Professional Documents
Culture Documents
HISTORY
Although not normally what first comes to mind, many forms of
human-derived agriculture clearly fit the broad definition of
"utilizing a biotechnological system to make products". Indeed,
the cultivation of plants may be viewed as the earliest
biotechnological enterprise. These processes also were included
in early fermentation of beer. These processes were introduced
in early Mesopotamia, Egypt, China and India, and still use the
same basic biological methods. In brewing, malted grains
(containing enzymes) convert starch from grains into sugar and
then adding specific yeasts to produce beer. In this process,
carbohydrates in the grains broke down into alcohols, such as
ethanol. Later, other cultures produced the process of lactic acid
fermentation, which produced other preserved foods, such as soy
sauce. Fermentation was also used in this time period to produce
leavened bread. Although the process of fermentation was not
fully understood until Louis Pasteur's work in 1857, it is still the
first use of biotechnology to convert a food source into another
form.
APPLICATIONS OF BIO-TECHNOLOGY
Biotechnology has applications in four major industrial areas,
including health care (medical), crop production and agriculture,
non-food (industrial) uses of crops and other products (e.g.,
biodegradable plastics, vegetable oil, biofuels), and
environmental uses.
Industrial biotechnology
is the application of biotechnology for industrial purposes,
including industrial fermentation. It includes the practice of using
cells such as microorganisms, or components of cells like
enzymes, to generate industrially useful products in sectors such
as chemicals, food and feed, detergents, paper and pulp, textiles
and biofuels. In the current decades, significant progress has
been done in creating genetically modified organisms (GMOs)
that enhance the diversity of applications and economical
viability of industrial biotechnology. By using renewable raw
materials to produce a variety of chemicals and fuels, industrial
biotechnology is actively advancing towards lowering
greenhouse gas emissions and moving away from a
petrochemical-based economy.
Synthetic biology
Is considered one of the essential cornerstones in industrial
biotechnology due to its financial and sustainable contribution to
the manufacturing sector. Jointly biotechnology and synthetic
biology play a crucial role in generating cost-effective products
with nature-friendly features by using bio-based production
instead of fossil-based.
MEDICINES
Medicine is the science and practice of caring for a patient,
managing the diagnosis, prognosis, prevention, treatment,
palliation of their injury or disease, and promoting their health.
Medicine encompasses a variety of health care practices evolved
to maintain and restore health by the prevention and treatment
of illness. Contemporary medicine applies biomedical sciences,
biomedical research, genetics, and medical technology to
diagnose, treat, and prevent injury and disease, typically through
pharmaceuticals or surgery, but also through therapies as
diverse as psychotherapy, external splints and traction, medical
devices, biologics, and ionizing radiation, amongst others.
A) Chief complaint (CC): the reason for the current medical visit.
These are the symptoms. They are in the patient's own words
and are recorded along with the duration of each one. Also
called chief concern or presenting complaint.
B) Current activity: occupation, hobbies, what the patient
actually does.
C) Family history (FH): listing of diseases in the family that may
impact the patient. A family tree is sometimes used.
D) History of present illness (HPI): the chronological order of
events of symptoms and further clarification of each
symptom. Distinguishable from history of previous illness,
often called past medical history (PMH). Medical history
comprises HPI and PMH.
E) Medications (Rx): what drugs the patient takes including
prescribed, over-the-counter, and home remedies, as well as
alternative and herbal medicines or remedies. Allergies are
also recorded.
F) Past medical history (PMH/PMHx): concurrent medical
problems, past hospitalizations and operations, injuries, past
infectious diseases or vaccinations, history of known allergies.
G) Review of systems (ROS) or systems inquiry: a set of additional
questions to ask, which may be missed on HPI: a general
enquiry (have you noticed any weight loss, change in sleep
quality, fevers, lumps and bumps? etc.), followed by questions
on the body's main organ systems (heart, lungs, digestive
tract, urinary tract, etc.).
H) Social history (SH): birthplace, residences, marital history,
social and economic status, habits (including diet,
medications, tobacco, alcohol).
I) The physical examination is the examination of the patient for
medical signs of disease that are objective and observable, in
contrast to symptoms that are volunteered by the patient and
are not necessarily objectively observable. The healthcare
provider uses sight, hearing, touch, and sometimes smell (e.g.,
in infection, uremia, diabetic ketoacidosis). Four actions are
the basis of physical examination: inspection, palpation (feel),
percussion (tap to determine resonance characteristics), and
auscultation (listen), generally in that order, although
auscultation occurs prior to percussion and palpation for
abdominal assessments.
10) Skin
Veterinary medicine was, for the first time, truly separated from
human medicine in 1761, when the French veterinarian Claude
Bourgelat founded the world's first veterinary school in Lyon,
France. Before this, medical doctors treated both humans and
other animals.
Branches
Working together as an interdisciplinary team, many highly
trained health professionals besides medical practitioners are
involved in the delivery of modern health care. Examples include:
nurses, emergency medical technicians and paramedics,
laboratory scientists, pharmacists, podiatrists, physiotherapists,
respiratory therapists, speech therapists, occupational
therapists, radiographers, dietitians, and bioengineers, medical
physicists, surgeons, surgeon's assistant, surgical technologist.
Basic sciences
Anatomy is the study of the physical structure of organisms.
In contrast to macroscopic or gross anatomy, cytology and
histology are concerned with microscopic structures.
CRISPR
Tissue Nanotransfection
New science may have the ability to heal people with a single
touch. Sound too good to be true? It’s not. Tissue
nanotransfection works by injecting genetic code into skin
cells, which turns those skin cells into the other types of cells
required for treating diseases. In some lab tests, one touch of
TNT completely repaired the injured legs of mice over a period
of a few weeks by turning skin cells into vascular cells. And
reportedly, this biotech can work on other types of tissue
besides skin. The potential for this type of gene therapy is
huge, from helping car crash victims to active duty soldiers.
Medical biotechnology has made this advancement possible,
and the continued research and testing will only help improve
this tech and adopt it across hospitals and medical centers.
Transgenic Animals
Although several recombinant proteins used in medicine are
successfully produced in bacteria, some proteins need a
eukaryotic animal host for proper processing. For this reason,
genes have been cloned and expressed in animals such as
sheep, goats, chickens, and mice. Animals that have been
modified to express recombinant DNA are called transgenic
animals
Transgenic Plants
Manipulating the DNA of plants (creating genetically
modified organisms, or GMOs) has helped to create desirable
traits such as disease resistance, herbicide, and pest
resistance, better nutritional value, and better shelf life .Plants
are the most important source of food for the human
population. Farmers developed ways to select for plant
varieties with desirable traits long before modern-day
biotechnology practices were established.
Privacy Concerns
Privacy is an ongoing issue in our technology world, but
reading someone’s DNA seems to be a giant privacy breach.
Imagine a doctor looks at a young child’s DNA and finds out
they are likely to develop a heart disease or terminal issue.