Sometimes, depression symptoms persist, even after months of therapy
and medication. If you have treatment-resistant depression, your care team may recommend:
• Electroconvulsive therapy (ECT). This treatment delivers electrical
impulses to the brain to trigger a seizure, which changes electrical activity in your brain. You’ll be anesthetized during the procedure, so you won’t feel anything at all. Keep in mind that modern ECT is very different from the “shock therapy” administered in the mid-20th century. • Transcranial magnetic stimulation (TMS). Also called repetitive transcranial magnetic stimulation (rTMS), this treatment delivers magnetic impulses to your brain, which is believed to help stimulate nerves in the brain and increase brain activity. • Vagus nerve stimulation. This treatment, which stimulates your vagus nerve through a device implanted in your chest, is believed to help restore the balance of brain chemicals linked to depression.