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EXTERNAL GENITALIA:
A. MONS PUBIS
- Provides an adipose cushion over the
anterior symphysis pubis
- Protects the pelvic bones
B. LABIA MAJORA
- Positioned lateral top of the labia minor
- Covered by pubic hair
C. LABIA MINOR
- Consists of connective tissue, elastic fibers,
veins and sebaceous glands
- Protect the ext. genitalia and the distal
urethra and vagina
- Unite to form the fourchette, the vaginal
vestibule
D. CLITORIS
- 1-2 cm in size
- Located in the anterior position of the vulva
- Covered by a fold of skin called the prepuce
- Make up of erectile tissue, nerves and blood vessels
E. VAGINAL VESTIBULE
- Flattened smooth surface inside the labia
- Openings to the bladder (urethra) and the uterus (vagina), both arise
from the vestibule
- Consists of the vaginal orifice, the hymen, the fourchette, Skene’s and
Bartholin’s glands
• HYMEN
- Is a thin but tough, vascularization mucous membrane
- located at the vaginal orifice
• FOURCHETTE
- Is the ridge of tissue formed by the post. joining of the two
labia majora and labia minora
- sometimes cut during vaginal birth (episiotomy)
• SKENE’S GLANDS (PARAURETHRAL GLANDS)
- are located lateral to the urinary meatus on either side
- help lubricate the ext genitalia during intercourse
• BARTHOLIN’S GLANDS (VULVOVAGINAL GLANDS)
- Secrete mucus along with Skene’s glands during sexual
stimulation
- alkaline ph of Skene’s and Bartholin’s help improve sperm
survival in the vagina
F. PERINEAL. BODY / PERINEAL MUSCLE / PERINEUM
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INTERNAL GENITALIA:
A. UTERUS
Functions:
- To receive the ovum from the Fallopian tube
- To provide a place for the ovum to implant
- To offer nourishment and protection to the
growing fetus
- To expel the fetus when mature
4 Parts:
1. Body/corpus - uppermost portion
2. Fundus - between points of attachment of the
fallopian tubes
3. Isthmus - short segment between corpus and cervix
- cut during cesarean birth
4. Cervix - lowest part
- the junction of the canal at the isthmus is the internal cervical os
- the distal opening into the vagina is the external cervical os
B. UTERINE LAYERS
1. ENDOMETRIUM
- Inner mucous membrane layer that’s shed during menstruation
2. MYOMETRIUM
- 3 interwoven layers of smooth muscle, which are arranged in longitudinal, transverse, &
oblique directions - offers extreme strength to the uterus
3. PERIMETRIUM
- Outer layer that covers the body of the uterus and part of the cervix
- Adds strength and support
C. UTERINE NERVE SUPPLY
- Both afferent (sensory) & efferent (motor) nerves
D. UTERINE BLOOD SUPPLY
- Uterine arteries
- The uterus also receives blood from the ovarian arteries
E. UTERINE SUPPORT
BROAD LIGAMENTS - 2 fold of peritoneum that cover the front and back of the uterus and
extend to the pelvic sides
ROUND LIGAMENTS - 2 fibrous muscular cords that pass from the body of the uterus
near the attachments of the Fallopian tubes
F. VAGINA
- Vascularized musculomembranous tube that extends from the external genitalia to the
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uterus
- Functions as the organ of intercourse, channeling sperm to the cervix
- Expands with pregnancy to function as birth canal
- Act as uterine excretory duct for menses and other secretions
G. FALLOPIAN TUBES
- Each is about 10cm /12 cm long
4 layers:
1. Peritoneal
2. Subserous
3. Muscular- produces peristaltic motions that conduct the ova the length of the tube
4. Mucosal - act as lubricant to aid ova travel and also act as nourishment for the fertilized
egg; contains CHON, H2O, and salt
4 Portions:
1. Interstitial - proximal portion; 1 cm in length
2. Isthmus - next distal portion; 2 cm
- is the portion of the tube that is cut or sealed in tubal ligation
3. Ampulla - 3rd and longest portion of the tube; 5cm
- fertilization of an ovum takes place
4. Infundibular - 4th most distal of the tube
- 2 cm long and funnel shaped
- the rim of the funnel is covered by fimbriae (small hairs) that help guide the ova into the
tube
H. OVARIES
- 2 almond shaped glandular structures on
either side of the uterus, below and behind the
Fallopian tubes
- Produce mature and discharge ova
RELATED STRUCTURES:
FEMALE ACCESSORY GLANDS:
2. FEMALE PELVIS
- Supports and protects the reproductive organs
- Bones which compose the body pelvis: ILIUM,
ISCHIUM, PUBIS, SACRUM, COCCYX
FALSE
PELVIS
-
2. SCROTUM
- Pouch-like structure made up of skin, fasciae
connective tissue, and smooth-muscle fibers
- House the testes, epididymis, and the lower
portion of the spermatic cord
- Protects the testes and spermatozoa from high
body temperature
3. TESTES
- Are 2 oval-shaped glandular organs inside the
scrotum
- Seminiferous tubules produces spermatozoa
- Leydig’s cells produce testosterone, the primary male sex hormone
- Sperm can’t survive at body temperature; the testes are
suspended outside the body where the temperature is
approximately 1oF lower than body temperature
INTERNAL GENITALIA
1. EPIDIDYMIS
- Tightly curled, the length totals 6m
- Responsible for conducting sperm from the testis to the vas deferens or storing it
- Sperm are immobile as they pass through or stored here
- Takes at least 12-20 days for the sperm to travel the length of the epididymis and a total
of 64 days for them to reach maturity
2. VAS DEFERENS
- Also called DUCTUS DEFERENS
- Carries sperm from the epididymis through the inguinal
canal into the abdominal cavity where it ends at the
seminar vesicles into the ejaculatory ducts
- Blood vessels and the vas deferens together are referred
as SPERMATIC CORD
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3. EJACULATORY DUCTS
- Located between the seminal vesicles and urethra
4. URETHRA
- Extends from the bladder through the penis to the external urethral opening
- Serves as excretory duct for urine and
semen
5. SEMINAL VESICLES
- Secrete a viscous portion of the semen
that aids in spermatozoa motility and
metabolism because the fluid is alkaline
and sperm are more motile in an alkaline
fluid
6. PROSTATE GLAND
- Located just below the bladder
- Homologous to Skene’s glands in females
- Secretes an alkaline fluid that enhances
spermatozoa motility and lubricates the
urethra during sexual activity
7. BULBOURETHRAL / COWPER’S GLANDS
- 2 pea sized glands that lie beside the prostate and empty into the urethra
- Secrete an alkaline fluid that neutralized acidic secretions in the female reproductive
tract, thus prolonging spermatozoa survival
- The alkaline fluid and sperm combination is a thick, whitish secretion termed SEMEN
MENARCHE
- 1st menstruation period in girls
- May occur as early as 9 years and as late as age 17 and still be within normal limits
DIFFERENT MENSTRUAL CONCERNS
Amenorrhea
Dysmenorrhea
Metrorrhagia
Menorrhagia
Menopause
MENSTRUAL CYCLE
- Also termed FEMALE REPRODUCTIVE CYCLE
- Periodic uterine bleeding in response to cyclic hormonal changes
- Purpose is to bring an ovum to maturity and renew a uterine tissue bed that will be
responsive to its growth should it be fertilized
PHYSIOLOGY OF MENSTRUATION
4 STRUCTURES INVOLVED IN THE MENSTRUAL CYCLE:
1. HYPOTHALAMUS
- Releases LHRH / GnRH which initiates menstrual cycle
- Presence of estrogen represses the hormone
2. PITUITARY GLAND
- Under the influence of LHRH, the anterior lobe of the pituitary gland (adenohypophysis)
produces 2 hormones that act on the ovaries to further influence the menstrual cycle:
FSH - Responsible for maturation of the ovum
LH - becomes most active at the midpoint of the cycle and is responsible for ovulation
3. OVARIES
- Maturation of locates (4 million at present)
- Ovulation; every month, one of the follicles is
activated by FSH.
At maturity, it is visible on the surface of the
ovary as a clear water blister approximately 1/4
- 1/2 termed GRAAFIAN FOLLICLE
- The ovum is set free from the surface of the
ovary, a process termed OVULATION; ovulation
occurs on approximately 14th day before the
onset of the next cycle (subtract 14 days from
the
length of the menstrual cycle)
- The LH causes the ovary to produce
LUTEINIZING, a bright yellow fluid, instead of follicular fluid. This yellow fluid fills the
empty follicle, which is then termed CORPUS LUTEUM (yellow body)
SIGNS OF OVULATION:
• Mittleschmerz - slight discomfort in right / left iliac region
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HORMONES INVOLVED:
1. GnRH (APG) - initiates the menstrual cycle
•
FSH
- stimulate development of primordial follicles
into Graafian follicles
• LH
- responsible for ovulation
2. ESTROGEN
- secondary sex characteristics
- Fertile cervical mucus
- Maintains the endometrium
- Stimulates uterine contraction
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3. PROGESTERONE
- Prepares the endometrium
- Relaxes the myometrium
- Increases basal body temperature
- Infertile mucus
- Maintains pregnancy
SEX
Act of copulation / “coitus
SEXUAL RESPONSE CYCLE - Elevation of the testes
4 Stages of Sexual Response: - Increase BP, HR, RR
1. EXCITEMENT PHASE 2. PLATEAU PHASE
- Physical and psychological stimulus - Reached first before orgasm
- Arterial dilatation and venous - Women: formation of orgasmic platform,
constriction in the genital area increased nipple engorgement
Physiological changes in woman: - Men: full distention of the penis
- clitoris increase in size 3. ORGASM PHASE
- Lubrication - Discharge of accumulated sexual tension
- Vagina widens - Shortest stage
- Breast nipples become erect 4. RESOLUTION STAGE
- Increase BP, HR, RR - External and internal organs return to
Physiological changes in men: their uncrossed state
- Erection - Generally takes 30 min
- Scrotal thickening
FERTILIZATION
CONCEPTION / IMPREGNATION /
FECUNDATION
- Union of ovum and spermatozoon
- Fertilized egg is called ZYGOTE
OVUM - from ovulation to fertilization
ZYGOTE - from fertilization to implantation
EMBRYO - from implantation to 5-8 weeks
FETUS - From 5-8 weeks until term
CONCEPTUS - developing embryo / fetus and
placental structures throughout pregnancy
CAPACITATION
- Final process that sperm must undergo to be ready for
fertilization
- The sperm move toward the ovum
- Changes in the plasma membrane of the sperm head,
reveals the sperm - binding receptor sites
HYALURONIDASE
- Proteolytic enzyme
- Released by the spermatozoa and acts to dissolve the
layer of cells protecting the ovum
Normally, only one spermatozoon is able to penetrate the
cell membrane of the ovum. Once it penetrates the zona
pellucida, the cell membrane becomes impervious to other
spermatozoa.
After the spermatozoon penetrates the ovum, its nucleus is released into the ovum, its tail
degenerates and its head enlarges and fuses with the nucleus of the ovum. This fusion
provides the
fertilized ovum, called a zygote with 46 chromosomes. The spermatozoon and ovum each
carried 23 chromosomes (22 autosomal and 1 sex chromosome)
https://youtu.be/_5OvgQW6FG4
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C. PLACENTA
- Latin for pancake
- is formed by the union of chorionic villi and decidua basalis
- Contains 15 - 2-/30 subdivisions called COTYLEDONS
- Maturity: 12 weeks/3 months; functions most effectively through 40 - 41 weeks
- Weighs 400-600 gm; 1/6 of the weight of the baby; measures from 15-20cm in diameter
and 2-3cm in depth at term
2 parts:
Maternal side - has a rough surface
Fetal side - shiny and gray
MECHANISMS OF PLACENTA
A. SCHULTZ’ mechanism
- fetal side goes out first
- Most common; 80% of deliveries
B. DUNCAN’s mechanism
- 20%
FUNCTIONS OF THE PLACENTA
1. Respiration, circulation
- Umbilical vein - carries oxygenated blood
- 2 Umbilical arteries - carry deoxygenated blood
- Foramen ovale - septal opening between the atria of
the fetal heart
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- Ductus arteriosus - connects the pulmonary artery to the aorta, allowing blood to shunt
around the fetal lungs
- Ductus venous - carries oxygenated blood from the umbilical vein to the inferior vena cava
bypassing the liver
2. Nutrition
- supplies the fetus with CHO, H2O, fats, CHON, minerals and inorganic salts
3. Protection
- transfers passive immunity via maternal antibodies (IgG)
4. Excretion
- it carries end products of fetal metabolism to the maternal circulation for excretion
5. Endocrine function
- produces hormones
• HCG - first hormone produces
• Estrogen - hormone of women
- primarily Estriol
- contributes to the mother’s mammary gland development
- stimulates uterine growth to accommodate the developing fetus
• Progesterone - hormone of mothers
- necessary to maintain the endometrial lining of the uterus during pregnancy
- reduce the contractility of the uterine musculature during pregnancy, which prevents
premature labor
• HPL / Human Chorionic Somatomammotropin
- Growth promoting and lactogenic properties
- Regulates maternal glucose, CHON, and fat levels
D. UMBILICAL CORD
- Originates from the amnion and chorion
- Serves as the lifeline from the embryo to the placenta; provides circulatory pathway
- About 53 - 55 cm (21inch) in length at term
3 Parts:
1 vein
2 arteries
Wharton’s jelly - gelatinous substance that helps prevent kinking of the cord in uterus
(cord coiling / nuchal cord); gives the cord body and prevents pressure on the veins and
arteries
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1. Cardiovascular System
- One of the 1st systems to become functional in intrauterine life
- Single heart tube forming as early as the 16th day of life, beating as early as the 24th day
- Heart beat may be heard with a Doppler as early as the
10th - 12th week of pregnancy; 16th - 20th week with a stethoscope
2. Respiratory System
- 3rd week, respiratory and digestive tracts exists as a single tube
- End of 4th week, a septum begins to divide the esophagus from the trachea. At the same,
lung buds appear on the trachea
- Spontaneous respiratory movements begins as early as 3 months
- SURFACTANT, a phospholipid substance is formed and excreted by the alveolar cells at
about 24th week. This decreases alveolar surface tension on expiration, preventing alveolar
collapse
Surfactant has 2 components:
- 35th weeks - lecithin and sphingomyelin
- Ratio: 2:1
- With fetal lung movements, surfactant mixes with amniotic fluid
3. Nervous System
- Develops during 3rd and 4th week of life
- Neural plate (thickened portion of ectoderm) is apparent by 3rd week of gestation
- Brain waves can be detected on EEG by the 8th week
- By 24th week, the ear is capable of responding to sound; the eye exhibit a pupillary
reaction, indicating sight is present
4. Endocrine System
- They mature in intrauterine life
5. Digestive System
- Separated from the respiratory tract at about 4th week
- MECONIUM forms in the intestines as early as the 16th week. It consists of cellular
wastes, bile, fats, mucoproteins, mucopolysaccharides, and portions of the vernix caseosa
- Meconium is black or dark green (obtaining its color from bile pigment and sticky
- Sucking and swallowing reflexes are not mature until the fetus is about 32 weeks or the
fetus weighs 1500 gm
6. Musculoskeletal System
- Quickening - 1st fetal movements perceived by the mother
16th week - multiparous
20th week - primipara
- Fetus can be seen to move on ultrasound as early as 11th
week
7. Reproductive System
- Child’s sex is determined at the moment of conception
- Can be determined as early as 8 weeks by chromosomal
analysis
- Gonads form at about 6th week
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- Testes first form into the scrotal sac late in intrauterine life at the 34th - 38th week
8. Urinary System
- Rudimentary kidneys are present as early as the end of the 4th week
- Urine is formed by the 12th week and is excreted into the amniotic fluid by the 16th week
of gestation
- At term, fetal urine is being excreted at the rate of 500 ml/ day
9. Immune System
- IgG maternal antibodies cross the placenta into the fetus primarily during the 3rd
trimester of pregnancy, giving a fetus temporarily passive immunity against diseases for
which the mother has antibodies
- The level of passive IgG immunoglobulins peaks at birth and then decreases over the next
9 months
10. Integumentary System
- Skin covered by soft downy hairs (lanugo), and a creamcheese like substances Vernix
Caseosa - secreted by sebaceous glands, important for lubrication, provide warmth, and
keeping skin from macerating.
1. NAGELE’s Rule.
- Count back 3 calendar months from the 1st day of LMP then add 7 days.
- e.g. Oct 5 , ---> 10-3, 5+7
=. 7. 12
July 12
2. DATE OF QUICKENING
Primigravida:
- Date of quickening + 4 months and 20 days = EDC Multigravida:
- Date of quickening + 5 months and 4 days = EDC
First three months = +9 +7
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AGE OF GESTATION
1. MC DONALD’S rule
- uses fundal height to determine duration of pregnancy
- Measurement is made from the notch of the woman’s
symphysis pubis to over the top of the
uterine fundus as the woman lies supine
- Typically, the distance form the fundus to symphysis
pubis in centimeters is equal to the week of
gestation between 20th - 31st week
- FH x 8/7 = AOG
- Mc Donald’s rule becomes inaccurate during the 3rd
trimester of pregnancy
- BASELINE - refers to the average rate of the fetal heartbeat per minute
- SHORT-TERM VARIABILITY / BEAT-TO-BEAT VARIABILITY small changes in rate that
occur from second to second
- LONG-TERM VARIABILITY - the differences in heart rate that occur over the 20-minute
time period
- Rhythm strip requires the mother to remain in a fixed position for 20 minutes
B. NON-STRESS TEST (NST)
- Measures the response of the FHR to fetal movement
- The woman pushes a button attached to the monitor whenever she feels the fetus move
- Fetal movement typically results in an increase in FHR of about 15 beats/min
- This increase should be sustained for about 15 seconds and turn to baseline or average
when fetus quiets down
- Absence of an increase in FHR with movement is highly suggestive of fetal
hypoperfusion / fetal hypoxia
- Non-stress test is usually done for 10-20 minute (20-40)
- The test is REACTIVE if two accelerations of FHR (15 beats or more) lasting for 15 seconds
occur after movement within the chosen time period. NON-REACTIVE if no accelerations
occur with the fetal movements
C. STRESS TEST / CONTRACTION STRESS TEST / OXYTOCIN
CHALLENGE TEST (OCT)
- Method of evaluating fetal ability to withstand decrease O2 supply and the physiologic
stress of an oxytocin - induced contractions before true labor begins
- IV oxytocin is administered, usually starting at 0.5mU/min at 15-20 min intervals until
three high quality uterine contractions are obtained within 10 minutes
- Can be used at 32 - 34 week gestation
D. NIPPLE STIMULATION STRESS TEST (breast selfstimulation)
- Carries the risk of hyper stimulation or embarrassment because it can’t be controlled if
there’s hyper stimulation
- May require nipple rolling or application of warm washcloths to one nipple
- Induces contractions by activating sensory receptors in the areola, triggering the release
of oxytocin by the posterior pituitary gland
- Exhibits the same reactive pattern as the reactive NST result and the same pattern as the
abnormal OCT result
3. BIOPHYSICAL PROFILE
- Assesses several variable
Fetal breathing movements
Fetal body movements
Fetal muscle tone
Fetal amniotic fluid volume
Fetal heart rate reactivity
Placental grade
- Each variable is scored as 0 - 2, with 0 indicating abnormal finding and 2 indicating a
normal finding; some institutions use a scoring system of 0, 1 and 2; total score is then
calculated
- This profile is commonly referred to as the FETAL APGAR SCORE because scoring is
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- Alpha-fetoprotein begins to rise at 11 weeks gestation, then steadily increases until term
- Elevated maternal serum AFP (MSAFP) level suggest a neural tube defect or other neural
tube anomaly (open spinal/abdominal defect) - open body defects
- Decrease MSAFP levels are associated with Down Syndrome
- Definitive diagnosis requires ultrasound and amniocentesis
12. TRIPLE SCREENING
- Involves a blood sample that tests 3 parameters: Maternal serum for alpha fetoprotein,
unconjugated estriol, HCG
13. CHORIONIC VILLI SAMPLING (CVS)
- Involves removal and analysis of a small tissue specimen from the fetal portion of the
placenta to determine the genetic make-up of the fetus
- Done at 10-12 weeks of pregnancy
- COELOCENTESIS- is an alternative method to remove cells for fetal analysis; transvaginal
aspiration of fluid from the extra embryonic cavity
- Complications: carries the risk of spontaneous abortion, infection, hematoma, and
intrauterine death
14. AMNIOCENTESIS
- Refers to a needle insertion into the uterus trans
abdominally to aspirate amniotic fluid for analysis
- Can be performed as early as 12 - 13th week of
gestation, when uterus has moved into the
abdominal cavity
- Requires only 1 ml of fluid for analysis
- Is indicated for women aged 35 and older and
women with family history of chromosomal /
neural tube defects or inborn errors of metabolism
USED FOR ASSESSMENT, DX, AND
EVALUATION
- Amniotic fluid color
Normal - color water
Slightly yellow tinge - late in pregnancy
Strong yellow color - blood incompatibility
Green color - meconium staining
-Lecithin/Sphingomyelin ratio 2:1
- Phosphatidyl glycerol & desaturated phosphatidyl - choline (present only with mature
lung function)
- Bilirubin determination - analyzed if a blood incompatibility is suspected
- Chromosome analysis - few fetal skin cells are always present in amniotic fluid. These
cells many be cultured and stained for karyotyping
- Inborn errors of metabolism
- Alpha-fetoprotein
15. PERCUTANEOUS UMBILICAL BLOOD SAMPLING
(PUBS)
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DIAGNOSIS OF PREGNANCY
SIGNS AND SYMPTOMS OF PREGNANCY
PRESUMPTIVE
- Subjective evidence / could be signs of pregnancy
A. AMENORRHEA
- In about 80% of clients or
- Slight, painless spotting of unknown cause in early gestation (20%)
- Due to suppression of FSH
B. BREAST CHANGES (2 weeks)
- Enlargement and tenderness
- A feeling of fullness, tingling or tenderness in breasts because of increase stimulation of
breast tissue by the high estrogen in the body
- Breast size increases, because of hyperplasia of the mammary alveoli and fat deposits
- The areola darkens in color, and its diameter increases from 3.5 to 5 or 7.5cm (1.5 - 2-
3inch)
- Vascularity of the breast increases, blue veins may become prominent over the surface of
the breasts
- Sebaceous glands of the areola enlarge and become protruberant to keep the nipple
supple and help prevent from crackling and drying during the lactation
- By 16th week, colostrum, can be expelled from the nipples MGT: relieved by wearing a
well-fitting bra
C. NAUSEA, VOMITING / MORNING SICKNESS (2 weeks)
- Most prevalent during the 1st trimester, most common in early morning
- Systemic reaction to increase estrogen levels or decrease glucose levels
MGT: Dry toast / crackers before arising in the morning; avoid greasy / fatty foods; avoid
highly seasoned foods; eat small, frequent meals
D. URINARY FREQUENCY AND URGENCY (3 weeks)
- Caused by the pressure of the enlarging uterus on the bladder within the 1st trimester
before uterus rises out of the pelvis
MGT: Decrease fluid intake in the evening
Avoid caffeine and tea
Void as soon as the urge is felt
Teach how to perform Kegel’s exercise
Report signs of UTI at once
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POSITIVE
- Absolute evidence
A. FHR
Funic soufflé
Uterine soufflé
B. FETAL MOVEMENT
- When felt by the examiner, after the 16th week but usually about 5 months
C. ULTRASONOGRAPHY
- Maybe detected as early as the 6th week of gestation, although usually done at 16 - 18
weeks
D. ROENTGENOGRAPHY
- X-ray of fetal skeleton; usually done at 14th - 20th week
PHYSIOLOGIC CHANGES OF PREGNANCY
A. REPRODUCTIVE SYSTEM
- Uterine changes
- “Practice contractions” - Braxton Hick’s contractions
- Amenorrhea
- Cervical changes
- Vaginal changes
- Ovarian changes
- Changes in the breasts
B. INTEGUMENTARY SYSTEM
- Hyperactive sweat and sebaceous glands
- Hyperpigmentation
- Palmar erythema & increase angiomas
- Increase hair & nails growth
C. RESPIRATORY SYSTEM
- Increase vascularization of the respiratory tract caused by increased estrogen levels
- Shortening of diaphragm caused by the enlarging uterus
- Increase tidal volume causing slight hyperventilation
- Slight increase (2 bpm) in respiratory rate
D. METABOLIC
- Increase water retention caused by higher levels of steroids sex hormones
- Decrease serum CHON levels
- Increase intra-capillary pressure and permeability
- Increase levels of serum lipids, lipoproteins, and cholesterol
- Increase iron requirements
- Increase CHO needs
- Increase body temperature
Weight gain 25 - 30 lb (11.3 - 13.6 kg)
Allowable weight gain in pregnancy
1st trimester - 2-4 lb
2nd trimester - 11 - 13 lb
3rd trimester - 11 - 13 lb
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E. CARDIOVASCULAR
Heart
- Increase cardiac workload > increase cardiac output > left ventricular hypertrophy >
palpitations, increase heart rate
- Stroke vol >increase 10 - 30%
- Heart displaced up and the left, PMI shifts about 1.5 cm to the left
Blood
- Increase iron demand
- Increase water retention
- Decrease blood viscosity and increase blood flow
->pulmonic and apical systolic murmurs
- Increase progesterone > increase fibrinogen > increase clotting factor XII, IX, and X at
term
Blood Volume
- Circulating blood volume increase by 30-50% by water and Na retention approximately
1,500 cc Blood Pressure
- Brachial artery pressure highest when sitting; lowest when at lateral recumbent position
- 2nd & 3rd trimester - increase relaxin > vasodilation,
muscle relaxation and decrease muscle tone > decrease peripheral resistance > decrease BP
- Venous compression > increase venous stasis > pronicity to thrombosis
- BP is lowest on the 2nd trimester because of pseudoanemia
- Compression of iliac veins leads to.
- Supine hypotensive syndrome
- increase hydrostatic pressure in leg veins > varicose veins and dependent edema
F. GASTROINTESTINAL
- Stomach displaced upward > increase reflux of acids in the lower esophagus > heartburn
(pyrosis) and flatulence - related to increase HCG, progesterone
- Increase progesterone > decrease GI motility and emptying > tendency for N&V
- EPULIS OF PREGNANCY due to estrogen
- Thicker bile secretion due to progesterone
- PTYALISM due to increase level of estrogen
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G. URINARY SYSTEM
- Diuresis > pressure of enlarging uterus to bladder in 1st trimester
- Relieved when uterus rises out of the pelvis in 3-4 months but returns with LIGHTENING
(2 weeks before onset of labor)
H. SKELETAL SYSTEM
Postural Changes
- Lumbosacral curve increases accompanied by a compensatory curvature in the
cervicodorsal region
- Characteristic posture in pregnancy: Backward tilt of torso to balance the weight of the
enlarging abdomen > strain on back and thigh muscles and ligaments > back pains and
cramps later in pregnancy
- Waddling-Gait of Pregnancy - duck-like movement of pelvis when walking due to pelvic
instability caused by the enlarging abdomen and relaxation of sacro-iliac joint and
symphysis pubis
- Enlarging uterus > anterior abdominal wall stretching > umbilical stretched > DIATASIS
RECTI
I.ENDOCRINE SYSTEM
- The major endocrine gland during pregnancy is the
PLACENTA
- Increase BMR (up to 25% at term)
- Increase iodine metabolism from slight hyperplasia of the thyroid gland
- Slight parathyroidism
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- Production of PROLACTIN
- ESTROGEN & PROGESTERONE > GnRH suppression > decreases gonadotrophic
hormones > no ovulation
- Increase HCG > (+) pregnancy test > prolongs life of corpus luteum > continued
production of estrogen and progesterone > continued vascularity of endometrium > support
life of embedded embryo / fetus
- Increase HPL detectable as early as 3 weeks and found in the maternal blood by 6th week
> decrease ability of the mother to use insulin (anti-insulin effect) > increase maternal
serum glucose supply to support the fetus & placenta > may cause GESTATIONAL
DIABETES
- Increase maternal cortisol / steroids > also has anti-insulin effect > increase maternal
serum glucose supply to support the fetus and placenta > may contribute to development of
Gestational DM
- Increase OXYTOCIN (later part of pregnancy) > stimulates the milk let-down reflex for the
release of milk after delivery of the baby and stimulates labor contractions to occur at term
J. IMMUNOLOGIC SYSTEM
- Only maternal IgG cross placental barrier to provide the baby with antibodies in the early
neonatal period
- IgA is secreted in colostrum providing baby with additional gastrointestinal protection
during
breastfeeding
- Fetal immune system develops as early as the 7th week and antigen recognition by 12th
week
- Fetus develops all types of immunoglobulins by 12th week, except IgA with highest
amount at term before delivery
PSYCHOLOGICAL / EMOTIONAL RESPONSES TO PREGNANCY
1. AMBIVALENCE
- Refers to the interwoven feelings of wanting and not wanting that always exist at high
levels
- Normal response in both the woman and her partner
- Lack of knowledge of or preparation for parenthood and children may also contribute to
ambivalence
2. GRIEF
- Commonly occurs as a result of changes in the woman’s role
3. NARCISSISM
- Self-centeredness / egocentrism
- Generally an early reaction to pregnancy
- Occurs as the woman becomes focused on herself and the changes occurring in her body
4. INTROVERSION / EXTROVERSION
- Some pregnant women become introverted during pregnancy, focusing entirely on their
bodies and
themselves
- Other women become extroverted - may increase their participation in activities and
appear more outgoing, they may view their expanding abdomen with a sense of fulfillment
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5. STRESS REACTION
- For some women pregnancy can be a time of stress
- The woman and her partner may view the pregnancy as interfering with his or her ability
to accomplish daily tasks
- Adequate support systems can help alleviate some of this stress and aid in adapting to the
pregnancy
6. EMOTIONAL LABILITY
- Mood changes occur frequently
- May be the result of the woman’s introversion and narcissism
- Additionally, hormonal changes, specifically increase
estrogen and progesterone contribute to this lability - Feelings are easily hurt by remarks
that would have been laughed off before
7. COUVADE SYNDROME
- Partner may experience discomforts such as nausea & vomiting, fatigue or weight gain,
similar to or possibly more intense than those that the pregnant woman experiences
- The more he is involved or attuned to the changes of his partner’s pregnancy, the more
symptoms he may experience
- These discomforts are normal and temporary and become problematic only if the partner
becomes delusional or emotionally disruptive
8. CHANGES IN SEXUAL DESIRE
- During the 1st trimester, most women report a decrease in libido because of the nausea,
fatigue and breast tenderness
- During the 2nd trimester, as blood flow to the pelvic area increases to supply the
placenta, libido and sexual enjoyment rise markedly
- During the 3rd trimester, it may remain high or decrease because of the awkwardness of
finding a comfortable position and increasing abdominal size
9. BODY IMAGE & BOUNDARY
- The way your body appears to yourself
- A zone of separation you perceive between yourself and objects or other people
DEVELOPMENTAL / PSYCHOLOGICAL TASKS OF
PREGNANCY
FIRST TRIMESTER - Acceptance of the Pregnancy
- “I am pregnant”
- Pregnancy confirmation may leave some couples with disbelief, shock, or amazement
- The woman & her partner must learn to accept the reality of the pregnancy
- Some couples experience some degree of ambivalence
- Feeling the fetus move or seeing the fetus on an
ultrasound can help the couple achieve acceptance
SECOND TRIMESTER - Acceptance of the Baby
- “I’m Going to Have a Baby”
- The woman and her partner work to accept the baby
- Acceptance of the baby refers to acknowledgment that the fetus is a distinct individual,
separate from the mother
- Feeling the fetus move or hearing its heartbeat demonstrates that the fetus is an active
being
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- The woman and her partner begin active preparations for the baby
- A good way to measure the level of a woman’s acceptance of the coming baby is to
measure how well she follows prenatal instructions
THIRD TRIMESTER - Preparation for Parenthood
- “I’m going to be a Mother”
- The couple work on preparing to become parents
- The couple begin to demonstrate “nesting” behaviors such as preparing the baby’s room,
shopping for
necessary baby items, and discussing names
- The couple may attend childbirth education classes
- The couple may review relationships with their own parents and engage in role-playing
and fantasizing about being a parent
MATERNAL DISCOMFORTS ASSOCIATED WITH
PREGNANCY
FIRST TRIMESTER MGT:
1. Nausea & Vomiting - Avoid constipation
2. Breast enlargement and tenderness - Avoid prolonged standing
3. Urinary frequency and urgency - Avoid constrictive clothing
4. Nasal stuffiness, discharge, or - Topical ointments / anesthetic
obstruction - Sitz baths or apply warm soaks
5. Leukorrhea - Lie on her side with feet slightly elevated
6. Fatigue - Re-insert external hemorrhoids, by
SECOND TRIMESTER placing patient in side lying / knee-chest
1, Heartburn / pyrosis position, using a lubricant and using only
2. Constipation gentle pressure
3. Hemorrhoids
4. Backache
- commonly known as PILES
5. Leg Cramps
- Overdilation of veins under the mucous
6. Ankle Edema
membrane in the rectal / anal area or
7. Shortness of breath
both related to the weakness in the walls
8. Fainting spells / Hypotension
of the rectum
9. Varicose veins
- Maybe INTERNAL or EXTERNAL and
10. Braxton Hick’s contractions
straining related bowel movement may
- are normal throughout the entire
cause bleeding
pregnancy, maybe more pronounced in
- Pressure on the pelvic veins by the
the latter part of pregnancy
enlarging uterus, which interferes with
11. Headache
venous circulation
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BATHING
- During pregnancy, sweating tends to
increase because the woman excretes
waste products for herself and the
fetus. She also has increase vaginal
discharges
- For these reasons, today, daily baths
or showers are recommended
- If membrane ruptures or vaginal
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bleeding is present, tub baths are contraindicated because there would be danger of
contamination of uterine contents
BREAST CARE
- Proper breast support promotes comfort, retains breast shape, and prevents back strain
- Washing the breast with clear water and no soap is recommended
- Gauze / breast pads may be needed if the woman’s secretions of colostrum is significant
DENTAL CARE
- Dental check-up early in pregnancy and routine examination and cleaning are
encouraged
- Nausea and vomiting, heartburn, and hypermedia of gums may lead to poor oral hygiene
and dental carries
- The fetus receives calcium and phosphorus from the pregnant patient’s diet, not form her
teeth
- Nutritious snacks, such as fresh fruits and vegetables, are recommended to avoid
excessive contact of sugar with teeth
PERINEAL HYGIENE
- Douching is contraindicated
- The force of the irrigating fluid could possibly enter the cervix and lead to infection
DRESSING / CLOTHING
- Clothes should be non-constrictive (impede lower extremity circulation)
- Low to mid heeled shoes are recommended to prevent backache and poor balance
- Comfort is the key
SEXUAL ACTIVITY
- Sexual behavior is usually unrestricted in complication free pregnancies
- Discouraged on the 36th week, it causes premature labor
IMMUNIZATIONS
- Immunizations with attenuated live viruses (mumps) shouldn’t be given during pregnancy
because of their teratogenic effect on the developing embryo
- Vaccinations with killed viruses (DPT) may be given
PRECAUTIONS
- Work site should be checked for potential environmental hazards, such as pesticides,
anesthetic gas, and heavy metals such as lead and mercury
- Work duties may have to be altered to avoid excessive
physical strain; rest periods need to be scheduled to avoid fatigue
- When riding in a care, seat belts should be worn low, under the abdomen
- If a long trip is planned, the woman should get out of the car every hour to walk around
- Airplane travel is permissible in places with well-pressurized cabins; some airlines have
restrictions for over 7 months pregnant
TERATOGENS
- Any factor, chemical or physical that adversely affects the fertilized ovum, embryo, or
fetus
- If the insult occurs when the main body systems are being formed (2nd - 8th week), the
fetus is vulnerable to injury
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- During the last trimester, the potential for harm decreases because all the organs of the
fetus are formed and merely maturing
MATERNAL INFECTIONS
-Collectively termed TORCH
• Toxoplasmosis
- A protozoan infection
- Spread most commonly through contact with cat stool or litter; also contracted by eating
undercooked meat
- Causes CNS damage, hydrocephalus, microcephalic, intracerebral calcification and retinal
deformities
- Therapy: Sulfonamides
• Rubella / German Measles
- Causes deafness, mental & motor retardation, cataracts, cardiac defects, retarded
intrauterine growth
(SGA), thrombocytopenia purpura, dental & facial clefts
- Frequency of defects is about 80% if infection occurs in the 1st 12 weeks of pregnancy,
54% at 13-14 weeks, 25% after
- 30% chance of spontaneous abortion/ stillbirth if the infection occurs in the 1st trimester
• Cytomegalovirus
- Causes severe brain damage, eye damage, deafness or chronic liver disease
- Can cause infection of the NB during birth from genital secretions or postpartum from
exposure to CMV- infected breast milk
- No treatment or vaccine
• Herpes simplex (genital herpes infection)
- If the infection takes place in the 1st trimester, severe congenital anomalies or
spontaneous abortion may occur
- If the infection occurs during the 2nd or 3rd trimester, there is a high incidence of
premature birth, intrauterine growth retardation, and continuing infection of the newborn
at birth
- TORCH screen still provides a quick way to assess the potential risk of teratogenic
infection in pregnant women and newborns
Other Viral Diseases:
SYPHILIS
- Treponema Pallidum, can extensively damage the fetus after the 16th - 18th week
- If left untreated beyond the 18th week of gestation, deafness, cognitive impairment,
osteochrondritis, and fetal death
- Benzathine Penicillin is often use safely during pregnancy
LYME DISEASE
- Caused by a spirochete (Borrelia Burgdorgeri)
- Is spread by the bite of a deer tick
- Infection in pregnancy results in spontaneous abortion or severe congenital anomalies
VACCINES
- Live virus vaccines, such as measles, mumps, rubella, and polio
- May transmit virus infection to the fetus
MEDICATIONS
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- The woman should not take any drug not specifically prescribed / approved by her
physician
- Prescription meds are categorized as A, B, C, D and X
- Category D drugs are those that have clear health risks for the fetus
- Category X are those that have been shown to cause birth defects and should never be
taken during pregnancy
- OTC meds also pose a risk to the fetus
- ASPIRIN and other drugs containing salicylate aren’t recommended during pregnancy
- HERBAL remedies aren’t recommended because their effects on pregnancy and the fetus
are unknown
SUBTANCE ABUSE
- Increases the risk of gross structural fetal defects
- Risk is greatest in the 1st trimester, during organogenesis
- NICOTINE causes:
Vasoconstriction
Alters maternal & fetal heart rate
PROTEIN
- Requirement exceeds pregnancy needs by 10g/day (from
46-50g to 60g daily)
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• Extra amounts of water are needed during pregnant or promote kidney function because
the woman must excrete waste produces for two
• 2 glasses of fluid daily over and above a daily quart of milk are recommended
FIBER
- Broccoli and asparagus, are a natural way of preventing constipation, because the bulk of
the fiber in the intestine aids evacuation
- Also has the advantage of lowering cholesterol levels and may remove carcinogenic
contaminants from the intestines
FOODS TO AVOID DURING PREGNANCY
- Foods with caffeine > has been associated with low birth weight
- Artificial sweeteners > use of saccharine is not recommended during pregnancy because it
is eliminated slowly from the fetal bloodstream
- Weight loss diets are contraindicated during pregnancy because they may lead to fetal
keto acidosis and neurologic defects
COMMON PROBLEMS AFFECTING NUTRITION
- Nausa & vomiting
- Cravings
- Pica
• An abnormal craving for non-food substances
• Is a symptom that often accompanies iron deficiency
- Pyrosis
- Hypercholesterolemia
• Increasing progesterone levels causes elevation of cholesterol
• This can lead to an increase risk for gallstone formation (cholelithiasis) and
cardiovascular disease