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Chapter 07
Depressants and Inhalants
1. (p. 147) The CNS depressants include various prescription drugs referred to as
A. GHBs.
B. sedative-hypnotics.
C. entheogens.
D. catecholamines.
2. (p. 148) Which of these is NOT one of the early sedative-hypnotics used in medicine?
A. chloral hydrate
B. paraldehyde
C. butyrate
D. bromide salts
3. (p. 148) What has kept paraldehyde from being widely used?
A. danger to the CNS
B. bad taste and odor
C. danger to the respiratory system
D. irritation to the gastric system
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Chapter 07 - Depressants and Inhalants
5. (p. 149) Among the barbiturates, when prescribing a sleeping pill (hypnotic), physicians
would usually choose a
A. higher dose of a short-acting drug.
B. lower dose of a long-acting drug.
C. higher dose of a long-acting drug.
D. lower dose of a short-acting drug.
6. (p. 150) Two drugs that were introduced as being safer than the barbiturates, but in the long
run proved to be not much safer, were
A. fluoxetine and paroxetine.
B. toluene and xylene.
C. meprobamate and methaqualone.
D. perphenazine and thiazine.
7. (p. 152) The major advantage of the benzodiazepines over the barbiturates seems to be the
A. lower cost.
B. greater effectiveness.
C. shorter duration of activity.
D. greater safety margin.
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Chapter 07 - Depressants and Inhalants
8. (p. 152) Librium (chlordiazepoxide) and Valium (diazepam) were the first widely sold
A. benzodiazepines.
B. barbiturates.
C. methaqualones.
D. sedatives.
10. (p. 153) When benzodiazepines bind to their receptor site, they
A. release barbiturates.
B. block acetylcholine receptors.
C. reduce the membrane electrical potential.
D. enhance the inhibitory effects of GABA.
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Chapter 07 - Depressants and Inhalants
12. (p. 153) The four most widely sold benzodiazepines are all longer-acting drugs sold
primarily as
A. anxiolytics.
B. analgesics.
C. hypnotics.
D. antidepressants.
13. (p. 153) Sedative-hypnotic agents bind to which receptors in the brain?
A. glutamate
B. GHB
C. serotonin
D. GABA
14. (p. 158) Animal self-administration experiments and studies of drug choice among humans
indicate that
A. benzodiazepines have no dependence liability.
B. rats and people are very different in the drugs they choose to self-administer.
C. short-acting barbiturates are more likely to lead to dependence than any of the
benzodiazepines.
D. all of the benzodiazepines have high dependence liability.
15. (p. 158) Withdrawal from long-term use of sedative-hypnotic drugs is characterized by
A. aching, high blood pressure, drowsiness.
B. anxiety, impaired concentration, insomnia, convulsions.
C. rapid mood swings.
D. minor discomfort, but no serious symptoms.
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Chapter 07 - Depressants and Inhalants
16. (p. 163) One of the most dangerous acute effects of taking depressants in combination with
alcohol is
A. the "cheese reaction".
B. respiratory depression.
C. seizures.
D. slurred speech.
17. (p. 158) Which of the following drugs could theoretically be used to treat barbiturate
withdrawal?
A. methamphetamine
B. fluoxetine
C. alcohol
D. modafinil
18. (p. 160) One of the oldest gaseous anesthetics, popularly known as "laughing gas," is
A. butane.
B. diazepam.
C. pentobarbital.
D. nitrous oxide.
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Chapter 07 - Depressants and Inhalants
20. (p. 161) The modern era of abuse of volatile solvents by young people can be traced to a
1959 newspaper report of
A. gasoline huffing.
B. glue sniffing.
C. lead paint poisoning.
D. nitrite abuse.
21. (p. 162) Inhalant use has traditionally been more common among
A. poor Hispanic and Native American youth.
B. middle-class white children.
C. middle-class black children.
D. construction workers.
23. (p. 162) The usual recreational dose of GHB when taken alone is about
A. 10-20 milligrams.
B. 100 micrograms.
C. 1-5 grams.
D. 100-200 grams.
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Chapter 07 - Depressants and Inhalants
24. (p. 161) Anecdotally, __________ (or "poppers") are used to enhance sexual pleasure.
A. nitrous oxide
B. amyl nitrite
C. GHB
D. Rohypnol
25. (p. 148) Paraldehyde is a CNS depressant that is currently available in several over-the-
counter medications.
FALSE
26. (p. 149) When barbiturates were the most popular sedative-hypnotics, low doses of the long-
acting types were used as sleeping pills.
FALSE
27. (p. 151-152) Benzodiazepines replaced barbiturates primarily because they were believed to be
safer.
TRUE
28. (p. 152-153) Ambien (zolpidem) is a popular benzodiazepine used to treat anxiety.
FALSE
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Chapter 07 - Depressants and Inhalants
29. (p. 151) Sodium pentathol is long-acting barbiturate used to treat insomnia.
FALSE
30. (p. 158) Among the sedative-hypnotic drugs, short-acting barbiturates seem to be the most
likely to lead to drug dependence.
TRUE
31. (p. 160) Nitrous oxide ("laughing gas") is a Schedule I controlled substance.
FALSE
32. (p. 162) The majority of "huffers" (users of inhalants) are above age 25.
FALSE
33. (p. 160) Volatile solvents that act as CNS depressants are found in a wide variety of
household products.
TRUE
34. (p. 156) According to the DAWN data set, zolpidem-related emergency room visits declined
between 2005 and 2010.
FALSE
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McGraw-Hill Education.
Chapter 07 - Depressants and Inhalants
Essay Questions
35. (p. 158) Explain how a drug's rate of onset and duration of action affect psychological
dependence and withdrawal. Give examples from this chapter.
Drugs with rapid onset of action will be more likely than slow-acting drugs to produce
psychological dependence. Examples include short-acting barbiturates, like secobarbital, and
Xanax, a rapid-acting benzodiazepine. Physical dependence occurs when the drug leaves the
system more rapidly than the body can adapt. Drugs with a short duration of action, such as
secobarbital, leave the body rapidly and are much more likely to produce physical withdrawal
symptoms than are longer-acting drugs.
36. (p. 156) Discuss the use of medications as hypnotics (sleeping pills). What types of drugs are
used, and what are some of the concerns associated with the use of sleeping pills? Are there
any alternatives to drug use?
Although many people complain of poor sleep, most do not take prescription medications for
this. Both benzodiazepine (e.g., Halcion) and non-benzodiazepine (e.g., Ambien) drugs are
typically used. Concerns include dependence, respiratory depression when combined with
alcohol, and people driving, walking around, etc., while still under the drug's influence
("sleepwalking").
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Test Bank for Drugs, Society, and Human Behavior 16th Edition
37. (p. 162-163) GHB has been used for several purposes. Describe its recent history of various
medical and recreational uses and its status as a controlled substance.
GHB was sold as a dietary supplement and used to stimulate muscle growth. In high doses,
GHB has alcohol-like effects, and its recreational use led to banning it from dietary
supplements in 1990. Its use as a date-rape drug led Congress to direct that GHB be placed on
Schedule I in 2000. In 2002, a prescription version (Xyrem) was made available for treating
narcolepsy. Xyrem is on Schedule III.
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