Guidance (/guidance/ipg756)

Tools and resources (/guidance/ipg756/resources)

Information for the public (/guidance/ipg756/informationforpublic)

Evidence (/guidance/ipg756/evidence)

History (/guidance/ipg756/history)

Overview (/guidance/ipg756)

1 Recommendations

2 The condition, current treatments and procedure

(/guidance/ipg756/chapter/2-The-condition-current-treatments-and-
procedure)

3 Committee considerations (/guidance/ipg756/chapter/3-Committee-

considerations)

Guidance

1 Recommendations
1.1 Evidence on the safety of focal therapy using high-intensity
focused ultrasound for localised prostate cancer is adequate,
but evidence on its efficacy is limited. Therefore, this procedure
should only be used with special arrangements for clinical
governance, consent, and audit or research. Find out what
special arrangements mean on the NICE interventional
procedures guidance page
:
 (https://www.nice.org.uk/about/what-we-do/our-
programmes/nice-guidance/interventional-procedures-
guidance/recommendations).

1.2 Clinicians wanting to do high-intensity focused ultrasound for

localised prostate cancer should:

Inform the clinical governance leads in their healthcare

organisation.

Give people (and their families and carers, as appropriate)

clear written information to support shared decision making
(https://www.nice.org.uk/about/what-we-do/our-
programmes/nice-guidance/nice-guidelines/shared-decision-
making), including NICE's information for the public
(https://www.nice.org.uk/guidance/IPG756/InformationForPublic).
Use the recommendations in NICE's guideline on diagnosing
and managing prostate cancer
(https://www.nice.org.uk/guidance/ng131) for information on
treatment options and decision support.

Ensure that people (and their families and carers, as

appropriate) understand the procedure's safety and efficacy,
and any uncertainties about these.

Audit and review clinical outcomes of everyone having the

procedure. The main efficacy and safety outcomes identified
in this guidance can be entered into NICE's interventional
procedure outcomes audit tool
(https://www.nice.org.uk/About/What-we-do/Our-
Programmes/NICE-guidance/NICE-interventional-
procedures-guidance) (for use at local discretion).

Discuss the outcomes of the procedure during their annual

appraisal to reflect, learn and improve.

1.3 Healthcare organisations should:

:
 Ensure systems are in place that support clinicians to collect
and report data on outcomes and safety for everyone having
this procedure.

Regularly review data on outcomes and safety for this

procedure.

1.4 Patient selection should be done by a multidisciplinary team.

1.5 Further research could include registry data or randomised

trials. It should include details of patient selection, including
size and classification of tumour, technique used and long-term
outcomes such as quality of life.
: