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Renal Physiology

LH (4)

Prof. Mohamed Fathelbab


Physiology Department
The loop of Henle
and countercurrent multiplication

Countercurrent multiplication
– Between ascending and descending limbs of
loop
– Creates osmotic gradient in medulla
– Facilitates reabsorption of water and solutes
before the DCT
– Permits passive reabsorption of water from
tubular fluid
TUBULAR REABSORPTION
TUBULAR REABSORPTION FROM THE LOOP OF
HENLE RESULTS IN 10% OF WATER

BEING REABSORBED FROM THE DESCENDING


LIMB, 30% OF POTASSIUM IONS, 20% OF SODIUM,
AND 35% OF CHLORIDE FROM THE ASCENDING
LIMB.
Function of the vasa recta
Removes solutes and water
– Balances solute reabsorption and osmosis in the
medulla
REABSORPTION IN LOOP OF HENLE
REABSORPTION IN LOOP OF HENLE

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