Professional Documents
Culture Documents
Original Research
Comparison of prescribing and dispensing
processes between veterinarians and
pharmacists in New Zealand: Are there
opportunities for cooperation?
Arlene McDOWELL, Lauren ASSINK, Rebecca MUSGRAVE, Hannah SOPER,
Chantal WILLIAMS, Pauline NORRIS.
Received (first version): 24-Aug-2010 Accepted: 29-Dec-2010
Table 1. Questions asked during the interview with staff from the veterinary practices.
Records
How long are records kept?
Where are the records kept?
How are the records categorised?
Do you have a consultation recording guideline?
Can an animal’s previous consult be referred to?
Is there standard veterinary record dispensing software?
General animal/treatment
What are the majority of animals that come in? E.g dog, cat?
Is there a procedure / guideline that you follow for each consultation?
Is there a standard treatment guideline for some conditions?
Prescriptions
What is the period of supply of a veterinary prescription?
Is there a dosing nomogram for animals (mg/kg) and where does one look up that information?
Where do vets compound and dispense veterinary medicines?
Where would you find additional information about drugs, and also about specific conditions?
Do you have involvement with Pharmacists? If yes, in regards to what?
What are the most common problems with animals coming in, and seasonal variations?
What is the role of the vet nurse with regard to the animal care, including prescribing and dispensing?
Antibiotics
What proportion of consultations results in an antibiotic prescription?
What is the most common antibiotic given and what is its dose and formulation?
Drug supply
Where do you buy medicines?
Do drug sales representatives visit you?
How do you decide what to buy and how much to buy?
Who decides what is purchased?
Table 2. Class, indication for use and dose range of antimicrobials frequently prescribed and dispensed by veterinarians in the
Dunedin region.
Drug Class Form Use Dose
Tetracyclines Doxycyline Often used on cats for an Dogs: by mouth 10 mg/kg daily, given with
abscess and respiratory food
infections Cats: 10 mg/kg daily
Quinolones Enrofloxacin Used in animals not Dogs and cats: by mouth 5 mg/kg once daily
responding to other antibiotics or in divided doses twice daily
and hard to treat infections/ Subcutaneous injection: 5 mg/kg daily
deep tissue infections
Cephalosporins Cefalexin Very commonly used for skin Dogs and cats: by mouth 10-25 mg/kg twice
infections and UTIs daily, or subcutaneous or intramuscular
injection 10 mg/kg once daily
Penicillins Amoxycillin and Commonly used for abscesses Dogs and cats: by mouth 10-20 mg/kg twice
Clavulanic acid daily, by subcutaneous injection 7 mg/kg once
daily
Sulphonamides Trimethoprim in Occasionally used for general Dogs and cats: 30 mg/kg per day per oral or
combination with purpose, bladder, soft tissue subcutaneous injection
sulfadiazine infections
animals, veterinary software was often more by veterinarians. However, when veterinarians
complex than pharmacy dispensing software, prescribe medicines to be dispensed by
because it includes medical history as well pharmacists, there is legislation regarding the
prescribing history. Like pharmacy dispensing period of supply. This is due to a legal difference
software, veterinary programs allow for the between an “authorization” and a “prescription” of a
construction of labels for medication. Unlike veterinary medicine. When veterinarians, or their
pharmacy dispensing software, veterinary programs staff, dispense medicines this is referred to as an
included fewer features like interaction prompting authorization (a documented instruction authorizing
and essential medical information. The prescribing the sale or use of a medicine by a veterinarian
veterinarian must also keep records of each (Agricultural Compounds and Veterinary Medicines
prescription issued for five years and these should (ACVM) Standards for Prescription Animal
be cross-referenced to the details of the associated Remedies, Section 2.4.3). A prescription refers to a
veterinary consultation (ACVM Standard for documented instruction to dispense a medication
Prescription Animal Remedy Veterinary Medicines, and is usually intended for pharmacists or traders.
Section 2.4.3). This is in contrast to a pharmacy In the latter case, the medicine must be dispensed
where prescriptions must be stored for 10 years, on within 30 days of the date of writing and the
site for three years in original form and then for a prescription must specify a period of treatment, not
further seven years to comply with legal standards exceeding six months (ACVM) Standards for
(Health (Retention of Health Information) Prescription Animal Remedies, Section 2.4.3). Thus
Regulations SR1996/343). In both veterinary clinics there are more strict requirements for medicines
and pharmacies, records were kept a minimum of dispensed to animals by community pharmacists
10 years and were usually maintained for the life of compared with those dispensed by veterinarians.
the patient, this complies with Section 45 of the Medicines dispensed to human patients are further
Medicines Act 1981, which states that every person restricted by legislation. Doctors are restricted to
in a business who supplies medicine must keep prescribing a maximum of three months supply of a
records for such period as may be prescribed. medicine at any one time. Depending on the
medication prescribed and the funding
Veterinary prescribing is the process of selecting a requirements, a pharmacist may dispense the total
suitable medication and treatment regime tailored to three months supply at once, or as a monthly
the animal’s needs. Legally, medicines that are dispensing. Controlled drugs for humans have their
classified as ‘prescription only’ may only be own requirements. These can be prescribed for a
dispensed by a veterinarian or pharmacist following maximum of one months supply and dispensed in
a clinical assessment by the veterinarian and may quantities sufficient for either one week or 10 days
only be dispensed or sold in accordance with a treatment.
prescription. Although it is not common practice for
veterinarians to write prescriptions to be filled in Our study concluded that veterinarians in this region
community pharmacies, it does occur in specific themselves did the majority of the dispensing
situations. In many instances it is more economical including selection of the medicine from the supply
for the patient if the veterinarian writes a area, packaging the appropriate quantity and
prescription, as the cost of the medicine dispensed labeling the medicine before giving it to the
by pharmacies is usually lower than the cost at the animal/owner. In some instances, veterinary nurses
veterinary clinic.5 If the veterinarian is aware of would aid in the dispensing of routine medication,
financial hardship with their clients, then they may under the direction of the veterinarian. Legally an
take this into consideration and opt for this course of agent or employee at a veterinary practice may
action. While veterinarians acknowledged that it dispense a prescription medicine for the treatment
was not routine practice, they agreed that they of an animal under the direction of the veterinary
would rather the animal have access to the surgeon (Medicines Regulations (SR 1984/143) 7
medication. From our observations, the most August 2009; Regulation 42 (2)). This is in contrast
common reason for prescriptions being written by to the tighter regulations in place in community
veterinarians was if the patient required a medicine pharmacy. Dispensary technicians, pharmacy
that the veterinary practice did not have in stock, or graduates, pharmacy technicians and students can
a medicine that was not commonly used. only dispense prescription medicines under the
direct supervision of a pharmacist (Medicines
Although veterinarians and their staff performed Regulations (SR 1984/143) 7 August 2009;
almost all dispensing, community pharmacies were Regulation 42 (1A)) and all of their actions must be
sometimes used. There were two main reasons for authorized as correct before the medication can
this: lower price and wider range of products leave the dispensary. Pharmacists also have ethical
available. Pharmacies stock a more extensive range responsibilities to check that the doses are correct
of medicines than veterinary practices, due to the and the prescribed medicine is appropriate for the
vast array of human medical conditions requiring patient, before dispensing the medicine. If there is
treatment. The most likely reason for this difference any uncertainty with these aspects or any
is the government regulatory body (PHARMAC) component of the prescription, the pharmacist is
funds many high-demand human medicines in New obliged to contact the prescriber. In veterinary
Zealand, whereas veterinary medicines are funded practice, as it is the veterinarian who prescribes the
directly by the consumer. medicine and does the majority of the dispensing,
There appear to be no regulations or guidelines they are responsible for ensuring that the dose and
about the period of supply for medicines dispensed medicine is appropriate for their patients. Thus, for
animals, the veterinarian carries out the roles of
both doctor and pharmacist, which means there is included in the veterinary setting. The difference
no verification of dosage or suitability by an evident with labeling of medicines intended for
independent source. Pharmacists are in a suitable animals is the inclusion of the terms “For Animal
environment to provide medicines to the owners of Treatment Only” and “Keep Out of Reach of
animals, as they have both knowledge of medicines Children”. This could be easily incorporated into the
and access to supplies. Although we observed that label when dispensed in the pharmacy setting, and
it was not a common practice, there is definite is not a significant barrier that would prevent large
potential for pharmacists to play a role in the quantities of animal medicines from being
veterinary field, as has been suggested by other dispensed in a community pharmacy.
4,7
authors.
In Dunedin, both veterinarian clinics and DISCUSSION
pharmacies source the majority of their medicines
from the same supplier. This wholesaler does not Records are valuable sources of information as well
restrict each professions to obtaining only as legal documents, it is therefore imperative to
medicines specific to their line of work, as both utilize and maintain easily accessible organised
professions have access to both human and records. Findings indicated that like pharmacy
veterinary medicines. Where a product is not readily records, veterinary records were categorized
accessible, the veterinarians and pharmacists must primarily under the clients’ name and included a
either compound the product, order a suitable patient history. In both disciplines records are stored
formulation or change the medication. The general electronically with the use of practice-based
consensus is that on-site compounding is being computer programs designed specifically for use in
phased out in both professions in favor of either pharmacy or veterinary practice. Because of
manufactured formulations that can be ordered their dual role as prescribers and dispensers for
through compounding companies. In the case of animals, veterinary software was often more
veterinary medicine, compounding may be ordered complex than pharmacy dispensing software,
specific to the patient through companies such as because it includes medical history as well
Optimus, a compounding pharmacy that specializes prescribing history. Like pharmacy dispensing
in extemporaneous compounding of both veterinary software, veterinary programs allow for the
and human medicine. Pharmacists on the other construction of labels for medication. Unlike
hand are frequently required to compound these pharmacy dispensing software, veterinary programs
items for individual patients if the product is not included fewer features like interaction prompting
readily available. and essential medical information. The prescribing
veterinarian must also keep records of each
The common classes of antimicrobials prescribed in prescription issued for five years and these should
a veterinary setting (Table 2) are also routinely be cross-referenced to the details of the associated
prescribed for use in humans and are regularly veterinary consultation (ACVM Standard for
dispensed in community pharmacies. This highlights Prescription Animal Remedy Veterinary Medicines,
the potential for pharmacist involvement in Section 2.43). This is in contrast to a pharmacy
veterinary medicine with the provision of a more where prescriptions must be stored for 10 years, on
affordable and convenient service for animal site for three years in original form and then for a
owners. The emergence of antimicrobial resistance further seven years to comply with legal standards
emphasizes the importance of ensuring the correct (Health (Retention of Health Information)
and appropriate use of antibiotics by veterinarians.8 Regulations SR1996/343). In both veterinary clinics
and pharmacies, records were kept a minimum of
With respect to labeling of medicines, the 10 years and were usually maintained for the life of
pharmacist must maintain a thorough, succinct the patient, this complies with Section 45 of the
process to produce a label adequate to the patient Medicines Act 1981, which states that every person
for both legal and ethical requirements. In veterinary in a business who supplies medicine must keep
practice, this process is less regulated with the records for such period as may be prescribed.
labels being made either by the veterinarian at the
time of dispensing or authorization or by verbal Veterinary prescribing is the process of selecting a
sanctioning to veterinary nurses. Labeling of suitable medication and treatment regime tailored to
veterinary medicine has additional requirements to the animal’s needs. Legally, medicines that are
prescribed medicines intended for human use. classified as ‘prescription only’ may only be
Table 3 shows the common requirements that are dispensed by a veterinarian or pharmacist following
requisites for the labeling of medicines in both a clinical assessment by the veterinarian and may
professions, and additional information that must be only be dispensed or sold in accordance with a
9
Table 3. Legal labeling requirements for inclusion on veterinary products.
Additional veterinary
Essential requirements regardless of profession
labels required
• Dispensing practice name, address and contact phone number • “For Animal Use Only”
• Name of prescriber • “Keep out of reach of
• Patient name Children”
• Product name and strength
• Quantity
• Date dispensed
• Directions for use
• Essential medical information
prescription. Although it is not common practice for Our study concluded that veterinarians in this region
veterinarians to write prescriptions to be filled in themselves did the majority of the dispensing
community pharmacies, it does occur in specific including selection of the medicine from the supply
situations. In many instances it is more economical area, packaging the appropriate quantity and
for the patient if the veterinarian writes a labeling the medicine before giving it to the
prescription, as the cost of the medicine dispensed animal/owner. In some instances, veterinary nurses
by pharmacies is usually lower than the cost at the would aid in the dispensing of routine medication,
5
veterinary clinic. If the veterinarian is aware of under the direction of the veterinarian. Legally an
financial hardship with their clients, then they may agent or employee at a veterinary surgeon may
take this into consideration and opt for this course of dispense a prescription medicine for the treatment
action. While veterinarians acknowledged that it of an animal under the direction of the veterinary
was not routine practice, they agreed that they surgeon (Medicines Regulations (SR 1984/143) 7
would rather the animal have access to the August 2009; Regulation 42 (2)). This is in contrast
medication. From our observations, the most to the tighter regulations in place in community
common reason for prescriptions being written by pharmacy. Dispensary technicians, pharmacy
veterinarians was if the patient required a medicine graduates, pharmacy technicians and students can
that the veterinary practice did not have in stock, or only dispense prescription medicines under the
a medicine that was not commonly used. direct supervision of a pharmacist (Medicines
Regulations (SR 1984/143) 7 August 2009;
Although veterinarians and their staff performed Regulation 42 (1A)) and all of their actions must be
almost all dispensing, community pharmacies were authorized as correct before the medication can
sometimes used. There were two main reasons for leave the dispensary. Pharmacists also have ethical
this: lower price and wider range of products responsibilities to check that the doses are correct
available. Pharmacies stock a more extensive range and the prescribed medicine is appropriate for the
of medicines than veterinary practices, due to the patient, before dispensing the medicine. If there is
vast array of human medical conditions requiring any uncertainty with these aspects or any
treatment. The most likely reason for this difference component of the prescription, the pharmacist is
is the government regulatory body (PHARMAC) obliged to contact the prescriber. In veterinary
funds many high-demand human medicines in New practice, as it is the veterinarian who prescribes the
Zealand, whereas veterinary medicines are funded medicine and does the majority of the dispensing,
directly by the consumer. they are responsible for ensuring that the dose and
There appear to be no regulations or guidelines medicine is appropriate for their patients. Thus, for
about the period of supply for medicines dispensed animals, the veterinarian carries out the roles of
by veterinarians. However, when veterinarians both doctor and pharmacist, which means there is
prescribe medicines to be dispensed by no verification of dosage or suitability by an
pharmacists, there is legislation regarding the independent source. Pharmacists are in a suitable
period of supply. This is due to a legal difference environment to provide medicines to the owners of
between an “authorization” and a “prescription” of a animals, as they have both knowledge of medicines
veterinary medicine. When veterinarians, or their and access to supplies. Although we observed that
staff, dispense medicines this is referred to as an it was not a common practice, there is definite
authorization (a documented instruction authorizing potential for pharmacists to play a role in the
the sale or use of a medicine by a veterinarian veterinary field, as has been suggested by other
4,7
(Agricultural Compounds and Veterinary Medicines authors.
(ACVM) Standards for Prescription Animal In Dunedin, both veterinarian clinics and
Remedies, Section 2.4.3). A prescription refers to a pharmacies source the majority of their medicines
documented instruction to dispense a medication from the same supplier. This wholesaler does not
and is usually intended for pharmacists or traders. restrict each professions to obtaining only
In the latter case, the medicine must be dispensed medicines specific to their line of work, as both
within 30 days of the date of writing and the professions have access to both human and
prescription must specify a period of treatment, not veterinary medicines. Where a product is not readily
exceeding six months (ACVM) Standards for accessible, the veterinarians and pharmacists must
Prescription Animal Remedies, Section 2.4.3). Thus either compound the product, order a suitable
there are more strict requirements for medicines formulation or change the medication. The general
dispensed to animals by community pharmacists consensus is that on-site compounding is being
compared with those dispensed by veterinarians. phased out in both professions in favor of
Medicines dispensed to human patients are further manufactured formulations that can be ordered
restricted by legislation. Doctors are restricted to through compounding companies. In the case of
prescribing a maximum of three months supply of a veterinary medicine, compounding may be ordered
medicine at any one time. Depending on the specific to the patient through companies such as
medication prescribed and the funding Optimus, a compounding pharmacy that specializes
requirements, a pharmacist may dispense the total in extemporaneous compounding of both veterinary
three months supply at once, or as a monthly and human medicine. Pharmacists on the other
dispensing. Controlled drugs for humans have their hand are frequently required to compound these
own requirements. These can be prescribed for a items for individual patients if the product is not
maximum of one months supply and dispensed in readily available.
quantities sufficient for either one week or 10 days
treatment.
The common classes of antimicrobials prescribed in Hospital Pharmacists, the International College of
a veterinary setting (Table 2) are also routinely Veterinary Pharmacy and Veterinary Pharmacists
prescribed for use in humans and are regularly Group of the Royal Pharmaceutical Society of Great
dispensed in community pharmacies. This highlights Britain have also been established to promote and
the potential for pharmacist involvement in enhance the continued development of veterinary
veterinary medicine with the provision of a more pharmacy. In the United Kingdom, there are
affordable and convenient service for animal Prescribing Advisors who are pharmacists who work
owners. The emergence of antimicrobial resistance with general practitioners and primary care clinics to
emphasizes the importance of ensuring the correct provide information on medicines management. The
8
and appropriate use of antibiotics by veterinarians. advice includes consistent best practice in
prescribing and cost effective treatments that have
With respect to labeling of medicines, the the desired health outcomes for patients. We
pharmacist must maintain a thorough, succinct suggest that this is potentially a role that
process to produce a label adequate to the patient pharmacists could develop in association with
for both legal and ethical requirements. In veterinary veterinarians in New Zealand. The creation of such
practice, this process is less regulated with the specialized positions would also require the
labels being made either by the veterinarian at the education and training of pharmacists interested in
time of dispensing or authorization or by verbal the role of veterinary prescriber in subject areas
sanctioning to veterinary nurses. Labeling of including animal anatomy, physiology,
veterinary medicine has additional requirements to pharmacokinetics, animal behavior
3
and
prescribed medicines intended for human use. compounding for animal patients.
Table 3 shows the common requirements that are
requisites for the labeling of medicines in both As pharmacists are the medication experts in the
professions, and additional information that must be community, they are familiar with the different
included in the veterinary setting. The difference formulations and applications of medicines. In most
evident with labeling of medicines intended for instances, the medications used in the veterinary
animals is the inclusion of the terms “For Animal setting are the same as those used for the
Treatment Only” and “Keep Out of Reach of treatment of human conditions, and will not require
Children”. This could be easily incorporated into the an extensive expansion into different product lines
label when dispensed in the pharmacy setting, and as current human medications can be utilized within
is not a significant barrier that would prevent large the different species. Integrating this knowledge
quantities of animal medicines from being with the veterinarians’ extensive understanding of
dispensed in a community pharmacy. animals and animal conditions would create a vital
link between the two professions, allowing
pharmacists and veterinarians to work alongside
CONCLUSIONS each other to provide paramount health outcomes
Veterinary and pharmacy professions carry out for their respective patients.
overlapping roles with respect to protocols and
procedures regarding medication use in healthcare ACKNOWLEDGEMENTS
settings. Closer relationships between pharmacy
and the veterinary profession been established in We are most grateful to the veterinary practices in
some countries, in particular the United Kingdom Dunedin who enthusiastically participated in this
and the USA. For example, in the USA there are a study.
number of compounding pharmacies for veterinary
medicines and pharmacists on staff at veterinary
hospitals across the country. Professional CONFLICT OF INTEREST
organizations, such as The Society of Veterinary There were no conflicts of interest.
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