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  • Tema 1-Blood Physiology 2023

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    RIVALDO ALFREDO RIVEROS POLO
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    The document discusses blood physiology, including blood groups and distribution worldwide. It provides statistics on blood donation in Peru from 2019 to 2020, which increased from 9.15% to 13.5% of total units collected. The document also discusses relationships between blood groups and COVID-19 infection, noting one study found no significant associations. It outlines topics like blood composition, cells, hemostasis, and effects of COVID-19 on coagulation.

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    TEMA 1-BLOOD PHYSIOLOGY 2023

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    The document discusses blood physiology, including blood groups and distribution worldwide. It provides statistics on blood donation in Peru from 2019 to 2020, which increased from 9.15% to 13.5% of total units collected. The document also discusses relationships between blood groups and COVID-19 infection, noting one study found no significant associations. It outlines topics like blood composition, cells, hemostasis, and effects of COVID-19 on coagulation.

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    © All Rights Reserved
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    22 views94 pages

    Tema 1-Blood Physiology 2023

    Uploaded by

    RIVALDO ALFREDO RIVEROS POLO
    The document discusses blood physiology, including blood groups and distribution worldwide. It provides statistics on blood donation in Peru from 2019 to 2020, which increased from 9.15% to 13.5% of total units collected. The document also discusses relationships between blood groups and COVID-19 infection, noting one study found no significant associations. It outlines topics like blood composition, cells, hemostasis, and effects of COVID-19 on coagulation.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    of 94

    BLOOD

    PHYSIOLOGY
    L.A. Arteaga-Temoche
    PRECIO UNIDAD DE SANGRE PERU

    O POSITIVO: PEN 70 - 100


    O NEGATIVO: PEN 500 - 800
    https://diariocorreo.pe/edicion/arequipa/vampiros
    -merodean-los-hospitales-locales-546225/#:~:text
    =Precio.,un%20tipo%20raro%20y%20escaso.
    DONACION DE SANGRE PERU
    2019: 9.15% (37,677/344,909 unidades)
    2020: 13.5% (48,524/358,563 unidades)
    https://www.gob.pe/institucion/minsa/noticias/77833-donacion-voluntaria-
    de-sangre-se-incremento-y-llego-a-13-5-de-la-recaudacion-total-durante-2
    019

    https://www.who.int/es/news-room/fact-sheets/detail/blood-safety-and-av
    ailability
    BLOOD GROUPS WORLD DISTRIBUTION
    https://www.statista.com/statistics/1203831/blood-type-distribution-us-by-ethnicity/
    https://en.wikipedia.org/wiki/Blood_type_distribution_by_country
    https://commons.wikimedia.org/wiki/File:Map_of_blood_group_a.gif#/media/File:M
    ap_of_blood_group_a.gif
    https://commons.wikimedia.org/wiki/File:Map_of_blood_group_b.gif#/media/File:M
    ap_of_blood_group_b.gif
    https://commons.wikimedia.org/wiki/File:Map_of_blood_group_o.gif#/media/File:M
    ap_of_blood_group_o.gif
    COVID 19 AND ABO GROUPS
    https://pubmed.ncbi.nlm.nih.gov/33578447/
    OUTLINE
    BLOOD
    ❏ COMPOSING AND PROPERTIES
    ❏ CELLS
    ❏ HEMOPOIETIC PROCESS AND
    E|NVIRONMENT
    ❏ ERYTHROCYTE PHYSIOLOGY
    ❏ PLATELET PHY|SIOLOGY
    ❏ HEMOSTASIS
    ❏ PLATELET PHYSIOLOGICAL
    CHARACTERISTICS
    ❏ BLOOD COAGULATION
    ❏ FIBRINOLYSIS
    CD38
    NAD
    METABOLISM

    EXTRACELLULAR
    NUCLEOTIDES
    AVAILABILITY
    AND
    HOMEOSTASIS

    INTRACELULAR
    CALCIUM
    HOMEOSTASIS
    HEMOSTASIA
    NUTRITION AND COAGULATION FACTORS
    SNAKE HEMOTOXIC VENOM
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484289/
    COVID 19 AND COAGULATION
    https://journals.sagepub.com/doi/full/10.1177/20503121211002996

    ● As COVID-19 binds to its receptors, ACE2 expression is decreased


    leading to activation of the renin-angiotensin system (RAS),
    promoting platelet adhesion and aggregation.
    ● Attachment can also cause direct endothelial dysfunction
    promoting the formation of a platelet plug.
    ● The accumulation of angiotensin II can result in the production of
    reactive oxygen species (ROS) leading to oxidation of beta 2
    glycoprotein 1 (β2GP1), which depletes non-oxidized β2GP1 from
    binding Von Willebrand Factor, leading to a cascade of platelet
    adhesion, activation, and aggregation

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