Season 1, Episode 11: Blood Hungry

Original Air Date14 December 2005 The BAU team must profile a delusional killer in rural Tennessee, and a family member protecting him puts a child at risk.

Season 4, Episode 5: Catching Out

Original Air Date29 October 2008 A man is jumping trains along Highway 99, brutally killing couples in their homes whenever he stops.

Season 4, Episode 8: Masterpiece

Original Air Date19 November 2008 A serial killer turns himself in and challenges the team to find five people he has hidden somewhere before they die.

Season 4, Episode 9: 52 Pickup

Original Air Date26 November 2008 A greatly sadistic serial killer who disembowels women and forces them to clean it up before killing them proves difficult to catch thanks to his social charm and simple, yet clever, disguises.

Season 4, Episode 10: Brothers in Arms

Original Air Date10 December 2008 Morgan, an ex-cop, takes it personally when a serial killer targets police officers in Phoenix, Arizona.

Season 4, Episode 11: Normal

Original Air Date17 December 2008 A serial killer known as the Road Warrior is gunning down blonde women on roads in Orange

County, California and the BAU suspect that the victims are surrogates and that it's only a matter of time before he kills the real one.

Season 4, Episode 12: Soul Mates

Original Air Date14 January 2009 To his Sarasota Florida neighbors, William Harris is a model family man and upstanding citizen. However, he is taken into custody on suspicions of being the murderer of young women, accusations which followed him from Atlanta, where his family was forced to moved from because of the previous accusations. Harris denies any involvement and is confident that his wife can (and will) post the $5 million bail as she does not believe he had anything to do with the murders. The victims are held for two days before they are strangled to death. The victims are also alternately a white woman then a black woman. The latest possible victim is Missy Dewalt, who has been missing for a few hours. However, her dead body is found within the day, the time of death being when Harris was in custody. Based on a secret blog found deleted from Harris' computer and Missy's death, the BAU are certain that Harris is the murderer but has an accomplice. Harris' daughter, Andrea, grows suspicious of his involvement in the murders and sees the signs provided to her by the BAU of her father's possible accomplice.

Season 4, Episode 15: Zoe's Reprise

Original Air Date18 February 2009 A copycat serial killer is recreating murder techniques used by famous killers from the past.

Season 4, Episode 16: Pleasure Is My Business

Original Air Date25 February 2009 A high priced call girl that is killing her clients must be found and stopped.

Season 4, Episode 17: Demonology

Original Air Date11 March 2009 Prentiss learns from an old friend, John Cooley, that their mutual friend, Matthew Benton, just died from a heart attack. Prentiss had not seen either man in several years, both for different reasons. John also mentions that Matthew thought he was going to be killed just like "T.

Valentine". In searching, Garcia does find someone matching that name in the area who recently died from dehydration. There are similarities between the two deaths but no medical rationale for tying the two together as murders. A third person in the area then dies in a similar way but again no medical indication of an unnatural death or rationale tying the death to the first two. However, Prentiss and Rossi, in particular within the team, are certain the three deaths are related and that they are indeed murders. They have to tread lightly and carefully since the families of the deceased refuse to speak to the FBI - especially Matthew's family who know, and do not like, Prentiss - and since there is no official case as the police have not sanctioned one. The investigation gets more complicated for the team when they find who they believe is the murderer.

Season 4, Episode 19: House on Fire

Original Air Date25 March 2009 When the kill count of a mass-murdering arsonist active in a small town reaches 31, the BAU are called in.

Season 4, Episode 22: The Big Wheel

Original Air Date29 April 2009 The team tracks down a highly obsessive-compulsive killer who targets blonde women and leaves messages to the police asking them to stop him.