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    The document discusses the treatment of amebiasis, an infection caused by the parasite Entamoeba histolytica that ranges in severity from asymptomatic to fatal. Amebiasis is a global health problem found worldwide, not just in tropical areas, and is transmitted from person to person. It can cause acute dysentery or chronic recurrent diarrhea and sometimes remains latent. While amebic dysentery is more common in tropical areas and causes more severe symptoms, in the US amebiasis is usually milder and may cause constipation rather than severe diarrhea. An understanding of the host-parasite relationship is important for discussing treatment of this complex condition.

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    The document discusses the treatment of amebiasis, an infection caused by the parasite Entamoeba histolytica that ranges in severity from asymptomatic to fatal. Amebiasis is a global health problem found worldwide, not just in tropical areas, and is transmitted from person to person. It can cause acute dysentery or chronic recurrent diarrhea and sometimes remains latent. While amebic dysentery is more common in tropical areas and causes more severe symptoms, in the US amebiasis is usually milder and may cause constipation rather than severe diarrhea. An understanding of the host-parasite relationship is important for discussing treatment of this complex condition.

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    8 views1 page

    First Page PDF

    Uploaded by

    MAnugrahRizkyP
    The document discusses the treatment of amebiasis, an infection caused by the parasite Entamoeba histolytica that ranges in severity from asymptomatic to fatal. Amebiasis is a global health problem found worldwide, not just in tropical areas, and is transmitted from person to person. It can cause acute dysentery or chronic recurrent diarrhea and sometimes remains latent. While amebic dysentery is more common in tropical areas and causes more severe symptoms, in the US amebiasis is usually milder and may cause constipation rather than severe diarrhea. An understanding of the host-parasite relationship is important for discussing treatment of this complex condition.

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    The Treatment of Amebiasis

    FREDERICK STEIGMANN, M.D.*

    WILLIAM H. SHLAES, M.D. **

    Amebiasis, a disorder ranging from "asymptomatic" to fatal in


    character, illustrates the wide biological variations possible in the host-
    parasite relationship. Since the protean clinical manifestations of amebiasis
    stem from this biologic complexity of host-parasite interaction, it would
    appear advantageous to review briefly some of these complex factors before
    discussing the therapy of this condition.
    Amebiasis is today a health problem throughout the entire world-
    not only in tropical or subtropical areas but also in cold climates.! It is an
    insidious disease, transmitted only from man to man and does not require
    an intermediate host. It tends to persist despite various therapeutic regi-
    mens, and may run the whole gamut from acute fulminating dysentery
    through chronic recurrent diarrhea. Occasionally it may remain latent.
    Amebiasis denotes that the body is infested with Entamoeba histoly-
    tica. Amebic dysentery, a form not very common in the United States,
    is only one of its manifestations. It is the more serious form of this disease
    and occurs frequently in the tropics where amebiasis, in general, is more
    frequent and is accompanied by more severe clinical symptoms. In the
    United States amebiasis is seen mostly in its milder form, which is not
    associated with severe diarrhea but, at times, rather with constipation. It
    has a low mortality but a high morbidity.

    ETIOLOGICAL CONSIDERATION

    An understanding of the etiological relationship of amebiasis to dysen-

    From the Departments of Medicine, Therapeutics and Gastroenterology of the Cook


    County Hospital and the Departments of Internal Medicine of the University of
    Illinois College of Medicine and the Chicago Medical School, Chicago, Illinois
    * Attending Physician and Director of Therapeutics and Gastroenterology, Cook COllnty
    Hospital; Clinical Associate Professor of Medicine, University of Illinois College
    of Medicine
    ** Assistant Professor of Medicine, Chicago Medical School
    159

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