Across

1. Should be checked before administration of antibiotics (3 words)

9. Caused by prior exposure to an antibacterial (2 words)
10. Introduced during World War II
11. Drugs that inhibit the growth of bacteria
12. Resistance to antibacterial drugs that have similar actions (2 words)
Down
2. Antibody proteins such as IgG and IgM
3. Infections acquired when in a health care facility (2 words)
4. Bacterial resistance that may occur naturally (2words)
5. Toxicity of drugs in the kidneys
6. Drugs that kill bacteria
7. The first penicillinase-resistant penicillin
8. Occurrence of a secondary infection when the flora of the body are
disturbed
9. Substances that inhibit bacterial growth or kill bacteria
 Matching Type:
1. Penicillin G a. First-generation
cephalosporin
2. Amoxicillin b. Second-generation
cephalosporin
3. Oxacillin c. Third-generation
cephalosporin
4. Piperacillin-tazobactam d. Fourth-generation
cephalosporin
5. Ancef e. Basic penicillin
6. Cefaclor f. Penicillinase-resistant
penicillins
7. Cefdinir g. Broad spectrum penicillin
8. Cefepime h. Extended-spectrum
penicillins
9. Amikacin i. macrolides
10. Clindamycin j. lincosamides
11. Tigecycline k. Ketolides
12. Erythromycin l. lipopeptides
13. Telithromycin m. tetracyclines
14. Azithromycin n. glycylcyclines
15. Doxycycline o. Aminoglycosides
16. Ciprofloxacin p. fluoroquinolones
17. Clarithrom
18. Mocifloxacin
19. daptomycin

Case Study

Antonia, a 24-year-old woman with medical history of asthma, migraines, and seizure
disorder comes
to the health care provider complaining of a productive cough, fever, and flulike
symptoms. Her sputum
culture is positive for Pseudomonas aeruginosa. Levofoxacin 500mg/d for 10 days
has been prescribed.
1. To which drug class does levofoxacin belong, and what is the
mechanism of action?

2. What side effects should the nurse educate the patient about?
3. What adverse reactions are associated with this medication?

4. Are there any precautions regarding levofloxacin for this patient?

Pedring is a 38 y.o. construction worker and had been diagnosed of tuberculosis. He

had been prescribed several medication for PTB for 6 months. His prescriptions
includes rifampicin, isoniazid, pyrazinamide, ethambutol and streptomycin.
1. Give the action of each of the drugs for Pedring.

2. What are the adverse effects of each drugs?

3. What patient teaching can you advise Pedring while taking each drug?
 What are the stages in the replication cycle of a virus?

1. Give the mechanism of action, routes of administration of the following drugs:

a) Efavirenz

b) Maraviroc

c) Raltegravir

d) Ritonavir

e) Zidovudine

f) Acyclovir
2. Problem Solving:
a. The recommended dose of acyclovir for immunocompetent children under 12
years is 15-20 mg/kg/ day divided in three doses. What is the safe dose range for
a child who weighs 44 pounds?

b. A 35-yearl old male patient has been HIV positive for 12 years. His medications
includes zidovudine. When being interviewed by the nurse during a routine clinic
appointment, he complains of declining vision, headaches, and daily temperature
elevations. Physical examination findings include multiple enlarged lymph nodes
and several white retinal patches.

 What complications of HIV is likely to be occurring?

 What is the treatment of choice if the patient develops CMV retinitis?

 What are the patient teaching for clients who are receiving antivirals for CMV?
 List down fungal
infections (systemic and
local) 1.
2.
1.
2.
3.

Explain the life cycle of a Plasmodium (in not less than 50 words)

List down the type of helminths and its mode of entry into the body.
1. -
2. -
3. -
4. -
5. -

DRUG DOSE CALCULATION:

1. The drug handbook states that the therapeutic dose of metronidazole is 7.5mg/kg
every 6 hours. A child is prescribed metronidazole (flagyl) 500mg in 100ml D5W every 6
hours. The child is 5’6” and weighs 145 lbs. Is the dose safe and effective? Show the
exact dosage.

2. A prophylactic dose of 1g metronidazole IV is ordered for a patient who weighs

176 lbs. The recommended dose is 15 mg/kg. Is the dose safe? Show the exact dosage
COMPLETION
1. The term for fungal disease is .
2. Superficial means .
3. Systemic means .

MATCHING TYPE:
1. Skin a. Tinea capitis
2. Foot b. Tinea corporis
3. Groin c. Tinea cruris
4. Scalp d. Tinea pedis

1. What are the causes of cancer?

2. What are the types of cancer?

1. The receptors on the cell membrane can
activate tyrosine kinases, which then turn on signal transduction
pathways promoting cell division.
2. is a method of communication that allows
events, conditions, and substances outside of the cell to influence
it.
3. Tyrosine kinases are a family of enzymes that activate other
substances by adding a phosphate molecule, a process known as
.
4. for cell division are substances that enter
the nucleus and signal the cell that mitosis is needed.
5. are part of a family of proteins that, when
active, stimulate the cell to move through the cell cycle.
6. A(n) is a large complex of proteins in cell
◻uid (cytoplasm) and the cell nucleus that regulates protein
expression and the of damaged or old proteins within
the cell.
7. therapy for cancer takes advantage of
biological features, such as
, , or other molecular proteins of cancer
cells that either are not present or are present in much smaller
quantities in normal cells.