Development And Characterization Of Surface Modified Chitosan

Nanoparticles for Selective Targeting of Lamivudine to Hepatocytes

A
Major Project Submitted To
Rajiv Gandhi Proudyogiki Vishwavidhyalaya Bhopal,
Submitted in Partial Fulfillment for the Degree of
MASTER OF PHARMACY
IN PHARMACEUTICS

Submitted by
Shivangi Yadav
Supervisor
DR. ASHISH KUMAR JAIN
M.PHARM,Ph.D

ADINA INSTITUTE OF PHARMACEUTICAL SCIENCES,

SAGAR (M.P.)
Roll No. : 0603PY14MP32Enroll.No:0603PY14MP32
2016 -2017
 ADINA INSTITUTE OF PHARMACEUTICAL SCIENCES,SAGAR
Rajiv Gandhi Proudyogiki Vishwavidhyalaya Bhopal
2016-2017

DR. ASHISH KUMAR JAIN

M.PHARM, Ph.D.

Department Of Pharmaceutics
Adina Institute Of Pharmaceutical Sciences,
Bhopal Road, Sagar-470002

------------------------- CERTIFICATE -------------------------

This is to certify that investigations described in this thesis
entitled,`` Development And Characterization Of Surface Modified
Chitosan Nanoparticles for Selective Targeting of Lamivudine to
Hepatocytes`` is being carried out by Miss Shivangi Yadav in the
laboratories of the Adina Institute Of Pharmaceutical Sciences, sagar,
under my supervision and guidance, in partial fulfillment of the
requirements for the degree of Master Of Pharmacy in
Pharmaceutics in the faculty of Medicine, Rajiv Gandhi
Proudyogiki Vishwavidhyalaya Bhopal.

The thesis is now ready for examination.

Place: Sagar Dr. Ashish Kumar Jain

Date:
 `
ADINA INSTITUTE OF PHARMACEUTICAL SCIENCES,SAGAR
Rajiv Gandhi Proudyogiki Vishwavidhyalaya Bhopal
2016-2017

------------------------- DECLARATION-------------------------

I hereby declared that this dissertation entitled ,`` Development

And Characterization Of Surface Modified Chitosan Nanoparticles
for Selective Targeting of Lamivudine to Hepatocytes `` is a bobafide
and genuine research work carried out by me in the laboratories of
Adina Institute Of Pharmaceutical Sciences, Sagar under the
guidance of Dr. Ashish Kumar Jain Professor, M.Pharm. Ph.D,
Department Of Pharmaceutics.

This dissertation is now ready for examination .

Place: Sagar Miss Shivangi Yadav

Date:
 ADINA INSTITUTE OF PHARMACEUTICAL SCIENCES,SAGAR
Rajiv Gandhi Proudyogiki Vishwavidhyalaya Bhopal
2016-2017

------------ ENDORSEMENT BY THE HOD OF INSTITUTE------------

This Is to certify that the dissertation entitled, `` Development And

Characterization Of Surface Modified Chitosan Nanoparticles for
Selective Targeting of Lamivudine to Hepatocytes `` is a bonafide
research work done by Miss Shivangi Yadav under the guidance of Dr. Ashish
Kumar Jain Professor, M.Pharm. Ph.D, Department of Pharmaceutics, Adina
Institute Of Pharmaceutical Sciences, Sagar M.P.

Place: Sagar Director

Date: Dr. Sunil Kumar Jain

M.Pharm., Ph.D