FMGE NEET PG INICET USMLE PLAB

One Liners to Remember

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 Biochemistry One Liners

Hartnup disease is due to defective transport of -

Tryptophan.

Hunter syndrome is due to deficiency of - Iduronate

Sulfatase.

Enzyme-deficient in Tay Sach’s disease is -

Hexosaminidase A

The earliest symptom of Tay Sach’s disease is -

Exaggerated startle response.

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 Biochemistry One Liners

Accumulation of Homogentisic acid causes Ochronosis.

The precursor of Adrenaline and Noradrenaline is -

Tyrosine.

Norepinephrine to epinephrine conversion requires enzyme

- Phenylethanolamine N methyltransferase.

Enzyme deficiency in McArdle’s disease is - Muscle

Phosphorylase Deficiency.

Galactosemia is due to the deficiency of - Galactose 1

Phosphate Uridyltransferase.
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 Biochemistry One Liners

Serotonin is also known as - 5 Hydroxy Tryptamine.

HIAA is secreted in Urine in - Carcinoid

A most sensitive method for glucose estimation is -

Glucose Oxidase Method.

Substrate level phosphorylation in the TCA cycle is in step

- Succinate thiokinase.

Lactose produced by glycolysis is used by - Cori cycle &

TCA cycle.

Number of ATP produced per turn of the TCA cycle is - 10.

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 Biochemistry One Liners

Muscle glycogen stores cannot be used to provide

glucose into the circulation because of lack of - Glucose 6

Phosphatase.

Hormone-sensitive lipase is inhibited by Insulin.

Arachidonic Acid is synthesised from - Linoleic Acid.

Fatty liver is due to the accumulation of Triglycerides.

Acetoacetate is the primary ketone body.

Niemann Pick Disease is due to deficiency of enzyme -

Sphingomyelinase.
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 Biochemistry One Liners

Alpha oxidation of fatty acids takes place - Peroxisomes.

The urea cycle is linked to Kreb’s cycle by Fumarate.

Brain utilises urea in the form of Glutamine.

Boiled cabbage or rancid butter smelling urine is seen in-

Tyrosinemia.

Source of norepinephrine is - Tyrosine

The end product of purine metabolism is - Uric Acid.

Amino acid used in Carnitine synthesis is - Lysine.

Hormone synthesised from Tyrosine is Thyroxine.

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 Biochemistry One Liners

Amino acid involved in urea synthesis is Aspartic acid.

Enzyme defect in Krabbe’s Diseases is BetaGalactosidase.

Enzyme-deficient in Hers Disease is - Liver Phosphorylase.

Folding & unfolding of DNA is done by Topoisomerases.

LDL reuptake in the liver is associated with - Apo B100 &

Apo E.

Micro RNA is gene silencing RNA.

Vitamin B12 is absorbed in - Ileum.

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 Biochemistry One Liners

Insulin secretion is associated with Zinc.

Activated Pantothenic acid found in Coenzyme A.

Absorption of iron is increased by - Vitamin C.

The site at which 1,25 hydroxylation of Vitamin D takes

place in the kidneys is Proximal convoluted tubules.

Test to diagnose Thiamine deficiency is - RBC

Transketolase.

Haemoglobin synthesis starts with - Glycine.

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 Biochemistry One Liners

Embryonic Hemoglobin is Alpha 2, epsilon 2.

The major role of 2,3 BPG in RBC is - Release of oxygen.

Hemolysis on oxidation is seen in - G6PD Deficiency.

Iron in haemoglobin binds with - Histidine

Chylomicrons core is formed by - Triglycerides &

Cholesterol.

Inheritance of Familial Hypercholesterolemia is -

Autosomal dominant.

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 Biochemistry One Liners

Principle apoprotein in Chylomicrons is Apo B 48.

Carrier of cholesterol is - LDL.

Maximum electrophoretic mobility and least LIPID content

is - HDL.

Insulin-stimulated glucose uptake is by - GLUT4.

The normal renal threshold for glucose excretion is -

180gm%.

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 Biochemistry One Liners

Rate limiting enzymes:

➔ Cholesterol synthesis - HMG CoA reductase.

➔ Ketone body synthesis - HMG CoA synthase.

➔ Krebs cycle - Isocitrate dehydrogenase.

➔ Catecholamine synthesis - Tyrosine hydroxylase.

➔ Glycolysis - Phosphofructokinase.

➔ Gluconeogenesis - Pyruvate carboxylase.

➔ Bile acid synthesis - 7 alpha hydroxylase.

➔ Fatty acid synthesis - Acetyl CoA carboxylase.

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 Biochemistry One Liners

Disclaimer:

This information is not intended as a substitute for

professional medical advice, emergency treatment or

formal first-aid training. Don't use this information to

diagnose or develop a treatment plan for a health problem

or disease without consulting a qualified health care

provider. If you're in a life-threatening or emergency

medical situation, seek medical assistance immediately.

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