ISLAMIC INTERNATIONAL DENTAL COLLEGE ISLAMALAD Pharmacology Test 2™ year BDS 2023 Date: MCQs: 30 Marks _| Answees r Roll Noy Time: 30min 1. AGO-yearold male presents veith a severe dental infection and on abscess in his lower jaw. He reports pain, swelling, and difficulty in opening bis mouth. Which medication bk Commonly prev nhed ta ever anaerobic bacteria in this situation? a) Cephalexin b) Erythromycin ¢) Metronidazole 4) Penicitlin V 2. Ahmad is taking a sulfonamide drug to treat a bactenal infection Ke experiences rash, fever, and joint pains few days after starting the medication. What is the most likely explanation for these symptoms? a) Allergic reaction to the drug b) Bacterial resistance to the drug. ¢) Drug interactions with other drug d) Normal side effects of the drug. 3. To get the synergistic effect all the f-lactam antibiotics can be combined with a) Aminoglycosides b) Chloramphenicol c) Macrolides d) Tetracycline 4. Sarah, a 30-year-old woman, is diagnosed with a urinary tract infecuon Physician prescribes her a sulfonamide medication to treat the infectionT hich of the following is the primary mechanism of action of sulfonamides Scanned with CamScanner8) Inhibition of bacterial cell wall synthesis 1b) tnhibition of bacterial DNA gyrase €) Inhibition of bacterial cell membrane synthesis a) Inhibition of folic ackd synthesis $ Genetic difference in hepatic N-Acety ation must be considered when starting, Weatrnent so Hine aoti-TH dewgs specifically for which dev a) Axpirin b) Ethambutot ©) Isoniazid a) Pyrazinamide erste Ibie drug interactions. Al i ions preven OTT absorption of which of tha following drug a) Cephalexin b)_ Erythromycin ¢) Penicillin G d) Tetracycline 7. A 40-year-old patient with active tuberculosis is being prescribed a standurd firsteline regimen. After few weeks, patient develops severe joint pain and redness. Which drug is ment likely responsible for this adverse reaction’? a) Ethambutol b) Isoniazid ¢) Pyrazinamide 4) Rifampin 8. A group of travelers are planning a trip to a region known for its high prevalence of cholera. To reduce the risk of acquiring cholera, they decide to take a prophylactic antibiotic. Which of the following fluoroquinolone is a recommended choice for cholera prophylaxis? 2) Ciprofloxacin b) Erythromycin ¢) Moxifloxacin d) Norfloxacin 9. Sarah, a 32-year-old woman, presents to the emergency department with symptoms of urinary tract infection. The urine culture reveals the presence of Escherichia coli, end the pati is being prescribed antibiotics. Which of the following drug is the most appropriate choice her urinary tract infection? Scanned with CamScannerfo tena. ay Amiprciltin b) Ciproflonscin ©) Doaseyehine @) Trimethoprn 11 A 25 year afd gurl came to het doctor with complain of pemphes Oe het fae Des her an anumicrobial drug which acts by inhibiting protern syntbers. afier taking Shue eee she started feeling dizziness, nausea and Vomiting must probably the drwy wy! a) Amonteittin by Chindamysin ©) Doxyeyeline dy Enythromycin, 12. Clanthromyein and erythromycin have very simular ypectra of anime robe! a major advantage of clarithromycin is that it 4) Eratieates mycoplayma infections in a single dose by Does not inhibit hepatic drug-metabolizing enzymes 6) Has greater activity against H pylon J) Is active against methicillin-resistant strains of staphylosoxcy cane an on 13. A 25-year. man prevents with a shan infection. and Une culture te ou) caused by beta-lactamase-producing bacteria Which penicillin-hased & most appropriate choice for this infection * baie would he the a) Augmentin by Mezloe ©) Nafeillin d) Penicillin V in ant strains of 14, The drug that is most hhely to be effective against multidrug tes Micohacterium tuberculosts, including those reuistant 10 even streplomyein a) Amikacin b) Clanthromy cin ) Gentamicin d) Meropenem 15. A researcher ts conducting an experiment to determine the mode of action of « new synthesized annibiotic He observes that the dinug interferes with the formation of pepruke hee between amine acids during protein synthesis: Which part of the hacterial pihsaome Likely targeted by this antibiotic? Scanned with CamScanner8) RNA ‘ by URNA ©) tars sts After few days the drug 1s s could be cot in presen a s severe mus te weal er unvesti Which class of antibiot ¢ with the spomuble for thes ade effect” a) Amunoglycos ) 4) Tetracyclines 17. A paticnt presents with a persistent infection caused by a bacterium that has developed resistance to multiple antibiotics. The doctor decides to use a combination therapy involving two protein synthesis inhibitors with different mechanisms of action Which of the following drug combinations would be the best choice for this paticat? a) Anthromycin + Streptomycin by Clindamyein + Linezolid ¢) Exythromycin + Gentamicin d) Tetracyeline + Vancomycin 18. A 32-year-old man, presents to the emergency room with symptoms of a severe skin infection. The doctor suspects a bacterial infection and decides to prescribe an antibiotic. Given the patient's medical history of mild penicillin allergy, which beta-lactam drug would be the most appropriate choice? a) Azithromycin b) Cephalexin 6) Erythromycin ¢) Vancomycin 19. A 45-year-old woman is diagnosed with acute otitis media. The doctor decides to prescribe a beta-lactam drug to treat the infection. However, she is currently pregnant, and the physician needs to consider the safety of the drug for both mother and the foetus. Which beta-lactam drug would be the best option for Sarah? a) Augmentin b) Ceftriaxone ¢) Cloxacillin d) Meropenem Scanned with CamScannerpo AAS year yofection tha ddeag that ts legs Mi uted be thy n with a history of penicilhn allergy presents with a severe pran Hes an antibiotic treatment The physician wants to p ent Which of oly to Cause an allergic reaction tn this p. ont alternative? a) Ampiciitin b) Artreonam €) Ceftriaxone ad) Meropenem 21. ASO year-old male patient is adevit! community acquired pneu i to the hospital with a confinmed diagnosis ot nonia. The physician plans to initiate an empirical antibiotic therapy until the exact pathogen is identified. What Is the first-line beta lactam drug of choice for empirical treatment of corm nity-acquired pneumonia? a) Auamentin b) Cefepime ©) Cefotaxime: d) Cefuroxime a who has failed to respond to: resistance, the drut most likely to be effective ts 22. Ina potient with positive culture treatment with vancomyein because a) Azithromycin by Clindamyein ©) Doxyeyeline a) Linezolid 23. A435 year old woman complains of frequent urination, pain & buming sensation upon urination. She has no past history of urinary tract infection (U11), but now she ts diagnosed With UTI caused by F Coli, Which one of the following drugs would be the simplest & sate for her? a) Co-trimanazole a) Erythrosine b) Gentamyein ©) Imipenem 24. A patient is diagnosed with a severe respiratory tract infection caused by a Gram-nepative bacterium. The patient is allergic to penicillin, Which of the following protem synthesis inhibitors would be a suitable altemative treatment option tor thts patient a) Azithromycin b) Clindamyein ¢) Linezolid d) Streptomycin Scanned with CamScanner2SA17 year od Dey prencess wih nghs lower guatrant pan CT waa dows appentiots ou on to operation tone for sarge What woe Wy a pant anntiene Before sexpery? cot revtal Sacto 26.0 SS year old man CO penatc doute of Garttoa with aiennul cramps sat owe yea ths laews of intertios ant ovt wel Dowding. The most appropriate dreg mht ou mont extale for this patent a) Amousilin A 60-year-old male with chivnic obstrevtive pulmonary diwaye (COPD) present exacerbation of symptoms Wine its atypical pneumonia coverage? eoregennvlone a) Ciprofiowsein D) Gemifioucin <) Levontorse! @) Moxitlonacin 8 with tubervuley 28. A 28-year-old female pation: weeks of treatment, she complains o' tubercular drug is associated with these a) Isoniazid >) Ethambuiol ©) Pyrazinamide d) Rifampin iv on a fourntrug anu-TB regimen NI er hands and fect Wh cal symptoms? 29. A $S-year-old panent with a history of cystic fibrosis presents wah symptoms cough, and greenish sputum. Suspecting a Pseudomonas aeruginosa infection. whe following antipseudomonal penicillin would be the most appropriate choice for treatment” a) Amovicillin b) Ampicillin ¢) Piperacillin d) Penicillin V Scanned with CamScannerenary tract? fect1o" wast cn“ a abdo™ — hea are abo ofuse water dar * “ a€¢ patent with aw . wh gyn fo nO a4oyeat -old ays of treatment, the patient éey eloped 9 afhicee to** x resting reveals t Clostrideum @ the most likely t sais Al he presence of o cause this pSe udomembrancu® a) Trimethopn™ b) Ciprofioxac® c) Clindamyo® d) aAmoxicitlie Scanned with CamScannerAIC INTERNATIONAL DENTAL COLLEGE AABAD ative Assessment 2ar BDS 2023 Date: 18/09/23 5: 30Marks Roll No; : 30min 1A paticnt was prescribed tab Ibuprofen 400 ing thrice daily te aelecve he pon | Answers ner tooth extraction werk later hie develops a bleeding ulcer an hes st Which drug to be prewenbed, seleetively to treat this type ef | | a Aluminium hydeanide b) Wismuth: oe Vamotidine gd) Misoprostal » What he rate of 2A 26-yearold female has taken pharmacological exeretion aspiri wiple should be followed to incres a) Avinlily the urine | by Alkalinize the urine ©) Alkalinize the plasma d)— Acidify the plasma year old woman iy berg treated to reduce the pain of Anky lose ‘ Spondylitis for Last two years. Now al hay 2 meal What is the most likely causative a) Androlone b) Clomiphene €) Prednisolone ) Vasopressin 4. A pationt taking tablet warfarin started self-medicating to relieve lis ulcer na Which drug would increase the rish of bleedin \ a) Cimetidine | bd) Misoprosto! “ { ©) Ranitidine | d) Sucralfate Scanned with CamScanner+ baht He bate ok ORT EV Feebe ed adog tar ok ee citeantin pane he gin HOF + Fore pantry Hoe vhs to ouapecty ot acannon at sn Alt ep eve ook foes gante ten Ad Harare By Cetra 1A Ferme tine AN Stowactit plans HN arate nie ato Which druy ts a full ayonist at opiend t Jaap er duration of action and fewer wathatrawab sein oni aheuptatic ot ay Hentanyt by Hydtramorphone ©) Methadone a) Nalbuphine 3 Winch of the fothnwing deag binds to mucosa of the GIT and forms a physical Baron fe He repem? a) Hismutts chloride by Lamotatine 6) Sodium Hicarhonate UW) Sucraltate 9 A paticnt with rhoumatind antntiy presents wath sore throat. good health previouvly Comptcte bloat count 1 aot likely causing thiy adverse effect" 4) Aspirin by Diclofenac ©) Indomethacin dy Phenylbutarone er and depends wale a white soll os 10 On continued use of supraphy nological plucocorticond, which of the follow me avers Cc < observed” a) Asthona by Meningitis £) latrogenic Cushions syndrome 4) Rheumatoid Arthritis Scanned with CamScanner21 Long term ute of og od Can leas to w UA peterson b) increayed aiertness ©) Opa droterance @) Weight iors ey te ate OS typeternan tH derrg hm 22: ASS year od rae patert cretents aed levels ave clevated and he hat a brow be the mat? aporonriate chonce tor treating * ip Tremere 8) Cokmore ch indometsace @) Properend fotomens Ora a 22 AAS year old tema patent wth Med cater Pow Be aoees HS 2) Atopurec’ DB} Cokmere €) Proverecd @) Nepronen 24 ABD yearcld male pines wth wvewsw the following mescatons thowd be 4) < b) Colcheine ©) Probereed 2) Febusostat 25 AAD year ols male patent etcom time ote a) Alloguneo! ) Cocnane ©) Probesers 6} Feburostat 26 Apationt with severe post-operative pain ss pres Des at Oped arageac to Tat¥ET he discomfort. Which opie receptor 15 premaniy responssie for the analgesc eects of a) Delta receptor b) Kappa receptor <) Mureceptor Scanned with CamScannerV paticatt tibes a thug thet has analy oy pveabally fatal beiwetonn ty abe barge jctaotis prationts Wie dive is ot fits ow tes tlre we tb there Which opiond analgese is assocuted with a tegher rat of ream atony rates ML cotene b) Fentary hb Onycodane @) Tramacot § tetead of depres a) howe < AT fb tanger Weutphal » eb bemperaer Ay Vasmotet vsiter 14 What s a potential cardiovascular adverse effect associated with the use of CO? inhibitors? 8) Bradycardsa b) Mypotenson A increaved nv of stroke 6) Palptations [SA premature eyanosed new-born is found to have a heart murmur 07) Dopp! indocates the presence of a patent duct’s arteriosus A drug is presenbod, and du follow up exam, the murmur ts gone. A new eehocanhogram imaticates a norma’ How inside the heart. The drug presenbed was mowt likely a) Aspirin Unstornethscats Ne) Montelukast ) Propranolot Scanned with CamScanner1604 20-yearold patient experienced beonchos allergy. Which one of the following d leukotriene ov crproduction”? yn and shortness of hreathy dow to anperm gs wll empeenve this coanditune yy lock 4) Uydnconisone fy Ibuprofen 6) Dirednisrne Aatitlubast 17 In an emergency department. a pustient with severe pain duc to fractured saw reco ed big merphtine, He subsequcatly developed a severe reaction characteriza by ppinporet pupil 6 depression, and coma. Which drug is most bikcly to he wed as an antidote for this ever chnare of rmcephine? ab tentaayt VF Nalhupiins fe} Naioxwos Al) Nattiresone 18. Ina comatose patient suspected of pooaning. which of the following findings would be against the drug being morphine ' a) Deep coma by Hypotension VT Medan dy Rexpiratory deprersion 19. Proton pump inhibitory are most eflective when they are given wh Nice meats by Before meats ©) Along with sucralfate A) During protong fasting 20. Which antacid causes diarthea asa side effect invicad of constipation a Jaminum hydrowde by) Calcium bicarbonate ) Calcium chloride dd) Magnesiam hydroxide Scanned with CamScanner~ @) Sgma receptor 27 Armad 1 aller 19 aspen and wants to manage bes dental pan Wiech of thee following anor would be a saler alternative tor hen? 4) Deciotenas b) Ketamine ©) Morphine dy Tramadot 28 Somwa has a tamuly hatory of heart disease ant wants to start a dady meteaton to TraUce the ye of abeart attack Which of the folloanng sa Common ute of axprin? 2} lowerng, blood pressure 1b) Preventing blood elot farmation 6 Reducing inflammation 1 ahernes d) Treating bactenal mtections 27 AA year old patient with rheumatow artenta Nay bres on a hegh dave of oral Cortcostetinds tow the past sia months Lately, the patient has been comptaning of mereawed thuret, Hequent Urination. ant weight gan Which of the following adverse etfecty of cortcarterods 6 mont Bhehy resmenwnie toy theve symptoms? ay ») ” 4) 20. Akbar, a case of known peptic ulcer disease ts being prosenbed a triple therapy Hepylon Which cont a Gane acer Hype Nypert yea Oxteoparows ter et aude ate mation of drugs ts commonly used in this omen? Amonreilin metronidazele & Omeprazole by Caletum carbonate, Crmetuline A Alpsnate cc) Omeprasole, Ranitidine & Sucralfate d) Prrenzipin. Hismath chloride & famotidine Scanned with CamScannersLAMIC INTERNATIONAL DENTAL COLLEGE LAMABAD opic (ANS, Antihypertensive, Diuretics, Anti anginal drugs and Sveletal muscle relaxants ) jarmacology Test * year BDS 2023 CQs: 30 Marks Date.27/10/24 me: 30min : ai > Answers name: FAWMA Rating, AYO tension, 1. A 68-year-old woman with a history of bi at ~~ diabetes. and chronic kidney disease. visits her doctor for 2 ~~ regular check-up, Her blood pressure is 160/95 mmif Which of the following antihypertensive drugs would * the most suitable for her condition? = — a) Beta-blocker | b) Calcium channel blocker aa ¢) (ACE) inhibitor t =—— d) Diuretic causes cyclospasm rather than Tt 2. Which one of the followir } cycloplegia when used topically in the eye a) Atropine b) Cyclopentolate ©) Physostigmine d) Prazosin 3. A §0-year-old woman with heart failure pres Worsening shortness of breath and peripheral edema. The physician decides to start a loop diuretic to relieve her symptoms Which of the following is a common side effect associated with , loop diuretics? a) Hyperkalemia b) Hypotension c) Olotoxicity dy) Bradycardia e@ Scanned with CamScanneray Nibw by Die ot Al) Noradtrer W Saima a Weyear amy Which at ine hypertension during her renctally consed ad ACE intibnors b) Beta-blockers ©) Diureties a) Methy tops sna and hypertension Her doctor nd cardiac output. Which class. gto” a) ACE inhibitors by Beta-blockers ©) Diuretics dy Catenm © ancl blockers 12 Low doses aline dilate the follow vascular bed a) Cutaneous by Comeal 6) Mucosal d) Shel tisele A patient underwent bowel surgery duc to intestinal obstruction, Next day, during ward rounds, the staff nurse tells that he 1s unable to pass the urine after removing the urinary catheter. Which of the following drug will you advise him to solve this issue? a) Atropine b) Bethanecol ¢) Oxybutynin d) Prazosin Scanned with CamScannertaining. ve ofurmne and . iy watenng from nose and " Nene ‘ shal he ' w f a) Bella by Barbrturate ©) Be Zep dy Ant § J drophoni 5 str ne cardiac farlure that blocks both alpha & beta rs Wath sure funnel Blocking acti ty as well ty” a) Betarolol by Carvediolol ©) Labetaiot d) Timolol SS glaugoma ject the diuretic that 1s most effective in acuie a) Indapamide b) Amilonde ©) Mannitol d) Furosemide Scanned with CamScannermuscle relaxant during surgery t develops shin rash when exposed of the following drug would be responsih Atracunum by) Gall amine ©) Tubs dd) Pancuronum ne 20. A6S year ok! male presents with complaint of difficulty in urination and post Noa! dribbling for Last 3 months On digital rectal eyarmination, his prostate appears to be enlarged but smooth ity Which of the following drugs can be t > Soocs not have any teve the nus a) Prazosin b) Propranolol ©) Ritrodrine 4) Tamsutosin 21 A 70-year-old man with a history of gout is prescribed a diuretic for his hypertension. The physician opts for a diuretic that minimizes the risk of exacerbating his gout symptoms. Which diuretic is the best choice for this patient? a) Hydrochlorathias b) Furosemide: ©) Chlorthalidone @) Metolazone 22. A house officer considers presenting of the following preesisting conditions wo the dru; Propranolol for a $3 year old patient. Which wild most likely contraindicate safe use of 4) Angina Pectoris b) Bronchial Asthma ¢) Essential I d) Mild Heart 23. A person is hit by a car and is taken to emergency in semi-conscious state, His blood pressure is 80.60 mmlly. pulse 100 min. The doctor administers intravenous fluids to stabilize the patient. [he pulse & BP improves but urine outpat is still very low, Which of the following drugs can be given in the setting to improve the urine output? Scanned with CamScanner% apaticat During the apply vasoconstes smost sustable fer 14 Dr Nawal is supposed to extract upper 2" molar to Procedure, profuse bleeding started suddenly Now on the wound to stop the bleeding Which of the fo! this purpose? a) Albuterol b) Dopamine c) Epinephrine 4) Propranolol 1S. The drug wed tot cardingenie shock. which acts only on beta-! receptors is? 1 the patient a) Albuterol b) Dobutamine 6) Epinephrine d) Isoproterenol omist of accty Iehe At which place it cannot 16. Atropine ts a competitive antsy block the actions of acetyleholine? a) Bronchuy b) Constrictor musele of iris ©) SA node of heart d) Skeletal musele 17. A S$-year-old patient with severe post hepatitis ts ts being started on a diuretic for another condition Two: days later he 1s found in coma. Which of the following drug ts most likely to cause coma in a patient wath ettrhosis? a) Acetarolamide b) Amiloride ¢) Furosemide d) Hydrochlorothiaside 18. All of the following drugs can be used to glaucoma. Which one reduces intraocular pressuc aqueous humor? ¢ treatment of wide-angle ‘ccrcasing the formation of the a) Echothiophate b) Pilocarpine ¢) Physostigmine d) Timotol Scanned with CamScannera) Diurettes b) Dobutamine ©) Dopamine J) Epinephnin likely taking? a) Albutero! b) Ipratrop 6) Ovym dy Pilocarpine 25 A patient with cirthoss a) Hydrochlorothiaznte bp Furosernd ) Spironolactone d) Butamde 26 Ina roadside accident. a patie: department. Whuch one of the {c use in carly surgical manage a) Atracunium b) Pancuronnum ¢) Rocuronium d) Tubocurarine 27. Indicate an alpha-receptor antagonist. which binds coval causing irreversible blockade of long duration (14-48 hours o ty to alpha meeptess. a) Phentolamine b) Phenoxybenzamine c) Ergotamine d) Prazosin Scanned with CamScannerhistory of myocardial infarction. experiences 28. Musa, a SR-year-old mar with a 2 antianginal drugs would be the most angina at rest. Which of the follow appropriate immediate treatment to relicve his symptoms? a) Nitroglycerin b) Propranolol ¢) Diltiazem d) Clopide 29. A40y myocardia’ icy due to post a (Prinzmetal's angina drugs is most b) Beta c) Or d) ACE inhib nic Scanned with CamScanner