04.12.2023 14.24 study.ruc.

dk/class/view/32099

Subject Module Course 3: Genetics

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Semester
F2024

Subject
Subject module in Molecular Biology

Activity type
subject module course

Teaching
English
language

Registration
Tilmelding sker via stads selvbetjening indenfor
annonceret tilmeldingsperiode, som du kan se på
Studieadministrationens hjemmeside

Når du tilmelder dig kurset, skal du være opmærksom på,

om der er sammenfald i tidspunktet for kursusafholdelse
og eksamen med andre kurser, du har valgt.
Uddannelsesplanlægningen tager udgangspunkt i, at
det er muligt at gennemføre et anbefalet studieforløb
uden overlap. Men omkring valgfrie elementer og
studieplaner som går ud over de anbefalede
studieforløb, kan der forekomme overlap, alt efter hvilke
kurser du vælger.

Registration is happing through stads

selvbetjeningwithin the announced registration period,
as you can see on the Studyadministration homepage.

When registering for courses, please be aware of the

potential conflicts between courses or exam dates on
courses. The planning of course activities at Roskilde
University is based on the recommended study programs
which do not overlap. However, if you choose optional
courses and/or study plans that goes beyond the
recommended study programs, an overlap of lectures or
exam dates may occur depending on which courses you
choose.

Detailed
This course in runs in Block B
description of
content The course focus is on application of classical and
molecular genetic concepts and methods in modern
genetic analysis. The contents include 1) DNA
metabolism such as replication, mutagenesis, repair and
general and site specific recombination, DNA
transposition 2) classical genetic crosses in both pro-
and eukaryotic model organisms including viruses, 3)
genetic analysis of gene regulation, 4) gene technology,
DNA sequencing, genomics and bioinformatics.

Expected work
Estimate of the work load:
effort (ECTS-
declaration) Exam 3 hrs
Question time 2 hrs
Lectures 26 hrs
Theoretical exercises 13 hrs
Preparation 91 hrs
Total 135 hrs

Course
Text books:
material and
Reading list A.J. Griffiths, J. Doebley, C. Peichel & DA Wassarman:
Introduction to genetic analysis 12th ed. 2020

OR

A.J. Griffiths, S.R. Wessler, S.B. Carroll and J. Doebley:

Introduction to genetic analysis 11th ed. 2015

Additional reading for repetition:

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04.12.2023 14.24 study.ruc.dk/class/view/32099
Michael M. Cox, Michael O'Donnell & Jennifer Doudna, "Molecular Biology - Principles and Practice",
2'nd edition, 2015

Lecture Plan and Lecture Notes will be posted at Moodle before the start of the course.

Evaluation-
All courses include formative evaluation during the course based on dialogue between the students
and feedback
and the teacher(s). All courses are also evaluated through a questionnaire in SurveyXact and oral
forms
evaluation at the end of the course. The Study Board will handle all evaluations along with any
comments from the course responsible teacher.

Administration
INM Registration & Exams (inm-exams@ruc.dk)
of exams

Responsible
Karen Angeliki Krogfelt (karenak@ruc.dk)
for the activity

Type of
Amendment to the form of examination:
examination
For the first part of the examination the student must bring their own computer, as the exam will be
online.

During the first part of the examination the student must use their own computer to access, answer
and hand in/upload the exam, but students are not allowed to use the internet to answer the questions
given in the exam.

ECTS
5

Learning
outcomes and Knowledge and understanding of fundamental genetic terms, concepts, theories, mechanisms
assessment and methods
criteria
Knowledge and understanding of the mechanisms of replication, mutagenesis, recombination
and DNA repair in living cells

Knowledge and understanding of the principles of common methods of genetic engineering

and their applications
Knowledge and understanding of the principles of selected methods and analyses for
characterisation of genomes (genomics).
Proficiency in analysing, processing and interpreting data from genetic experiments
Proficiency in mapping genes based on data from simple classic mapping experiments
Proficiency in mapping and analysing genes based on data from molecular genetic
experiments
Proficiency in deducing simple gene regulatory mechanisms from genetic and molecular
biological data
Proficiency in presenting/communicating genetic knowledge in a precise and professionally
competent manner, with the correct use of genetic terms and concept
Competence to carry out theoretical and experimental project work on the basis of a biological
research question, using the theories and methods of genetics
Competence to solve simple practical and experimental problems of a genetic nature.

Overall
A theoretical course aimed at giving the student knowledge of fundamental theories and principles of
content
general and molecular genetics in both prokaryotic and eukaryotic organisms, and to provide an
introduction to the experimental methods used in today's genetic research.

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