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  • Antipsychotics Found To Lower Risk of Work Disability

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    The document summarizes a study that found: 1) Patients with first-episode psychosis have a lower risk of work disability during periods when taking antipsychotic medications compared to periods not taking them. 2) Long-acting injectable antipsychotics were associated with the lowest risk of work disability. 3) Nearly 46% of first-episode psychosis patients experienced work disability over an average 4.8 year follow-up period, and the risk was 35% lower when taking antipsychotics.

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    Antipsychotics Found to Lower Risk of Work Disability

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    The document summarizes a study that found: 1) Patients with first-episode psychosis have a lower risk of work disability during periods when taking antipsychotic medications compared to periods not taking them. 2) Long-acting injectable antipsychotics were associated with the lowest risk of work disability. 3) Nearly 46% of first-episode psychosis patients experienced work disability over an average 4.8 year follow-up period, and the risk was 35% lower when taking antipsychotics.

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    6 views1 page

    Antipsychotics Found To Lower Risk of Work Disability

    Uploaded by

    edsonhmiranda
    The document summarizes a study that found: 1) Patients with first-episode psychosis have a lower risk of work disability during periods when taking antipsychotic medications compared to periods not taking them. 2) Long-acting injectable antipsychotics were associated with the lowest risk of work disability. 3) Nearly 46% of first-episode psychosis patients experienced work disability over an average 4.8 year follow-up period, and the risk was 35% lower when taking antipsychotics.

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    C rren Iss e Frida , Oc ober 7, 2022 RSS FEED

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    A c c F d L e R fW
    D ab F F -E de P c S bscribe ia email

    Patients with first-episode psychosis have a Enter your Email

    lower risk of work disability during periods


    when taking antipsychotics compared with
    periods not taking the medications, a report S bscribe!
    published Thursday in The Ame ican J nal
    f P chia has found. The data—obtained Weekl Ne sle er
    from multiple Swedish databases on patients
    aged 16 to 45 who received a first nonaffective psychosis diagnosis—revealed
    that long-acting injectable (LAI) formulations may be particularly beneficial
    with regard to work disability.

    “Reducing work disability can reduce indirect costs of schizophrenia and


    Ne s From C rren Iss e
    enable patients to be involved in gainful employment and to experience a
    - Special Report: Bipolar Disorder II sense of accomplishment, a structure for daily routine, and the possibility of
    —Frequently Neglected, belonging to a social group through interactions with coworkers,” wrote Marco
    Misdiagnosed Solmi, M.D., Ph.D., of the University of Ottawa and colleagues.

    - Rare Neuropsychiatric Variants The study included 21,551 people (average age 29; 61% male) who received
    Present in 1% of Individuals
    a first nonaffective psychosis diagnosis (including schizophrenia, schizotypal,
    - APA’s Annnual Meeting and View delusional, and other non-mood psychotic disorders). The researchers
    Program compared work disability outcomes (sickness absence or disability pension)
    during periods when these patients were taking antipsychotics with periods
    when they were not between 2006 and 2016.
    Blog Archi e
    Nearly 46% of first-episode patients had work disability during the average
    ►
    ► 2023 (44) length of follow-up of 4.8 years, according to the researchers. The risk of
    2022 (246) work disability was 35% lower during antipsychotic use compared with no use
    ► by the same individuals.
    ► December (21)
    ►
    ► November (19) “The lowest adjusted hazard ratios emerged for long-acting injectable
    October (20) antipsychotics (aHR=0.46), oral aripiprazole (aHR=0.68), and oral olanzapine
    Naltrexone May Reduce Binge (aHR=0.68),” Solmi and colleagues wrote. “Long-acting injectables were
    Drinking in Sexual and... associated with lower risk than olanzapine, the most commonly used oral
    Study Highlights Children Most antipsychotic (aHR=0.68).”
    Likely to Be Taken ...
    Females With Autism More The researchers noted, “The mechanism through which antipsychotics are
    Likely Than Males to Deve... associated with better work functioning is currently unknown. We hypothesize
    Behavioral Therapy Plus that antipsychotics exert their action at least partially via their effect on
    Naltrexone-Bupropion positive symptoms, enabling psychosocial rehabilitation and/or return to
    Combi... functionality in a sizable subgroup of patients.”
    Neurological Complications
    Associated With Worse O... For related information, see the P chia ic Ne articles “LAI Antipsychotics
    AACAP Publishes Practice Beat Oral Meds for Preventing Relapse, Hospitalization” and “Study Calculates
    Guidelines on Child and A... Disability Caused by Schizophrenia.”
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