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But those outcomes aren’t in multiple patient popula-
inevitable, says John R. tions. To do so, the panel
McQuaid, PhD, who chaired members used 10 separate
a panel that created APA’s systematic reviews and meta-
new Clinical Practice Guide- analyses and followed the
line for the Treatment of best practices recommended
Depression Across Three by the National Academy
Age Cohorts. The guideline of Medicine (formerly the
provides research-based Institute of Medicine). When
recommendations for treat- reviewing the research, the
ing depressive disorders members considered four
CONTINUING EDUCATION including major depression, factors: the overall strength of
APA OFFERS NEW GUIDANCE subsyndromal depression and the evidence, the balance of
FOR TREATING DEPRESSION persistent depressive disorder a treatment’s benefits versus
BY KIRSTEN WEIR in children and adolescents, its harms or burdens, patient
adults, and older adults, using values and preferences, and
methods including psycho- applicability of the treatment.
therapy, pharmacotherapy “Most of the existing guide-
and alternative treatments. lines for depressive disorders
(Psychotic depression, the from other professional asso-
M
panel members noted, was ciations have focused mainly
ajor depression is the second-leading cause
outside the scope of this on pharmacotherapy,” says
of disability worldwide. In the United States,
guideline.) Elizabeth H. Lin, MD, MPH, a
an estimated 6.7% of adults and 1 1.7% of
“The big takeaway is that family medicine physician and
adolescents experienced at least one episode of major
there are effective options clinical professor at the Univer-
depression in the past year, according to the National
available to treat people with sity of Washington School of
Survey on Drug Use and Health by the U.S. Substance
depression,” says McQuaid, Medicine who was vice chair
Abuse and Mental Health Services Administration
a clinical psychologist with of the APA guideline panel.
(SAMHSA). Yet, too often, depression goes untreated,
the Department of Veterans Those who do take a more
exacting a significant human toll. Depression impairs
Affairs in San Francisco and a comprehensive look tend to
quality of life and interpersonal functioning, increases
professor at the University of focus on a specific population,
the risk of suicide and substance use disorders and
California, San Francisco. such as military members and
is associated with a raft of physical health problems,
The guideline-development veterans. The APA guideline
including an increased risk of heart disease, stroke,
panel included experts from panel took a much broader
diabetes and Alzheimer’s disease.
several countries besides approach, reviewing the
the United States and from a literature and making rec-
CE credits: 1 variety of disciplines, including ommendations for treating
Learning objectives: After reading this article, psychology (both clinicians depression in three groups:
CE candidates will be able to: and researchers) and children and adolescents, the
1 . Explain the goal and purpose of the APA Clinical Practice medicine (both psychiatrists general adult population, and
Guideline for the Treatment of Depression Across Three and primary-care physicians), adults 60 and older.
Age Cohorts. as well as methodologists and “This is truly the first guide-
2. Discuss the prevalence and impact of depression patient representatives who line to take such an in-depth
in the United States. could speak to the experience look at the rigorous research
3. Describe evidence-based recommendations for treating of living with depression. available in psychotherapy
MARTIN-DM/GETTY IMAGES
depression in children and adolescents, general adults Their goal was to create as well as pharmacotherapy,”
and older adults. a comprehensive guideline Lin says. “It will help prac-
For more information on earning CE credit for this article, that compared the efficacy of ticing clinicians and
go to www.apa.org/ed/ce/resources/ce-corner.aspx. various types of treatments researchers determine which
evidence-based treatments can for either recommending or not treatments, had greater harms or psychotherapy over interpersonal
contribute to the overall improve- recommending those treatments. burdens than other treatments or psychotherapy alone.
ment of depression.” For adolescents, the panel for which there was insufficient
A summary of the literature found more published evidence evidence that the treatment was RECOGNIZING
review and guideline follows. that met the inclusion criteria. The equivalent to other effective RESEARCH GAPS
guideline recommends the use treatments. For adolescents, the While the guideline covers a lot of
TREATING CHILDREN of cognitive-behavioral therapy guideline offers a conditional ground, the panel members found
AND ADOLESCENTS ABOUT CE (CBT) or interpersonal psycho- recommendation that patients KEY POINTS notable gaps in the science. Many
Depression is less common in therapy for the initial treatment and providers might consider studies didn’t meet the rigorous
children, with studies suggesting “CE Corner” is
of depression in adolescents. For alternative antidepressants,
1 methodological criteria set for
a continuing- This comprehensive
a prevalence rate of 0.4% to 2.5%, education article
clinicians considering medica- but recommends against the APA guideline inclusion in the reviews, McQuaid
the guideline panel reported. But offered by APA’s tion options for their adolescent use of clomipramine, imipra- compares the says, and some areas were thin
rates climb steeply as children Office of CE in patients with major depressive mine, mirtazapine, paroxetine efficacy of various on any research, high-quality or
Psychology. treatments for
approach their teenage years, disorder, the guideline recom- and venlafaxine because of the otherwise. “Particularly in the child
depression
with depression affecting 11.7% mends fluoxetine over other potential for increased suicide and makes
and adolescent population, and
To earn CE credit,
of adolescents. What’s more, after you read this
medications. There was not risk in youth taking these drugs. evidence-based the older adult population, there
depression in adolescents article, complete enough evidence, however, If fluoxetine is not an option, recommendations was far less scientific literature
appears to be rising. The rate at an online learning for the panel to determine the the guideline recommends for treating than for the general adult popu-
exercise and adolescents, adults
which adolescents experienced comparative effectiveness of psy- the clinician share decision- lation,” he says. “There’s also a
take a CE test. and older adults.
a major depressive episode chotherapy versus fluoxetine. making with a child psychiatrist real dearth of literature address-
Upon successful
increased 2.6% between 2005 completion of
If those treatments are ineffec- in addition to the provider, the 2 ing the needs of underserved
and 2014. tive, unavailable or unacceptable patient and the patient’s parents/ The guideline is populations, whether you define
the test—a score of
the first to take an
In younger children, boys and 75% or higher—you to the patient, the guideline sug- guardians or other family them by ethnicity, gender, sexual
in-depth look at the
girls are affected equally. After can immediately gests providers consider other members actively involved in his orientation, socioeconomic status
research on both
print your
puberty, however, young women treatment options, though the or her care. Depression affects more than 11% of adolescents. psychotherapy and or medical disability. There are
certificate.
are twice as likely as young men evidence for their effectiveness pharmacotherapy broad questions that need to be
to develop depressive disorders. To purchase the is less robust. Research on forms RECOMMENDATIONS major depression of 21% among combining CBT or interpersonal for depression, addressed about these groups.”
and makes
The depression rate among online program visit of psychotherapy other than CBT FOR ADULTS AND women, compared with 12% psychotherapy with a second- The guideline panel sees
recommendations
adolescent members of margin- www.apa.org/ed/ and interpersonal psychotherapy OLDER ADULTS among men. generation antidepressant. concerning specific
those gaps as a call to action.
ce/resources/ce-
alized populations is believed to was too limited for the panel to Depression is common among For the initial treatment An estimated 2.6% of older psychotherapies “We need more research to move
corner.aspx.
be significantly higher as well, be able to recommend a partic- young and middle-aged adults. of depression in adults, the adults experience depression. and medications. forward with our understanding
The test fee is
though the research on those ular type of intervention as an SAMHSA estimates that 6.7% guideline recommends either psy- Research has shown that late- of treating depression in those
groups is limited.
$25 for members
and $35 for alternative treatment. Information of U.S. adults—15.7 million chotherapy or second-generation life depression rates are higher
3 populations,” Lin says. “It’s a call
The guideline
While many children and nonmembers. was also lacking regarding alter- people—experience at least one antidepressants, which include among those with more medical to researchers, but also to policy-
identifies research
For more
adolescents live with depression, native medication options. major depressive episode each selective serotonin reuptake problems and with disabilities. gaps and notes makers and funders. We really
information, call
they are much less likely than In some cases, the guide- year. For 10.2 million of them, inhibitors (SSRIs) and sero- Evidence indicates that many that more work is need to address this.”
(800) 374-2721.
needed, particularly
adults to receive mental health line panel made a conditional that episode results in “severe tonin-norepinephrine reuptake older adults prefer psychosocial Limitations aside, the new
on treatments
treatment. In fact, less than 1% As an APA member, recommendation for treatments impairment.” As among adoles- inhibitors (SNRIs). There was not treatments for depression rather guideline offers a wealth of
for children,
of children and adolescents with take advantage of that were superior to control cents, women are twice as likely enough evidence to recommend than pharmacotherapy, the panel evidence-based recommenda-
adolescents,
your five free CE
depression receive outpatient conditions, but which were to experience depression as one psychotherapy treatment members note. older adults and tions for clinicians in psychology
credits per year.
treatment for depression. less effective than other active men, with a lifetime prevalence of over another, but in general, there As the initial treatment for underserved and across health care, McQuaid
Select the free
populations.
Unfortunately, the guideline online programs was support for behavioral ther- major depression in adults age says. In addition to the guideline
panel was unable to make a through your apy; cognitive therapy, CBT and 60 and older, the guideline rec- document itself, a complemen-
recommendation for treating MyAPA account.
SAMHSA estimates that 6.7% of U.S. mindfulness-based cognitive ther- ommends either group life review tary website provides additional
JUANMONINO/GETTY IMAGES
depression in children. The adults—15.7 million people—experience at apy; interpersonal psychotherapy; treatment or group CBT. When resources for health-care
members reviewed literature on psychodynamic therapies; and considering combined treatment, providers and patients, including
a wide variety of psychotherapies
least one major depressive episode each supportive therapy. For clinicians the panel recommends a com- materials for assessment, detailed
as well as pharmacotherapy, but year. For 10.2 million of them, that episode considering combination treat- bination of second-generation descriptions of treatments,
they found insufficient evidence results in “severe impairment.” ments, the guideline recommends antidepressants and interpersonal information for patients and their
Clinical Practice
adds. “It’s important for clini-
cians to have a collaborative
a National Combined Federal Campaign (CFC) Charity!
Guideline for discussion with patients about
families, case examples and a is something that many types the Treatment of psychotherapy and pharma-
resource page that includes links of medical providers are—and Depression Across cotherapy options for treating
to treatment manuals, books and should be—involved in, Lin adds. Three Age Cohorts depression, incorporating both
www.apa.org/
other relevant sites and sources. “Most of the people in society the patient’s preferences and
depression-
“We really hope this will be used who have depression don’t guideline/guideline. the provider’s expertise,”
broadly by health-care profes- initially seek care from psychol- pdf McQuaid says. “These guide-
sionals,” McQuaid says. ogists or psychiatrists, but from lines will support that shared
Indeed, depression treatment primary-care physicians or other decision-making.” ■
If you are a Federal Employee, you can now
RESEARCH-BASED ADVICE designate your gift to APF in the 2019 CFC Campaign.
CLINICAL PRACTICE GUIDELINES AT A GLANCE
APF’s CFC number is 31026
I
n 2010, APA adopted a process Stress Disorder, approved in 2017, the research is extensive, as in the
for producing clinical practice and the Clinical Practice Guideline case of depression.
guidelines for clinicians. The goal for the Behavioral Treatment of Obe- Clinical practice guidelines are
of these guidelines is to provide sity and Overweight in Children and designed not to be the last word on
research-based recommendations for Adolescents, approved in 2018. More treatment options, but rather to inform
If you would like your CFC gift to go to a specific fund at APF
the treatment of mental and behav- guidelines are underway, and the clinicians about best practices as they
ioral health conditions. Each guideline published guidelines will be updated engage in shared decision-making to (such as your Division fund), please designate APF on the CFC campaign forms.
is developed by an interdisciplinary approximately every five years. identify the right treatments for each
panel of experts and is based on a rig- Research on mental health and patient, Halfond adds. “Clinicians can
For more information contact misserow@apa.org or dial 202-336-5622.
orous review of the scientific literature behavioral treatments moves quickly, consider these guidelines together
for each topic. and the guidelines aim to provide a with their own expertise, keeping in
The Clinical Practice Guideline for summary of the most recent literature mind a patient’s culture, preferences
the Treatment of Depression Across on a topic, says Raquel Halfond, PhD, and values,” she says. “We hope this
Three Age Cohorts is the third clinical director of clinical practice guidelines will be a useful tool for clinicians to
RAWPIXEL/GETTY IMAGES
practice guideline developed by APA, at APA. “It can be hard for clinicians have in their toolbox, to be used as
following the Clinical Practice Guide- to take the time to pore over all of the part of an evidence-based practice in
line for the Treatment of Posttraumatic literature,” she says—especially when psychology.”
The rapid proliferation of new knowledge in psychology has placed renewed demands on
professional practitioners to keep pace with ongoing advances. Overall, knowledge may
remain current in professional psychology for as little as about 6-7 years, with more rapidly
diminishing durability in key areas of practice, such as psychopharmacology, child health,
forensics, substance use, or neuropsychology, among others (Neimeyer, Taylor & Rozensky,
2014). This means that, in the absence of a commitment to ongoing professional development,
many practitioners may begin to experience knowledge obsolescence even while they are still
in the early stages of their career (Neimeyer, Taylor & Rozensky , 2012).
BEST PRACTICES
In response, the field of professional psychology, together with practice. Benchmarking and self-assessment are two examples of
other allied health professions, have redoubled their efforts to educational practices that have arisen as mechanisms designed
formulate sets of “best practices” that can enhance learning and to facilitate quality assurance and ongoing professional develop-
the translation of that learning into practice (Institute on Medi- ment (Neimeyer and Taylor, 2014).
cine, 2010; Taylor and Neimeyer, 2017). The collective objective
of these best practices is to enhance the comprehension, reten- Benchmarking and Self-Assessment. Benchmarking refers
tion, and application of new knowledge in support of ongoing to the express comparison of one’s own work with the work of
professional competence. Some of these practices focus on the other professionals in the field. Benchmarking can be under-
value of adapting the learning strategies to individuals’ unique stood as the systematic process of evaluating work based on best
learning styles, presenting information multiple times utilizing practices and using evidence-based practice (EBP) to improve
different media, and providing opportunities for individuals’ input, performance. In a typical benchmarking procedure, a psychol-
application and behavioral rehearsal of the material, in addition ogist might be given videotapes of peers who are conducting a
to receiving peer, or instructor, review and feedback (Neimeyer procedure, such as a substance use screening. The videos are
& Taylor, 2014; Taylor and Neimeyer, 2017). pre-determined to depict varying levels of quality. They might
range from depicting relatively poor, informal questioning through
In addition to identifying current best practices, the allied health more thorough, systematic, structured interviews. The psychol-
fields have long dedicated themselves to the development and ogist is then asked to evaluate his or her screenings in relation
evaluation of novel mechanisms for enhancing new learning, as to those he or she has seen, and given information about key
well, drawing from a wide range of literatures with common objec- components that are present, and absent, in each of the video
tives. Research within the science-of-learning, adult education, “benchmarks.” Benchmarking provides an anchor against which
and performance enhancement literatures have been partic- psychologists can compare themselves, increasing the accu-
ularly productive in identifying and assessing novel methods racy of their self-assessment and incorporating elements of the
of learning and facilitating the translation of that learning into “higher” benchmarks into their own practice.
The precise mechanisms involved in triggering this translation into Overall, participants indicated that 65.5% of the CTC statements
practice are not fully known, but recent work has begun to address were implemented. Reflection scores correlated significantly with
them. Herbert, Lowe and Rappolt (cited in Lowe, Hebert & Rappolt, the number of planned CTC statements (r=.65, p<01), suggest-
2009), for example, wondered whether reflection alone at the end of ing the potential role of the CTC procedure in enhancing reflection
a new learning experience was sufficient to promote practice change, and, potentially, translation into actual practice. In addition, higher
or whether the express formulation of a commitment of change was reflection scores were related to the greater availability of opportu-
an essential element. Reflection has long been a key component of nities for audience response and the use of clinical case illustrations.
ongoing professional development programs, as reflected in the The researchers concluded that, “we found that reflection strongly
Mann et al., (2009) systematic review of reflection within continuing correlates with CTC” and that “continuing education “curricula that
medication education courses. In their study, Hebert et al. (2009) stimulate reflections may actually promote positive patient care
asked half of their participants to complete CTCs while the other half behaviors” (Ratelle et al., 2017, p. 166).
SUMMARY
Educators or learners who are interested in enhancing learning, the formulation of CTCs represents a relatively simple mechanism
and the translation of that learning into practice, may increase the for promoting reflection, anchoring expectations regarding adop-
retention and translation of material by incorporating CTCs into tion, and leveraging new learning into novel practice behaviors.
their programs. Although the overall effectiveness of CTCs as a Simple extensions to the CTC procedure that may provide addi-
tool to enhance the integration of new learning into practice is still tional benefit include conducting surveys of post-course behav-
under study, the current evidence is promising. The incorpora- iors to assess compliance with the CTCs, encouraging reports to
tion of simple reflective questions into a learning experience may colleagues or other peers regarding CTCs in order to build in addi-
itself be useful, as when the psychologists asks, “How can I use tional elements of accountability, or establishing timelines for the
this new knowledge?”, “How does this apply to my practice and to completion of CTCs. With continued utilization and examination,
what I do?”, or “What might I do differently based on what I have Commitment-to-Change procedures may join the ranks of other
learned today?” Although simple reflection itself appears to facili- processes, procedures and techniques that jointly constitute what
tate both learning and the translation of that learning into practice, has increasingly come to be recognized as the set of “Best Prac-
the express formulation of potential changes and a commitment to tices” in the field of ongoing professional education and continuing
those changes may add further value (Lowe et al., 2009). Overall, professional competence.
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