Solutions and Applications No.

1014
ASP2000 Sample Preparation and Measurement System for
Dissolution and Content Uniformity Samples using UV Analysis
ASP2000 can use sealed tubes or vials.
High torque motors and drives allow septum piercing so
keeping solutions clean free from atmospheric contamination.

Calculate and display results in the units and format appropriate for the application

When Dissolution and Content Uniformity samples need to be prepared and

measured by UV, the ASP2000 automates this tedious time consuming task

§ Large throughput measures over 300 solutions

ALS provides the widest range of automated
systems for Pharmaceutical Analysis. This
system uses the ASP2000 XYZ Single Probe
sampler to automatically prepare Standards
and Samples and measure on the UV of
your choice. Results are calculated and
displayed in real time.
§ Runs multiple batches sequentially each with its
own unique Lot Number
§ Analytical Dilution with microlitre volumes as
required
§ Measure Standard once and use for multiple
batches
§ Use spectrophotometers from ALS SP700, Agilent
8453, Agilent Cary 50/60, Jena Specord, Perkin
Elmer Lambda 25/35/45, Shimadzu UV1600/1700,
1800, 2401/2501, Thermo E300.
§ Add Reagent to stabilise or enhance Sample
detection (Reagent Addition)
§ Analysis from sealed vials to avoid vaporisation
and reduce atmospheric contamination
§ Professional result reports
Automatically Prepare Standards from Stock Solution with unlimited dilution ratios which are
consistently more reproducible than with manual systems.

Dilution
1 in 2 1 in 4 1 in 5 1 in 10 1 in 10 1 in 2

Stock Solution 2 4 5 10 100 200

Dilution Ratio

ALS systems are very flexible and can be applied to

pharmaceutical analysis in R&D, Formulation and most
importantly for Quality Control providing high sample
throughput, reduction in manpower and return on
investment.
The pharmaceutical industry requires quality systems.
ALS ASP2000 analysis systems provide features compliant
with quality standards… Standard Checks, Preparation of
Standards from Stock solution, Quantification using
Calibration Curve, full compliance with 21 cfr Part 11.
All ALS systems are provided with IQ, OQ and optional
PQ fully in line with pharmaceutical testing Experience standard preparation with
requirements. Linear Correlation Coefficients better
Systems can be configured using instruments from than 0.9997 every time.
different manufacturers to get the best possible
solutions.

Overall Advantages
§ High precision and reproducible standard preparation and measurement
§ High Sample Throughput with unattended automation reduces labour costs
§ More accurate and reproducible results than with manual systems
§ Less solvent usage and Health and Safety risks

Automated Lab Systems

Unit 2 Pinecopse, Nine Mile Ride
Wokingham, Berkshire
RG40 3ND, UK
LAB SYSTEMS
Tel: +44 1344 780141; Fax: +44 1344 563039
www.auto-labsystems.co.uk