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Horner Syndrome
BY JORGE MUNIZ, PA-C

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Horner syndrome results from disruption of the sympathetic pathway that runs from the
 hypothalamus to the eye. Classic signs include miosis, ptosis, and anhidrosis of the a!ected
side.

Causes include brain tumor, brain stem infarct, pancoast tumor, cervical adenopathy, skull
and neck trauma, carotid dissection, and thoracic aortic aneurysm.

Instilling cocaine or apraclonidine drops into both eyes can con"rm the diagnosis of Horner
syndrome. Imaging studies such as MRI, CT, or MRA may be obtained based on the history
and physical exam. Treatment depends on the underlying cause of Horner syndrome.

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