Professional Documents
Culture Documents
to help
build
strong
bones
Thursday 2nd Nov 2023 Available from Symbion, Sigma, API & CH2
Always read the label and follow the directions for use.
Today’s issue of PD
Pharmacy Daily today
Countdown to APP2024 has started
features three pages of The curtain raiser to the largest rescue diver and anaesthetist,
news, including our Beauty & pharmacy event in the Southern Dr Richard “Harry” Harris and
Hemisphere has started, with the history-making humanitarian, Rabia
Wellness feature, plus a full
official program now available Siddique,” he remarked.
page from BioCeuticals and the
for the Australian Pharmacy With the 8CPA negotiations
November MIMS Update.
Professional Conference and Trade planned to be concluded close to
Exhibition (APP2024), HERE. APP in Mar 2024, “this is one year
Delegates can also network with you must attend,” urged Sclavos.
APC focus group 450 exhibitors and suppliers at the APP2024 features pre-conference
The Australian Pharmacy trade exhibition which will be held workshops on Wed 13 Mar.
Council (APC) is again inviting on the Gold Coast from 14-17 Mar. minimisation, and an Early Career APP2024 also offers delegates
preceptors and supervising Past Pharmacy Guild President Pharmacist stream”. an exciting networking and social
pharmacists to provide feedback and conference convenor Kos “The Opening Plenary will program including a ‘Glowchella’
on the Intern workplace-based Sclavos (pictured) said the program showcase and recognise awards of themed Street Party, the ever-
assessment tools via a virtual reflects the conference theme, excellence including The Pharmacy popular Welcome Reception, a
focus group discussion. ‘Navigating the future together’, of the Year Award, the MIMS/ Women’s Networking Lunch and
The final focus group will be and will focus on the profession Guild Intern of the Year and the a Pharmacy Assistant Networking
held on Mon 20 Nov 7:30pm heading towards 8CPA. Pharmacy Guild of Australia/ Lunch with the 2023 Pharmacy
to 8:30pm AEDT (Sydney/ APP last year saw a record 6,000 Maxigesic Pharmacy Assistant of Assistant of the Year, Colby Diek. JG
Canberra/Melbourne time). plus attendees (PD 24 Mar), and the Year,” Sclavos explained.
To receive the Zoom details Sclavos said what makes APP “The Alan Russell Oration on Thu
CLICK HERE. unique is that it “offers a range afternoon will provide an update
Future together
Pharmacists can find out of education streams to cover all on where we are at with 8CPA and Bioceuticals has been
about the workplace-based aspects of community pharmacy Fri morning’s State of the Industry supporting professionals for
research project HERE, or to including business, innovation Panel is always a highlight. over 30 years with evidence-
email APC for more information and leadership, clinical pharmacy/ “I also look forward to hearing based products, on-call sales
CLICK HERE. product updates, rural pharmacy, from our keynote speakers, 2019 support, education and training.
cultural engagement, harm Australian of the Year, Thai cave See more on page four.
Andusomeran (Spikevax XBB.1.5) is formulated in lipid particles, which enable delivery of the nucleoside-modified mRNA into
host cells to allow expression of the SARS-CoV-2 S antigen. The vaccine elicits an immune response to the S antigen, which
protects against COVID-19. Spikevax XBB.1.5 is indicated for active immunisation to prevent COVID-19 in individuals 12 years of
age and older in accordance with official recommendations. Spikevax XBB 1.5 is contraindicated in individuals with known severe
allergic reactions (e.g., anaphylaxis) to a previous dose of Spikevax (original), Spikevax Bivalent Original/Omicron (BA.1),
Spikevax Bivalent Original/Omicron BA.4-5. Spikevax XBB.1.5 suspension for injection contains andusomeran 50 mcg per 0.5 mL
dose and is available in packs of 10 single-dose vials or prefilled syringes.
Mavacamten (Camzyos) is a selective, allosteric, and reversible cardiac myosin inhibitor. Mavacamten modulates the number of
myosin heads that can enter power-generating states, thus reducing, (or in hypertrophic cardiomyopathy (HCM) normalizing), the
probability of force-producing systolic and residual diastolic crossbridge formation. Mavacamten also shifts the overall myosin
population towards an energy sparing, but recruitable, super-relaxed state. Excess cross-bridge formation and dysregulation of the
super-relaxed state of myosin are mechanistic hallmarks of HCM, which can result in hypercontractility, impaired relaxation,
excess energy consumption, and myocardial wall stress. In HCM patients, myosin inhibition with mavacamten normalizes
contractility, reduces dynamic LV outflow tract obstruction, and improves cardiac filling pressures and biomarkers of cardiac stress,
improving symptoms and exercise capacity. Camzyos is indicated for the treatment of adults with symptomatic NYHA class II-III
obstructive HCM. Camzyos is contraindicated in concomitant use with moderate to strong CYP2C19 inhibitors and inducers,
strong CYP3A4 inhibitors, and moderate to strong CYP3A4 inducers. Camyzos capsules contain mavacamten 2.5 mg or 5 mg and
are available in packs of 28.
Rimegepant (Nurtec ODT) binds with high affinity to the human calcitonin gene-related peptide (CGRP) receptor and antagonises
CGRP receptor function. Multiple lines of clinical evidence point to a role for CGRP in migraine pathophysiology: 1) serum levels of
CGRP are elevated during migraine; 2) treatment with anti-migraine drugs returns CGRP levels to normal coincident with pain
relief and 3) intravenous CGRP infusion produces lasting pain in non-migraineurs and migraineurs. Nurtec ODT is indicated for
acute treatment of migraine with or without aura in adults and as prophylactic treatment of episodic migraine in adults who have at
least 4 migraine attacks per month. Nurtec ODT orally disintegrating tablets contain rimegepant 75 mg and are available in packs
of 2, 4, 8 or 16.
New Presentation
Progesterone (Prolutex) is now available as a solution for injection. It is indicated in adults for luteal support as part of an
Assisted Reproductive Technology treatment program in women who are unable to use or tolerate vaginal preparations, or where
there is a need or preference to use an injectable form of progesterone. Prolutex is contraindicated in undiagnosed vaginal
bleeding; known missed abortion or ectopic pregnancy; severe hepatic dysfunction or disease; known or suspected breast or
genital tract cancer; active arterial or venous thromboembolism or severe thrombophlebitis, or a history of these events; porphyria;
and in individuals with a history of idiopathic jaundice, severe pruritus or pemphigoid gestationis during pregnancy. Prolutex
contains progesterone 25 mg per 1.112 mL vial and is available in packs of 7.
New Indications
Ivosidenib (Tibsovo) is now indicated for the treatment of acute myeloid leukaemia (AML) that carries an IDH1 R132 mutation as
monotherapy, or in combination with azacitidine, in newly diagnosed patients who are not eligible to receive intensive induction
chemotherapy; or as monotherapy in patients whose AML is relapsed and/or refractory to prior therapy.
Secukinumab (Cosentyx) is now indicated for the treatment of active moderate to severe hidradenitis suppurativa (acne inversa)
in adult patients with an inadequate response to conventional systemic hidradenitis suppurativa therapy.
New Contraindications
Midodrine HCl (Vasodrine) is now contraindicated in obliterative blood vessel disease of any severity, acute nephritis,
hypertrophy of the prostate gland with residual urine volume increased, and vasovagal hypotension.
This list is a summary of only some of the changes that have occurred over the last month.
Before prescribing, always refer to the full product information.
Copyright © MIMS Australia Pty Ltd, PO Box Q1899, Queen Victoria Building, Sydney NSW 1230
T +61 2 9902 7700 F +61 2 9902 7771
www.mims.com.au
ACN 050 695 157, ABN 68 050 695 157