Sample Questions on GI Pharmacology

Choose one correct answer:

1. A 52-year-old patient is diagnosed with ovarian cancer. She begins using cisplatin
but becomes nauseous and suffers from severe vomiting. Which of the following
medications would be the most effective to counteract the emesis in this
patient?

A. Nabilone.
B. Dolasetron.
C. Prochlorperazine.
D. Dexamethasone.

2. A couple celebrating their 40th wedding anniversary are given a trip to Peru to
visit Machu Picchu. Due to past experiences while traveling, they ask their doctor to
prescribe an agent for diarrhea. Which of the following would be effective?

A. Omeprazole.
B. Loperamide.
C. Famotidine.
D. Lorazepam.

3. Which of the following drugs has been known to cause discoloration of the
tongue?

A. Amoxicillin.
B. Omeprazole.
C. Bismuth compounds.
D. Lubiprostone.

4. Which of the following drugs is the least tolerated for the treatment of
constipation:

A. Castor oil.
B. Methylcellulose.
C. Lactulose.
D. Docusate.

5. Mesoprostol is contraindicated in pregnancy because:

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 A. It is teratogenic.
B. it stimulates uterine contractions.
C. It worsens pregnancy-associated heart burn
D. None of the above.

6. A 45-year-old woman complains of persistent heartburn and an unpleasant, acid-

like taste in her mouth. The clinician suspects that she has gastroesophageal reflux
disease and advises her to raise the head of her bed 20 cm, not to eat for several
hours before sleeping, and to eat smaller meals. Two weeks later, she returns and
says the symptoms have subsided slightly but still are a concern. The clinician will
likely prescribe which one of the following drugs?

A. Aluminum hydroxide.
B. Dicyclomine.
C. Alprazolam.
D. Lansoprazole

7. Which class of these antiulcer drugs can eradicate Helicobacter pylori and
cure associated gastritis:

A. Sucralfate
B. Colloidal bismuth
C. H2 blockers
D. Anticholinergic drugs

8. Antacid: effective, but associated with systemic alkalosis:

A. Calcium carbonate
B. Sodium bicarbonate
C. Magnesium hydroxide
D. Aluminium hydroxide

9. All of the following are examples of H2 antagonists, EXCEPT:

A. Cimetidine

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 B. Citrizine
C. Ranitidine
D. Nizatidine
E. Famotidine

10. Phenothiazine prevents nausea and vomiting by inhibiting one of the

following receptors:

A. H1 receptor
B. Serotonine 3
C. Serotonine 5
D. Dopamine 2
E. Acetylcholine

Best Regards

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