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  • Xray Mets Bone

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    Diyana Zaty
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    Bone metastases are frequently seen complications of cancer that are more common than primary bone tumors. They develop through tumor cells migrating to the bone marrow, invading the niche, and developing osteolytic or osteosclerotic lesions through two mechanisms. Key features on x-rays include the patient's age, with primary bone tumors rare under 5 or over 40 generally and metastases most common over 40; the location within bone; borders to determine growth rate; and signs of transition zones, periosteal reactions, matrix changes, and soft tissue components.

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    XRAY METS BONE

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    Bone metastases are frequently seen complications of cancer that are more common than primary bone tumors. They develop through tumor cells migrating to the bone marrow, invading the niche, and developing osteolytic or osteosclerotic lesions through two mechanisms. Key features on x-rays include the patient's age, with primary bone tumors rare under 5 or over 40 generally and metastases most common over 40; the location within bone; borders to determine growth rate; and signs of transition zones, periosteal reactions, matrix changes, and soft tissue components.

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    1 views28 pages

    Xray Mets Bone

    Uploaded by

    Diyana Zaty
    Bone metastases are frequently seen complications of cancer that are more common than primary bone tumors. They develop through tumor cells migrating to the bone marrow, invading the niche, and developing osteolytic or osteosclerotic lesions through two mechanisms. Key features on x-rays include the patient's age, with primary bone tumors rare under 5 or over 40 generally and metastases most common over 40; the location within bone; borders to determine growth rate; and signs of transition zones, periosteal reactions, matrix changes, and soft tissue components.

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    of 28

    FEATURES OF BONE

    METASTASIS
    .

    )
    BONE METASTASIS
    • Bone metastases are very frequently seen complications of cancer, more frequently seen than primary bone
    tumors.
    • Metastatic bone disease is generally divided into 2 categories as osteoblastic and osteolytic disease.
    PATHOPHYSIOLOGY OF BONE METASTASIS

    i. Migration of metastatic tumour cells within blood circulation


    ii. Invasion of bone marrow niche
    iii. Development within bone tissue through two mechanisms leading to osteolytic or osteosclerotic lesions.
    XRAY FEATURES OF BONE LESIONS
    1. AGE OF PATIENT

    • Patient age is of huge importance in


    suggesting a differential diagnosis of focal
    bone lesions.
    • Primary bone tumors are rare in < 5 years
    old and > 40 years old, with exception of
    myeloma and chondrosarcoma.
    • Metastasis are the commonest lesion over
    the age of > 40 years old.
    2. LOCATION
    LOCATION WITHIN THE BONE
    3. BORDERS OF LESION TO DETERMINE ITS GROWTH RATE
    RATE OF GROWTH
    RATE OF GROWTH
    4. ZONE OF TRANSITION
    4. ZONE OF TRANSITION
    5. PERIOSTEAL REACTION
    6. MATRIX
    7. SOFT TISSUE COMPONENT

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