Riboflavin Deficiency

Riboflavin deficiency is extremely rare in the United

States. In addition to inadequate intake, causes of
riboflavin deficiency can include endocrine
abnormalities (such as thyroid hormone insufficiency)
and some diseases [1]. The signs and symptoms of
riboflavin deficiency (also known as ariboflavinosis)
include skin disorders, hyperemia (excess blood) and
edema of the mouth and throat, angular stomatitis
(lesions at the corners of the mouth), cheilosis (swollen,
cracked lips), hair loss, reproductive problems, sore
throat, itchy and red eyes, and degeneration of the liver
and nervous system [1-3,8]. People with riboflavin
deficiency typically have deficiencies of other nutrients,
so some of these signs and symptoms might reflect
these other deficiencies. Severe riboflavin deficiency
can impair the metabolism of other nutrients, especially
other B vitamins, through diminished levels of flavin
coenzymes [3]. Anemia and cataracts can develop if
riboflavin deficiency is severe and prolonged [1].