PME PARTE IMPORTANT QUESTIONS UNIT 5 Andy luperrecli a UNIT- 5 _PaTHopHysoLoay ———E Write the — Pathophysiolagy ‘of Tuberculosis. Accosding to_WHo Tihtalossis_mast_preien infotinn di dsme i le_and leading. killer_at leat 3 million deaths annually 9} Toberculosis_iS an infection caused by a bacteria named My@bacerium Tuberculosis Tuberulosis (78) most _offen_affeds the ngs charaderized by aymptoms _such_0% acute inflammation, issue necrosis ete. Ine yet jo Causes Tuberculosis _{s_mainly caused by 0. bodetia “called -Mycobadletum (Tuberculosis. cee ece TB is _speais_fom_oe_fessf0-obahosgh a Undesnvttition Bactenal Infection oe a ‘Smokin : — 7 Close _ contact with “person sufesing fun rm - Tntoke of Unpasteurised Cow MilkClassification of Tuberulosis te iat HU —— Dratercatasis | - Extra _fulmonary TB e Lymph Node TR Plu TR FMiiory TB 1 f_ Pencarclied 78 SI Grostointestina! Ta | —Thbervloua Meningitis Pathogenesis OF Tubertulasis Litt Infection or _Ftimary _Thfection | , LEniy of mic organism through droplet nuclei] } : = _ | Bacteia_is transmitted to Alveoti through _ Aisways | | _[LDeposition and Multiplicahion of Bacteria_| __ | So |} Badetias are also transported 4a other parts | oF Dody via blood stream € Phagocytosis by Nevtrophills -¢ Macrophages Pose onapsara __Symptoms_of Toberculesis eos Hemoptysis._ a B \eakness_ - oe Fabique. : 7 7 loss of Apetite. arenes . Rise_in Temperoture Bee eee Chest_fhin 7 Nign Sweats Grmplications i Plan_of _Treo}ment =e © | Rest Die amon i ad: Go iNolpitbn eee iene Maintoinane - —— s Rirst_Line Dr Streptomycin, Isoniazid, Etnambutal © second Line Pgs: fora Amina Salicyic Acid, Kanamycin. aapsara I _ _ - a -® (Define Urinary Tract Tnfeons. i e fectiona ate. Amongst most common __bactena) linfectiong of human . + © |UTT Thfectiona is defined aa a ‘condition in_which —bactenia Invade, land _grow inthe urinary track. . © | A Uni tn_any par —_usinary _Aystern_ eg.—_kidnegys. Uretera., Bladder 2 Urethra. tac blader So te eton,_tnet_the—lower—unay and Urethra _ utr tan be cassifed_on_the boas of two coleganes 2 = SS e basis of Clinical Features, - in Be i oO inn icaked_ UTL a eagtitel lon te basis of Anatomical site es _|On the bosis of anatomical site UTIs are_of three types © |Gytisis _: Thfedions of Uninary Bladder @ \Uretnntis + Tnfechions of Urethra = ®. Pyelonephritis : Infections of Kidneyapsara Date:_—- Causes @|\More than 907. of uTt cases are a “jype of _bodetia called Escherichia. Gli CE OW) : © (These bacteria normally tive in. the bowel € found amy 2 Uninary Tract Infections _ not occus when E+ coli Dadetia-get - Into_the_usine_€ begin to ‘The infections — Usually starts _at es png of wen guy — - ee is] EB | 7 Pathogenesis; : eo Chronic Tnfectiona of skin , Respiratory Tract € ; Gastrointestinal Tract | + ; 7 Bacteria's, entes load cteculotiong | an - Blood _enterg Kidney for filteration | . { Baderia moves from Cortex +o fenol_medutlla = Bactena (esidea roliferater,__Sumptoms OF UTIs = A pessistent_urge tounge Busing or Pain i ination. Fossing smoll_Omount_of _unine a 2 Reddish, bsownish Urine. Complications, Recurrent Infections ‘ Pesmanent Kidney Damage. Urethral_Namrowing : Taft Blood Poisoning E eee ey : 5© Paice patsy of os 8 AIDS—_'5_a_type_of Sexually Transmit Disease (sto) itted__dlisease are ‘ilness _thot_have significant Probability oF _transmiston_blw _humans, by means of _serual_s Including _vagina © | AlOS tefered to aged “Tinmunodefcenay Disease. — | _Intercounge _, oral_sex ete. _ ——9TE IS a_disease_causedl_by Human Trmunodefiaency Vina_Chnde eg UI at lends tO of _Hiv_Tnfections - _ ‘The_initial stage of primary infection occurs. within week of __ oqpining tre _viva_2_this_stage _{s_chovacteniaed by a Flu ike illness that resolve_within weeks. The _middle__stage of chronic agymptomatic _tnfectian lost Sx le-4o years without treatment The final stage is symptomatic. infection in which vody's immune | system ts suppressed and camplicofiong._clevelops callec| Alps .Ca + Lauses apsara AIDS _is_mainly Caused _by HIV. Cian Tama — = = Bie ee cena roe eee - £2 ° They_are_of mainly two types: ; HIV 1 [HIV OD : a HIV - -I: Tt is_mask common ins. Europe -€_Ceniral_ Afsica —— Hiv - I! Tt ism Pathorhysiolngy - - s | HIV particles bindg with feeptows on 2 [lymphocyte £.c04).cell_surRace | Liter wa slarts Reverse Transuaption, — | oo [it RWA_cmveris to viral ona _| {—_____. a Virol ONA Gmbines with helpes- 7 : a ao TY Cell_DNA - - Replication oF HIV - Helpes - Ty ll produces new viral Components :apsara Development of New Virol Rarticles [. eee Tifeted helpes- Ta elle destroyed - v Thal Stage Thfkctiona, | Final Stage Infections, - CAIDs) _ Symptoms, © | Rapid Weight Loss j 2 Dry Cough a @ || Fever 4 @||Nignt Sweats - - ° Unexplained| faligue De eo) Dame tal — = || Diarrhoe that More thon week @||Navsea Oo _@ || Vomi tng - _ . Serwres = © | Neurological Disosderg © | Severe Headaches a © | Gma__ =i a ——THANK IE ORICHOOSING|IMPEREECT/PHARMACY/ASY OURISTUDYIPARTNER, A> lupenrecl CETTE Ina? © TERT | > JRIMPERFEC T2PHARMACY,