294 Washington Street, 11th Floor

Boston, MA 02108

Dear Candidate,

I am excited and grateful that you are considering joining us on this vital, unique, and rewarding
journey.

While venture funds invest their capital in search of the best financial return, in your job search you
will be determining where to invest your time to achieve the highest overall return. In doing so, you’ll
likely seek to build your legacy, have fun while working, and create generational wealth. When
interviewing here and elsewhere, I encourage you to gather key data, ask the really hard questions,
and choose wisely.

While we are only interested in missionaries joining us on this journey, we want you to be highly
incentivized and properly rewarded for your contributions in furtherance of our mission. As such, we
will share everything with you as if you were a venture capitalist conducting your due diligence.

Consistent with our unwavering cultural commitment to transparency and clarity, this document is
designed to help you understand who we are, why we’re here, what we stand for, why it matters,
how we will become successful, and what it could mean if we are able to achieve our mission.

Consistent with our commitment to craft, it’s essential you take the time to read this so that we are
all set up for success throughout the interview process.

I hope to meet you along the way!

Patrick
 294 Washington Street, 11th Floor
Boston, MA 02108

Disclaimer

Please keep in mind that the information contained herein is confidential and includes forward-
looking projections, which are necessarily based upon estimates and assumptions that are inherently
subject to significant business, economic, regulatory, and competitive uncertainties and
contingencies, many of which are beyond the control of TetraScience, Inc. (the “Company”) and its
management, and are based upon assumptions with respect to future business decisions, which are
subject to change. These projections and actual results will vary, and those variations may be
material. Neither the Company nor any employee or member of management of the Company makes
any representation or warranty, expressed or implied, as to (i) the accuracy or completeness of the
information included herein or (ii) that the forward-looking statements and projections set forth
herein (or in any other materials delivered to you) or any of the contemplated results of such
forward-looking statements or projections will be achieved. You agree not to copy, reproduce, or
distribute this document to anyone else, and you will either destroy or return this document at the
request of the Company.

Nothing herein constitutes tax, accounting, financial, investment, regulatory, legal, or other advice,
and you are advised to consult with your tax, accounting, financial, investment, regulatory or legal
advisers. The information presented in these materials has been developed internally and/or
obtained from sources believed to be reliable; however, the Company does not guarantee or give any
warranty as to the accuracy, adequacy, timeliness, or completeness of such information, and assume
no responsibility for independent verification of such information.

THIS DOCUMENT IS PROVIDED FOR INFORMATIONAL PURPOSES ONLY AND IS NEITHER AN OFFER
TO SELL NOR A SOLICITATION OF AN OFFER TO PURCHASE SECURITIES. SUCH AN OFFER, IF ANY,
WILL ONLY BE MADE PURSUANT TO DEFINITIVE DOCUMENTATION THAT WILL BE DISTRIBUTED AT
A LATER DATE.
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Boston, MA 02108

Our Vision

Solving humanity’s grand challenges by accelerating and improving scientific outcomes.

Mission

To combine deep domain knowledge, the industry’s only purpose-built R&D data cloud, and the
largest network of life sciences innovators, to harness the power of the world’s scientific data to
enhance and extend human life.

Our Company

TetraScience was originally founded by researchers from Harvard and MIT to prepare the world’s
R&D labs for the exigent demands of the 21st century, with an initial product focus on IoT. These
research labs, in vital industries such as life sciences, chemicals, agricultural, materials, and energy,
are upstream to the transformational innovations required to solve humanity’s greatest challenges.

Based upon extensive public data, we estimate that these labs currently spend more than $300B
annually on research and development, and this is expected to exceed $500B by 2026. Despite their
critical importance to humanity, these labs remain dependent upon 20th century software and data
stacks, resulting in scientific data silos, limited collaboration, and suboptimized discovery.

TetraScience is leading the replatforming of the world’s research labs by migrating their experimental
data to the Tetra R&D Data Cloud, enabling new classes of applications, and positioning the data for
advanced analytics and AI-based discovery. TetraScience is operating in a greenfield market, has no
pure play competitor, and is positioned to dominate the R&D data cloud market much as Veeva
(VEEV: $30B) and Medidata (acquired: $5.7B) have in commercial and clinical trial clouds, respectively.

In May 2019, B2B cloud pioneer and early Unicorn founder, Patrick Grady, joined TetraScience as
Executive Chairman to partner with original founder, Siping “Spin” Wang, to help the company
capitalize on early customer learnings, deemphasize its IoT product, and chart a new course to
becoming the dominant R&D Data Cloud company. Our Tetra 2.0 origin story is captured in a blog
post authored by Patrick https://bit.ly/3qFMmE5 in connection with our Series B funding.
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Boston, MA 02108

Product-market fit for the Tetra R&D Data Cloud was quickly established and growth metrics have
been best-in-class with 2020 ARR growing 10x over 2019, and 2021 ARR increasing 3x over 2020.
We plan to double ARR again in 2022 and 2023, respectively.

Our obsession with clarity and execution has also led to stellar capital efficiency. The company raised
an $11M Series A in 2020 and had $9M left on its balance sheet prior to closing an $80M Series B
funding, co-led by Insight Partners and Alkeon Capital, on March 26, 2021. The company entered
2022 with nearly all of its Series B proceeds on the balance sheet.

In February 2021, Patrick became CEO of the company and Spin took on the President and CTO roles.

Experimental Data: From Second to First Class Status

Experimental data – possibly the world’s most important data – has been treated as a second class
asset.

The world’s labs have limited access to their R&D data, which is typically trapped in disparate data
silos. These labs have to rely upon tedious and error-prone manual transcription or rigid, fragile, and
costly point-to-point integrations to move the data into their R&D workflows. Moreover, they’re
unable to analyze their data or apply advanced data science in a vendor-agnostic and holistic manner
using best-of-breed data analytics applications. Critically, in the absence of large, normalized, and
organized data sets, there’s no plausible possibility of applying AI/ML in any meaningful manner.

When R&D organizations attempt to implement their own data platforms using horizontal tools such
as MuleSoft, Pentaho, or Boomi, they have to build connectors and integrations themselves.
Typically, these integrations are outsourced to consulting companies and these professional service
projects require a significant amount of time and investment to build and maintain. Worse, these
integrations are sometimes outsourced as custom development to one of the point providers
themselves – e.g., instrument manufacturers, ELNs, LIMS vendors, etc. – resulting in highly vendor-
specific and rigid point-to-point integrations that become obsolete with invariable changes in the lab
environment.
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Boston, MA 02108

The Tetra R&D Data Cloud

The Tetra R&D Data Cloud represents a fundamental shift in global R&D by treating experimental
research and development data as a first-class business and product priority.

As opposed to internal IT teams and/or systems integrators, TetraScience treats data integrations as
productized, reusable, and extensible offerings with well-defined APIs which allows for easy
configuration and consumption. This stands in vivid contrast to the traditional project-based
methodology and point-to-point architecture of IT teams and systems integrators due to their
environments, objectives, and business models.

With the addition of each new customer, the Tetra R&D Data Cloud adds to its growing library of
productized and maintainable integrations, thus all customers benefit from the collective innovation
produced by the industry. Additionally, the costs of creating and maintaining integration connectivity
are shared by the entire network, and the expansion of the network in turn benefits every participant,
creating a network effect. The Tetra R&D Data Cloud helps these labs accelerate innovation and
future-proof their environments.

In addition to its best-in-class cloud architecture and network-based model, TetraScience has built
up deep domain expertise. Understanding the nature, importance, and relationships of various
experimental data types, and creating well-defined taxonomies and contextual and actionable
ontologies, gives TetraScience material competitive advantages over horizontal data companies.

The Tetra R&D Data Cloud combines the Tetra Data Platform and the Tetra Partner Network.

The Tetra Data Platform is the R&D industry’s only enterprise-grade data integration and data
engineering platform, specifically designed to provide research labs the flexibility, scalability, and
data-centric capabilities to enable easy access to centralized, standardized, and actionable scientific
data.
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Boston, MA 02108

The Tetra Partner Network represents the world’s largest ecosystem of lab instruments, informatics
applications, CRO/CDMOs, and analytics and data science partners, creating seamless interoperability
and an innovation feedback loop that we believe will drive the future of R&D.

TetraScience’s open and data-centric approach to re-platforming experimental data in the cloud
positions it to be a dominant player in the inevitable AI-enabled drug discovery market. Ultimately,
properly engineered experimental data, fueled by cloud computing and AI, will allow TetraScience to
fulfill its mission. While TetraScience has commenced its journey by helping pharmas replatform their
$177B in annual R&D investments to the cloud, it will move into additional R&D verticals such as
chemicals, agricultural, materials, and energy, which possess similar markers.

Data Engineering Platform

• Vendor-agnostic, data-centric platform covering the full life cycle of data acquisition,
harmonization, AI/ML/enrichment, and collaboration.

• Accelerates innovation by unifying siloed R&D data, with state-of-the-art data exploration
and data science capabilities.

• Leverages cloud infrastructure natively, giving enterprises unprecedented elasticity for

storage and processing without IT overhead.

Network

• The largest network of instruments, informatics applications, CRO/CDMOs, analytics and data
science software partners, driving a feedback loop of innovation.

• Open philosophy future-proofs Data Cloud investment, as enterprises evolve and enhance
their R&D ecosystem.

Data Science

• Our team combines a deep understanding of Life sciences R&D with cloud-native mindsets
and data science expertise.
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• Native platform support for leading data science tools and custom configurations.

• Supercharged by our library of templates, models, pre-built pipelines and more, driven by the
leading global pharmaceutical and Biotech companies.

Data Applications

• Rapidly prototype, build, test, deploy and scale custom data applications.

• Benefit from a growing number of bundled apps created by TetraScience and network
partners.

Investment Profile

TetraScience resides at the nexus of two of the most important venture capital investment themes –
the movement of the world’s data to the cloud, and the application of cloud computing and artificial
intelligence to life sciences and other complex experimental data challenges.

TetraScience is to Snowflake, what Veeva was to Salesforce - the highly focused vertical domain
expert, against the backdrop of a horizonal and distracted Gorilla. Like Veeva, TetraScience will
dominate in life sciences and then move into adjacent verticals which possess many of the same lab
markers.

Greenfield market, no competition, and deep and wide moats

TetraScience is the world’s only pure play R&D Data Cloud company, operating unimpeded and
without a direct scaled competitor, and is building wide and deep competitive moats which will make
it exceedingly difficult for new entrants to compete. We have yet to see a legitimate competitor in any
of our enterprise pharma deals and paid POCs due to a combination of first-mover advantage, best-
in-class cloud capabilities, an open platform and agnostic network, and deep domain data
expertise.
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Boston, MA 02108

Our competition is comprised of internal IT and/or systems integrators/body shops, end-point

vendors who dabble in integration but are focused elsewhere and lack the brand and market
permission to be open and agnostic, and subscale software vendors who masquerade as cloud
companies but are in reality glorified body shops working on point-to-point integrations with no
understanding of advanced data engineering.

We believe this market has been overlooked, underfunded, and underdeveloped by venture-backed
startups due to a misguided view that R&D lab data represents a niche market and that these
advanced labs, which have historically been technology laggards, wouldn’t move their data to the
cloud. As such, venture capitalists have instead focused on pure-play software-enabled Biotech
companies and end-point cloud lab applications (e.g., ELNs > Benchling.)

In reality, experimental R&D labs represent a large, growing, and underserved market, and one which
requires deep domain expertise to establish credibility with buyers and influencers. When large
pharmas have replatformed – as they have in commercial activities and clinical trials – it’s yielded
Category Kings such as Veeva and Medidata, with a combined value of >$35B.

Notably, Covid-19 has heightened the urgency to replatform to the cloud as pharmaceutical
companies face enormous societal and governmental pressure to radically accelerate discovery.
TetraScience is a major beneficiary of this otherwise unfortunate exogenous event.

Product, market, and business model vectors yield large and logical expansion opportunities

TetraScience’s product strategy, market focus, and business model – i.e., open data platform, life
sciences, and 3rd party partner network – combine to serve as a strong and leverageable foundation
from which to seamlessly expand into logical adjacencies, resulting in accelerating revenue, higher
switching costs, and increasing returns to scale.
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Boston, MA 02108

We define this internally as the SEVENS strategy – i.e., stack evolution (SE), vertical expansion (VE),
and network scale (NS):

• Our open and native cloud data platform is designed to assemble the largest and most
organized experimental data sets in the world. We believe this gives us unparalleled
advantages in enabling advanced data-enabled apps, as well as native and 3rd party AI/ML
capabilities, which we envision as the core building blocks for future R&D discovery.

• Our beachhead in life sciences - the most dominant and demanding R&D lab segment -
allows us to move into other large R&D lab verticals with common markers including
chemicals, agricultural, materials, and energy, and more, with greater leverage and velocity
than potential new entrants.

• Our partner network represents the largest ecosystem of R&D innovators. We expect these
partners to leverage our productized integrations and advanced data engineering capabilities
to build configurable data apps on our platform and enter into commercial go-to-market
agreements with us.

• These activities will accelerate bookings and engender a sense of category and company
inevitability across the ecosystem with a constant stream of press releases, references, and
3rd party validation. This will also yield considerable platform cross-sell opportunities as we
execute a land-and-expand GTM model following sale of these Tetra-enabled apps.

Category Economics

Category Kings dominate in the winner-take-all world of tech economics in which they capture
virtually all of a market's mindshare, market share, revenue, profit, and market capitalization. Indeed,
the enterprise valuation of the Category King is invariably larger than all other vendors/competitors
combined, and extensive supporting research exists in this regard.
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Boston, MA 02108

A recommended book covering the creation and importance of Category Kings is “Play Bigger” which
was written by some of Patrick’s friends - https://amzn.to/2ThJUE7

Patrick has a history of creating categories and authored a blog post covering our opportunity to
become the dominant R&D Data Cloud category leader - https://bit.ly/39EdFab

TetraScience’s public vertical life sciences comp is Veeva (VEEV), while Snowflake (SNOW) is our best
cloud data comp. Our private market comp is Benchling, which closed a 2021 growth round at a
$6.2B valuation, representing ~60x 2021 ARR. Benchling wants to be the one-stop cloud shop for
Biotech R&D, and we estimate that they’re currently doubling bookings YoY.

We do not compete with Benchling, but they are our best private valuation proxy. Benchling wants
to bring the world’s R&D labs to the cloud like we do, but they have executed an outside-in data
strategy, giving scientists modern tools and UXs to simplify their workflows. They’ve built an
electronic lab notebook (ELN) and have numerous competitors in their initial ELN market. Benchling’s
vision is to build an end-to-end stack for labs - a vertical walled garden. While this currently works
well within the smaller Biotech segment given their simple IT environments, it’s a non-starter for lab-
wide data in large Pharmas and larger Biotechs. Customers are clear -- they won’t trust any end-
point provider with all of their data, and they demand an open data cloud such as TetraScience.

Notably, Alkeon led Benchling’s 2020 growth round and co-led our 2021 Series B funding.

Large enterprise Pharmas and larger Biotechs (like all global R&D labs) have heterogeneous IT
environments, longstanding and entrenched vendor relationships, and high process and distributed
R&D complexity. Global R&D labs are actively seeking an open platform which allows them to
connect their existing ecosystem of providers and data sources in the cloud. They also want to
future-proof their business by seamlessly plugging and playing new best-in-breed vendors when
appropriate, while avoiding vendor lock-in.
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Our Values and Culture

In the spirit of transparency and clarity, corporate values are all-too-often “words on a wall” and/or
they’re viewed as a necessary evil by management, and/or they’re little more than vacuous virtue-
signaling efforts designed to placate employees and other stakeholders.

The vast majority of startups are also black-boxes of data, with management naively believing that
top-down mandates, a few corporate metrics, some employee perks, and all-hands cheerleading
sessions, are sufficient to motivate employees and accomplish company goals and missions.

We believe these approaches are deeply flawed and sub-optimize outcomes for all stakeholders.

I owe it to every candidate to be clear on this front -- you cannot possibly be successful here
unless you're committed to the values set forth below. This is who we are and what we stand for
and it's my responsibility to set you up for success by setting appropriate expectations of all of us -
me included. If I ever let you down by not living up to these values, it's incumbent upon you to let me
know.

Our core values are designed to guide our behaviors, actions, and decisions such that we operate as
one - decisively, productively, and collaboratively - without requiring management’s permission. We
are seeking true missionaries on this journey. We are seeking problem-solvers and doers who run
toward challenges. We are seeking those that possess the intellectual horsepower, curiosity,
humility, and empathy to fulfill our mission for humanity’s sake.

Transparency and Context

Our vision is global in scope and our mission will impact all of humanity over time. To execute on
these ambitious challenges, we must fully harness and maximize all of our assets – internal talent,
customer input, partner collaboration, and investor capital.

We believe this starts with radical data transparency and business context, and that by openly and
proactively sharing all vital data and making it actionable, our employees and stakeholders can solve
any problem presented to them.
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Boston, MA 02108

Asking our employees to execute in the absence of data and business context is unfair and irrational.
We trust our people will make the right decisions and overcome any challenges when given data and
context.

Trust and Collaboration

All too often, companies are functionally-siloed due to a lack of trust and collaboration between and
among management, functional leaders, and employees, and they cultivate toxic cultures defined by
internal politics and highly-subjective, personality-driven outcomes.

We believe there can only be trust when there is transparency. While data transparency is core to our
values, so is transparency in our communications so that we can build a company on a foundation of
trust.

We are committed to always communicating openly and honestly at every level of the organization,
functionally, cross-functionally, internally, and externally. We are committed to empowering our
employees to drive positive change across our entire ecosystem.

We expect all employees, including executives and managers, to be open and receptive to
constructive feedback, while not avoiding difficult conversations. Equivocation, wishy-washy
performance reviews, and conflict-avoidance help no one and ultimately set people, the company,
and our stakeholders up for failure. We expect honesty, transparency, and kindness in all our
communications.

We value and rely upon critical thinking and individual ideas, but we operate as one and collaborate
cross-functionally, aligned by our goals in the pursuit of our vision and mission. There is simply no
path to success for us in the absence of trust and collaboration among all of our stakeholders.

Fearlessness and Resilience

What we are endeavoring to do is important and difficult. If it were easy, some other company would
have done it already, and countless people around the world would have demonstrably improved
lives.
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We are committed to a culture defined by trust and collaboration and fueled by data transparency
and business context. While we view these as necessary conditions for success, we know they are
insufficient. To fulfill our potential, we must be fearless and resilient. We proactively run toward
challenges of all types, we unblinkingly acknowledge and confront the brutal facts - which all
innovative growth companies invariably face – and we embrace uncertainty and take calculated risks.

When we fail, individually or collectively, we quickly determine - with data - why we failed, we pick
ourselves and our teammates back up, and we recommit to our mission, better prepared than before.

Equality of Opportunity

Our mission is underscored by a profound commitment to aiding humanity on a global scale. We

cannot imagine our journey without a workforce which reflects humanity’s diversity.

We seek out the best of the best, regardless of gender, ethnicity, race, or age; we seek out those who
embody our common values but bring with them unique and invaluable perspectives, talents, and
advantages.

We are committed to ensuring that all employees feel welcomed, respected, and deeply valued. To
ensure that we are walking this walk, we are committed to equal opportunity and equal
compensation in all that we do. We cannot underscore enough our commitment to this ideal.

We do not virtue-signal; instead, we walk the walk of equality of opportunity in all we do.

Alignment with Customers and Partners

We seek to create abundance in all we do and avoid zero-sum outcomes.

While there is much to be proud of when working in a startup, all too often companies like ours
become arrogant and dismissive of the needs and inputs of their customers and partners. They’re
convinced of their own brilliance, and they mistake venture-backing, innovation, and disruption, for
actual commercial success and even the moral high ground.
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We know that our customers and partners are the key to unlocking the world’s most important
innovations. We know that their success is our success, we are honored and humbled by their
commitment to us, and we are completely committed to ensuring they achieve their missions.

We don’t believe we know more than customers and partners. We understand that they face
numerous internal and market-based challenges yet have unique assets to bring to bear in solving
the world’s most important problems. We also understand that we have unique assets and insights
to bring to bear but can’t achieve our mission without them.

We live and breathe this dedication to our customers and partners, and we treat them with respect
and humility and not frustration or disdain, while also passionately and collaboratively showing our
customers and partners what’s possible to achieve with our products.

In turn, our customers drive us to constantly invent different ways to surprise and delight them and
provide us with feedback that propels us to constantly improve.

Commitment to Craft

We are passionate missionaries, but the importance of our mission necessitates that we take our
craft seriously and seek to be best-in-class in all we do, regardless of our functional role, seniority, or
tenure.

We are always prepared and highly organized. We sweat the details, as the small things enable the
big things. We are professional in all we do. We communicate clearly and with purpose. We are
proactive and we follow through. We collaborate cross-functionally and cross-enterprise. We close
gaps. We assume nothing and verify everything. We have high expectations of ourselves and those
around us. We understand that we are members of a team and not a collection of individuals and we
seek to maximize outcomes for all involved.

We combine intellectual horsepower, intellectual curiosity, humility, and empathy to ensure we are
always learning and evolving.