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Human Nutrition
Human Nutrition
A
● ll living organisms require food.
● Plants produce their food through photosynthesis, while animals must obtain it by consuming plants or other
animals.
● Food serves several crucial functions in plants and animals:
○ Supports growth by providing the necessary substances for creating new cells and tissues.
○ Acts as a source of energy, essential for various biological processes, such as respiration, building
large molecules, and powering animal activities.
○ Facilitates the replacement of worn and damaged tissues, like red blood cells, skin, and wound repair.
alanced Diets:
B
A
● balanced diet contains all the essential nutrients in the right proportions for maintaining good health.
● Essential nutrients include carbohydrates, fats, proteins, vitamins, minerals, fiber, and water.
● Carbohydrates and fats supply energy for internal body processes, maintaining body temperature, and
supporting physical activities.
● Energy derived from food is measured in calories or joules.
● The average daily energy intake needed is about 12,000 kJ, but it varies based on factors like age,
occupation, and activity level.
● Females generally require less energy than males, and children need more energy for growth.
● Excess energy from food can be stored as glycogen in the liver or as fat in the body.
lasses of Food:
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● hree main classes of food: carbohydrates, proteins, and fats.
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●Carbohydrates are a primary source of energy, like sugar and starch.
●Fats are found in animal products and plant oils, with the highest energy content.
●Proteins supply amino acids needed for building and repairing tissues.
●Plant-based sources of protein are available, but they may require careful selection to ensure complete
amino acid profiles.
itamins:
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Vitamins are organic compounds needed in small quantities for various biochemical processes.
●
● They do not provide energy directly but are essential for health.
● Vitamins can be water-soluble or fat-soluble.
● Deficiency in specific vitamins can lead to vitamin-deficiency diseases.
Examples of Vitamins:
V
● itamin C is found in citrus fruits and is essential for skin and gum health. Deficiency leads to scurvy.
● Vitamin D is produced by the skin when exposed to sunlight and aids in calcium absorption. Deficiency can
result in rickets.
ineral Ions:
M
● E ssential mineral ions include iron, which is needed for hemoglobin production, and calcium, vital for bone
and muscle function.
● Iron deficiency can cause anemia.
● Calcium deficiency can lead to weak bones and other symptoms.
ietary Fiber:
D
Dietary fiber, also known as roughage, consists of plant cell walls that humans cannot digest.
●
● It helps maintain healthy digestion and prevent constipation.
● Good sources of fiber include vegetables, fruits, and wholemeal bread.
ater:
W
W
● ater is a vital component of the body, constituting around 70% of most tissues.
● It serves as a solvent for various biochemical reactions, aids in digestion, and regulates body temperature.
● The body constantly loses water through evaporation, sweating, urination, and breathing, necessitating
regular water intake.
nergy from Food Experiment:
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● T o measure the energy content of a food item, conduct an experiment where you burn a sample and
calculate the energy released by heating a known quantity of water.
● The energy content can be compared to official values to assess accuracy.
Safety Notes:
Ensure eye protection.
●
● Take care when handling the needle and open flame.
● Proper ventilation and adult supervision are required.
Digestive System:
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● eeding involves the intake, chewing, and swallowing of food.
● However, for food to benefit the body, it must undergo digestion, turning solid food into soluble forms and
reducing molecular size.
● Soluble products are then absorbed into the bloodstream, which delivers nutrients to living cells in tissues
and organs.
egions of the Alimentary Canal and Their Functions:
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● he alimentary canal is a tubular structure in the body where food digestion occurs.
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● Soluble nutrients are absorbed, and indigestible components are expelled.
● The inside of the alimentary canal is lined with layers of cells called an epithelium.
● Epithelial cells are continually replaced as they are worn away during food movement.
● The lining also contains cells that produce mucus, a slimy liquid that lubricates and protects the canal.
● Mucus might prevent digestive enzymes from damaging the canal.
● Some digestive enzymes are produced within the canal's lining, while others originate from glands located
outside the canal. Glands release enzymes into the canal through ducts.
● Examples of digestive glands include salivary glands and the pancreas.
The alimentary canal features numerous blood vessels near its lining, which supply oxygen, remove carbon
●
dioxide, and absorb digested food.
Physical Digestion:
● P hysical digestion involves breaking down food into smaller pieces without altering the chemical structure of
the food molecules.
● Key processes of physical digestion occur in the mouth, stomach, and with the aid of bile.
● The human diet is omnivorous, similar to carnivores in terms of tooth types, but human teeth are not
designed for hunting or crushing bones.
Types of Human Teeth and Their Functions:
● Human teeth have distinct functions:
○ Incisors: Located at the front and used to cut food into smaller pieces.
○ Canines: Pointed and larger, behaving like additional incisors.
○ Premolars and molars: With knobbly surfaces that crush food into smaller pieces, aiding in digestion.
Tooth Structure:
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● eeth have a portion above the gum line, covered by hard enamel.
● The root of the tooth is embedded in the jaw bone, covered by cement.
● Beneath the enamel is a softer layer called dentine, and within the dentine is the pulp cavity containing
nerves and blood vessels.
tomach's Role in Physical Digestion:
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● he stomach stores food and transforms it into a liquid form.
T
● The stomach's elastic walls stretch as food accumulates.
● Muscles in the stomach wall contract and relax, churning and squeezing the food with gastric juice.
● This process increases the food's surface area for more efficient digestion.
● The duration of food retention in the stomach depends on its content, with water passing through quickly,
while meals with protein and fat may stay for longer.
● The stomach has a valve at its base to prevent solid food from passing through and allows liquid products of
digestion to enter the small intestine.
eristalsis:
P
● P
eristalsis is a wave of contractions in the muscular layers of the alimentary canal, pushing food along the
canal.
ile:
B
● B ile is a green, watery fluid produced in the liver, stored in the gallbladder, and delivered to the duodenum
through the bile duct.
● Bile contains bile salts, which emulsify fats, breaking them into small droplets with a larger surface area for
more efficient digestion.
● The green color of bile is due to bile pigments formed from the breakdown of hemoglobin in the liver.
hemical Digestion:
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● C hemical digestion involves breaking down large, insoluble food molecules into small, soluble ones through
the action of enzymes.
● This process allows the small molecules to be absorbed through the alimentary canal's epithelium and into
the bloodstream.
● Enzymes are the chemicals responsible for dissolving food, significantly accelerating the breakdown
compared to a simple immersion in water.
● Starch is digested into glucose, proteins into amino acids, and fats into glycerol and fatty acids.
unctions of the Main Parts of the Alimentary Canal:
F
M
● outh: Ingestion, physical digestion by teeth, andchemical digestion of starch using salivary amylase.
● Salivary Glands: Produce saliva containing amylasefor starch digestion and to lubricate and stick food
particles.
● Esophagus (Gullet): Transfers food from the mouthto the stomach through peristalsis.
● Stomach: Produces gastric juice with protease forprotein digestion and hydrochloric acid to create an
optimal pH for protease and kill bacteria.
● Duodenum (First Part of Small Intestine): Receivespancreatic juice and bile for chemical digestion of
proteins, fats, and starch and emulsification of fats.
● Ileum (Second Part of Small Intestine): Site for absorptionof digested food, water, and final stages of
chemical digestion.
● Pancreas: Secretes pancreatic juice containing enzymesfor digestion of proteins, fats, and starch.
● Liver: Produces bile to emulsify fats, performs assimilationof nutrients like glucose, and converts excess
amino acids into glycogen.
● Gallbladder: Stores bile produced in the liver andreleases it into the duodenum.
● Colon (First Part of Large Intestine): Absorbs waterfrom undigested food and bile salts to return to the
liver.
● Rectum: Stores feces.
● Anus: Involved in egestion of feces.
igestion of Starch:
D
● S tarch digestion occurs in two places: the mouth (by salivary amylase) and the duodenum (by pancreatic
amylase).
● Amylase works best in a neutral or slightly alkaline pH and breaks down large, insoluble starch molecules
into smaller, soluble maltose molecules.
● Maltose, a disaccharide sugar, is further broken down to glucose by the enzyme maltase in the epithelial
cells of the villi.
igestion of Protein:
D
P
● roteins are digested into smaller molecules called peptides and then into completely soluble amino acids.
● Pepsin is a protease secreted in the stomach, functioning optimally in the acidic stomach environment.
● Trypsin, secreted by the pancreas and activated in the duodenum, works on proteins and peptides under
alkaline conditions.
● Epithelial cells of the villi contain enzymes in their cell membranes, such as peptidase, which complete the
breakdown of peptides into amino acids.
unction of Bile in Chemical Digestion:
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● B ile is slightly alkaline, containing sodium hydrogencarbonate, and neutralizes the acidic mixture of food and
gastric juices as it enters the duodenum.
● Bile, along with pancreatic juice, creates alkaline conditions in the duodenum, providing the optimal pH for
enzyme activity.
bsorption:
A
● A
bsorption Locations:Nutrients are primarily absorbedin the ileum (second part of the small intestine),
and water absorption also occurs in the colon (part of the large intestine).
● Efficiency of Ileum for Absorption:The ileum is efficient for nutrient absorption due to several factors:
○ Large surface area provided by its length.
○ Circular folds in its internal surface, each bearing villi, which are tiny projections that may be
finger-like or flattened.
○ Thin lining epithelium, facilitating the rapid passage of fluids.
○ Presence of microvilli on the outer membrane of epithelial cells, significantly increasing their surface
area.
○ A dense network of blood capillaries in each villus.
● Absorption Mechanism:Small molecules of digestedfood like glucose and amino acids pass into the
epithelial cells and then through the wall of the capillaries in the villi, entering the bloodstream. The blood
carries these nutrients to the liver via the hepatic portal vein.
● Fatty Acids and Glycerol:While some fatty acids andglycerol enter the blood capillaries of the villi, a
substantial proportion combines to re-form fats within the intestinal epithelium. These fats then enter the
lacteals, and their fluid flows into the lymphatic system.
● Vitamins and Mineral Salts:Water-soluble vitaminsmay diffuse into the epithelium, while fat-soluble
vitamins are carried within microscopic fat droplets. Mineral salts are likely absorbed through active transport,
with calcium ions requiring vitamin D for effective absorption.
xperiments:
E
Experiment 2 - The Action of Salivary Amylase on Starch:
In this experiment, saliva (or amylase solution) is used to demonstrate the conversion of starch into sugar.
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● Two test tubes, one containing unboiled saliva (or amylase solution) and the other containing boiled saliva (or
amylase solution), are mixed with a starch solution.
● The test tubes are tested for the presence of sugar using Benedict's solution, which forms a red or orange
precipitate in the presence of reducing sugar.
● Results show that the unboiled saliva (or amylase) digests the starch into sugar, while boiled saliva (or
amylase) does not, suggesting that it's an enzyme responsible for the conversion.
xperiment 3 - Modelling the Action of Amylase on Starch:
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In this experiment, Visking tubing is used to model the digestion of starch.
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● Visking tubing is filled with a starch solution and amylase (or saliva), and the contents are surrounded by
distilled water.
● After a certain period, samples from the Visking tubing and the surrounding water are tested for the presence
of starch and reducing sugar.
● The results indicate that starch is digested into reducing sugar and that reducing sugar can diffuse from the
tubing into the surrounding water, demonstrating the process of digestion and absorption.
xperiment 4 - The Action of Pepsin on Egg White Protein:
E
T
● his experiment demonstrates the action of pepsin on protein using egg white suspension.
● Four test tubes are labeled A, B, C, and D and filled with egg white suspension, pepsin solution, and/or dilute
hydrochloric acid (HCl) as specified.
● The tubes are placed in warm water, and after a period, the contents are observed.
● Tube C goes clear, indicating that pepsin digests egg protein into soluble products only in an acidic
environment. The other tubes do not go clear, confirming the role of pepsin in the digestion process.