Item C219. Treatment Options for Genital Warts.

Medication Treatment Instructions Treatment Duration

Patient-applied treatments
Imiquimod
5% (or 3.75%) cream
Podofilox
0.5% solution or gel
Apply at bedtime 3 times Up to 4 months
a week; wash off in the
morning.
Apply twice daily for 3 Up to 4 weeks
days; then 4 days with no
treatment; then repeat

Sinecatechins Apply ointment 3 times Up to 4 months

15% ointment daily

Provider-applied treatments
Trichloroacetic acid Apply a small amount to Can repeat weekly
80%-90% solution wart; allow to dry. until warts resolve

Cryotherapy (liquid Provider applies liquid More than 1 treatment

nitrogen); provider nitrogen to lesions may be needed
should be trained
Adapted from Workowski KA, Bolan GA; Centers for Disease Control and Prevention. Sexually trans-
mitted diseases treatment guidelines, 2015. MMWR Recomm Rep. 2015;64(RR-03):1-137.