Thyroid Function Test 2022

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Thyroid function test

Butterfly shaped gland in the neck

T3 , T4……from TSH

Pare-follicular(C-cells) secrete Calcitonin (Ca met.)


Regulation
Hypothalamus secrete TRH

TRH provokes Anterior Pituitary to produce TSH

(-)

TSH provoke thyroid gland to produce T3 & T4


Hyperthyroidism
TSH low….. High T3 & T4
Hypothyroidism
Cretinism & Myxedema

• Primary………….TSH high….T3 &T4 low

• Secondary……..low TSH…low T4
Symptoms of Symptoms of
hyperthyroidism
hypothyroidism GRAVES disease
• Goitre Exopthalmos
• Cold intolerance. Heat intolerance
• Depression Mild tremors
• Bradycardia Tachycardia
• Weight gain Anxiety
• Body odor
• Menstrual irregularity
• Menstrual irregularity
Blood tests & Normal values.
• TSH…… 0.3–4 mIU/l
• Total T3….. 60-200 ng/dl
• Total T4….. 77–155 nmol/l
• Free T3…..130-450 pg/dl
• Free T4…..0.9- 2.3 ng/ dl
• Anti-thyroid peroxidase (anti-TPO) antibodies.
• Thyroglobulin antibody.
• FNAc…….fine needle aspiration cytology
• Calcitonin…for carcinomas
• NON-INVASIVE….USG, CT scan

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