine....Cytosine
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98
200- What dosage form should be refrigerated regardless of its content? Suppositories
(my ans) , Eye Drops, Oral Solutions

201- Effect of phenobarbital on TCA? Decrease con by increasing metabolism

202- Role of grape seeds ? antioxidant

99
203- Gasping Syndrome in babies is caused by the administration of? Benzyl Alcohol

204- Many cases with lab data and you have to interpret the right intervention , syndrome
name, interaction like for example
o Low albumin level will result on high total phenytoin
o Low bicarbonate high serum creatine and BUN and patient was taking different
anti-diabetic drugs so what oral medication to stop: Metformin (my ans), Insulin,
Pioglitazone
o Hypophosphatemia and hypokalemia during TPN: Refeeding syndrome,renal failure,…
o Blood glucose readings (they were within the normal range and HBA1C is 6.8% patient
was taking 850mg metformin BID what to do with metformin? Increase, decrease or keep
the same dose or add gliclazide

205- PRN ? as needed

206- 1 gtt OU TID ? 1 drop in both eyes three times daily

207- Patient took omeprazole for 1 month without improvement: I chose refer the patient,
other choices include options like add cimetidine…

208- Which of the following is prepared in vertical laminar air flow : Chemotherapy my
answer was Doxorubicin

209- Why do we give vasopressin in septic shock? decrease epinephrine dose (my ans)or
increase MAP by increasing cardiac contractility and 2 other options

210- Maximum daily dose of paracetamol? 4g

211- B12 :? cyanocobalamin

212- Vitamin contraindicated in high dose sin pregnancy : Vitamin A

213- Basal insulin dose calculation for patient that has to take 0.5 U/kg of mixed insulin
his weight was 60 kg : I answered insulin glargine 15U once daily

214- Use Dompiredone for 3,7 (my ans),… days

215- Maximum amount dispensed for oral narcotics: 30 days

100
216- Maintenance dose of digoxin for elderly patient taking multiple drugs including
lisinopril and amiodarone: 62.5 mcg,125mcg,250mcg (my an 125mcg)

217- One statement is true about 5 alpha reductase inhibitors : cause orthostatic
hypotension, take 6 months till clinical benefit (my ans) is observed and other 2 choices

218- Error that results from unpredictable fluctuation in the measurement choices were
Bias , systemic, random, systematic error

219- You received a prescription on a plain paper what to do : tell the manager, talk to
prescriber and don’t dispense, talk to prescriber and dispense

220- Role of synthetase enzyme : I answered join 2 molecules using ATP

221- LH hormone is regulated by ? negative feedback (my ans), Positive feedback,

Diurnal feedback

222- How to increase patient adherence ? separate drugs , put them in one place, pill
box(my ans), let family members remind the patient

223- Long case but the summary is ferrous sulfate cause black stool and constipation

224- Heavy smokers have anemia due to: chronic smoking , GI bleeding (my ans) , ….

225- patient had cancer admitted to the hospital to do gastrostomy , he had severe weight
loss ? Chronic disease-related malnutrition , injury-related malnutrition,etc

226- which phenothiazine is used for its antihistamine property: chloropromazine,

promethazine(my answer) … etc

227- rate control drug contraindicated in HF : I answered verapamil

228- malaria picture and asked what drug to use ? Quinine

229-change quinine from R to S results in ? antiarrhythmic drug

230-pharmacoepidemiology, pharmacophore, cross-sectional study definition

101
231- loperamide structure with name and asked about its mechanism ? opioid agonist in
the intestine

232- benzodiazepine structure

233- which first generation antihistamine is a prodrug for second generation (structures
with names) Diphenhydramine,chlorphenerapmine, hydroxyzine, (I think the 4th answer
was acrivastine but not sure)

234- HTN patient with flu what to give ? Dicolfenac + diphenhydramine, Paracetamol+
xylometazoline, paracetamol+ pseudoephedrine

235- 23 years old asthmatic patient her vaccination history was ( influenza in october last
year and TDap vaccine last 7 years ) what vaccine to give when she has been admitted to
hospital in july of this year ? tetanus, influenza, pneumococcal

236- Snake bite with mild toxicity? give

Antivenom for snake And neostigmine for tachycardia

237- Atenolol antidote ? Glucagon

238- The purpose of phase 1 and 2 clinical trials

239- Amino acid cysteine forms which bond in 8.4 PH disulfide bond , H bond, ionic
bond,..

240- Safest BZDS for elderly? Lorazepam (my ans), Diazepam, Cholrodiazepoxide,..

241- What model or approach to use to change patient behavior on individual scale (can’t
recall exactly) but I chose Health belief model other options were ecological approach,
diffusion of innovation,

242- What cells to use to express glycoprotein in large scale ? E.coli, mammalian( my
ans), yeast, Mosquito

243- After Hajj seasons MOH have to send reports about diseases and deaths during al
Hajj to ? Ministry of Hajj, WHO, SFDA, CBAHS
102
244- Long case but the summary that Buspirone it’s the safest anxiolytic to be used with
morphine (lower risk of respiratory depression)

245- Patient information leaflet is also available in which resource (something like this)
AHFS Drug information, Micromedex, 2 other books names

246- Calculation of Bicarbonate w/w % if 2 g of bicarbonate requires 20 ml of water to

dissolve (no other given info except PH and bicarbonate level and I couldn’t the right
answer by cross multiplication /9.01%, 10.32%,5.65%,8. Something%

247- Female CrCl calculation?

248-Loading dose calculation?

249- Entameoba Histolytic treatment in pregnancy ? Know the dose also

Metronidazole 750mg q8h for 10 days
250- Treatment for acute Mania ? Lithium

251- Mood stabilizer agent used in Bipolar ? Lamotrigine

252- Plague is transmitted by ? fleas

253- Vaccination during hajj ? MCV

254- Hepatitis B mother gave birth to baby so what to do ? give Hepatitis B vaccine with
IG within 12 hours of birth

255- Patient is going to travel to hepatitis A pandemic country: I ans give Hepatitis A
vaccine with IG A

256- Which alcohol is used in USP? no 70% isopropanol in answers (65% isopropyl, 855
isopropyl,95% ethyl alcohol, ..etc)

257- USP 797 for sterile compounding

258-Pharmacotherapy Plan includes choices were like: o Safety, adherence, indication,

untreated indication
103
o Safety, effectiveness, untreated indication
o Safety, adherence, indication, body weight

259- Amiodarone increase warfarin level

260- Anticoagulant for patients with cancer: I chose Enoxaparin

261- IgE cause mast cells degranulation

262- Calculation each ml contains 1250U : patient has to receive 2500 U loading dose
then infusion of 400 U/h for 2 hours 300U/h for 2 hours then 200 U/h for 5 days calculate
the volume that should be dispensed to the patient

263- One Q about which type of cells recognize cancer cells that lost MHC1 antigens?
cytotoxic T cell, Natural killer, macrophage,…

264- Major Hisocompatiblity complex ? Human leukocyte antigen

265- Defective drug product we report it to ? MOH, SFDA,..

266- Parkinson patient has dry cough he was using Selegline MAOI but stopped it before
3 weeks what to do ?
o It is reasonable to give Dextromethorphan, give Guaifenecin, Don’t give
dextromethorphan

267- Disadvantage of modified unit dose ? more drug wastage, more meds errors, more
dispensing time, more storage space

268- Long case with lab data , patient had meningitis, he is 61 years old what empiric
therapy to give I chose Vancomycin, Ampicillin, Ceftriaxone

269- Patient with HTN and Left ventricular ejection fraction is less that 40% what to
give:? spironolactone (my ans), lisinopril,..

270- CHA2DS2VASC calculation?

271- The manager is production-oriented so he cares about : I answered increase

production efficiency
104
272- Aminophylline % in theophylline ? 70,75,85( my ans),90

273- Which of the following is absolute contraindication to enteral feeding ? Bowel

ischemia, pulmonary embolism, bowel ischemia

274- Patient entered ICU with acute kidney injury what to monitor ? Albumin:creatine
ratio, urine analysis, urine volume over 24h

275-Case of patient is taking vancomycin but its level in the blood is still low so what to
do? increase frequency of giving as it is time-dependent effect

276- Vancomycin cause? red man syndrome

277- 4 Curves, which one has highest bioavailability with lowest fluctuation on oral
dosing

278- Disadvantage of face-to-face communication: I chose interruption of clinic and

patients flow

279-First line for status epilepticus: Lorazepam (my ans), Phenytoin, Phenobarbital, etc..

280- HIV? is Retrovirus virus

281- HTN patient with DM what to give? ACEIs ( in my exam it was Lisinopril)or ARBs

282-B.P reading 150/75 ? Isolated HTN ( when systolic pressure is more than 130 and
diastolic pressure is less than 80 )

283- An important element when the physician does an interview with the patient (I can’t
recall it exactly) but I chose effective listening. Other choices include: close-ended
questions, interrupt patient,…

284-A strategy of setting prices primarily based on consumer’s perceived value ?

Value-based Pricing

285-Atomexetine enzyme ? CYP2D6

105
286-Primary prevention ? vaccination

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The explanation :

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‫* جا السوال بس بدون حمل‬

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287- case with hypotension, hr 140
best management ?
albumin, ringer's solutions, hypertonic solutions

288- drug associated with peptic ulcer?

omeprazole , ibuprofen, acetaminophen, Metrodiazole or meticlopromide ( not sure of
the last one )
138
289- used for VA and SVA?
(procainamide, sotalol, dofetilde)

290- used with caution in gout ?

( hydrocholothiazide, spirolactone )

291- high alert medication ? dextrose 50%

292-ibuprofen otc dose?

• Max dose OTC: 1200 mg
• Max dose Prescription: 3200 mg

293- nsaid structure with lowest gi risk ( both ibuprofen and celebrex are in choices)
structure without name

294- st.j with citalopram ?

serotonin syndrome

295-Q about TCA with 2 amin ? more NE selectivity

296- case about elderly with BPH and erectile dysfunction, treatment options
management was combination ( Sildenafil after 4 hr of tamsulosine , Tadalafil after 4 hr
of tamsulosine)?!

297- incidence calculation ?

298- a lot of cases including ab therapy ‫موجوده بالتجميعات‬

299-hydroxychloroquine toxicity se ? visual impairment

300- ortilast counseling?

301-Most effective in ttt +ve symptomes in schizophrenia?

302-First-line treatment for a patient in a manic state ?

303-bipolar depression, first-line?

139
304-Which of the following mood stabilizers would be most appropriate in a patient with
liver disease?
(A) lithium
(B) valproic acid
(C) carbamazepine
(D) none of the above

305-Which of the following medications would be considered first-line monotherapy for

an acute episode of mania?
(A) gabapentin
(B) lithium
(C) lamotrigine
(D) haloperidol

306- B blockers has partial agonist? (pindolol)

307-Something about law of thalidomide

308-Side effect of hydroxychloroquine need monitoring? (eye vision)

309- gout + hypertension, which best choice of anti HTN ?

310- Calcium correction ?

311- Patient has renal impairment and has mitral heart or something like that. Which
anticoagulant to choose (warfarin INR (2-3) dabigatran, abixipan, rivaroxiban)

312- A pregnant woman has open angle glucoma. Which treatment to choose?

313- Calculation question: dose 500 mg with two AUC (one oral other one IV). Asked to
calculate the absolute bio availability ?

314- What the effect will be if you give a patient amitryptiline with enteric coated
aspirin?

315-What the effect of alkaling buffer on Aspirin?

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316- The interaction between ibuprofen and aspirin ?

317- Which electrolyte disturbances can predisposed of digoxin toxicity?

318-A surgeon wants to create a guideline of anticoagulant medication to his colorectal

patient and asks you which sources he can look at it?

319-Patient has AF, HTN, Dislipidaemia, other heart problem. His medications captopril,
atorvastatin, clopidogrel, aspirin and other medication. The question is for how long the
aspirin should be used (3 months, 6 months, 12 months or indefinite)

320- A girl newly hired in a pharmaceutical company, the company asked her to do
advertisement to its product that available in two strengths OTC and prescription. Asked
about the legal action they have?

321- A patient has x disease and use x drug. She came to the pharmacy and asked if she
can use a herbal remedy as an alternative to her medication. What should the pharmacist
respond? The options were silly. Non of them recommend her to continue on her
medication and herbal is not an alternative to medication

322- Patient has seizure and depression, which antidepressant should be avoided?

323- A child using phenytoin but not controlled his seizure well, the dr increase the
phenytoin dose. Which of the following is correct (to reduce the seizure by 50%, to
reduce by 25%, to achieve zero seizure, ........)

324-Patient has gastrointestinal spasm what is the management? (Just can remember ergot
of the options)

325- Patient has angina symptoms and relived by nitroglycerin. What type of angina no st
elevation but found something on ECG ? ( angina screpose or something like that,
NSTEMI, STEMI).

326- LONG QUESTION, about women came to hospital and admitted in ICU she on
machinary oxygen supply, her blood pressure is low and I think her potassium is low. And
asked about her condition what she has? Respiratory failure, hypotension and
hypoglycaemia (this what I selected not sure about respiratory failure).

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327- Patient using antibiotics and got diarrhoea (c. Difficile overgrowth). Then asked
which medication has black box label? (Metronidazole, ciprofloxacin, vancomycin, ......)

328-Which medication used with exercise induced asthma ? (Tiotropium, salmeterol,

cortison, Cromolyn sodium)

329-Biological medication store at which temperature?

330- GMP for what?

331-What does biosimilar mean?

332- Cl, gave me plasma concentration and vd.

333- Ca correct, ca = 1.6, albumin =18 and said assuming the normal range of albumin is
45 or 48 couldn’t remember which exactly?

334-Molecules carry fatty acid

335-Something about PUFA and vitamins

336-Aspirin and the role of acetyl group

337-A dr prescribed a drug x 75 mg per kg twice a day, the pharmacist diluted the drug to
be 500mg /10 ml, then diluted with 0.9% nacl to be 5mg/1ml. And asked what will be the
final volume?

338-Which the medication to be conducted or used in laminar flow hood.

339-Side effects of duxorocine related to the dose?

340-Which agency responsible giving accreditation for hospitals quality and safety i
think.

341- A case of a child who has an immunity disease i think and received Immunoglobulin
vaccine one month ago or one week not sure. and his vaccinations schedule is due, one of
the vaccines is MMR. Also, this kid has egg allergy. The question is what the reason to

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defer the vaccination? I can remember two options (because the IG gonna interact with
the vaccination, or because the child has egg allergy)

342-Case of patient has hypotension, tachycardia and I think he is dehydrated. The dr

decided to give him TPN but they found difficult in inserting injection line to deliver the
treatment and TPN. He asked if it’s possible to choose the same line to deliver TPN ?

343-Patient has pain and fibromyalgia which best medication to give? (ibuprofen, local
anaesthesia, muscle relaxant or neuro something inhibitors)

344- What should be avoided while using metronidazole? ( alcohol, smoking, etc...)

345-The question from yazeed file about giving the action of 3 drugs A,B & C and you
have to figure which medication they are (morphin, naloxone, methadone or pentazocine)
the missing information here is the third drug action. So it said the drug C can cause
withdrawal symptoms but it’s not related to the dose.

346- Question of w / w calculation, 10 g of a drug A added to 100g of something.

347- Calculation each ml contains 1250U : patient has to receive 2500 U loading dose
then infusion of 400 U/h for 2 hours 300U/h for 2 hours then 200 U/h for 5 days calculate
the volume that should be dispensed to the patient

348- A truck driver needs antihistamine which medication to give?

349-Acidic drug where best absorption gonna get. (Ph 1-3, ph 4-6, ph6-7 or ph above 7
illinum)

350- Which of the following is a part of the pharmacy and therapeutic committee or drug
therapeutic team ? ( nurse, social work, ......)

351-Who is responsible for an investigator ? (One of the option personal investigator)

352-What is the equivalent dose between (a strength of hydroprednisolon ) and

prednisone or prednisolone ?

353-What is the plasma concentration of IV drug if given as oral assuming the

bioavailability is 65%. Giving you just the dose of IV and bioavailability?
143
Prealbumin ?

✅Carry thyroid
—-
Colipase function ?

✅Co enzyme for lipase

—-

✅
-Encapsulated bacteria?

✅
Hemophilas influence

✅
Klebsiella

✅
Streptococcus pneumoni
Nissirea miningitid
—-
-Mycobatruim test type
Molecular tests for TB

✅nucleic acid amplification test (NAAT

—-

✅
C diff what is it ?
Clostridium difficile
———

-Lub dub the sound of what ?

The first “lub-dub” is the sound of the mitral and tricuspid valves closing.
The second “lub-dub” is the sound of the aortic and pulmonary valves closing soon after.
——-

-Warfarin and aspirin interaction?

✅major haemorrhage.
———-
-Domperidone max duration ?

✅one week.
——-
-Dectermethotphane dose for 10 years old ?
144
✅30 bid
✅Zonisamide /Topiramate
——
-Anti epileptic cause metabolic acidosis ?

-Anti epileptic needs renal dose adjustment ✅Topiramate

——-

✅
-Copd + tachycardia ?
TIOTOPIUM
——-
Malignant hypertension treatment?

✅Sodium notropruside
———-

-‫ ايش الفاكسين اللي تاخذها الحامل ف‬second trimester ?

Tdap ✅
——

-‫ تحسبي‬crcl ‫ بس في تحويل من‬mmol ‫اعرفوه‬

——
-HPV trade name (gardasil)
——
-Case warfarin and with drug increase inr ?

✅metronidazole
———

-Pregnant with UTI

A.Bactrim,
B.cipro ,
145
 ✅
C.meropenam,
B.cefourxime

——-
- multiple sclerosis ttt

✅natalizomab
______________________________________________________________________
patient with heatstroke with cardiac abnormalities they gave him Calcium
his labs results
low Na
Low Ph
high K
the doctor said to the nurse do not open other line ?

so what we should gave him for the hypoPhosphatemia?

potassium phosphate and open new line

potassium phosphate in same line

sodium phosphate and open new line ✅

Sodium phosphate in same line
_____________________________________________________________________
pregnant patient with levothyroxin?

✅
1)should double dose
2) should see ths TSH then adjust the dose
____________________________________________________________________
patient come with difficult to swallow and overall symptoms of goiter (but they didn’t
mention goiter specifically) ‫تستنبط من االعراض‬
the TSH low or high i can’t remember ?

1) iodine deficiency
2) i can’t remember the other choices
______________________________________________________________
78-Which one of the following question's types is used to identify a certain
piece of information?
A. Leading questions
146
B. Open ended questions
C. Closed ended questions
D. D. Process and outcome questions
______________________________________________________________________

✅
Hashimoto's disease what will cause?
1)bradycardia
2)tachycardia
3)weight loss
______________________________________________________________________
heart failure and AFib or other type of arrhythmia use BB other medications what should
not be use?

✅
1) sotalol
2) amidarone
3) other antiArrythmic
________________________________________________________________________
hear failure with symptoms of fluid retention (they didn’t mentioned that you should to
know what are these symptoms) what we should to do?
he take BB, ACEI, furosemide 40mg bid ?

✅
1)add digoxin
2) spironolactone
3) increase furosemide to 80mg bid
________________________________________________________________________
heart failure with symptoms of fluid retention ? they mentioned all hid current
medications one of them furosemide 10 mg?

1) the dose of the current regimen not optimal ✅

2) other choices i can’t remember
_____________________________________________________________________
Pharmacophore ?
‫لها اكثر من تعريف‬
1-group of atoms in a drug molecule that cause biologic and pharmacologic interaction
2- abstract description of molecular features that are necessary for molecular recognition
of a ligand by a biological macromolecule

147